(17Z,19E,21E,23E,25E)-3-hexyl-4,6,8,10,12,14,16,27-octahydroxy-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one (BioDeep_00000912301)
代谢物信息卡片
(17Z,19E,21E,23E,25E)-3-hexyl-4,6,8,10,12,14,16,27-octahydroxy-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one
化学式: C35H58O10 (638.403)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCC1C(CC(CC(CC(CC(CC(CC(C(=CC=CC=CC=CC=CC(C(OC1=O)C)O)C)O)O)O)O)O)O)O
InChI: InChI=1S/C35H58O10/c1-4-5-6-13-16-31-34(43)23-30(40)21-28(38)19-26(36)18-27(37)20-29(39)22-33(42)24(2)15-12-10-8-7-9-11-14-17-32(41)25(3)45-35(31)44/h7-12,14-15,17,25-34,36-43H,4-6,13,16,18-23H2,1-3H3/b8-7+,11-9+,12-10+,17-14+,24-15-
描述信息
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
D000890 - Anti-Infective Agents > D000935 - Antifungal Agents
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Lilian N D Silva, Israel J P Garcia, Jessica M M Valadares, Marco Tulio C Pessoa, Marina Marques Toledo, Matheus V Machado, Mileane Souza Busch, Isabella Rocha, José Augusto F P Villar, Georgia C Atella, Herica L Santos, Vanessa F Cortes, Leandro A Barbosa. Evaluation of Cardiotonic Steroid Modulation of Cellular Cholesterol and Phospholipid.
The Journal of membrane biology.
2021 12; 254(5-6):499-512. doi:
10.1007/s00232-021-00203-z. [PMID: 34716469] - Cátia Santos-Pereira, María T Andrés, Susana R Chaves, José F Fierro, Hernâni Gerós, Stéphen Manon, Lígia R Rodrigues, Manuela Côrte-Real. Lactoferrin perturbs lipid rafts and requires integrity of Pma1p-lipid rafts association to exert its antifungal activity against Saccharomyces cerevisiae.
International journal of biological macromolecules.
2021 Feb; 171(?):343-357. doi:
10.1016/j.ijbiomac.2020.12.224. [PMID: 33421469] - Lita A Freeman, Robert D Shamburek, Maureen L Sampson, Edward B Neufeld, Masaki Sato, Sotirios K Karathanasis, Alan T Remaley. Plasma lipoprotein-X quantification on filipin-stained gels: monitoring recombinant LCAT treatment ex vivo.
Journal of lipid research.
2019 05; 60(5):1050-1057. doi:
10.1194/jlr.d090233. [PMID: 30808683] - Léa P Wilhelm, Laetitia Voilquin, Toshihide Kobayashi, Catherine Tomasetto, Fabien Alpy. Intracellular and Plasma Membrane Cholesterol Labeling and Quantification Using Filipin and GFP-D4.
Methods in molecular biology (Clifton, N.J.).
2019; 1949(?):137-152. doi:
10.1007/978-1-4939-9136-5_11. [PMID: 30790254] - Kirsty E Waddington, Inés Pineda-Torra, Elizabeth C Jury. Analyzing T-Cell Plasma Membrane Lipids by Flow Cytometry.
Methods in molecular biology (Clifton, N.J.).
2019; 1951(?):209-216. doi:
10.1007/978-1-4939-9130-3_16. [PMID: 30825155] - Hao Wei, Jean-Daniel M Malcor, Matthew T Harper. Lipid rafts are essential for release of phosphatidylserine-exposing extracellular vesicles from platelets.
Scientific reports.
2018 07; 8(1):9987. doi:
10.1038/s41598-018-28363-4. [PMID: 29968812] - Emily K Pugach, McKenna Feltes, Randal J Kaufman, Daniel S Ory, Anne G Bang. High-content screen for modifiers of Niemann-Pick type C disease in patient cells.
Human molecular genetics.
2018 06; 27(12):2101-2112. doi:
10.1093/hmg/ddy117. [PMID: 29659804] - Wenmin Yu, Zhi Wang, Yiping Li, Lei Liu, Jing Liu, Fenggan Ding, Xiaoyi Zhang, Zhengyuan Cheng, Pingsheng Chen. Effects of autophagy and endocytosis on the activity of matrix metalloproteinase‑2 in human renal proximal tubular cells under hypoxia.
Molecular medicine reports.
2017 May; 15(5):3225-3230. doi:
10.3892/mmr.2017.6358. [PMID: 28339082] - Isabel De Castro-Orós, Pilar Irún, Jorge Javier Cebolla, Victor Rodriguez-Sureda, Miguel Mallén, María Jesús Pueyo, Pilar Mozas, Carmen Dominguez, Miguel Pocoví. Assessment of plasma chitotriosidase activity, CCL18/PARC concentration and NP-C suspicion index in the diagnosis of Niemann-Pick disease type C: a prospective observational study.
