Cbz-DL-Val-DL-Ala-DL-Asp-AcF (BioDeep_00000912437)
代谢物信息卡片
Cbz-DL-Val-DL-Ala-DL-Asp-AcF
化学式: C22H28FN3O8 (481.186034)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)C(C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)C(=O)CF)NC(=O)OCC1=CC=CC=C1
InChI: InChI=1S/C22H28FN3O8/c1-12(2)18(26-22(33)34-11-14-7-5-4-6-8-14)21(32)24-13(3)20(31)25-15(9-17(28)29)19(30)16(27)10-23/h4-8,12-13,15,18H,9-11H2,1-3H3,(H,24,32)(H,25,31)(H,26,33)(H,28,29)
描述信息
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D015853 - Cysteine Proteinase Inhibitors
D009676 - Noxae > D000477 - Alkylating Agents > D000590 - Amino Acid Chloromethyl Ketones
D002491 - Central Nervous System Agents > D018696 - Neuroprotective Agents
D020011 - Protective Agents
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
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PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Rittibet Yapasert, Patompong Khaw-On, Ratana Banjerdpongchai. Coronavirus Infection-Associated Cell Death Signaling and Potential Therapeutic Targets.
Molecules (Basel, Switzerland).
2021 Dec; 26(24):. doi:
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Molecular and cellular endocrinology.
2021 03; 523(?):111135. doi:
10.1016/j.mce.2020.111135. [PMID: 33359761] - Alejandro A Puchol Tarazona, Daniel Maresch, Annette Grill, Janet Bakalarz, Juan A Torres Acosta, Alexandra Castilho, Herta Steinkellner, Lukas Mach. Identification of two subtilisin-like serine proteases engaged in the degradation of recombinant proteins in Nicotiana benthamiana.
FEBS letters.
2021 02; 595(3):379-388. doi:
10.1002/1873-3468.14014. [PMID: 33263189] - Chun-Yu Liu, Min Wang, Hong-Min Yu, Fang-Xuan Han, Qiong-Shi Wu, Xing-Jun Cai, Hiroshi Kurihara, Yong-Xing Chen, Yi-Fang Li, Rong-Rong He. Ferroptosis is involved in alcohol-induced cell death in vivo and in vitro.
Bioscience, biotechnology, and biochemistry.
2020 Aug; 84(8):1621-1628. doi:
10.1080/09168451.2020.1763155. [PMID: 32419644] - Josef Stolberg-Stolberg, Meike Sambale, Uwe Hansen, Alexandra Schäfer Michael Raschke, Jessica Bertrand, Thomas Pap, Joanna Sherwood. Cartilage Trauma Induces Necroptotic Chondrocyte Death and Expulsion of Cellular Contents.
International journal of molecular sciences.
2020 Jun; 21(12):. doi:
10.3390/ijms21124204. [PMID: 32545631] - Junyu Dong, Zhihong Jiang, Guorui Ma. Hsp90 inhibition aggravates adriamycin-induced podocyte injury through intrinsic apoptosis pathway.
Experimental cell research.
2020 05; 390(2):111928. doi:
10.1016/j.yexcr.2020.111928. [PMID: 32156599] - Katsuya Iuchi, Sayo Shirai, Yuji Tasaki, Hisashi Hisatomi. Heterocyclic organobismuth(III) compound induces nonapoptotic cell death via lipid peroxidation.
Anti-cancer drugs.
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10.1097/cad.0000000000000841. [PMID: 31609767] - Jiancheng Chen, Shunsuke Kuroki, Masataka Someda, Shin Yonehara. Interferon-γ induces the cell surface exposure of phosphatidylserine by activating the protein MLKL in the absence of caspase-8 activity.
The Journal of biological chemistry.
2019 08; 294(32):11994-12006. doi:
10.1074/jbc.ra118.007161. [PMID: 31217278] - Ziqiao Yuan, Haoran Zhang, Muhammad Hasnat, Jiaxin Ding, Xi Chen, Peishi Liang, Lixin Sun, Luyong Zhang, Zhenzhou Jiang. A new perspective of triptolide-associated hepatotoxicity: Liver hypersensitivity upon LPS stimulation.
Toxicology.
