4-Amino-1-{5-O-[hydroxy({hydroxy[2-(trimethylazaniumyl)ethoxy]phosphoryl}oxy)phosphoryl]pentofuranosyl}pyrimidin-2(1H)-one (BioDeep_00000912473)
代谢物信息卡片
4-Amino-1-{5-O-[hydroxy({hydroxy[2-(trimethylazaniumyl)ethoxy]phosphoryl}oxy)phosphoryl]pentofuranosyl}pyrimidin-2(1H)-one
化学式: C14H27N4O11P2+ (489.11515119999996)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C[N+](C)(C)CCOP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=CC(=NC2=O)N)O)O
InChI: InChI=1S/C14H26N4O11P2/c1-18(2,3)6-7-26-30(22,23)29-31(24,25)27-8-9-11(19)12(20)13(28-9)17-5-4-10(15)16-14(17)21/h4-5,9,11-13,19-20H,6-8H2,1-3H3,(H3-,15,16,21,22,23,24,25)/p+1
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Nichola Z Lax, Ilse S Pienaar, Amy K Reeve, Philippa D Hepplewhite, Evelyn Jaros, Robert W Taylor, Raj N Kalaria, Doug M Turnbull. Microangiopathy in the cerebellum of patients with mitochondrial DNA disease.
Brain : a journal of neurology.
2012 Jun; 135(Pt 6):1736-50. doi:
10.1093/brain/aws110. [PMID: 22577219] - Azza Al-Tawashi, Sung Yun Jung, Dou Liu, Bing Su, Jun Qin. Protein implicated in nonsyndromic mental retardation regulates protein kinase A (PKA) activity.
The Journal of biological chemistry.
2012 Apr; 287(18):14644-58. doi:
10.1074/jbc.m111.261875. [PMID: 22375002] - Raveen Parboosing, Glenn E M Maguire, Patrick Govender, Hendrik G Kruger. Nanotechnology and the treatment of HIV infection.
Viruses.
2012 04; 4(4):488-520. doi:
10.3390/v4040488. [PMID: 22590683] - Ainiwaer Aikemu, Abdiryim Yusup, Anwar Umar, Bénédicte Berké, Nicholas Moore, Halmurat Upur. The impact of the Uighur medicine abnormal savda munziq on antitumor and antioxidant activity in a S180 and Ehrlich ascites carcinoma mouse tumor model.
Pharmacognosy magazine.
2012 Apr; 8(30):141-8. doi:
10.4103/0973-1296.96568. [PMID: 22701288] - Shinichi Takahashi, Yoshikane Izawa, Norihiro Suzuki. Astroglial pentose phosphate pathway rates in response to high-glucose environments.
ASN neuro.
2012 Mar; 4(2):. doi:
10.1042/an20120002. [PMID: 22300409] - Daniel A Rossignol. Hyperbaric oxygen treatment for inflammatory bowel disease: a systematic review and analysis.
Medical gas research.
2012 Mar; 2(1):6. doi:
10.1186/2045-9912-2-6. [PMID: 22417628] - D Ehrlich, M Pirchl, C Humpel. Effects of long-term moderate ethanol and cholesterol on cognition, cholinergic neurons, inflammation, and vascular impairment in rats.
Neuroscience.
2012 Mar; 205(?):154-66. doi:
10.1016/j.neuroscience.2011.12.054. [PMID: 22244974] - Zhen Haining, Nobuyuki Kawai, Keisuke Miyake, Masaki Okada, Shuichi Okubo, Xiang Zhang, Zhou Fei, Takashi Tamiya. Relation of LAT1/4F2hc expression with pathological grade, proliferation and angiogenesis in human gliomas.
BMC clinical pathology.
2012 Feb; 12(?):4. doi:
10.1186/1472-6890-12-4. [PMID: 22373026] - Paulien Gm Ravenstijn, Henk-Jan Drenth, Michael J O'Neill, Meindert Danhof, Elizabeth Cm de Lange. Evaluation of blood-brain barrier transport and CNS drug metabolism in diseased and control brain after intravenous L-DOPA in a unilateral rat model of Parkinson's disease.
Fluids and barriers of the CNS.
2012 Feb; 9(?):4. doi:
10.1186/2045-8118-9-4. [PMID: 22316420] - Marie-Françoise Ritz, Caspar Grond-Ginsbach, Stefan Engelter, Philippe Lyrer. Gene expression suggests spontaneously hypertensive rats may have altered metabolism and reduced hypoxic tolerance.
Current neurovascular research.
2012 Feb; 9(1):10-9. doi:
10.2174/156720212799297074. [PMID: 22272763] - Qiang Wang, Feng Wang, Xin Li, Qianzi Yang, Xuying Li, Ning Xu, Yi Huang, Qiaomei Zhang, Xingchun Gou, Shaoyang Chen, Lize Xiong. Electroacupuncture pretreatment attenuates cerebral ischemic injury through α7 nicotinic acetylcholine receptor-mediated inhibition of high-mobility group box 1 release in rats.
Journal of neuroinflammation.
2012 Jan; 9(?):24. doi:
10.1186/1742-2094-9-24. [PMID: 22277256] - Dominik Michalski, Carsten Hobohm, Christopher Weise, Johann Pelz, Marita Heindl, Manja Kamprad, Johannes Kacza, Wolfgang Härtig. Interrelations between blood-brain barrier permeability and matrix metalloproteinases are differently affected by tissue plasminogen activator and hyperoxia in a rat model of embolic stroke.
