(6E,9E,12E,15E)-1,1,1-trifluorohenicosa-6,9,12,15-tetraen-2-one (BioDeep_00000913171)
代谢物信息卡片
(6E,9E,12E,15E)-1,1,1-trifluorohenicosa-6,9,12,15-tetraen-2-one
化学式: C21H31F3O (356.2327)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCC=CCC=CCC=CCC=CCCCC(=O)C(F)(F)F
InChI: InChI=1S/C21H31F3O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(25)21(22,23)24/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3/b7-6+,10-9+,13-12+,16-15+
描述信息
D004791 - Enzyme Inhibitors
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Guoyan Zhang, Shiliang Gui, Weiqun Wang, Dexin Meng, Qingmin Meng, Haiyan Luan, Rixin Zhao, Jiatian Zhang, Hongyu Sui. Acute stimulatory effect of tumor necrosis factor on the basolateral 50 pS K channels in the thick ascending limb of the rat kidney.
Molecular medicine reports.
2018 Nov; 18(5):4733-4738. doi:
10.3892/mmr.2018.9475. [PMID: 30221721] - Haiyan Luan, Peng Wu, Mingxiao Wang, Hongyu Sui, Lili Fan, Ruimin Gu. Effects of adenosine stimulation on the mRNA expression of CLCNKB in the basolateral medullary thick ascending limb of the rat kidney.
Molecular medicine reports.
2016 Nov; 14(5):4391-4398. doi:
10.3892/mmr.2016.5781. [PMID: 27748841] - Khairat B Y Elbaradie, Yun Wang, Barbara D Boyan, Zvi Schwartz. Sex-specific response of rat costochondral cartilage growth plate chondrocytes to 17β-estradiol involves differential regulation of plasma membrane associated estrogen receptors.
Biochimica et biophysica acta.
2013 May; 1833(5):1165-72. doi:
10.1016/j.bbamcr.2012.12.022. [PMID: 23305904] - Hong-Yu Sui, Hai-Yan Luan, Yu-Jie Liu. Involvement of protein kinase A activation and phospholipase A(2) inhibition in the adenosine-activated basolateral 50 pS K(+) channels in the thick ascending limb of the rat kidney.
Sheng li xue bao : [Acta physiologica Sinica].
2012 Aug; 64(4):449-54. doi:
. [PMID: 22907306] - Shumin Kong, Chengbiao Zhang, Wennan Li, Lijun Wang, Haiyan Luan, Wen-Hui Wang, Ruimin Gu. Stimulation of Ca2+-sensing receptor inhibits the basolateral 50-pS K channels in the thick ascending limb of rat kidney.
Biochimica et biophysica acta.
2012 Feb; 1823(2):273-81. doi:
10.1016/j.bbamcr.2011.10.007. [PMID: 22050992] - Li Zhang, Ning-Li Wang, Wei Zhang, Zhi-Jie Chang. [Suppression of cell proliferation by inhibitors to redox signaling in human lens epithelial cells].
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology.
2008 Jul; 44(7):622-8. doi:
. [PMID: 19040079] - Pasquale Pignatelli, Roberto Cangemi, Andrea Celestini, Roberto Carnevale, Licia Polimeni, Alessandra Martini, Domenico Ferro, Lorenzo Loffredo, Francesco Violi. Tumour necrosis factor alpha upregulates platelet CD40L in patients with heart failure.
Cardiovascular research.
2008 Jun; 78(3):515-22. doi:
10.1093/cvr/cvn040. [PMID: 18281372] - Akm A Sattar, Reazul Haque. Cytosolic PLA2 in zymogen granule fusion and amylase release: inhibition of GTP-induced fusion by arachidonyl trifluoromethyl ketone points to cPLA2 in G-protein-mediated secretory vesicle fusion.
Journal of biochemistry.
2007 Jan; 141(1):77-84. doi:
10.1093/jb/mvm007. [PMID: 17148545] - N Flamand, S Picard, L Lemieux, M Pouliot, S G Bourgoin, P Borgeat. Effects of pyrrophenone, an inhibitor of group IVA phospholipase A2, on eicosanoid and PAF biosynthesis in human neutrophils.
British journal of pharmacology.
2006 Oct; 149(4):385-92. doi:
10.1038/sj.bjp.0706879. [PMID: 16967052] - Lu-Cheng Cao, Thomas W Honeyman, Rachel Cooney, Lori Kennington, Cheryl R Scheid, Julie A Jonassen. Mitochondrial dysfunction is a primary event in renal cell oxalate toxicity.
Kidney international.
2004 Nov; 66(5):1890-900. doi:
10.1111/j.1523-1755.2004.00963.x. [PMID: 15496160] - Sara Fiorini, Maria E Ferretti, Carla Biondi, Barbara Pavan, Laura Lunghi, Guglielmo Paganetto, Luigi Abelli. 17Beta-eEstradiol stimulates arachidonate release from human amnion-like WISH cells through a rapid mechanism involving a membrane receptor.
Endocrinology.