2019 02; 414(?):45-56. doi:
10.1016/j.tox.2019.01.005. [PMID: 30633930] - Gyu-Tae Shin, Hwa Joung Lee, Ji Eun Park. Growth arrest and DNA damage 45γ is required for caspase-dependent renal tubular cell apoptosis.
PloS one.
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
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Life sciences.
2018 Apr; 198(?):8-17. doi:
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International journal of oncology.
2018 Mar; 52(3):1011-1022. doi:
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Molecular and cellular biochemistry.
2017 Nov; 435(1-2):15-24. doi:
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Journal of cellular and molecular medicine.
2017 Nov; 21(11):2720-2731. doi:
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Molecules (Basel, Switzerland).
2017 Sep; 22(9):. doi:
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Molecules (Basel, Switzerland).
2017 Aug; 22(8):. doi:
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Environmental toxicology.
2017 Jul; 32(7):1857-1868. doi:
10.1002/tox.22408. [PMID: 28251795] - Ying Huang, Osamu Ohno, Kiyotake Suenaga, Kenji Miyamoto. Apoptosis-inducing activity and antiproliferative effect of Paeoniflorigenone from moutan cortex.
Bioscience, biotechnology, and biochemistry.
2017 Jun; 81(6):1106-1113. doi:
10.1080/09168451.2017.1300517. [PMID: 28317437] - Albert J van Hell, Adriana Haimovitz-Friedman, Zvi Fuks, William D Tap, Richard Kolesnick. Gemcitabine kills proliferating endothelial cells exclusively via acid sphingomyelinase activation.
Cellular signalling.
2017 06; 34(?):86-91. doi:
10.1016/j.cellsig.2017.02.021. [PMID: 28238856] - Megan M Bernard, Jason R McConnery, David W Hoskin. [10]-Gingerol, a major phenolic constituent of ginger root, induces cell cycle arrest and apoptosis in triple-negative breast cancer cells.
Experimental and molecular pathology.
2017 04; 102(2):370-376. doi:
10.1016/j.yexmp.2017.03.006. [PMID: 28315687] - Benjamin L Woolbright, C David Williams, Hongmin Ni, Sean C Kumer, Timothy Schmitt, Bartholomew Kane, Hartmut Jaeschke. Microcystin-LR induced liver injury in mice and in primary human hepatocytes is caused by oncotic necrosis.
Toxicon : official journal of the International Society on Toxinology.
2017 Jan; 125(?):99-109. doi:
10.1016/j.toxicon.2016.11.254. [PMID: 27889601] - Jasmin Dächert, Hannah Schoeneberger, Katharina Rohde, Simone Fulda. RSL3 and Erastin differentially regulate redox signaling to promote Smac mimetic-induced cell death.
Oncotarget.
2016 Sep; 7(39):63779-63792. doi:
10.18632/oncotarget.11687. [PMID: 27588473] - Takashi Kasukabe, Yoshio Honma, Junko Okabe-Kado, Yusuke Higuchi, Nobuo Kato, Shunichi Kumakura. Combined treatment with cotylenin A and phenethyl isothiocyanate induces strong antitumor activity mainly through the induction of ferroptotic cell death in human pancreatic cancer cells.
Oncology reports.
2016 Aug; 36(2):968-76. doi:
10.3892/or.2016.4867. [PMID: 27375275] - Letizia Polito, Massimo Bortolotti, Manuela Pedrazzi, Daniele Mercatelli, Maria Giulia Battelli, Andrea Bolognesi. Apoptosis and necroptosis induced by stenodactylin in neuroblastoma cells can be completely prevented through caspase inhibition plus catalase or necrostatin-1.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2016 Jan; 23(1):32-41. doi:
10.1016/j.phymed.2015.11.006. [PMID: 26902405] - Cara Ellis, James G Lyon, Gregory S Korbutt. Optimization and Scale-up Isolation and Culture of Neonatal Porcine Islets: Potential for Clinical Application.
Cell transplantation.
2016; 25(3):539-47. doi:
10.3727/096368915x689451. [PMID: 26377964] - Pei Yin, Jinpeng Jia, Jijun Li, Yan Song, Yiyan Zhang, Fengkun Chen. ABT-737, a Bcl-2 Selective Inhibitor, and Chloroquine Synergistically Kill Renal Cancer Cells.
