7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-3-(thiadiazol-5-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (BioDeep_00000913139)

   


代谢物信息卡片


7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-3-(thiadiazol-5-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

化学式: C16H15N7O5S4 (513.0018)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)CSC4=CN=NS4)C(=O)O
InChI: InChI=1S/C16H15N7O5S4/c1-28-21-9(7-5-31-16(17)19-7)12(24)20-10-13(25)23-11(15(26)27)6(4-30-14(10)23)3-29-8-2-18-22-32-8/h2,5,10,14H,3-4H2,1H3,(H2,17,19)(H,20,24)(H,26,27)/b21-9-

描述信息

D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams

同义名列表

1 个代谢物同义名

7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-3-(thiadiazol-5-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid



数据库引用编号

1 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

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  • K Kono, S Takeda, I Tatara, K Arakawa. In vitro activities of arbekacin, alone and in combination, against methicillin-resistant Staphylococcus aureus. The Japanese journal of antibiotics. 1994 Jun; 47(6):710-9. doi: NULL. [PMID: 8072179]
  • Y Yasumoto, Y Kadota, K Kumami, M Miyajima, O Tsuji, H Nakano, K Matsumura. [Cefuzonam penetration into cerebrospinal fluid]. The Japanese journal of antibiotics. 1993 Jan; 46(1):36-43. doi: NULL. [PMID: 8455330]
  • S Tawara, S Matsumoto, Y Matsumoto, T Kamimura, S Goto. Structure-binding relationship and binding sites of cephalosporins in human serum albumin. The Journal of antibiotics. 1992 Aug; 45(8):1346-57. doi: 10.7164/antibiotics.45.1346. [PMID: 1399856]
  • H Nagasaka, T Miyazaki, H Naito. [Adsorption of other drugs by hemodialysis membrane]. Nihon rinsho. Japanese journal of clinical medicine. 1991 Dec; 49 Suppl(?):190-5. doi: NULL. [PMID: 1808254]
  • Y Inamoto, J Goto, K Sakane, T Kamimura, T Takaya. Studies on beta-lactam antibiotics. XIX. Structure-activity relationships of cephalosporins having a thiadiazolylthiomethyl group at the C-3 side chain. The Journal of antibiotics. 1991 May; 44(5):507-16. doi: 10.7164/antibiotics.44.507. [PMID: 2061194]
  • M Hirano, M Fujimura, A Yamamoto, I Yamamoto, K Nishimura, H Takahara, T Hirano, A Mori. [A clinical study in postoperative bile excretion of cefuzonam]. The Japanese journal of antibiotics. 1991 Jan; 44(1):9-13. doi: NULL. [PMID: 2041151]
  • S Arai, S Hayashi. Therapeutic effects of cefpirome (HR 810) on experimental mixed infections with Enterococcus faecalis and Escherichia coli in mice. Infection. 1990 May; 18(3):186-90. doi: 10.1007/bf01642112. [PMID: 2194972]
  • M Miyamoto, T Sudo, T Kuyama, M Kawamura. Assessment of antimicrobial penetration into the pancreatic juice in dogs. Nihon geka hokan. Archiv fur japanische Chirurgie. 1990 May; 59(3):205-10. doi: NULL. [PMID: 2130783]
  • I Sugihara, K Ueda, H Saiki, M Hanada, H Doi, T Ishibashi, M Nakayama, R Numa, K Yamauchi, R Kawata. [Comparison of intraocular penetration level of cefuzonam sodium and cefotiam after intravenous and subconjunctival injection]. Nippon Ganka Gakkai zasshi. 1990 Feb; 94(2):211-8. doi: NULL. [PMID: 2368649]
  • M Imaizumi, T Ojika, T Uchida, Y Uchida, M Sakakibara, D Kondo, T Abe. [A clinical study of pulmonary tissue uptake of cefuzonam and its use in prophylaxis of postoperative infections]. The Japanese journal of antibiotics. 1989 Nov; 42(11):2393-405. doi: NULL. [PMID: 2621781]
  • T Higami, K Ogawa, T Asada, M Chibana, N Mukohara, M Nishiwaki, N Yoshimura. [A clinical study on cefuzonam concentrations in myocardium in open heart surgery]. The Japanese journal of antibiotics. 1989 Sep; 42(9):1882-7. doi: NULL. [PMID: 2810751]
  • T Uete, K Matsuo. [Clinical laboratory approach for estimating effective administrative dose of cefuzonam. Evaluation of disc susceptibility test and its interpretation system]. The Japanese journal of antibiotics. 1988 Oct; 41(10):1407-17. doi: NULL. [PMID: 3204654]
  • M Hongo, R Shimizu, K Sakae, T Kohchi, M Tani. [Transfer of cefuzonam into female genital organs]. The Japanese journal of antibiotics. 1988 Aug; 41(8):997-1001. doi: NULL. [PMID: 3172470]
  • K Kubota, I Yasuhi, M Hirai, K Shimomura. [Pharmacokinetic, bacteriological and clinical studies of cefuzonam in the field of obstetrics and gynecology]. The Japanese journal of antibiotics. 1988 Aug; 41(8):1015-29. doi: NULL. [PMID: 3050187]
