5-[[6-Amino-1-(1-carboxyethylamino)-1-oxohexan-2-yl]amino]-4-[[2-[(2-amino-3-sulfanylpropanoyl)amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-oxopentanoic acid (BioDeep_00000912355)
代谢物信息卡片
化学式: C23H43N9O8S (605.2955)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C(=O)O)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(CS)N
InChI: InChI=1S/C23H43N9O8S/c1-12(22(39)40)29-19(36)14(5-2-3-9-24)31-21(38)16(7-8-17(33)34)32-20(37)15(6-4-10-28-23(26)27)30-18(35)13(25)11-41/h12-16,41H,2-11,24-25H2,1H3,(H,29,36)(H,30,35)(H,31,38)(H,32,37)(H,33,34)(H,39,40)(H4,26,27,28)
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Catherine A Gormley, Benjamin J Keenan, Jo Ann Buczek-Thomas, Amanda C S N Pessoa, Jiang Xu, Fabrice Monti, Patrick Tabeling, R Glynn Holt, Jon O Nagy, Joyce Y Wong. Fibrin-Targeted Polymerized Shell Microbubbles as Potential Theranostic Agents for Surgical Adhesions.
Langmuir : the ACS journal of surfaces and colloids.
2019 08; 35(31):10061-10067. doi:
10.1021/acs.langmuir.8b03692. [PMID: 30681875] - Hui Xiong, Shi Du, Ping Zhang, Zhijie Jiang, Jianping Zhou, Jing Yao. Primary tumor and pre-metastatic niches co-targeting 'peptides-lego' hybrid hydroxyapatite nanoparticles for metastatic breast cancer treatment.
Biomaterials science.
2018 Sep; 6(10):2591-2604. doi:
10.1039/c8bm00706c. [PMID: 30187035] - Anna Puiggalí-Jou, Luis J Del Valle, Carlos Alemán, Maria M Pérez-Madrigal. Weighing biointeractions between fibrin(ogen) and clot-binding peptides using microcantilever sensors.
Journal of peptide science : an official publication of the European Peptide Society.
2017 Feb; 23(2):162-171. doi:
10.1002/psc.2938. [PMID: 27862637] - A Puiggalí-Jou, Luis J Del Valle, Elaine Armelin, Carlos Alemán. Fibrin Association at Hybrid Biointerfaces Made of Clot-Binding Peptides and Polythiophene.
Macromolecular bioscience.
2016 10; 16(10):1461-1474. doi:
10.1002/mabi.201600128. [PMID: 27364985] - Dipti Deshpande, Sravani Kethireddy, David R Janero, Mansoor M Amiji. Therapeutic Efficacy of an ω-3-Fatty Acid-Containing 17-β Estradiol Nano-Delivery System against Experimental Atherosclerosis.
PloS one.
2016; 11(2):e0147337. doi:
10.1371/journal.pone.0147337. [PMID: 26840601] - Chao Wang, Xin Wang, Ting Zhong, Yang Zhao, Wei-Qiang Zhang, Wei Ren, Dan Huang, Shuang Zhang, Yang Guo, Xin Yao, Yi-Qun Tang, Xuan Zhang, Qiang Zhang. The antitumor activity of tumor-homing peptide-modified thermosensitive liposomes containing doxorubicin on MCF-7/ADR: in vitro and in vivo.
International journal of nanomedicine.
2015; 10(?):2229-48. doi:
10.2147/ijn.s79840. [PMID: 25834435] - Apurva R Patel, Mahavir B Chougule, Ed Lim, Kevin P Francis, Stephen Safe, Mandip Singh. Theranostic tumor homing nanocarriers for the treatment of lung cancer.
Nanomedicine : nanotechnology, biology, and medicine.
2014 Jul; 10(5):1053-63. doi:
10.1016/j.nano.2013.12.002. [PMID: 24355163] - Anastasia M Kruse, Samantha A Meenach, Kimberly W Anderson, J Zach Hilt. Synthesis and characterization of CREKA-conjugated iron oxide nanoparticles for hyperthermia applications.
Acta biomaterialia.
2014 Jun; 10(6):2622-9. doi:
10.1016/j.actbio.2014.01.025. [PMID: 24486913] - Dipti Deshpande, Sravani Kethireddy, Florence Gattacceca, Mansoor Amiji. Comparative pharmacokinetics and tissue distribution analysis of systemically administered 17-β-estradiol and its metabolites in vivo delivered using a cationic nanoemulsion or a peptide-modified nanoemulsion system for targeting atherosclerosis.
Journal of controlled release : official journal of the Controlled Release Society.
2014 Apr; 180(?):117-24. doi:
10.1016/j.jconrel.2014.02.009. [PMID: 24556419] - David Zanuy, Francisco J Sayago, Guillem Revilla-López, Gema Ballano, Lilach Agemy, Venkata Ramana Kotamraju, Ana I Jiménez, Carlos Cativiela, Ruth Nussinov, April M Sawvel, Galen Stucky, Erkki Ruoslahti, Carlos Alemán. Engineering strategy to improve peptide analogs: from structure-based computational design to tumor homing.
Journal of computer-aided molecular design.
2013 Jan; 27(1):31-43. doi:
10.1007/s10822-012-9623-5. [PMID: 23239171] - David Curcó, David Zanuy, Ruth Nussinov, Carlos Alemán. A simulation strategy for the atomistic modeling of flexible molecules covalently tethered to rigid surfaces: application to peptides.
Journal of computational chemistry.
2011 Mar; 32(4):607-19. doi:
10.1002/jcc.21647. [PMID: 20806264] - Lilach Agemy, Kazuki N Sugahara, Venkata Ramana Kotamraju, Kunal Gujraty, Olivier M Girard, Yuko Kono, Robert F Mattrey, Ji-Ho Park, Michael J Sailor, Ana I Jimenez, Carlos Cativiela, David Zanuy, Francisco J Sayago, Carlos Aleman, Ruth Nussinov, Erkki Ruoslahti. Nanoparticle-induced vascular blockade in human prostate cancer.
Blood.
2010 Oct; 116(15):2847-56. doi:
10.1182/blood-2010-03-274258. [PMID: 20587786]