Medical gas research.
2012 Jan; 2(1):2. doi:
10.1186/2045-9912-2-2. [PMID: 22273146] - Marina Quartu, Maria P Serra, Marianna Boi, Giuliano Pillolla, Tiziana Melis, Laura Poddighe, Marina Del Fiacco, Danilo Falconieri, Gianfranca Carta, Elisabetta Murru, Lina Cordeddu, Antonio Piras, Maria Collu, Sebastiano Banni. Effect of acute administration of Pistacia lentiscus L. essential oil on rat cerebral cortex following transient bilateral common carotid artery occlusion.
Lipids in health and disease.
2012 Jan; 11(?):8. doi:
10.1186/1476-511x-11-8. [PMID: 22239952] - Jonathan Bertin, Corinne Barat, Sylvie Méthot, Michel J Tremblay. Interactions between prostaglandins, leukotrienes and HIV-1: possible implications for the central nervous system.
Retrovirology.
2012 Jan; 9(?):4. doi:
10.1186/1742-4690-9-4. [PMID: 22236409] - Natasha F Homji, Xin Mao, Erik F Langsdorf, Sulie L Chang. Endotoxin-induced cytokine and chemokine expression in the HIV-1 transgenic rat.
Journal of neuroinflammation.
2012 Jan; 9(?):3. doi:
10.1186/1742-2094-9-3. [PMID: 22216977] - LinLin Tian, Morvarid Karimi, Susan K Loftin, Chris A Brown, HuChuan Xia, JinBin Xu, Robert H Mach, Joel S Perlmutter. No differential regulation of dopamine transporter (DAT) and vesicular monoamine transporter 2 (VMAT2) binding in a primate model of Parkinson disease.
PloS one.
2012; 7(2):e31439. doi:
10.1371/journal.pone.0031439. [PMID: 22359591] - Galina Dvoriantchikova, Dmitry Ivanov, David Barakat, Alexander Grinberg, Rong Wen, Vladlen Z Slepak, Valery I Shestopalov. Genetic ablation of Pannexin1 protects retinal neurons from ischemic injury.
PloS one.
2012; 7(2):e31991. doi:
10.1371/journal.pone.0031991. [PMID: 22384122] - Elisa Mitiko Kawamoto, Carmen Vivar, Simonetta Camandola. Physiology and pathology of calcium signaling in the brain.
Frontiers in pharmacology.
2012; 3(?):61. doi:
10.3389/fphar.2012.00061. [PMID: 22518105] - Di Yang, Suk-Yee Li, Chung-Man Yeung, Raymond Chuen-Chung Chang, Kwok-Fai So, David Wong, Amy C Y Lo. Lycium barbarum extracts protect the brain from blood-brain barrier disruption and cerebral edema in experimental stroke.
PloS one.
2012; 7(3):e33596. doi:
10.1371/journal.pone.0033596. [PMID: 22438957] - Sylvia Wagner, Anja Zensi, Sascha L Wien, Sabrina E Tschickardt, Wladislaw Maier, Tikva Vogel, Franz Worek, Claus U Pietrzik, Jörg Kreuter, Hagen von Briesen. Uptake mechanism of ApoE-modified nanoparticles on brain capillary endothelial cells as a blood-brain barrier model.
PloS one.
2012; 7(3):e32568. doi:
10.1371/journal.pone.0032568. [PMID: 22396775] - W Gordon Frankle, Raymond Y Cho, N Scott Mason, Chi-Min Chen, Michael Himes, Christopher Walker, David A Lewis, Chester A Mathis, Rajesh Narendran. [11C]flumazenil binding is increased in a dose-dependent manner with tiagabine-induced elevations in GABA levels.
PloS one.
2012; 7(2):e32443. doi:
10.1371/journal.pone.0032443. [PMID: 22384252] - Masanori Tachikawa, Saori Ikeda, Jun Fujinawa, Shirou Hirose, Shin-ichi Akanuma, Ken-ichi Hosoya. γ-Aminobutyric acid transporter 2 mediates the hepatic uptake of guanidinoacetate, the creatine biosynthetic precursor, in rats.
PloS one.
2012; 7(2):e32557. doi:
10.1371/journal.pone.0032557. [PMID: 22384273] - Lena A Basile, Dolph Ellefson, Zoya Gluzman-Poltorak, Katiana Junes-Gill, Vernon Mar, Sarita Mendonca, Joseph D Miller, Jamie Tom, Alice Trinh, Timothy K Gallaher. HemaMax™, a recombinant human interleukin-12, is a potent mitigator of acute radiation injury in mice and non-human primates.
PloS one.
2012; 7(2):e30434. doi:
10.1371/journal.pone.0030434. [PMID: 22383962] - Jung Pyo Lee, Seung Hee Yang, Hee-Yoon Lee, Bora Kim, Joo-Youn Cho, Jin Ho Paik, Yun Jung Oh, Dong Ki Kim, Chun Soo Lim, Yon Su Kim. Soluble epoxide hydrolase activity determines the severity of ischemia-reperfusion injury in kidney.
PloS one.
2012; 7(5):e37075. doi:
10.1371/journal.pone.0037075. [PMID: 22590647] - Emmanuelle Vidal-Petiot, Lydie Cheval, Julie Faugeroux, Thierry Malard, Alain Doucet, Xavier Jeunemaitre, Juliette Hadchouel. A new methodology for quantification of alternatively spliced exons reveals a highly tissue-specific expression pattern of WNK1 isoforms.