Oncology research.
2016; 24(1):65-72. doi:
10.3727/096504016x14587366983838. [PMID: 27178823] - Saroj Kumar Amar, Shruti Goyal, Divya Dubey, Ajeet K Srivastav, Deepti Chopra, Jyoti Singh, Jai Shankar, Rajnish K Chaturvedi, Ratan Singh Ray. Benzophenone 1 induced photogenotoxicity and apoptosis via release of cytochrome c and Smac/DIABLO at environmental UV radiation.
Toxicology letters.
2015 Dec; 239(3):182-93. doi:
10.1016/j.toxlet.2015.09.024. [PMID: 26440554] - Ya-Fang Huang, Pei-Chi Lo, Chia-Liang Yen, Peter Andrija Nigrovic, Wen-Chen Chao, Wei-Zhi Wang, George Chengkang Hsu, Yau-Sheng Tsai, Chi-Chang Shieh. Redox Regulation of Pro-IL-1β Processing May Contribute to the Increased Severity of Serum-Induced Arthritis in NOX2-Deficient Mice.
Antioxidants & redox signaling.
2015 Oct; 23(12):973-84. doi:
10.1089/ars.2014.6136. [PMID: 25867281] - Maïté Fransolet, Laurie Henry, Soraya Labied, Agnès Noël, Michelle Nisolle, Carine Munaut. In vitro evaluation of the anti-apoptotic drug Z-VAD-FMK on human ovarian granulosa cell lines for further use in ovarian tissue transplantation.
Journal of assisted reproduction and genetics.
2015 Oct; 32(10):1551-9. doi:
10.1007/s10815-015-0536-9. [PMID: 26169075] - Hirofumi Sawai, Hideo Ogiso, Toshiro Okazaki. Differential changes in sphingolipids between TNF-induced necroptosis and apoptosis in U937 cells and necroptosis-resistant sublines.
Leukemia research.
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10.1016/j.leukres.2015.06.002. [PMID: 26189109] - Sang Eun Kim, Hye-Jin Park, Hye Kyoung Jeong, Mi-Jung Kim, Minyeong Kim, Ok-Nam Bae, Seung-Hoon Baek. Autophagy sustains the survival of human pancreatic cancer PANC-1 cells under extreme nutrient deprivation conditions.
Biochemical and biophysical research communications.
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10.1016/j.bbrc.2015.05.022. [PMID: 25998396] - Allan Sauvat, Yidan Wang, Florian Segura, Sabrina Spaggiari, Kevin Müller, Heng Zhou, Lorenzo Galluzzi, Oliver Kepp, Guido Kroemer. Quantification of cellular viability by automated microscopy and flow cytometry.
Oncotarget.
2015 Apr; 6(11):9467-75. doi:
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PloS one.
2015; 10(5):e0125774. doi:
10.1371/journal.pone.0125774. [PMID: 25946033] - Ai-Li Cao, Qing-Feng Tang, Wen-Chao Zhou, Yan-Yan Qiu, Song-Jiao Hu, Pei-Hao Yin. Ras/ERK signaling pathway is involved in curcumin-induced cell cycle arrest and apoptosis in human gastric carcinoma AGS cells.
Journal of Asian natural products research.
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Cell biochemistry and function.
2014 Dec; 32(8):647-56. doi:
10.1002/cbf.3068. [PMID: 25289565] - Yan-yan Tao, Xiu-chuan Yan, Tao Zhou, Li Shen, Zu-long Liu, Cheng-hai Liu. Fuzheng Huayu recipe alleviates hepatic fibrosis via inhibiting TNF-α induced hepatocyte apoptosis.
BMC complementary and alternative medicine.
2014 Nov; 14(?):449. doi:
10.1186/1472-6882-14-449. [PMID: 25407538] - Bing Hu, Qin Du, Shan Deng, Hong-Mei An, Chuan-Fang Pan, Ke-Ping Shen, Ling Xu, Meng-Meng Wei, Shuang-Shuang Wang. Ligustrum lucidum Ait. fruit extract induces apoptosis and cell senescence in human hepatocellular carcinoma cells through upregulation of p21.
Oncology reports.