Journal of translational medicine.
2017 02; 15(1):43. doi:
10.1186/s12967-017-1146-3. [PMID: 28222799] - Rachid Rezgui, Katy Blumer, Gilbert Yeoh-Tan, Adam J Trexler, Mazin Magzoub. Precise quantification of cellular uptake of cell-penetrating peptides using fluorescence-activated cell sorting and fluorescence correlation spectroscopy.
Biochimica et biophysica acta.
2016 Jul; 1858(7 Pt A):1499-506. doi:
10.1016/j.bbamem.2016.03.023. [PMID: 27033412] - Kaoutar El-Mounadi, Kazi T Islam, Patricia Hernández-Ortiz, Nick D Read, Dilip M Shah. Antifungal mechanisms of a plant defensin MtDef4 are not conserved between the ascomycete fungi Neurospora crassa and Fusarium graminearum.
Molecular microbiology.
2016 05; 100(3):542-59. doi:
10.1111/mmi.13333. [PMID: 26801962] - Hao Wang, Weisha Liu, Fei Yu, Liqun Lu. Disruption of clathrin-dependent trafficking results in the failure of grass carp reovirus cellular entry.
Virology journal.
2016 Feb; 13(?):25. doi:
10.1186/s12985-016-0485-7. [PMID: 26878859] - Marie T Vanier, Philippe Latour. Laboratory diagnosis of Niemann-Pick disease type C: the filipin staining test.
Methods in cell biology.
2015; 126(?):357-75. doi:
10.1016/bs.mcb.2014.10.028. [PMID: 25665455] - Carolina Piña-Vázquez, Magda Reyes-López, Guillermo Mendoza-Hernández, Rosa María Bermúdez-Cruz, Mireya de la Garza. Identification of phosphatidylcholine transfer protein-like in the parasite Entamoeba histolytica.
Biochimie.
2014 Dec; 107 Pt B(?):223-34. doi:
10.1016/j.biochi.2014.09.007. [PMID: 25223890] - Sayaka Nagasawa, Kohei Ogura, Hiroyasu Tsutsuki, Hisako Saitoh, Joel Moss, Hirotaro Iwase, Masatoshi Noda, Kinnosuke Yahiro. Uptake of Shiga-toxigenic Escherichia coli SubAB by HeLa cells requires an actin- and lipid raft-dependent pathway.
Cellular microbiology.
2014 Oct; 16(10):1582-601. doi:
10.1111/cmi.12315. [PMID: 24844382] - Leah K Cuddy, Warren Winick-Ng, Rebecca Jane Rylett. Regulation of the high-affinity choline transporter activity and trafficking by its association with cholesterol-rich lipid rafts.
Journal of neurochemistry.
2014 Mar; 128(5):725-40. doi:
10.1111/jnc.12490. [PMID: 24127780] - Karla Dias Cruz, Thayana Araújo Cruz, Gabriela Veras de Moraes, Tatiana Christina Paredes-Santos, Marcia Attias, Wanderley de Souza. Disruption of lipid rafts interferes with the interaction of Toxoplasma gondii with macrophages and epithelial cells.
BioMed research international.
2014; 2014(?):687835. doi:
10.1155/2014/687835. [PMID: 24734239] - Ludmila A Kasatkina, Tatiana A Borisova. Glutamate release from platelets: exocytosis versus glutamate transporter reversal.
The international journal of biochemistry & cell biology.
2013 Nov; 45(11):2585-95. doi:
10.1016/j.biocel.2013.08.004. [PMID: 23994539] - M I Arleevskaya, A I Zabotin, A G Gabdulkhakova, O M Semenova, A P Tsibulkin. Lipid imbalance in individuals predisposed to rheumatoid arthritis: possible relationship with common infections.
Bulletin of experimental biology and medicine.
2013 Oct; 155(6):778-84. doi:
10.1007/s10517-013-2251-9. [PMID: 24288765] - Patrycja Kozik, Nicola A Hodson, Daniela A Sahlender, Nikol Simecek, Christina Soromani, Jiahua Wu, Lucy M Collinson, Margaret S Robinson. A human genome-wide screen for regulators of clathrin-coated vesicle formation reveals an unexpected role for the V-ATPase.
Nature cell biology.
2013 Jan; 15(1):50-60. doi:
10.1038/ncb2652. [PMID: 23263279] - Elina Siljamäki, Nina Rintanen, Maija Kirsi, Paula Upla, Wei Wang, Mikko Karjalainen, Elina Ikonen, Varpu Marjomäki. Cholesterol dependence of collagen and echovirus 1 trafficking along the novel α2β1 integrin internalization pathway.
PloS one.