PloS one.
2012; 7(5):e37751. doi:
10.1371/journal.pone.0037751. [PMID: 22701532] - Dvora Rubinger, Rebecca Backenroth, Dan Sapoznikov. Sympathetic activation and baroreflex function during intradialytic hypertensive episodes.
PloS one.
2012; 7(5):e36943. doi:
10.1371/journal.pone.0036943. [PMID: 22629345] - Amutha Selvamani, Pratheesh Sathyan, Rajesh C Miranda, Farida Sohrabji. An antagomir to microRNA Let7f promotes neuroprotection in an ischemic stroke model.
PloS one.
2012; 7(2):e32662. doi:
10.1371/journal.pone.0032662. [PMID: 22393433] - Pengwei Zhuang, Yanjun Zhang, Guangzhi Cui, Yuhong Bian, Mixia Zhang, Jinbao Zhang, Yang Liu, Xinpeng Yang, Adejobi Oluwaniyi Isaiah, Yingxue Lin, Yongbo Jiang. Direct stimulation of adult neural stem/progenitor cells in vitro and neurogenesis in vivo by salvianolic acid B.
PloS one.
2012; 7(4):e35636. doi:
10.1371/journal.pone.0035636. [PMID: 22545124] - Stanislav I Svetlov, Victor Prima, Olena Glushakova, Artem Svetlov, Daniel R Kirk, Hector Gutierrez, Victor L Serebruany, Kenneth C Curley, Kevin K W Wang, Ronald L Hayes. Neuro-glial and systemic mechanisms of pathological responses in rat models of primary blast overpressure compared to 'composite' blast.
Frontiers in neurology.
2012; 3(?):15. doi:
10.3389/fneur.2012.00015. [PMID: 22403567] - Peter F Mount, Kurt Gleich, Shanna Tam, Scott A Fraser, Suet-Wan Choy, Karen M Dwyer, Bo Lu, Bryce Van Denderen, Günter Fingerle-Rowson, Richard Bucala, Bruce E Kemp, David A Power. The outcome of renal ischemia-reperfusion injury is unchanged in AMPK-β1 deficient mice.
PloS one.
2012; 7(1):e29887. doi:
10.1371/journal.pone.0029887. [PMID: 22253816] - Kazunori Takahashi, Hiroki Mizukami, Kosuke Kamata, Wataru Inaba, Noriaki Kato, Chihiro Hibi, Soroku Yagihashi. Amelioration of acute kidney injury in lipopolysaccharide-induced systemic inflammatory response syndrome by an aldose reductase inhibitor, fidarestat.
PloS one.
2012; 7(1):e30134. doi:
10.1371/journal.pone.0030134. [PMID: 22253906] - Mallikarjunarao Kasam, Bing Yang, Roger Strong, Krystal Schaar, Vivek Misra, Xiaopei Xi, James C Grotta, Jaroslaw Aronowski, Sean I Savitz. Nitric oxide facilitates delivery and mediates improved outcome of autologous bone marrow mononuclear cells in a rodent stroke model.
PloS one.
2012; 7(3):e32793. doi:
10.1371/journal.pone.0032793. [PMID: 22412926] - Kimberley E Wever, Theo P Menting, Maroeska Rovers, J Adam van der Vliet, Gerard A Rongen, Rosalinde Masereeuw, Merel Ritskes-Hoitinga, Carlijn R Hooijmans, Michiel Warlé. Ischemic preconditioning in the animal kidney, a systematic review and meta-analysis.
PloS one.
2012; 7(2):e32296. doi:
10.1371/journal.pone.0032296. [PMID: 22389693] - Lu Ching-Hsiang, Hwang Chiao-Wen, Chen Nan-Fu, Liu Wen-Sheng, Hsiao Ya-Fen, Wu Wen-Tung. In vivo effects of Ginkgo biloba extract on interleukin-6 cytokine levels in patients with neurological disorders.
Indian journal of pharmacology.
2012 Jan; 44(1):118-21. doi:
10.4103/0253-7613.91881. [PMID: 22345884] - U R Goonetilleke, M Scarborough, S A Ward, S Hussain, A Kadioglu, S B Gordon. Death is associated with complement C3 depletion in cerebrospinal fluid of patients with pneumococcal meningitis.
mBio.
2012; 3(2):. doi:
10.1128/mbio.00272-11. [PMID: 22415003] - Silvia Gazzin, Nathalie Strazielle, Claudio Tiribelli, Jean-François Ghersi-Egea. Transport and metabolism at blood-brain interfaces and in neural cells: relevance to bilirubin-induced encephalopathy.
Frontiers in pharmacology.
2012; 3(?):89. doi:
10.3389/fphar.2012.00089. [PMID: 22629246] - George Füst, Lea Munthe-Fog, Zsolt Illes, Gábor Széplaki, Tihamér Molnar, Gabriella Pusch, Kristóf Hirschberg, Robert Szegedi, Zoltán Széplaki, Zoltán Prohászka, Mikkel-Ole Skjoedt, Peter Garred. Low ficolin-3 levels in early follow-up serum samples are associated with the severity and unfavorable outcome of acute ischemic stroke.
Journal of neuroinflammation.