2014 Sep; 32(3):1037-42. doi:
10.3892/or.2014.3312. [PMID: 25017491] - Su Jin Lee, Jae Do Yoo, Soo Young Choi, Oh-Shin Kwon. The expression and secretion of vimentin in the progression of non-alcoholic steatohepatitis.
BMB reports.
2014 Aug; 47(8):457-62. doi:
10.5483/bmbrep.2014.47.8.256. [PMID: 24325816] - Xinling Liang, Yuanhan Chen, Li Zhang, Fen Jiang, Wenjian Wang, Zhiming Ye, Shuangxin Liu, Chunping Yu, Wei Shi. Necroptosis, a novel form of caspase-independent cell death, contributes to renal epithelial cell damage in an ATP-depleted renal ischemia model.
Molecular medicine reports.
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10.3892/mmr.2014.2234. [PMID: 24842629] - Chao Feng, Sheng-Xiong Huang, Xue-Mei Gao, Hong-Xi Xu, Kathy Qian Luo. Characterization of proapoptotic compounds from the bark of Garcinia oblongifolia.
Journal of natural products.
2014 May; 77(5):1111-6. doi:
10.1021/np4007316. [PMID: 24754786] - Barbara Klein, Ursula Lütz-Meindl, Hubert H Kerschbaum. From the nucleus to the plasma membrane: translocation of the nuclear proteins histone H3 and lamin B1 in apoptotic microglia.
Apoptosis : an international journal on programmed cell death.
2014 May; 19(5):759-75. doi:
10.1007/s10495-014-0970-7. [PMID: 24558118] - Eri Fukunaga, Yumi Hirao, Ikuko Ogata-Ikeda, Yumiko Nishimura, Hakaru Seo, Yasuo Oyama. Bisabololoxide A, one of the constituents in German chamomile extract, attenuates cell death induced by calcium overload.
Phytotherapy research : PTR.
2014 May; 28(5):685-91. doi:
10.1002/ptr.5041. [PMID: 23873581] - Maria Dolores Sanchez-Niño, Jonay Poveda, Ana Belen Sanz, Susana Carrasco, Marta Ruiz-Ortega, Rafael Selgas, Jesus Egido, Alberto Ortiz. 3,4-DGE is cytotoxic and decreases HSP27/HSPB1 in podocytes.
Archives of toxicology.
2014 Mar; 88(3):597-608. doi:
10.1007/s00204-013-1181-7. [PMID: 24337777] - Guang Zhang, Chunping Jiang, Zhongxia Wang, Weibo Chen, Wen Gu, Yitao Ding. Dehydroabietic acid derivative QC2 induces oncosis in hepatocellular carcinoma cells.
BioMed research international.
2014; 2014(?):682197. doi:
10.1155/2014/682197. [PMID: 25110686] - Xiao-Fei Wang, Yi-Bing Zhao, Qiang Wu, Zhi-Hua Sun, Hai-Jin Li. Triptolide induces apoptosis in endometrial cancer via a p53‑independent mitochondrial pathway.
Molecular medicine reports.
2014 Jan; 9(1):39-44. doi:
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Free radical biology & medicine.
2013 Dec; 65(?):1352-1362. doi:
10.1016/j.freeradbiomed.2013.10.007. [PMID: 24120969] - Cheng-Yun Jin, Hai Yang Yu, Cheol Park, Min Ho Han, Su Hyun Hong, Kyoung-Sook Kim, Young-Choon Lee, Young-Chae Chang, Jaehun Cheong, Sung-Kwon Moon, Gi-Young Kim, Hyung-In Moon, Wun-Jae Kim, Jai-Heon Lee, Yung Hyun Choi. Oleifolioside B-mediated autophagy promotes apoptosis in A549 human non-small cell lung cancer cells.
International journal of oncology.
2013 Dec; 43(6):1943-50. doi:
10.3892/ijo.2013.2143. [PMID: 24141596] - Ying Liu, Jian-Hong Liu, Kuan Chai, Shin-Ichi Tashiro, Satoshi Onodera, Takashi Ikejima. Inhibition of c-Met promoted apoptosis, autophagy and loss of the mitochondrial transmembrane potential in oridonin-induced A549 lung cancer cells.
The Journal of pharmacy and pharmacology.
