Diterpene alkaloid (BioDeep_00000913093)
代谢物信息卡片
Diterpene alkaloid
化学式: C24H39NO4 (405.28789340000003)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1C2C(CCC1=CC(=O)OCCN(C)C)C3(CCC(C(C3CC2=O)(C)C)O)C
InChI: InChI=1S/C24H39NO4/c1-15-16(13-21(28)29-12-11-25(5)6)7-8-17-22(15)18(26)14-19-23(2,3)20(27)9-10-24(17,19)4/h13,15,17,19-20,22,27H,7-12,14H2,1-6H3/b16-13-
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Arash Salehi, Behzad Zolfaghari, Mahmoud Aghaei, Hajar Sirous, Morteza Sadeghi, Mohammad Reza Gholami, Parham Reisi, Mustafa Ghanadian. New amide and diterpene alkaloids with anticholinesterase activity from Delphinium cyphoplectrum roots.
Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences.
2024 Jun; 32(1):237-251. doi:
10.1007/s40199-024-00509-y. [PMID: 38498253] - Zejun Liu, Xiaoli Li, Qi Luo, Hong Pan, Fuguo Shi. Structural feature-based strategy for the identification of diterpene alkaloids in Aconitum carmichaeli Debeaux.
Fitoterapia.
2024 Jan; 172(?):105761. doi:
10.1016/j.fitote.2023.105761. [PMID: 38036079] - Quynh N Quach, Keith Clay, Stephen T Lee, Dale R Gardner, Daniel Cook. Phylogenetic patterns of bioactive secondary metabolites produced by fungal endosymbionts in morning glories (Ipomoeeae, Convolvulaceae).
The New phytologist.
2023 05; 238(4):1351-1361. doi:
10.1111/nph.18785. [PMID: 36727281] - Qiang Ye, Hongmei Liu, Chengxin Fang, Yushi Liu, Xiaomei Liu, Juanru Liu, Cunyan Zhang, Tingmo Zhang, Cheng Peng, Li Guo. Cardiotoxicity evaluation and comparison of diterpene alkaloids on zebrafish.
Drug and chemical toxicology.
2021 May; 44(3):294-301. doi:
10.1080/01480545.2019.1586916. [PMID: 30895830] - Zhi-Hui Luo, Yang Chen, Xin-Yi Sun, Hua Fan, Wei Li, Liang Deng, Tian-Peng Yin. A new diterpenoid alkaloid from Aconitum hemsleyanum.
Natural product research.
2020 May; 34(9):1331-1336. doi:
10.1080/14786419.2018.1560292. [PMID: 30663368] - Li-Ping Dai, Xiao-Fei Li, Qing-Mei Feng, Ling-Xia Zhang, Qiu-Yan Liu, Er-Ping Xu, Hong Wu, Zhi-Min Wang. Isolation and identification of two pairs of cytotoxic diterpene tautomers and their tautomerization mechanisms.
Scientific reports.
2020 01; 10(1):1442. doi:
10.1038/s41598-020-58260-8. [PMID: 31996737] - Dan He, Wang-Yan Liu, Jiao Xiong, Jun-Ju Xu, Yong Shen. Four new C19-diterpenoid alkaloids from Aconitum hemsleyanum var. circinatum.
Journal of Asian natural products research.
2019 Sep; 21(9):833-841. doi:
10.1080/10286020.2018.1500555. [PMID: 30417650] - Liang Lei, Weiguang Sun, Long He, Hongfeng Jiang, Mingjin Zhang, Wenjuan He, Zhengxi Hu, Ye Gu, Hongping Song, Yonghui Zhang. Cardiotoxicity of Consolida rugulosa, a poisonous weed in Western China.
Ecotoxicology and environmental safety.
2019 Apr; 170(?):141-147. doi:
10.1016/j.ecoenv.2018.11.109. [PMID: 30529612] - Lu-Lin Xu, Ping Hai, Shuai-Bing Zhang, Jing-Fang Xiao, Yuan Gao, Bing-Ji Ma, Hai-Yan Fu, Ye-Miao Chen, Xiao-Long Yang. Prenylated Indole Diterpene Alkaloids from a Mine-Soil-Derived Tolypocladium sp.
Journal of natural products.
2019 02; 82(2):221-231. doi:
10.1021/acs.jnatprod.8b00589. [PMID: 30702286] - Ke Zan, Ci-Ren Wangjie, Jing Lu, Li-Nong Guo, Jian Zheng, Shuang-Cheng Ma. [Content determination of four diester diterpenoid alkaloids in leaves of Aconitum kusnezoffii by HPLC].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2018 Feb; 43(4):766-771. doi:
10.19540/j.cnki.cjcmm.2018.0019. [PMID: 29600653] - Filippo Fratini, Giovanni Cilia, Barbara Turchi, Antonio Felicioli. Insects, arachnids and centipedes venom: A powerful weapon against bacteria. A literature review.
Toxicon : official journal of the International Society on Toxinology.