2011 Dec; 8(?):185. doi:
10.1186/1742-2094-8-185. [PMID: 22206485] - Xiaoen Wang, Liang Zhang, S Nahum Goldberg, Manoj Bhasin, Victoria Brown, David C Alsop, Sabina Signoretti, James W Mier, Michael B Atkins, Rupal S Bhatt. High dose intermittent sorafenib shows improved efficacy over conventional continuous dose in renal cell carcinoma.
Journal of translational medicine.
2011 Dec; 9(?):220. doi:
10.1186/1479-5876-9-220. [PMID: 22188900] - Jaehyun Kim, Yongwook Jung. Different expressions of AQP1, AQP4, eNOS, and VEGF proteins in ischemic versus non-ischemic cerebropathy in rats: potential roles of AQP1 and eNOS in hydrocephalic and vasogenic edema formation.
Anatomy & cell biology.
2011 Dec; 44(4):295-303. doi:
10.5115/acb.2011.44.4.295. [PMID: 22254158] - Shinya Dohgu, Melissa A Fleegal-DeMotta, William A Banks. Lipopolysaccharide-enhanced transcellular transport of HIV-1 across the blood-brain barrier is mediated by luminal microvessel IL-6 and GM-CSF.
Journal of neuroinflammation.
2011 Nov; 8(?):167. doi:
10.1186/1742-2094-8-167. [PMID: 22129063] - Adám Dénes, Szilamér Ferenczi, Krisztina J Kovács. Systemic inflammatory challenges compromise survival after experimental stroke via augmenting brain inflammation, blood- brain barrier damage and brain oedema independently of infarct size.
Journal of neuroinflammation.
2011 Nov; 8(?):164. doi:
10.1186/1742-2094-8-164. [PMID: 22114895] - Andrea Mayado, Elisa Torres, Maria D Gutierrez-Lopez, Maria I Colado, Esther O'Shea. Increased interleukin-1β levels following low dose MDMA induces tolerance against the 5-HT neurotoxicity produced by challenge MDMA.
Journal of neuroinflammation.
2011 Nov; 8(?):165. doi:
10.1186/1742-2094-8-165. [PMID: 22114930] - Shruti Agnihotri, Alexandra Czap, Ilene Staff, Gil Fortunato, Louise D McCullough. Peripheral leukocyte counts and outcomes after intracerebral hemorrhage.
Journal of neuroinflammation.
2011 Nov; 8(?):160. doi:
10.1186/1742-2094-8-160. [PMID: 22087759] - Runkuan Yang, Shutian Zhang, Henri Kajander, Shengtao Zhu, Marja-Leena Koskinen, Jyrki Tenhunen. Ringer's lactate improves liver recovery in a murine model of acetaminophen toxicity.
BMC gastroenterology.
2011 Nov; 11(?):125. doi:
10.1186/1471-230x-11-125. [PMID: 22085740] - Masaya Miwa, Mizuki Tsuboi, Yumiko Noguchi, Aoi Enokishima, Toshitaka Nabeshima, Masayuki Hiramatsu. Effects of betaine on lipopolysaccharide-induced memory impairment in mice and the involvement of GABA transporter 2.
Journal of neuroinflammation.
2011 Nov; 8(?):153. doi:
10.1186/1742-2094-8-153. [PMID: 22053950] - Yuan-Hsiung Tsai, Li-Ming Hsu, Hsu-Huei Weng, Ming-Hsueh Lee, Jen-Tsung Yang, Ching-Po Lin. Voxel-based analysis of apparent diffusion coefficient in perihaematomal oedema: associated factors and outcome predictive value for intracerebral haemorrhage.
BMJ open.
2011 Nov; 1(1):e000230. doi:
10.1136/bmjopen-2011-000230. [PMID: 22080527] - Huong T Le, Aaron C Hirko, Jeffrey S Thinschmidt, Maria Grant, Zhimin Li, Joanna Peris, Michael A King, Jeffrey A Hughes, Sihong Song. The protective effects of plasma gelsolin on stroke outcome in rats.
Experimental & translational stroke medicine.
2011 Nov; 3(1):13. doi:
10.1186/2040-7378-3-13. [PMID: 22047744] - N D Volkow, G-J Wang, J H Newcorn, S H Kollins, T L Wigal, F Telang, J S Fowler, R Z Goldstein, N Klein, J Logan, C Wong, J M Swanson. Motivation deficit in ADHD is associated with dysfunction of the dopamine reward pathway.
Molecular psychiatry.
2011 Nov; 16(11):1147-54. doi:
10.1038/mp.2010.97. [PMID: 20856250] - Friederike Pfeiffer, Julia Schäfer, Ruth Lyck, Victoria Makrides, Sarah Brunner, Nicole Schaeren-Wiemers, Urban Deutsch, Britta Engelhardt. Claudin-1 induced sealing of blood-brain barrier tight junctions ameliorates chronic experimental autoimmune encephalomyelitis.
Acta neuropathologica.
2011 Nov; 122(5):601-14. doi:
10.1007/s00401-011-0883-2. [PMID: 21983942] - Sun Mi Park, Jin Hee Shin, Gyeong Joon Moon, Sung Ig Cho, Yong Beom Lee, Byoung Joo Gwag. Effects of collagen-induced rheumatoid arthritis on amyloidosis and microvascular pathology in APP/PS1 mice.
BMC neuroscience.
2011 Oct; 12(?):106. doi:
10.1186/1471-2202-12-106. [PMID: 22029666] - Chun-chao Han, Hong Wei, Jianyou Guo. Anti-inflammatory effects of fermented and non-fermented Sophora flavescens: a comparative study.