2013 Nov; 65(11):1622-42. doi:
10.1111/jphp.12140. [PMID: 24102522] - Chia-Che Chang, Jui-Sheng Lai, Chi-Shiuan Tsai, Song-Wei Ma, Jyun-Yi Lin, Lan-Ru Huang, Chien-Hsing Lu, En-Chih Liao, Tsing-Fen Ho. Proapoptotic and TRAIL-sensitizing constituents isolated from Salvia militiorrhiza (Danshen).
Journal of bioscience and bioengineering.
2013 Oct; 116(4):516-23. doi:
10.1016/j.jbiosc.2013.04.015. [PMID: 23660075] - Phullara B Shelat, Leigh D Plant, Janice C Wang, Elizabeth Lee, Jeremy D Marks. The membrane-active tri-block copolymer pluronic F-68 profoundly rescues rat hippocampal neurons from oxygen-glucose deprivation-induced death through early inhibition of apoptosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2013 Jul; 33(30):12287-99. doi:
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Kidney international.
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Acta medica Okayama.
2013; 67(3):153-64. doi:
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Oncology reports.
2012 Dec; 28(6):2227-32. doi:
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Oncology reports.
2012 Nov; 28(5):1910-6. doi:
10.3892/or.2012.1962. [PMID: 22895655] - Hye Jeong Kim, Min Ho Han, Gi Young Kim, Young-Whan Choi, Yung Hyun Choi. Hexane extracts of garlic cloves induce apoptosis through the generation of reactive oxygen species in Hep3B human hepatocarcinoma cells.
Oncology reports.
2012 Nov; 28(5):1757-63. doi:
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American journal of physiology. Renal physiology.
2012 Oct; 303(8):F1239-50. doi:
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Journal of hepatology.
2012 Oct; 57(4):844-51. doi:
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European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2012 Sep; 47(2):464-73. doi:
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Proceedings of the National Academy of Sciences of the United States of America.
2012 Sep; 109(37):14983-8. doi:
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Stem cells and development.
2012 Sep; 21(13):2495-507. doi:
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BMC complementary and alternative medicine.
2012 Jul; 12(?):93. doi:
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Investigational new drugs.
2012 Jun; 30(3):1012-27. doi:
10.1007/s10637-011-9668-7. [PMID: 21494837] - L H Huang, Q J Yan, N K Kopparapu, Z Q Jiang, Y Sun. Astragalus membranaceus lectin (AML) induces caspase-dependent apoptosis in human leukemia cells.
Cell proliferation.
2012 Feb; 45(1):15-21. doi:
10.1111/j.1365-2184.2011.00800.x. [PMID: 22172162] - Deok-Seon Ryu, Hyeong-Seon Lee, Gyeong-Seon Lee, Dong-Seok Lee. Effects of the ethylacetate extract of Orostachys japonicus on induction of apoptosis through the p53-mediated signaling pathway in human gastric cancer cells.
Biological & pharmaceutical bulletin.
2012; 35(5):660-5. doi:
10.1248/bpb.35.660. [PMID: 22687398] - Taiko Yoshida, Akira Shimizu, Yukinari Masuda, Akiko Mii, Emiko Fujita, Kaoru Yoshizaki, Seiichiro Higo, Go Kanzaki, Yusuke Kajimoto, Hideki Takano, Yuh Fukuda. Caspase-3-independent internucleosomal DNA fragmentation in ischemic acute kidney injury.
Nephron. Experimental nephrology.
2012; 120(3):e103-13. doi:
10.1159/000337358. [PMID: 22678593] - Teresa Mencherini, Patrizia Picerno, Michela Festa, Paola Russo, Anna Capasso, Rita Aquino. Triterpenoid constituents from the roots of Paeonia rockii ssp. rockii.
Journal of natural products.
2011 Oct; 74(10):2116-21. doi:
10.1021/np200359v. [PMID: 21954959] - Nicola B Skerman, Annie M Joubert, Marianne J Cronjé. The apoptosis inducing effects of Sutherlandia spp. extracts on an oesophageal cancer cell line.
Journal of ethnopharmacology.
2011 Oct; 137(3):1250-60. doi:
10.1016/j.jep.2011.07.054. [PMID: 21824511] - Henriette Kauntz, Souad Bousserouel, Francine Gossé, Francis Raul. Silibinin triggers apoptotic signaling pathways and autophagic survival response in human colon adenocarcinoma cells and their derived metastatic cells.