2013; 8(2):e55465. doi:
10.1371/journal.pone.0055465. [PMID: 23393580] - Oren Moskovich, Lee-Or Herzog, Marcelo Ehrlich, Zvi Fishelson. Caveolin-1 and dynamin-2 are essential for removal of the complement C5b-9 complex via endocytosis.
The Journal of biological chemistry.
2012 Jun; 287(24):19904-15. doi:
10.1074/jbc.m111.333039. [PMID: 22528500] - Jiangli Dou, Lianwan Chen, Youqiao Hu, Long Miao. Cholesterol and the biosynthesis of glycosphingolipids are required for sperm activation in Caenorhabditis elegans.
Biochimica et biophysica acta.
2012 Jun; 1821(6):934-42. doi:
10.1016/j.bbalip.2012.03.005. [PMID: 22484621] - Anke S Klein, Michael Schaefer, Thomas Korte, Andreas Herrmann, Astrid Tannert. HaCaT keratinocytes exhibit a cholesterol and plasma membrane viscosity gradient during directed migration.
Experimental cell research.
2012 Apr; 318(7):809-18. doi:
10.1016/j.yexcr.2012.02.007. [PMID: 22366262] - Min Long, Sheng-He Huang, Chun-Hua Wu, Gregory M Shackleford, Ambrose Jong. Lipid raft/caveolae signaling is required for Cryptococcus neoformans invasion into human brain microvascular endothelial cells.
Journal of biomedical science.
2012 Feb; 19(?):19. doi:
10.1186/1423-0127-19-19. [PMID: 22316086] - T N Efremova, V I Chubinskiĭ-Nadezhdin, S Iu Khaĭtlina, E A Morachevskaia. [Assembly of actin filaments induced by sequestration of membrane cholesterol in transformed cells].
Tsitologiia.
2012; 54(6):508-14. doi:
NULL. [PMID: 22997736] - Kari Fine-Coulson, Barbara J Reaves, Russell K Karls, Frederick D Quinn. The role of lipid raft aggregation in the infection of type II pneumocytes by Mycobacterium tuberculosis.
PloS one.
2012; 7(9):e45028. doi:
10.1371/journal.pone.0045028. [PMID: 23024786] - Didier Colin, Emeric Limagne, Sylvie Jeanningros, Arnaud Jacquel, Gérard Lizard, Anne Athias, Philippe Gambert, Aziz Hichami, Norbert Latruffe, Eric Solary, Dominique Delmas. Endocytosis of resveratrol via lipid rafts and activation of downstream signaling pathways in cancer cells.
Cancer prevention research (Philadelphia, Pa.).
2011 Jul; 4(7):1095-106. doi:
10.1158/1940-6207.capr-10-0274. [PMID: 21467134] - Julian R Arthur, Karie A Heinecke, Thomas N Seyfried. Filipin recognizes both GM1 and cholesterol in GM1 gangliosidosis mouse brain.
Journal of lipid research.
2011 Jul; 52(7):1345-51. doi:
10.1194/jlr.m012633. [PMID: 21508255] - A V Tamashevskiĭ, N M Kozlova, N V Goncharova, G P Zubritskaia, E I Slobozhanina. [Effect of cholesterol on the functional activity of proteins responsible for the resistance of human lymphocytes to xenobiotics].
Biofizika.
2011 May; 56(3):455-64. doi:
NULL. [PMID: 21786699] - Carolina Tängemo, Dominik Weber, Susanne Theiss, Eugen Mengel, Heiko Runz. Niemann-Pick Type C disease: characterizing lipid levels in patients with variant lysosomal cholesterol storage.
Journal of lipid research.
2011 Apr; 52(4):813-25. doi:
10.1194/jlr.p013524. [PMID: 21245028] - Zhen-Huan Wang, Qing-Hua Hu, Hua Zhong, Feng-Mei Deng, Fang He. [Extracellular Ca(2+)-sensing receptor-induced extracellular Ca2+ influx is down-regulated by caveolin-1 in human umbilical vein endothelial cells].
Sheng li xue bao : [Acta physiologica Sinica].
2011 Feb; 63(1):39-47. doi:
NULL. [PMID: 21340433] - Gustavo R Ares, Pablo A Ortiz. Constitutive endocytosis and recycling of NKCC2 in rat thick ascending limbs.
American journal of physiology. Renal physiology.
2010 Nov; 299(5):F1193-202. doi:
10.1152/ajprenal.00307.2010. [PMID: 20719977] - Laurent Bonneau, Patricia Gerbeau-Pissot, Dominique Thomas, Christophe Der, Jeannine Lherminier, Stéphane Bourque, Yann Roche, Françoise Simon-Plas. Plasma membrane sterol complexation, generated by filipin, triggers signaling responses in tobacco cells.
Biochimica et biophysica acta.