BMC complementary and alternative medicine.
2011 Oct; 11(?):100. doi:
10.1186/1472-6882-11-100. [PMID: 22026927] - Anat Elmann, Sharon Mordechay, Hilla Erlank, Alona Telerman, Miriam Rindner, Rivka Ofir. Anti-neuroinflammatory effects of the extract of Achillea fragrantissima.
BMC complementary and alternative medicine.
2011 Oct; 11(?):98. doi:
10.1186/1472-6882-11-98. [PMID: 22018032] - Jieun Choi, Hyun Jin Min, Jeon-Soo Shin. Increased levels of HMGB1 and pro-inflammatory cytokines in children with febrile seizures.
Journal of neuroinflammation.
2011 Oct; 8(?):135. doi:
10.1186/1742-2094-8-135. [PMID: 21989210] - Daria Mamaeva, Chantal Ripoll, Claire Bony, Marisa Teigell, Florence E Perrin, Bernard Rothhut, Ivan Bieche, Rosette Lidereau, Alain Privat, Valérie Rigau, Hélène Guillon, Florence Vachiery-Lahaye, Daniele Noel, Luc Bauchet, Jean-Philippe Hugnot. Isolation of mineralizing Nestin+ Nkx6.1+ vascular muscular cells from the adult human spinal cord.
BMC neuroscience.
2011 Oct; 12(?):99. doi:
10.1186/1471-2202-12-99. [PMID: 21985235] - Bianca Weinstock-Guttman, Robert Zivadinov, Naeem Mahfooz, Ellen Carl, Allison Drake, Jaclyn Schneider, Barbara Teter, Sara Hussein, Bijal Mehta, Marc Weiskopf, Jacqueline Durfee, Niels Bergsland, Murali Ramanathan. Serum lipid profiles are associated with disability and MRI outcomes in multiple sclerosis.
Journal of neuroinflammation.
2011 Oct; 8(?):127. doi:
10.1186/1742-2094-8-127. [PMID: 21970791] - Helle-Brit Fiebrich, Johan R de Jong, Ido P Kema, Klaas Pieter Koopmans, Wim Sluiter, Rudi A J O Dierckx, Annemiek M Walenkamp, Thera P Links, Adrienne H Brouwers, Elisabeth G E de Vries. Total 18F-dopa PET tumour uptake reflects metabolic endocrine tumour activity in patients with a carcinoid tumour.
European journal of nuclear medicine and molecular imaging.
2011 Oct; 38(10):1854-61. doi:
10.1007/s00259-011-1862-5. [PMID: 21698413] - Yukikatsu Iwasaki, Hirotada Otsuka, Nobuaki Yanagisawa, Hisashi Hisamitsu, Atsufumi Manabe, Naoko Nonaka, Masanori Nakamura. In situ proliferation and differentiation of macrophages in dental pulp.
Cell and tissue research.
2011 Oct; 346(1):99-109. doi:
10.1007/s00441-011-1231-5. [PMID: 21922246] - Nicola Logallo, Halvor Naess, Titto T Idicula, Jan Brogger, Ulrike Waje-Andreassen, Lars Thomassen. Serum uri acid: neuroprotection in thrombolysis. The Bergen NORSTROKE study.
BMC neurology.
2011 Sep; 11(?):114. doi:
10.1186/1471-2377-11-114. [PMID: 21943291] - O Hyldegaard, D Kerem, Y Melamed. Effect of isobaric breathing gas shifts from air to heliox mixtures on resolution of air bubbles in lipid and aqueous tissues of recompressed rats.
European journal of applied physiology.
2011 Sep; 111(9):2183-93. doi:
10.1007/s00421-011-1854-y. [PMID: 21318313] - Fuyuko Takata, Shinya Dohgu, Junichi Matsumoto, Hiroyuki Takahashi, Takashi Machida, Tomoya Wakigawa, Eriko Harada, Haruki Miyaji, Mitsuhisa Koga, Tsuyoshi Nishioku, Atsushi Yamauchi, Yasufumi Kataoka. Brain pericytes among cells constituting the blood-brain barrier are highly sensitive to tumor necrosis factor-α, releasing matrix metalloproteinase-9 and migrating in vitro.
Journal of neuroinflammation.
2011 Aug; 8(?):106. doi:
10.1186/1742-2094-8-106. [PMID: 21867555] - Victor Friedrich, Rowena Flores, Artur Muller, Weina Bi, Ellinor Ib Peerschke, Fatima A Sehba. Reduction of neutrophil activity decreases early microvascular injury after subarachnoid haemorrhage.
Journal of neuroinflammation.
2011 Aug; 8(?):103. doi:
10.1186/1742-2094-8-103. [PMID: 21854561] - Caroline Drake, Hervé Boutin, Matthew S Jones, Adam Denes, Barry W McColl, Johann R Selvarajah, Sharon Hulme, Rachel F Georgiou, Rainer Hinz, Alexander Gerhard, Andy Vail, Christian Prenant, Peter Julyan, Renaud Maroy, Gavin Brown, Alison Smigova, Karl Herholz, Michael Kassiou, David Crossman, Sheila Francis, Spencer D Proctor, James C Russell, Stephen J Hopkins, Pippa J Tyrrell, Nancy J Rothwell, Stuart M Allan. Brain inflammation is induced by co-morbidities and risk factors for stroke.