2003 Aug; 144(8):3359-67. doi:
10.1210/en.2002-221106. [PMID: 12865314] - F Martini, S Riondino, P Pignatelli, P P Gazzaniga, P Ferroni, L Lenti. Involvement of GD3 in platelet activation. A novel association with Fcgamma receptor.
Biochimica et biophysica acta.
2002 Aug; 1583(3):297-304. doi:
10.1016/s1388-1981(02)00250-0. [PMID: 12176397] - Ho Jan Han, Soo Hyun Park, Jang Hern Lee, Byeong Cheol Yoon, Kwon Moo Park, Woong Chon Mar, Hye Jung Lee, Sung Keel Kang. Involvement of oxidative stress in bee venom-induced inhibition of Na+/glucose cotransporter in renal proximal tubule cells.
Clinical and experimental pharmacology & physiology.
2002 Jul; 29(7):564-8. doi:
10.1046/j.1440-1681.2002.03685.x. [PMID: 12060098] - M Schwemmer, O Sommer, E Bassenge. Angiotensin receptor blocker losartan suppresses platelet activity by interfering with thromboxane signaling.
Cardiovascular drugs and therapy.
2001 Jul; 15(4):301-7. doi:
10.1023/a:1012750430056. [PMID: 11800413] - R Manchanda, J M Kim, B K Tsang. Role of prostaglandins in the suppression of apoptosis in hen granulosa cells by transforming growth factor alpha.
Reproduction (Cambridge, England).
2001 Jul; 122(1):91-101. doi:
. [PMID: 11425333] - M E Handlogten, C Huang, N Shiraishi, H Awata, R T Miller. The Ca2+-sensing receptor activates cytosolic phospholipase A2 via a Gqalpha -dependent ERK-independent pathway.
The Journal of biological chemistry.
2001 Apr; 276(17):13941-8. doi:
10.1074/jbc.m007306200. [PMID: 11278341] - T Miyahara, H Tonoyama, M Watanabe, A Okajima, S Miyajima, T Sakuma, N Nemoto, K Takayama. Stimulative effect of cadmium on prostaglandin E2 production in primary mouse osteoblastic cells.
Calcified tissue international.
2001 Mar; 68(3):185-91. doi:
10.1007/s002230001216. [PMID: 11351503] - C H Woo, Y W Eom, M H Yoo, H J You, H J Han, W K Song, Y J Yoo, J S Chun, J H Kim. Tumor necrosis factor-alpha generates reactive oxygen species via a cytosolic phospholipase A2-linked cascade.
The Journal of biological chemistry.
2000 Oct; 275(41):32357-62. doi:
10.1074/jbc.m005638200. [PMID: 10934206] - Y Kohjimoto, T W Honeyman, J Jonassen, K Gravel, L Kennington, C R Scheid. Phospholipase A2 mediates immediate early genes in cultured renal epithelial cells: possible role of lysophospholipid.
Kidney international.
2000 Aug; 58(2):638-46. doi:
10.1046/j.1523-1755.2000.00210.x. [PMID: 10916087] - S S Kang, T Li, D Xu, P S Reinach, L Lu. Inhibitory effect of PGE2 on EGF-induced MAP kinase activity and rabbit corneal epithelial proliferation.
Investigative ophthalmology & visual science.
2000 Jul; 41(8):2164-9. doi:
. [PMID: 10892858] - H J Han, H J Choi, S H Park. High glucose-induced inhibition of alpha-methyl-D-glucopyranoside uptake is mediated by protein kinase C-dependent activation of arachidonic acid release in primary cultured rabbit renal proximal tubule cells.
Journal of cellular physiology.
2000 Jun; 183(3):355-63. doi:
10.1002/(sici)1097-4652(200006)183:3<355::aid-jcp8>3.0.co;2-y. [PMID: 10797310] - M Liang, F G Knox. Nitric oxide activates PKCalpha and inhibits Na+-K+-ATPase in opossum kidney cells.
The American journal of physiology.
1999 12; 277(6):F859-65. doi:
10.1152/ajprenal.1999.277.6.f859. [PMID: 10600932] - Y Kohjimoto, L Kennington, C R Scheid, T W Honeyman. Role of phospholipase A2 in the cytotoxic effects of oxalate in cultured renal epithelial cells.
Kidney international.
1999 Oct; 56(4):1432-41. doi:
10.1046/j.1523-1755.1999.00683.x. [PMID: 10504495] - T Almeida, R A Cunha, J A Ribeiro. Facilitation by arachidonic acid of acetylcholine release from the rat hippocampus.
Brain research.
1999 Apr; 826(1):104-11. doi:
10.1016/s0006-8993(99)01267-6. [PMID: 10216201] - M Dadaian, P Westlund. Eicosanoid metabolism in human platelets is modified by albumin.
Advances in experimental medicine and biology.
1999; 469(?):23-7. doi:
10.1007/978-1-4615-4793-8_4. [PMID: 10667305] - M A Lal, C R Kennedy, P R Proulx, R L Hébert. Bradykinin-stimulated cPLA2 phosphorylation is protein kinase C dependent in rabbit CCD cells.
The American journal of physiology.
1997 12; 273(6):F907-15. doi:
10.1152/ajprenal.1997.273.6.f907. [PMID: 9435679]