Apoptosis : an international journal on programmed cell death.
2011 Oct; 16(10):1042-53. doi:
10.1007/s10495-011-0631-z. [PMID: 21779837] - Dong-Yan Shen, Jin-He Kang, Wei Song, Wen-Qing Zhang, Wen-Gang Li, Yan Zhao, Qing-Xi Chen. Apoptosis of human cholangiocarcinoma cell lines induced by β-escin through mitochondrial caspase-dependent pathway.
Phytotherapy research : PTR.
2011 Oct; 25(10):1519-26. doi:
10.1002/ptr.3435. [PMID: 21394804] - Jinglei Cai, Noriko Mutoh, Jeong-Oh Shin, Nobuyuki Tani-Ishii, Hayato Ohshima, Sung-Won Cho, Han-Sung Jung. Wnt5a plays a crucial role in determining tooth size during murine tooth development.
Cell and tissue research.
2011 Sep; 345(3):367-77. doi:
10.1007/s00441-011-1224-4. [PMID: 21879290] - Moo Rim Kang, Hwan Mook Kim, Jong Soon Kang, Kiho Lee, Sung Dong Lee, Dong-Hoon Hyun, Man-Jin In, Song-Kyu Park, Dong Chung Kim. Lipid-soluble ginseng extract induces apoptosis and G0/G1 cell cycle arrest in NCI-H460 human lung cancer cells.
Plant foods for human nutrition (Dordrecht, Netherlands).
2011 Jun; 66(2):101-6. doi:
10.1007/s11130-011-0232-6. [PMID: 21611769] - Min Jung Choi, Eun Jung Park, Jung Hwa Oh, Kyoung-Jin Min, Eun Sun Yang, Young Ho Kim, Tae Jin Lee, Sang Hyun Kim, Yung Hyun Choi, Jong-Wook Park, Taeg Kyu Kwon. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation.
Chemico-biological interactions.
2011 Apr; 190(2-3):102-8. doi:
10.1016/j.cbi.2011.02.013. [PMID: 21334318] - Eric J Tsang, Christopher K Arakawa, Patricia A Zuk, Benjamin M Wu. Osteoblast interactions within a biomimetic apatite microenvironment.
Annals of biomedical engineering.
2011 Apr; 39(4):1186-200. doi:
10.1007/s10439-010-0245-6. [PMID: 21234689] - Wei Ren, Stephen J Beebe. An apoptosis targeted stimulus with nanosecond pulsed electric fields (nsPEFs) in E4 squamous cell carcinoma.
Apoptosis : an international journal on programmed cell death.
2011 Apr; 16(4):382-93. doi:
10.1007/s10495-010-0572-y. [PMID: 21213047] - Faisal Thayyullathil, Shahanas Chathoth, Allen Shahin, Jaleel Kizhakkayil, Abdulkader Hago, Mahendra Patel, Sehamuddin Galadari. Protein phosphatase 1-dependent dephosphorylation of Akt is the prime signaling event in sphingosine-induced apoptosis in Jurkat cells.
Journal of cellular biochemistry.
2011 Apr; 112(4):1138-53. doi:
10.1002/jcb.23033. [PMID: 21308747] - Qi Hou, Junfei Jin, Hui Zhou, Sergei A Novgorodov, Alicja Bielawska, Zdzislaw M Szulc, Yusuf A Hannun, Lina M Obeid, Yi-Te Hsu. Mitochondrially targeted ceramides preferentially promote autophagy, retard cell growth, and induce apoptosis.
Journal of lipid research.
2011 Feb; 52(2):278-88. doi:
10.1194/jlr.m012161. [PMID: 21081756] - Jayaraj Ravindran, Nimesh Gupta, Mona Agrawal, A S Bala Bhaskar, P V Lakshmana Rao. Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism.
Apoptosis : an international journal on programmed cell death.
2011 Feb; 16(2):145-61. doi:
10.1007/s10495-010-0554-0. [PMID: 21082355] - Yi Luo, Xiaoling Li, Xiaochun Huang, Yum-Shing Wong, Tianfeng Chen, Yibo Zhang, Wenjie Zheng. 1,4-Diselenophene-1,4-diketone triggers caspase-dependent apoptosis in human melanoma A375 cells through induction of mitochondrial dysfunction.