Brain, behavior, and immunity.
2011 Aug; 25(6):1113-22. doi:
10.1016/j.bbi.2011.02.008. [PMID: 21356305] - Y-M Cho, H-F Pu, W J Huang, L-T Ho, S-W Wang, P S Wang. Role of serum- and glucocorticoid-inducible kinase-1 in regulating torsion-induced apoptosis in rats.
International journal of andrology.
2011 Aug; 34(4):379-89. doi:
10.1111/j.1365-2605.2010.01091.x. [PMID: 20738430] - E A Rabiner, J Beaver, A Makwana, G Searle, C Long, P J Nathan, R D Newbould, J Howard, S R Miller, M A Bush, S Hill, R Reiley, J Passchier, R N Gunn, P M Matthews, E T Bullmore. Pharmacological differentiation of opioid receptor antagonists by molecular and functional imaging of target occupancy and food reward-related brain activation in humans.
Molecular psychiatry.
2011 Aug; 16(8):826-35, 785. doi:
10.1038/mp.2011.29. [PMID: 21502953] - Haytham Eloqayli, Torun M Melø, Anne Haukvik, Ursula Sonnewald. [2,4-(13)C]β-hydroxybutyrate metabolism in astrocytes and C6 glioblastoma cells.
Neurochemical research.
2011 Aug; 36(8):1566-73. doi:
10.1007/s11064-011-0485-3. [PMID: 21538079] - Weena J Y Chen, Luuk J Rijzewijk, Rutger W van der Meer, Martijn W Heymans, Eelco van Duinkerken, Mark Lubberink, Adriaan A Lammertsma, Hildo J Lamb, Albert de Roos, Johannes A Romijn, Jan W A Smit, Jeroen J Bax, Mette Bjerre, Jan Frystyk, Allan Flyvbjerg, Michaela Diamant. Association of plasma osteoprotegerin and adiponectin with arterial function, cardiac function and metabolism in asymptomatic type 2 diabetic men.
Cardiovascular diabetology.
2011 Jul; 10(?):67. doi:
10.1186/1475-2840-10-67. [PMID: 21771299] - Mushfiquddin Khan, Harutoshi Sakakima, Tajinder S Dhammu, Anandakumar Shunmugavel, Yeong-Bin Im, Anne G Gilg, Avtar K Singh, Inderjit Singh. S-nitrosoglutathione reduces oxidative injury and promotes mechanisms of neurorepair following traumatic brain injury in rats.
Journal of neuroinflammation.
2011 Jul; 8(?):78. doi:
10.1186/1742-2094-8-78. [PMID: 21733162] - Jan Florian Heuer, Paolo Pelosi, Peter Hermann, Christina Perske, Thomas A Crozier, Wolfgang Brück, Michael Quintel. Acute effects of intracranial hypertension and ARDS on pulmonary and neuronal damage: a randomized experimental study in pigs.
Intensive care medicine.
2011 Jul; 37(7):1182-91. doi:
10.1007/s00134-011-2232-2. [PMID: 21544692] - Muhammad Zafrullah Arifin, Ahmad Faried, Muhammad Nurhalim Shahib, Kahdar Wiriadisastra, Tatang Bisri. Inhibition of activated NR2B gene- and caspase-3 protein-expression by glutathione following traumatic brain injury in a rat model.
Asian journal of neurosurgery.
2011 Jul; 6(2):72-7. doi:
10.4103/1793-5482.92160. [PMID: 22347327] - Ana R Inácio, Richard Bucala, Tomas Deierborg. Lack of macrophage migration inhibitory factor in mice does not affect hallmarks of the inflammatory/immune response during the first week after stroke.
Journal of neuroinflammation.
2011 Jun; 8(?):75. doi:
10.1186/1742-2094-8-75. [PMID: 21714902] - Stefania Mondello, Linda Papa, Andras Buki, M Ross Bullock, Endre Czeiter, Frank C Tortella, Kevin K Wang, Ronald L Hayes. Neuronal and glial markers are differently associated with computed tomography findings and outcome in patients with severe traumatic brain injury: a case control study.
Critical care (London, England).
2011 Jun; 15(3):R156. doi:
10.1186/cc10286. [PMID: 21702960] - Juliann G Kiang, Neil G Agravante, Joan T Smith, Phillip D Bowman. 17-DMAG diminishes hemorrhage-induced small intestine injury by elevating Bcl-2 protein and inhibiting iNOS pathway, TNF-α increase, and caspase-3 activation.
Cell & bioscience.
2011 Jun; 1(1):21. doi:
10.1186/2045-3701-1-21. [PMID: 21711488] - Pratibha V Nerurkar, Lisa M Johns, Lance M Buesa, Gideon Kipyakwai, Esther Volper, Ryuei Sato, Pranjal Shah, Domonkos Feher, Philip G Williams, Vivek R Nerurkar. Momordica charantia (bitter melon) attenuates high-fat diet-associated oxidative stress and neuroinflammation.
Journal of neuroinflammation.
2011 Jun; 8(?):64. doi:
10.1186/1742-2094-8-64. [PMID: 21639917] - Deepti Navaratna, Shu-Zhen Guo, Kazhuhide Hayakawa, Xiaoying Wang, Chiara Gerhardinger, Eng H Lo. Decreased cerebrovascular brain-derived neurotrophic factor-mediated neuroprotection in the diabetic brain.
Diabetes.