  • H Takaoka, S Makinoda, K Ichinoe, I Kawaguchi, M Nishiya. [Pharmacokinetic and clinical studies of cefuzonam in the field of obstetrics and gynecology]. The Japanese journal of antibiotics. 1988 Jan; 41(1):18-24. doi: NULL. [PMID: 3367511]
  • I Miyakawa, H Yamao, K Taniyama, K Kawano, Y Haruyama, N Mori. [Pharmacokinetics of cefuzonam in peripheral venous serum, uterine arterial serum and intrapelvic female organs]. The Japanese journal of antibiotics. 1987 May; 40(5):1089-93. doi: NULL. [PMID: 3669288]
  • T Yamamoto, J Yasuda, M Kanao, H Okada. [Fundamental and clinical studies on cefuzonam in the field of obstetrics and gynecology]. The Japanese journal of antibiotics. 1987 May; 40(5):1074-83. doi: NULL. [PMID: 3669286]
  • H Takamizawa, H Matsui, S Kobayashi, H Shimizu, K Kato, A Yamaga, K Yamasawa, S Suzuki. [Pharmacokinetic and clinical studies of cefuzonam in obstetric and gynecologic infections]. The Japanese journal of antibiotics. 1987 May; 40(5):1001-6. doi: NULL. [PMID: 3669279]
  • N Cho, K Fukunaga, K Kunii, T Kimura, S Kameda, H Watanabe. [Pharmacokinetic and clinical studies on cefuzonam in obstetrics and gynecology]. The Japanese journal of antibiotics. 1987 May; 40(5):1007-28. doi: NULL. [PMID: 3669280]
  • Y Toyonaga, M Sugita, K Kawamura, K Seo, T Takahashi, M Hori. [Fundamental and clinical studies on cefuzoname in the pediatric field]. The Japanese journal of antibiotics. 1987 Apr; 40(4):843-65. doi: . [PMID: 3613094]
  • S Fukuda, Y Yoshida, T Yanagi, Y Tsuji. [Studies on cefuzoname in the field of pediatrics]. The Japanese journal of antibiotics. 1987 Apr; 40(4):901-6. doi: NULL. [PMID: 3613097]
  • T Motohiro, T Koga, Y Shimada, S Tomita, T Fujimoto, T Nishiyama, K Tominaga, F Yamashita, N Takajo, M Nakano. [Pharmacokinetic and clinical studies of cefuzoname in the pediatric field]. The Japanese journal of antibiotics. 1987 Apr; 40(4):883-900. doi: NULL. [PMID: 3613096]
  • H Ogura, T Tomoda, F Hamada, M Fujieda, Y Ohara, K Araki, I Kitamura. [Cefuzonam, a new cephem antibiotic in the field of pediatrics. Concentrations in serum and clinical efficacy]. The Japanese journal of antibiotics. 1987 Mar; 40(3):680-4. doi: NULL. [PMID: 3613087]
  • S Nakazawa, H Sato, A Narita, K Matsumoto, H Suzuki, S Nakazawa, H Chikaoka, R Koido, M Kamigaki, Y Nakada. [Evaluation of cefuzonam in the pediatric field]. The Japanese journal of antibiotics. 1987 Mar; 40(3):613-29. doi: NULL. [PMID: 3613082]
  • H Meguro, O Arimasu, H Shiraishi, M Kobayashi, R Fuji, J Mashiko. [Clinical and pharmacokinetic evaluations of cefuzonam in children]. The Japanese journal of antibiotics. 1987 Mar; 40(3):630-40. doi: NULL. [PMID: 3613083]
  • N Iwai, M Miyazu, M Shibata, H Nakamura, M Katayama, Y Taneda, K Inokuma. [Pharmacokinetic and clinical studies of cefuzonam in pediatrics]. The Japanese journal of antibiotics. 1987 Mar; 40(3):641-57. doi: NULL. [PMID: 3613084]
  • T Hosoda, M Masuda, M Miyao, I Honda. [Clinical experience with cefuzonam in bacterial infection of children]. The Japanese journal of antibiotics. 1987 Feb; 40(2):449-59. doi: NULL. [PMID: 3599393]
  • K Kuno, S Hakamada, Y Miyachi, T Nakashima, F Hayakawa, K Miura, Y Miyajima. [Fundamental and clinical studies on cefuzonam in the field of pediatrics]. The Japanese journal of antibiotics. 1987 Feb; 40(2):405-18. doi: NULL. [PMID: 3599389]
  • K Sunakawa, Y Ishizuka, N Kawai, N Saito. [Fundamental and clinical studies of cefuzonam in pediatrics]. The Japanese journal of antibiotics. 1987 Feb; 40(2):385-95. doi: NULL. [PMID: 3599387]
  • T Nishimura, K Tabuki, T Takashima, M Takagi. [Laboratory and clinical studies of cefuzonam in pediatric field]. The Japanese journal of antibiotics. 1987 Feb; 40(2):427-38. doi: NULL. [PMID: 3599391]
  • Y Goto, K Kida, H Matsuda, M Murase. [Clinical studies of cefuzonam in the pediatric field]. The Japanese journal of antibiotics. 1987 Feb; 40(2):419-25. doi: NULL. [PMID: 3599390]
  • R Fujii, H Meguro, O Arimasu, J Mashiko, M Kobayashi, S Nakazawa, H Satoh, A Narita, K Matsumoto, H Suzuki. [Pharmacokinetic and clinical studies on cefuzonam in the pediatric field]. The Japanese journal of antibiotics. 1986 Oct; 39(10):2601-19. doi: NULL. [PMID: 3806949]
  • T Haruta, H Yamamoto, K E Okura, S Kuroki, Y Kobayashi. Penetration of cefuzoname into the cerebrospinal fluid of rabbits. Antimicrobial agents and chemotherapy. 1986 Jul; 30(1):157-60. doi: 10.1128/aac.30.1.157. [PMID: 3530123]