2010 Nov; 1798(11):2150-9. doi:
10.1016/j.bbamem.2010.07.026. [PMID: 20674542] - Miroslav Ovecka, Tobias Berson, Martina Beck, Jan Derksen, Jozef Samaj, Frantisek Baluska, Irene K Lichtscheidl. Structural sterols are involved in both the initiation and tip growth of root hairs in Arabidopsis thaliana.
The Plant cell.
2010 Sep; 22(9):2999-3019. doi:
10.1105/tpc.109.069880. [PMID: 20841426] - Anne Auriac, Alexandra Willemetz, François Canonne-Hergaux. Lipid raft-dependent endocytosis: a new route for hepcidin-mediated regulation of ferroportin in macrophages.
Haematologica.
2010 Aug; 95(8):1269-77. doi:
10.3324/haematol.2009.019992. [PMID: 20220061] - Yvonne Maria te Welscher, Lynden Jones, Martin Richard van Leeuwen, Jan Dijksterhuis, Ben de Kruijff, Gary Eitzen, Eefjan Breukink. Natamycin inhibits vacuole fusion at the priming phase via a specific interaction with ergosterol.
Antimicrobial agents and chemotherapy.
2010 Jun; 54(6):2618-25. doi:
10.1128/aac.01794-09. [PMID: 20385867] - Florian Spörl, Minetta Wunderskirchner, Oliver Ullrich, Gerrit Bömke, Ute Breitenbach, Thomas Blatt, Horst Wenck, Klaus-Peter Wittern, Annika Schrader. Real-time monitoring of membrane cholesterol reveals new insights into epidermal differentiation.
The Journal of investigative dermatology.
2010 May; 130(5):1268-78. doi:
10.1038/jid.2009.412. [PMID: 20043016] - Gerald Gimpl. Cholesterol-protein interaction: methods and cholesterol reporter molecules.
Sub-cellular biochemistry.
2010; 51(?):1-45. doi:
10.1007/978-90-481-8622-8_1. [PMID: 20213539] - Mattia Di Nunzio, Diederik van Deursen, Adrie J M Verhoeven, Alessandra Bordoni. n-3 and n-6 Polyunsaturated fatty acids suppress sterol regulatory element binding protein activity and increase flow of non-esterified cholesterol in HepG2 cells.
The British journal of nutrition.
2010 Jan; 103(2):161-7. doi:
10.1017/s000711450999167x. [PMID: 19825216] - Laura Milan-Lobo, Ingrid Gsandtner, Erwin Gaubitzer, Dominik Rünzler, Florian Buchmayer, Gottfried Köhler, Antonello Bonci, Michael Freissmuth, Harald H Sitte. Subtype-specific differences in corticotropin-releasing factor receptor complexes detected by fluorescence spectroscopy.
Molecular pharmacology.
2009 Dec; 76(6):1196-210. doi:
10.1124/mol.109.059139. [PMID: 19755522] - Peng Liu, Rui-Li Li, Liang Zhang, Qin-Li Wang, Karsten Niehaus, Frantisek Baluska, Jozef Samaj, Jin-Xing Lin. Lipid microdomain polarization is required for NADPH oxidase-dependent ROS signaling in Picea meyeri pollen tube tip growth.
The Plant journal : for cell and molecular biology.
2009 Oct; 60(2):303-13. doi:
10.1111/j.1365-313x.2009.03955.x. [PMID: 19566595] - Lois M Douglas, Stephen W Martin, James B Konopka. BAR domain proteins Rvs161 and Rvs167 contribute to Candida albicans endocytosis, morphogenesis, and virulence.
Infection and immunity.
2009 Sep; 77(9):4150-60. doi:
10.1128/iai.00683-09. [PMID: 19596778] - Cathryn L Haigh, Victoria A Lewis, Laura J Vella, Colin L Masters, Andrew F Hill, Victoria A Lawson, Steven J Collins. PrPC-related signal transduction is influenced by copper, membrane integrity and the alpha cleavage site.
Cell research.
2009 Sep; 19(9):1062-78. doi:
10.1038/cr.2009.86. [PMID: 19597535] - M R Van Leeuwen, E A Golovina, J Dijksterhuis. The polyene antimycotics nystatin and filipin disrupt the plasma membrane, whereas natamycin inhibits endocytosis in germinating conidia of Penicillium discolor.
Journal of applied microbiology.
2009 Jun; 106(6):1908-18. doi:
10.1111/j.1365-2672.2009.04165.x. [PMID: 19228256] - Ruth Knorr, Claudia Karacsonyi, Robert Lindner. Endocytosis of MHC molecules by distinct membrane rafts.
Journal of cell science.
2009 May; 122(Pt 10):1584-94. doi:
10.1242/jcs.039727. [PMID: 19383725] - Julia E Maxson, Caroline A Enns, An-Sheng Zhang. Processing of hemojuvelin requires retrograde trafficking to the Golgi in HepG2 cells.