2011 Jun; 60(6):1789-96. doi:
10.2337/db10-1371. [PMID: 21562076] - Jennifer V Welser-Alves, Stephen J Crocker, Richard Milner. A dual role for microglia in promoting tissue inhibitor of metalloproteinase (TIMP) expression in glial cells in response to neuroinflammatory stimuli.
Journal of neuroinflammation.
2011 Jun; 8(?):61. doi:
10.1186/1742-2094-8-61. [PMID: 21631912] - Seyed Ali Mousavi, Mohammad Saadatnia, Faribourz Khorvash, Tahereh Hoseini, Payam Sariaslani. Evaluation of the neuroprotective effect of dextromethorphan in the acute phase of ischaemic stroke.
Archives of medical science : AMS.
2011 Jun; 7(3):465-9. doi:
10.5114/aoms.2011.23413. [PMID: 22295030] - Elisa Torres, Maria D Gutierrez-Lopez, Andrea Mayado, Ana Rubio, Esther O'Shea, Maria I Colado. Changes in interleukin-1 signal modulators induced by 3,4-methylenedioxymethamphetamine (MDMA): regulation by CB2 receptors and implications for neurotoxicity.
Journal of neuroinflammation.
2011 May; 8(?):53. doi:
10.1186/1742-2094-8-53. [PMID: 21595923] - Carol L Murray, Donal T Skelly, Colm Cunningham. Exacerbation of CNS inflammation and neurodegeneration by systemic LPS treatment is independent of circulating IL-1β and IL-6.
Journal of neuroinflammation.
2011 May; 8(?):50. doi:
10.1186/1742-2094-8-50. [PMID: 21586125] - Pawan K Gupta, Sudesh Prabhakar, Suresh Sharma, Akshay Anand. Vascular endothelial growth factor-A (VEGF-A) and chemokine ligand-2 (CCL2) in amyotrophic lateral sclerosis (ALS) patients.
Journal of neuroinflammation.
2011 May; 8(?):47. doi:
10.1186/1742-2094-8-47. [PMID: 21569455] - Delphine Marsac, Stephanie García, Alexandra Fournet, Adam Aguirre, Karla Pino, Marcela Ferres, Alexis M Kalergis, Marcelo Lopez-Lastra, Francisco Veas. Infection of human monocyte-derived dendritic cells by ANDES Hantavirus enhances pro-inflammatory state, the secretion of active MMP-9 and indirectly enhances endothelial permeability.
Virology journal.
2011 May; 8(?):223. doi:
10.1186/1743-422x-8-223. [PMID: 21569520] - Raquel Rodríguez-González, Tomás Sobrino, Manuel Rodríguez-Yáñez, Mónica Millán, David Brea, Elena Miranda, Octavio Moldes, Juan Pérez, David A Lomas, Rogelio Leira, Antoni Dávalos, José Castillo. Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke.
Journal of translational medicine.
2011 May; 9(?):58. doi:
10.1186/1479-5876-9-58. [PMID: 21569344] - Olof Eriksson, Bengt Långström, Ray Josephsson. Assessment of receptor occupancy-over-time of two dopamine transporter inhibitors by [(11)C]CIT and target controlled infusion.
Upsala journal of medical sciences.
2011 May; 116(2):100-6. doi:
10.3109/03009734.2011.563878. [PMID: 21443419] - Kim C C van de Ven, Bastiaan E de Galan, Marinette van der Graaf, Alexander A Shestov, Pierre-Gilles Henry, Cees J J Tack, Arend Heerschap. Effect of acute hypoglycemia on human cerebral glucose metabolism measured by ¹³C magnetic resonance spectroscopy.
Diabetes.
2011 May; 60(5):1467-73. doi:
10.2337/db10-1592. [PMID: 21464446] - Liang Zhang, Manoj Bhasin, Rachel Schor-Bardach, Xiaoen Wang, Michael P Collins, David Panka, Prabhakar Putheti, Sabina Signoretti, David C Alsop, Towia Libermann, Michael B Atkins, James W Mier, S Nahum Goldberg, Rupal S Bhatt. Resistance of renal cell carcinoma to sorafenib is mediated by potentially reversible gene expression.
PloS one.
2011 Apr; 6(4):e19144. doi:
10.1371/journal.pone.0019144. [PMID: 21559452] - Yelena Y Grinberg, John G Milton, Richard P Kraig. Spreading depression sends microglia on Lévy flights.
PloS one.
2011 Apr; 6(4):e19294. doi:
10.1371/journal.pone.0019294. [PMID: 21541289] - Maite Verreault, Dita Strutt, Dana Masin, Malathi Anantha, Andrew Yung, Piotr Kozlowski, Dawn Waterhouse, Marcel B Bally, Donald T Yapp. Vascular normalization in orthotopic glioblastoma following intravenous treatment with lipid-based nanoparticulate formulations of irinotecan (Irinophore C™), doxorubicin (Caelyx®) or vincristine.
BMC cancer.
2011 Apr; 11(?):124. doi:
10.1186/1471-2407-11-124. [PMID: 21477311] - Heidi Ormstad, Hans Christian Dalsbotten Aass, Niels Lund-Sørensen, Karl-Friedrich Amthor, Leif Sandvik. Serum levels of cytokines and C-reactive protein in acute ischemic stroke patients, and their relationship to stroke lateralization, type, and infarct volume.
Journal of neurology.