Chemical & pharmaceutical bulletin.
2011; 59(10):1227-32. doi:
10.1248/cpb.59.1227. [PMID: 21963631] - Ji-Hyun Kim, Yeong-In Yang, Kyung-Tae Lee, Hee-Juhn Park, Jung-Hye Choi. Costunolide induces apoptosis in human endometriotic cells through inhibition of the prosurvival Akt and nuclear factor kappa B signaling pathway.
Biological & pharmaceutical bulletin.
2011; 34(4):580-5. doi:
10.1248/bpb.34.580. [PMID: 21467650] - David B Rivers, Fevzi Uçkan, Ekrem Ergin, Donald A Keefer. Pathological and ultrastructural changes in cultured cells induced by venom from the ectoparasitic wasp Nasonia vitripennis (Walker) (Hymenoptera: Pteromalidae).
Journal of insect physiology.
2010 Dec; 56(12):1935-48. doi:
10.1016/j.jinsphys.2010.08.019. [PMID: 20804763] - Li-Feng Hung, Kuo-Yen Huang, Deng-Ho Yang, Deh-Ming Chang, Jenn-Haung Lai, Ling-Jun Ho. Advanced glycation end products induce T cell apoptosis: Involvement of oxidative stress, caspase and the mitochondrial pathway.
Mechanisms of ageing and development.
2010 Nov; 131(11-12):682-91. doi:
10.1016/j.mad.2010.09.005. [PMID: 20888855] - Lian Zhang, Brian D Kavanagh, Andrew M Thorburn, D Ross Camidge. Preclinical and clinical estimates of the basal apoptotic rate of a cancer predict the amount of apoptosis induced by subsequent proapoptotic stimuli.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2010 Sep; 16(17):4478-89. doi:
10.1158/1078-0432.ccr-10-0859. [PMID: 20630997] - Chun-Yuan Cheng, Chin-Cheng Su. Tanshinone IIA inhibits Hep-J5 cells by increasing calreticulin, caspase 12 and GADD153 protein expression.
International journal of molecular medicine.
2010 Sep; 26(3):379-85. doi:
. [PMID: 20664954] - Nancy Ramia, Sawsan Ibrahim Kreydiyyeh. TNF-alpha reduces the Na+/K+ ATPase activity in LLC-PK1 cells by activating caspases and JNK and inhibiting NF-kappaB.
Cell biology international.
2010 Apr; 34(6):607-13. doi:
10.1042/cbi20090093. [PMID: 20222869] - Chien-Liang Chen, Kang-Ju Chou, Po-Tsang Lee, Ying-Shou Chen, Tsu-Yuan Chang, Chih-Yang Hsu, Wei-Chieh Huang, Hsiao-Min Chung, Hua-Chang Fang. Erythropoietin suppresses epithelial to mesenchymal transition and intercepts Smad signal transduction through a MEK-dependent mechanism in pig kidney (LLC-PK1) cell lines.
Experimental cell research.
2010 Apr; 316(7):1109-18. doi:
10.1016/j.yexcr.2010.02.022. [PMID: 20202468] - Ye Liu, Ye Guo, Hui-juan Wu, Zhi-gang Zhang, Mu-yi Guo. [Apoptosis inducing factor mediates cisplatin-induced apoptosis of renal tubular epithelial cells].
Zhonghua zhong liu za zhi [Chinese journal of oncology].
2010 Mar; 32(3):173-8. doi:
NULL. [PMID: 20450583] - Alexandre Puissant, Guillaume Robert, Nina Fenouille, Frederic Luciano, Jill-Patrice Cassuto, Sophie Raynaud, Patrick Auberger. Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation.
Cancer research.
2010 Feb; 70(3):1042-52. doi:
10.1158/0008-5472.can-09-3537. [PMID: 20103647] - Peter V Lidsky, Lyudmila I Romanova, Marina S Kolesnikova, Maryana V Bardina, Elena V Khitrina, Stanleyson V Hato, Frank J M van Kuppeveld, Vadim I Agol. Interactions between viral and prokaryotic pathogens in a mixed infection with cardiovirus and mycoplasma.