Blood.
2009 Feb; 113(8):1786-93. doi:
10.1182/blood-2008-08-174565. [PMID: 19029439] - Yu Ishima, Takaaki Akaike, Ulrich Kragh-Hansen, Shuichi Hiroyama, Tomohiro Sawa, Ayaka Suenaga, Toru Maruyama, Toshiya Kai, Masaki Otagiri. S-nitrosylated human serum albumin-mediated cytoprotective activity is enhanced by fatty acid binding.
The Journal of biological chemistry.
2008 Dec; 283(50):34966-75. doi:
10.1074/jbc.m807009200. [PMID: 18940810] - Andreas Klima, Ilse Foissner. FM dyes label sterol-rich plasma membrane domains and are internalized independently of the cytoskeleton in characean internodal cells.
Plant & cell physiology.
2008 Oct; 49(10):1508-21. doi:
10.1093/pcp/pcn122. [PMID: 18757863] - M R Van Leeuwen, W Smant, W de Boer, J Dijksterhuis. Filipin is a reliable in situ marker of ergosterol in the plasma membrane of germinating conidia (spores) of Penicillium discolor and stains intensively at the site of germ tube formation.
Journal of microbiological methods.
2008 Aug; 74(2-3):64-73. doi:
10.1016/j.mimet.2008.04.001. [PMID: 18485505] - Yvonne M te Welscher, Hendrik H ten Napel, Miriam Masià Balagué, Cleiton M Souza, Howard Riezman, Ben de Kruijff, Eefjan Breukink. Natamycin blocks fungal growth by binding specifically to ergosterol without permeabilizing the membrane.
The Journal of biological chemistry.
2008 Mar; 283(10):6393-401. doi:
10.1074/jbc.m707821200. [PMID: 18165687] - Kelly M Kitchens, Rohit B Kolhatkar, Peter W Swaan, Hamidreza Ghandehari. Endocytosis inhibitors prevent poly(amidoamine) dendrimer internalization and permeability across Caco-2 cells.
Molecular pharmaceutics.
2008 Mar; 5(2):364-9. doi:
10.1021/mp700089s. [PMID: 18173246] - Kirsi Harila, Antti Salminen, Ian Prior, Jorma Hinkula, Maarit Suomalainen. The Vpu-regulated endocytosis of HIV-1 Gag is clathrin-independent.
Virology.
2007 Dec; 369(2):299-308. doi:
10.1016/j.virol.2007.08.009. [PMID: 17822732] - Gerald Gimpl, Katja Gehrig-Burger. Cholesterol reporter molecules.
Bioscience reports.
2007 Dec; 27(6):335-58. doi:
10.1007/s10540-007-9060-1. [PMID: 17668316] - Saotomo Itoh, Chie Susuki, Kana Takeshita, Kisaburo Nagata, Tsutomu Tsuji. Redistribution of P-selectin glycoprotein ligand-1 (PSGL-1) in chemokine-treated neutrophils: a role of lipid microdomains.
Journal of leukocyte biology.
2007 Jun; 81(6):1414-21. doi:
10.1189/jlb.0606398. [PMID: 17372146] - Patricia G Yancey, W Gray Jerome, Hong Yu, Evelyn E Griffin, Brian E Cox, Vladimir R Babaev, Sergio Fazio, MacRae F Linton. Severely altered cholesterol homeostasis in macrophages lacking apoE and SR-BI.
Journal of lipid research.
2007 May; 48(5):1140-9. doi:
10.1194/jlr.m600539-jlr200. [PMID: 17299204] - Isabelle Delton-Vandenbroucke, Jerome Bouvier, Asami Makino, Nelly Besson, Jean-François Pageaux, Michel Lagarde, Toshihide Kobayashi. Anti-bis(monoacylglycero)phosphate antibody accumulates acetylated LDL-derived cholesterol in cultured macrophages.
Journal of lipid research.
2007 Mar; 48(3):543-52. doi:
10.1194/jlr.m600266-jlr200. [PMID: 17146116] - Hana Mahmutefendić, Gordana Blagojević, Natalia Kucić, Pero Lucin. Constitutive internalization of murine MHC class I molecules.
Journal of cellular physiology.
2007 Feb; 210(2):445-55. doi:
10.1002/jcp.20877. [PMID: 17044074] - Kimberly A Petro, Maureen A Dyer, Brian C Yowler, Cara-Lynne Schengrund. Disruption of lipid rafts enhances activity of botulinum neurotoxin serotype A.
Toxicon : official journal of the International Society on Toxinology.
2006 Dec; 48(8):1035-45. doi:
10.1016/j.toxicon.2006.08.011. [PMID: 17046039] - Eriko Takahashi, Osamu Inanami, Toshio Ohta, Akira Matsuda, Mikinori Kuwabara. Lipid raft disruption prevents apoptosis induced by 2-chloro-2'-deoxyadenosine (Cladribine) in leukemia cell lines.