2011 Apr; 258(4):677-85. doi:
10.1007/s00415-011-6006-0. [PMID: 21424610] - Heidi Ormstad, Hans Christian Dalsbotten Aass, Karl-Friedrich Amthor, Niels Lund-Sørensen, Leiv Sandvik. Serum cytokine and glucose levels as predictors of poststroke fatigue in acute ischemic stroke patients.
Journal of neurology.
2011 Apr; 258(4):670-6. doi:
10.1007/s00415-011-5962-8. [PMID: 21365457] - Xin Lv, Liqun Yang, Kunming Tao, Yantao Liu, Tian Yang, Guozhong Chen, Weifeng Yu, Hao Lv, Feixiang Wu. Isoflurane preconditioning at clinically relevant doses induce protective effects of heme oxygenase-1 on hepatic ischemia reperfusion in rats.
BMC gastroenterology.
2011 Mar; 11(?):31. doi:
10.1186/1471-230x-11-31. [PMID: 21453462] - Cho Hee Kim, Hyun Min Jeon, Su Yeon Lee, Min Kyung Ju, Ji Young Moon, Hye Gyeong Park, Mi-Ae Yoo, Byung Tae Choi, Jong In Yook, Sung-Chul Lim, Song Iy Han, Ho Sung Kang. Implication of snail in metabolic stress-induced necrosis.
PloS one.
2011 Mar; 6(3):e18000. doi:
10.1371/journal.pone.0018000. [PMID: 21448462] - Wei Li, Shu Zhu, Jianhua Li, Yan Huang, Rongrong Zhou, Xuegong Fan, Huan Yang, Xing Gong, N Tony Eissa, Willi Jahnen-Dechent, Ping Wang, Kevin J Tracey, Andrew E Sama, Haichao Wang. A hepatic protein, fetuin-A, occupies a protective role in lethal systemic inflammation.
PloS one.
2011 Feb; 6(2):e16945. doi:
10.1371/journal.pone.0016945. [PMID: 21347455] - Ryszard M Pluta, Edward H Oldfield, Kamran D Bakhtian, Ali Reza Fathi, René K Smith, Hetty L Devroom, Masoud Nahavandi, Sukyung Woo, William D Figg, Russell R Lonser. Safety and feasibility of long-term intravenous sodium nitrite infusion in healthy volunteers.
PloS one.
2011 Jan; 6(1):e14504. doi:
10.1371/journal.pone.0014504. [PMID: 21249218] - Shihui Sun, Yan Guo, Guangyu Zhao, Xiaojun Zhou, Junfeng Li, Jingya Hu, Hong Yu, Yu Chen, Hongbin Song, Fei Qiao, Guilian Xu, Fei Yang, Yuzhang Wu, Stephen Tomlinson, Zhongping Duan, Yusen Zhou. Complement and the alternative pathway play an important role in LPS/D-GalN-induced fulminant hepatic failure.
PloS one.
2011; 6(11):e26838. doi:
10.1371/journal.pone.0026838. [PMID: 22069473] - Phil Hyu Lee, Han-Soo Kim, Ji E Lee, Youjeong Choi, Jin Yong Hong, Hyo Suk Nam, Young H Sohn, Hyun Ok Kim. Comparison of endothelial progenitor cells in Parkinson's disease patients treated with levodopa and levodopa/COMT inhibitor.
PloS one.
2011; 6(6):e21536. doi:
10.1371/journal.pone.0021536. [PMID: 21738693] - Jarel Gandhi, Siobhan M Cashman, Rajendra Kumar-Singh. Soluble CD59 expressed from an adenovirus in vivo is a potent inhibitor of complement deposition on murine liver vascular endothelium.
PloS one.
2011; 6(6):e21621. doi:
10.1371/journal.pone.0021621. [PMID: 21720565] - Arthur Liesz, Li Sun, Wei Zhou, Sönke Schwarting, Eva Mracsko, Markus Zorn, Henrike Bauer, Clemens Sommer, Roland Veltkamp. FTY720 reduces post-ischemic brain lymphocyte influx but does not improve outcome in permanent murine cerebral ischemia.
PloS one.
2011; 6(6):e21312. doi:
10.1371/journal.pone.0021312. [PMID: 21701599] - Thomas J Degraba, Gerard T Hoehn, Paul A Nyquist, Honghui Wang, Ray Kenney, Denise A Gonzales, Steven J Kern, Sai-Xia Ying, Peter J Munson, Anthony F Suffredini. Biomarker discovery in serum from patients with carotid atherosclerosis.
Cerebrovascular diseases extra.
2011 Jan; 1(1):115-29. doi:
10.1159/000334477. [PMID: 22566989] - Deepti Nair, Ehab A Dayyat, Shelley X Zhang, Yang Wang, David Gozal. Intermittent hypoxia-induced cognitive deficits are mediated by NADPH oxidase activity in a murine model of sleep apnea.
PloS one.
2011; 6(5):e19847. doi:
10.1371/journal.pone.0019847. [PMID: 21625437] - Noemi Morello, Federico Tommaso Bianchi, Paola Marmiroli, Elisabetta Tonoli, Virginia Rodriguez Menendez, Lorenzo Silengo, Guido Cavaletti, Alessandro Vercelli, Fiorella Altruda, Emanuela Tolosano. A role for hemopexin in oligodendrocyte differentiation and myelin formation.
PloS one.
2011; 6(5):e20173. doi:
10.1371/journal.pone.0020173. [PMID: 21633699]