Journal of virology.
2009 Oct; 83(19):9940-51. doi:
10.1128/jvi.01167-09. [PMID: 19605479] - Tessa M Geel, Gregor Meiss, Bernardina T van der Gun, Bart Jan Kroesen, Lou F de Leij, Mindaugas Zaremba, Arūnas Silanskas, Michael Kokkinidis, Alfred Pingoud, Marcel H Ruiters, Pamela M McLaughlin, Marianne G Rots. Endonucleases induced TRAIL-insensitive apoptosis in ovarian carcinoma cells.
Experimental cell research.
2009 Sep; 315(15):2487-95. doi:
10.1016/j.yexcr.2009.06.011. [PMID: 19540229] - Manjari Chaudhari, R Jayaraj, A S B Bhaskar, P V Lakshmana Rao. Oxidative stress induction by T-2 toxin causes DNA damage and triggers apoptosis via caspase pathway in human cervical cancer cells.
Toxicology.
2009 Aug; 262(2):153-61. doi:
10.1016/j.tox.2009.06.002. [PMID: 19524637] - Heitham T Hassoun, Mihaela L Lie, Dmitry N Grigoryev, Manchang Liu, Rubin M Tuder, Hamid Rabb. Kidney ischemia-reperfusion injury induces caspase-dependent pulmonary apoptosis.
American journal of physiology. Renal physiology.
2009 Jul; 297(1):F125-37. doi:
10.1152/ajprenal.90666.2008. [PMID: 19403643] - Gui-Qin Qu, Xiang Liu, Ya-Li Zhang, Dan Yao, Qiu-Min Ma, Ming-Yu Yang, Wen-Hua Zhu, Shi Yu, Yun-Bo Luo. Evidence for programmed cell death and activation of specific caspase-like enzymes in the tomato fruit heat stress response.
Planta.
2009 May; 229(6):1269-79. doi:
10.1007/s00425-009-0908-4. [PMID: 19296126] - Teruyoshi Uetani, Hironao Nakayama, Hideki Okayama, Takafumi Okura, Jitsuo Higaki, Hirofumi Inoue, Shigeki Higashiyama. Insufficiency of pro-heparin-binding epidermal growth factor-like growth factor shedding enhances hypoxic cell death in H9c2 cardiomyoblasts via the activation of caspase-3 and c-Jun N-terminal kinase.
The Journal of biological chemistry.
2009 May; 284(18):12399-409. doi:
10.1074/jbc.m900463200. [PMID: 19193634] - Monika Berns, Margit Toennessen, Petra Koehne, Rodica Altmann, Michael Obladen. Ibuprofen augments bilirubin toxicity in rat cortical neuronal culture.
Pediatric research.
2009 Apr; 65(4):392-6. doi:
10.1203/pdr.0b013e3181991511. [PMID: 19127220] - Byeong-Churl Jang, Jong-Gu Park, Dae-Kyu Song, Won-Ki Baek, Sun Kyun Yoo, Kyung-Hwan Jung, Gy-Young Park, Tae-Yun Lee, Seong-Il Suh. Sanguinarine induces apoptosis in A549 human lung cancer cells primarily via cellular glutathione depletion.
Toxicology in vitro : an international journal published in association with BIBRA.
2009 Mar; 23(2):281-7. doi:
10.1016/j.tiv.2008.12.013. [PMID: 19135517] - Ying-Ying Lu, Tong-Sheng Chen, Jun-Le Qu, Wen-Liang Pan, Lei Sun, Xun-Bin Wei. Dihydroartemisinin (DHA) induces caspase-3-dependent apoptosis in human lung adenocarcinoma ASTC-a-1 cells.
Journal of biomedical science.
2009 Feb; 16(?):16. doi:
10.1186/1423-0127-16-16. [PMID: 19272183] - Ting-Shuan Wu, Yi-Chun Liao, Feng-Yih Yu, Chia-Hao Chang, Biing-Hui Liu. Mechanism of patulin-induced apoptosis in human leukemia cells (HL-60).
Toxicology letters.
2008 Dec; 183(1-3):105-11. doi:
10.1016/j.toxlet.2008.09.018. [PMID: 18992795]