2017 May; 130(?):91-103. doi:
10.1016/j.toxicon.2017.02.020. [PMID: 28242227] - Fu-Li Wen, Ying-Ying Jiang, Hua Tang, Dong-Lin Chen, Feng-Peng Wang. Two New C19-Diterpenoid Alkaloids from Aconitum nagarum var. lasiandrum.
Natural product communications.
2017 Mar; 12(3):329-330. doi:
". [PMID: 30549877] - Chengjin Li, Byeong Uk Ji, Ji Eun Lee, Min Young Park, Sungchul Kim, Seung Tae Kim, Sungtae Koo. Inhibitory Effects of Scolopendra Pharmacopuncture on the Development and Maintenance of Neuropathic Pain in Rats: Possible Involvement of Spinal Glial Cells.
Journal of acupuncture and meridian studies.
2015 Oct; 8(5):236-44. doi:
10.1016/j.jams.2015.01.001. [PMID: 26433800] - Mei Wang, Emily J Carrell, Zulfiqar Ali, Bharathi Avula, Cristina Avonto, Jon F Parcher, Ikhlas A Khan. Comparison of three chromatographic techniques for the detection of mitragynine and other indole and oxindole alkaloids in Mitragyna speciosa (kratom) plants.
Journal of separation science.
2014 Jun; 37(12):1411-8. doi:
10.1002/jssc.201301389. [PMID: 24659356] - Minzhi Chen, Jing Li, Fan Zhang, Zhonghua Liu. Isolation and characterization of SsmTx-I, a Specific Kv2.1 blocker from the venom of the centipede Scolopendra Subspinipes Mutilans L. Koch.
Journal of peptide science : an official publication of the European Peptide Society.
2014 Mar; 20(3):159-64. doi:
10.1002/psc.2588. [PMID: 24464516] - MuDan Cai, Sun-Mi Choi, Bong Keun Song, Ilhong Son, Sungchul Kim, Eun Jin Yang. Scolopendra subspinipes mutilans attenuates neuroinflammation in symptomatic hSOD1(G93A) mice.
Journal of neuroinflammation.
2013 Oct; 10(?):131. doi:
10.1186/1742-2094-10-131. [PMID: 24168240] - Haixia Zhao, Ying Li, Yuzhong Wang, Jing Zhang, Xiaoming Ouyang, Renxiu Peng, Jing Yang. Antitumor and immunostimulatory activity of a polysaccharide-protein complex from Scolopendra subspinipes mutilans L. Koch in tumor-bearing mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2012 Aug; 50(8):2648-55. doi:
10.1016/j.fct.2012.05.018. [PMID: 22613217] - Duan-Yong Liu, Hai-Mei Zhao, Shao-Min Cheng, Yi Rao, Xiao-Ying Huang, Zhi-Qin Zuo, Meng Lei, Yong-Mei Guan, Hong-Ning Liu, Ai-Ping Lu. Scorpio and Scolopendra attenuate inflammation and articular damage in rats with collagen-induced arthritis.
Journal of ethnopharmacology.
2012 Jun; 141(2):603-7. doi:
10.1016/j.jep.2011.08.056. [PMID: 21911049] - Duan-Yong Liu, Hai-Mei Zhao, Xiao-Ying Huang, Zhi-Qin Zuo, Yan-Hui Wang, Shao-Min Cheng. [Regulation effect of scorpio and scolopendra on CD4 + CD25 + FoxP3 + Treg cell in peripheral blood from rats with collagen-induced arthritis (CIA)].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2012 Apr; 35(4):525-8. doi:
NULL. [PMID: 23019895] - Hai-Mei Zhao, Zhi-Qin Zuo, Shao-Min Cheng. [Effects of scorpion and centipede on IL-2, IL-4, and IL-10 in the small intestinal mucosa and joint injury of rats with collagen induced arthritis].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2012 Jan; 32(1):80-3. doi:
". [PMID: 22500400] - Qing-Fa Tang, Chun-Hua Yang, Jing-Han Liu, Wen-Cai Ye, Shou-Xun Zhao, Yang Lü, Li Mao, Qi-Tai Zheng. [A new hetisine-type alkaloid from the stems and leaves of Aconitum coreanum].
Yao xue xue bao = Acta pharmaceutica Sinica.
2005 Jul; 40(7):640-3. doi:
. [PMID: 16196272] - Geoffrey C Kite, Muna Ismail, Monique S J Simmonds, Peter J Houghton. Use of doubly protonated molecules in the analysis of cathedulins in crude extracts of khat (Catha edulis) by liquid chromatography/serial mass spectrometry.
Rapid communications in mass spectrometry : RCM.
2003; 17(14):1553-64. doi:
10.1002/rcm.1085. [PMID: 12845580] - K Watanabe, S Yano, S Horie, L T Yamamoto. Inhibitory effect of mitragynine, an alkaloid with analgesic effect from Thai medicinal plant Mitragyna speciosa, on electrically stimulated contraction of isolated guinea-pig ileum through the opioid receptor.
Life sciences.
1997; 60(12):933-42. doi:
10.1016/s0024-3205(97)00023-4. [PMID: 9061050] - L Crombie. The cathedulin alkaloids.
Bulletin on narcotics.
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