Leukemia research.
2006 Dec; 30(12):1555-61. doi:
10.1016/j.leukres.2006.04.008. [PMID: 16730061] - Joan Villena, Jessica Mainez, Oriol Noguer, Héctor Contreras, Francesc Granés, Manuel Reina, Isabel Fabregat, Senén Vilaró. Syndecan-2 expression increases serum-withdrawal-induced apoptosis, mediated by re-distribution of Fas into lipid rafts, in stably transfected Swiss 3T3 cells.
Apoptosis : an international journal on programmed cell death.
2006 Nov; 11(11):2065-75. doi:
10.1007/s10495-006-0193-7. [PMID: 17041758] - Naoka Yamamoto, Nobutaka Yamamoto, Matthew W Petroll, James V Jester, H Dwight Cavanagh. Regulation of Pseudomonas aeruginosa internalization after contact lens wear in vivo and in serum-free culture by ocular surface cells.
Investigative ophthalmology & visual science.
2006 Aug; 47(8):3430-40. doi:
10.1167/iovs.05-1332. [PMID: 16877413] - Volker Wachtler, Mohan K Balasubramanian. Yeast lipid rafts?--an emerging view.
Trends in cell biology.
2006 Jan; 16(1):1-4. doi:
10.1016/j.tcb.2005.11.008. [PMID: 16337381] - Lilia Leisle, Edward T Parkin, Anthony J Turner, Nigel M Hooper. Angiotensin-converting enzyme as a GPIase: a critical reevaluation.
Nature medicine.
2005 Nov; 11(11):1139-40. doi:
10.1038/nm1105-1139. [PMID: 16270062] - Jameel Inal, Sylvie Miot, Jürg A Schifferli. The complement inhibitor, CRIT, undergoes clathrin-dependent endocytosis.
Experimental cell research.
2005 Oct; 310(1):54-65. doi:
10.1016/j.yexcr.2005.07.003. [PMID: 16112669] - Sudhir Jain, Yanna Li, Ashok Kumar, Pravin B Sehgal. Transcriptional signaling from membrane raft-associated glucocorticoid receptor.
Biochemical and biophysical research communications.
2005 Oct; 336(1):3-8. doi:
10.1016/j.bbrc.2005.08.057. [PMID: 16125141] - Timothy J Self, Sarah M Oakley, Stephen J Hill. Clathrin-independent internalization of the human histamine H1-receptor in CHO-K1 cells.
British journal of pharmacology.
2005 Oct; 146(4):612-24. doi:
10.1038/sj.bjp.0706337. [PMID: 16086035] - Tetsuya Takeda, Fred Chang. Role of fission yeast myosin I in organization of sterol-rich membrane domains.
Current biology : CB.
2005 Jul; 15(14):1331-6. doi:
10.1016/j.cub.2005.07.009. [PMID: 16051179] - Agathi Papanikolaou, Alexandra Papafotika, Carol Murphy, Thomais Papamarcaki, Orestes Tsolas, Marek Drab, Teymuras V Kurzchalia, Michael Kasper, Savvas Christoforidis. Cholesterol-dependent lipid assemblies regulate the activity of the ecto-nucleotidase CD39.
The Journal of biological chemistry.
2005 Jul; 280(28):26406-14. doi:
10.1074/jbc.m413927200. [PMID: 15890655] - Jennica L Zaro, Wei-Chiang Shen. Evidence that membrane transduction of oligoarginine does not require vesicle formation.
Experimental cell research.
2005 Jul; 307(1):164-73. doi:
10.1016/j.yexcr.2005.02.024. [PMID: 15922736] - Bo Bang, Robert Gniadecki, Barbara Gajkowska. Disruption of lipid rafts causes apoptotic cell death in HaCaT keratinocytes.
Experimental dermatology.
2005 Apr; 14(4):266-72. doi:
10.1111/j.0906-6705.2005.00283.x. [PMID: 15810884] - Qun Wang, Alicia Turlington, Stephan Heo, Andrea Blanco, Jian Tian, Zijia Xie, Bingfang Yan, Yinsheng Wan. Extracellular matrix activity and caveolae events contribute to cell surface receptor activation that leads to MAP kinase activation in response to UV irradiation in cultured human keratinocytes.
International journal of molecular medicine.
2005 Apr; 15(4):633-40. doi:
10.3892/ijmm.15.4.633. [PMID: 15754025] - Sylvette Chasserot-Golaz, Nicolas Vitale, Emeline Umbrecht-Jenck, Derek Knight, Volker Gerke, Marie-France Bader. Annexin 2 promotes the formation of lipid microdomains required for calcium-regulated exocytosis of dense-core vesicles.
