2-hydroxy-3-[6-hydroxy-5-[(E)-4-methyl-6-(2,6,6-trimethylcyclohexen-1-yl)hex-3-enyl]-3,6-dihydro-2H-pyran-2-yl]-2H-furan-5-one (BioDeep_00000912362)
代谢物信息卡片
化学式: C25H36O5 (416.2562606)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(C(CCC1)(C)C)CCC(=CCCC2=CCC(OC2O)C3=CC(=O)OC3O)C
InChI: InChI=1S/C25H36O5/c1-16(10-12-20-17(2)8-6-14-25(20,3)4)7-5-9-18-11-13-21(29-23(18)27)19-15-22(26)30-24(19)28/h7,11,15,21,23-24,27-28H,5-6,8-10,12-14H2,1-4H3/b16-7+
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ming Chen, Chie Aoki-Utsubo, Masanori Kameoka, Lin Deng, Yutaka Terada, Wataru Kamitani, Kei Sato, Yoshio Koyanagi, Makoto Hijikata, Keiko Shindo, Takeshi Noda, Michinori Kohara, Hak Hotta. Broad-spectrum antiviral agents: secreted phospholipase A2 targets viral envelope lipid bilayers derived from the endoplasmic reticulum membrane.
Scientific reports.
2017 Nov; 7(1):15931. doi:
10.1038/s41598-017-16130-w. [PMID: 29162867] - E V Samoilova, A A Pirkova, N V Prokazova, A A Korotaeva. Effect of serum from cardiovascular patients on catalytic activity of secretory phospholipase A2 (IIA).
Bulletin of experimental biology and medicine.
2006 Nov; 142(5):581-2. doi:
10.1007/s10517-006-0423-6. [PMID: 17415467] - Frédéric Dorandeu, Rémi Hesters, Fabien Girard, Elise Four, Annie Foquin, Cassian Bon, Guy Lallement, Grazyna Faure. Inhibition of crotoxin phospholipase A(2) activity by manoalide associated with inactivation of crotoxin toxicity and dissociation of the heterodimeric neurotoxic complex.
Biochemical pharmacology.
2002 Feb; 63(4):755-61. doi:
10.1016/s0006-2952(01)00896-6. [PMID: 11992645] - A Soejima, S Ishizuka, N Miyake, K Fukuoka, M Suzuki, Y Kamiya, T Nagasawa. Simultaneous inhibition of renal phospholipase A(2) and glutathione synthesis by manoalide and DL-buthionine sulfoximine induces acute tubular dysfunction in rats.
Experimental nephrology.
2000 Mar; 8(2):84-90. doi:
10.1159/000020653. [PMID: 10729747] - J Y Miao, S Araki, H W Zhang, H Hayashi. Effect of manoalide on apoptosis induced by deprivation of growth factors in vascular endothelial cells.
Zhongguo yao li xue bao = Acta pharmacologica Sinica.
1999 Feb; 20(2):121-5. doi:
NULL. [PMID: 10437157] - A Pompeo, M Baldassare, A Luini, R Buccione. Cyclosporin A, but not FK506, increases arachidonic acid release and inhibits proliferation of pituitary corticotrope tumor cells.
Life sciences.
1999; 64(10):837-46. doi:
10.1016/s0024-3205(99)00005-3. [PMID: 10096434] - E Grange, O Rabin, J Bell, M C Chang. Manoalide, a phospholipase A2 inhibitor, inhibits arachidonate incorporation and turnover in brain phospholipids of the awake rat.
Neurochemical research.
1998 Oct; 23(10):1251-7. doi:
10.1023/a:1020788031720. [PMID: 9804280] - R D Butcher, S J Wojcik, T Lints, T Wilson, P C Schofield, R Ralph. Arachidonic acid, a growth signal in murine P815 mastocytoma cells.
Cancer research.
1993 Jul; 53(14):3405-10. doi:
NULL. [PMID: 8391926] - S Muallem, P Loessberg, G Sachs, L A Wheeler. Agonist-sensitive and -insensitive intracellular Ca2+ pools. Separate Ca(2+)-releasing mechanisms revealed by manoalide and benzohydroquinone.
The Biochemical journal.
1991 Oct; 279 ( Pt 2)(?):367-75. doi:
10.1042/bj2790367. [PMID: 1659378] - C F Bennett, S Mong, M A Clarke, L I Kruse, S T Crooke. Differential effects of manoalide on secreted and intracellular phospholipases.
Biochemical pharmacology.
1987 Mar; 36(5):733-40. doi:
10.1016/0006-2952(87)90727-1. [PMID: 3103628]