Molecular biology of the cell.
2005 Mar; 16(3):1108-19. doi:
10.1091/mbc.e04-07-0627. [PMID: 15635098] - R A Deisz, V Meske, S Treiber-Held, F Albert, T G Ohm. Pathological cholesterol metabolism fails to modify electrophysiological properties of afflicted neurones in Niemann-Pick disease type C.
Neuroscience.
2005; 130(4):867-73. doi:
10.1016/j.neuroscience.2004.09.065. [PMID: 15652985] - Rebecca S Lam, Andrew R Shaw, Marek Duszyk. Membrane cholesterol content modulates activation of BK channels in colonic epithelia.
Biochimica et biophysica acta.
2004 Dec; 1667(2):241-8. doi:
10.1016/j.bbamem.2004.11.004. [PMID: 15581861] - Paiboon Reungpatthanaphong, Carole Marbeuf-Gueye, Laurence Le Moyec, Milena Salerno, Arlette Garnier-Suillerot. Decrease of P-glycoprotein activity in K562/ADR cells by MbetaCD and filipin and lack of effect induced by cholesterol oxidase indicate that this transporter is not located in rafts.
Journal of bioenergetics and biomembranes.
2004 Dec; 36(6):533-43. doi:
10.1007/s10863-004-9000-8. [PMID: 15692732] - Kunihiko Iwamoto, Shingo Kobayashi, Ryouichi Fukuda, Masato Umeda, Toshihide Kobayashi, Akinori Ohta. Local exposure of phosphatidylethanolamine on the yeast plasma membrane is implicated in cell polarity.
Genes to cells : devoted to molecular & cellular mechanisms.
2004 Oct; 9(10):891-903. doi:
10.1111/j.1365-2443.2004.00782.x. [PMID: 15461661] - Naava Naslavsky, Roberto Weigert, Julie G Donaldson. Characterization of a nonclathrin endocytic pathway: membrane cargo and lipid requirements.
Molecular biology of the cell.
2004 Aug; 15(8):3542-52. doi:
10.1091/mbc.e04-02-0151. [PMID: 15146059] - Robert Gniadecki. Depletion of membrane cholesterol causes ligand-independent activation of Fas and apoptosis.
Biochemical and biophysical research communications.
2004 Jul; 320(1):165-9. doi:
10.1016/j.bbrc.2004.05.145. [PMID: 15207716] - Stephen W Martin, James B Konopka. Lipid raft polarization contributes to hyphal growth in Candida albicans.
Eukaryotic cell.
2004 Jun; 3(3):675-84. doi:
10.1128/ec.3.3.675-684.2004. [PMID: 15189988] - Claudio Frank, Anna Maria Giammarioli, Rita Pepponi, Carla Fiorentini, Stefano Rufini. Cholesterol perturbing agents inhibit NMDA-dependent calcium influx in rat hippocampal primary culture.
FEBS letters.
2004 May; 566(1-3):25-9. doi:
10.1016/j.febslet.2004.03.113. [PMID: 15147862] - Carmine Guirland, Shingo Suzuki, Masami Kojima, Bai Lu, James Q Zheng. Lipid rafts mediate chemotropic guidance of nerve growth cones.
Neuron.
2004 Apr; 42(1):51-62. doi:
10.1016/s0896-6273(04)00157-6. [PMID: 15066264] - Jeffrey T Ferraro, Mani Daneshmand, Rena Bizios, Victor Rizzo. Depletion of plasma membrane cholesterol dampens hydrostatic pressure and shear stress-induced mechanotransduction pathways in osteoblast cultures.
American journal of physiology. Cell physiology.
2004 Apr; 286(4):C831-9. doi:
10.1152/ajpcell.00224.2003. [PMID: 14644772] - Bastian von Tresckow, Karl-Josef Kallen, Elke Pogge von Strandmann, Peter Borchmann, Hans Lange, Andreas Engert, Hinrich P Hansen. Depletion of cellular cholesterol and lipid rafts increases shedding of CD30.
Journal of immunology (Baltimore, Md. : 1950).
2004 Apr; 172(7):4324-31. doi:
10.4049/jimmunol.172.7.4324. [PMID: 15034047] - Wei-Yi Ong, Benny Tan, Ning Pan, Andrew Jenner, Matthew Whiteman, Choon-Nam Ong, Frank Watt, Barry Halliwell. Increased iron staining in the cerebral cortex of cholesterol fed rabbits.
Mechanisms of ageing and development.
2004 Apr; 125(4):305-13. doi:
10.1016/j.mad.2004.01.008. [PMID: 15063107] - Jayoung Kim, Rosalyn M Adam, Keith R Solomon, Michael R Freeman. Involvement of cholesterol-rich lipid rafts in interleukin-6-induced neuroendocrine differentiation of LNCaP prostate cancer cells.
Endocrinology.
2004 Feb; 145(2):613-9. doi:
10.1210/en.2003-0772. [PMID: 14563701] - Robert G Sitrin, Douglas R Johnson, Pauline M Pan, Donna M Harsh, Jibiao Huang, Howard R Petty, R Alexander Blackwood. Lipid raft compartmentalization of urokinase receptor signaling in human neutrophils.
American journal of respiratory cell and molecular biology.
2004 Feb; 30(2):233-41. doi:
10.1165/rcmb.2003-0079oc. [PMID: 12933356] - Isabel Nunes-Correia, Ana Eulálio, Shlomo Nir, Maria C Pedroso de Lima. Caveolae as an additional route for influenza virus endocytosis in MDCK cells.
Cellular & molecular biology letters.
2004; 9(1):47-60. doi:
NULL. [PMID: 15048150] - Diego G Espinosa-Heidmann, John Sall, Eleut P Hernandez, Scott W Cousins. Basal laminar deposit formation in APO B100 transgenic mice: complex interactions between dietary fat, blue light, and vitamin E.
Investigative ophthalmology & visual science.
2004 Jan; 45(1):260-6. doi:
10.1167/iovs.03-0910. [PMID: 14691182] - Mangala Rao, Kristina K Peachman, Carl R Alving, Stephen W Rothwell. Depletion of cellular cholesterol interferes with intracellular trafficking of liposome-encapsulated ovalbumin.
Immunology and cell biology.
2003 Dec; 81(6):415-23. doi:
10.1046/j.1440-1711.2003.01192.x. [PMID: 14636238] - Hyun Soon Lee, Howard S Kruth. Accumulation of cholesterol in the lesions of focal segmental glomerulosclerosis.
Nephrology (Carlton, Vic.).
2003 Oct; 8(5):224-3. doi:
10.1046/j.1440-1797.2003.00160.x. [PMID: 15012708] - Isabelle Coppens, Keith A Joiner. Host but not parasite cholesterol controls Toxoplasma cell entry by modulating organelle discharge.
Molecular biology of the cell.
2003 Sep; 14(9):3804-20. doi:
10.1091/mbc.e02-12-0830. [PMID: 12972565] - Edward T Parkin, Fulong Tan, Randal A Skidgel, Anthony J Turner, Nigel M Hooper. The ectodomain shedding of angiotensin-converting enzyme is independent of its localisation in lipid rafts.
Journal of cell science.
2003 Aug; 116(Pt 15):3079-87. doi:
10.1242/jcs.00626. [PMID: 12799421] - Steven L Parker, Michael S Parker, Armin Buschauer, Ambikaipakan Balasubramaniam. Ligand internalization by cloned neuropeptide Y Y5 receptors excludes Y2 and Y4 receptor-selective peptides.
European journal of pharmacology.
2003 Aug; 474(1):31-42. doi:
10.1016/s0014-2999(03)02039-9. [PMID: 12909193] - Leonard J Foster, Carmen L De Hoog, Matthias Mann. Unbiased quantitative proteomics of lipid rafts reveals high specificity for signaling factors.
Proceedings of the National Academy of Sciences of the United States of America.
2003 May; 100(10):5813-8. doi:
10.1073/pnas.0631608100. [PMID: 12724530] - Shigeki Sugii, Patrick C Reid, Nobutaka Ohgami, Yukiko Shimada, Robert A Maue, Haruaki Ninomiya, Yoshiko Ohno-Iwashita, Ta-Yuan Chang. Biotinylated theta-toxin derivative as a probe to examine intracellular cholesterol-rich domains in normal and Niemann-Pick type C1 cells.
Journal of lipid research.
2003 May; 44(5):1033-41. doi:
10.1194/jlr.d200036-jlr200. [PMID: 12562855] - Volker Wachtler, Srividya Rajagopalan, Mohan K Balasubramanian. Sterol-rich plasma membrane domains in the fission yeast Schizosaccharomyces pombe.
Journal of cell science.
2003 Mar; 116(Pt 5):867-74. doi:
10.1242/jcs.00299. [PMID: 12571284] - Marc Walter, Joanna P Davies, Yiannis A Ioannou. Telomerase immortalization upregulates Rab9 expression and restores LDL cholesterol egress from Niemann-Pick C1 late endosomes.
Journal of lipid research.
2003 Feb; 44(2):243-53. doi:
10.1194/jlr.m200230-jlr200. [PMID: 12576506] - P Ramoino, P Fronte, M Fato, F Beltrame, A Diaspro. Mapping cholesteryl ester analogue uptake and intracellular flow in Paramecium by confocal fluorescence microscopy.
Journal of microscopy.
2002 Dec; 208(Pt 3):167-76. doi:
10.1046/j.1365-2818.2002.01078.x. [PMID: 12460448]
