2-[3-[1-[3-[2-(2-Methoxyethoxycarbonylamino)ethylamino]-3-oxopropyl]-2,5-dioxopyrrolidin-3-yl]sulfanylpropylamino]-4-methylsulfanylbutanoic acid (BioDeep_00000912286)
代谢物信息卡片
化学式: C21H36N4O8S2 (536.1974456)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COCCOC(=O)NCCNC(=O)CCN1C(=O)CC(C1=O)SCCCNC(CCSC)C(=O)O
InChI: InChI=1S/C21H36N4O8S2/c1-32-10-11-33-21(31)24-8-7-23-17(26)4-9-25-18(27)14-16(19(25)28)35-12-3-6-22-15(20(29)30)5-13-34-2/h15-16,22H,3-14H2,1-2H3,(H,23,26)(H,24,31)(H,29,30)
描述信息
D013501 - Surface-Active Agents > D011092 - Polyethylene Glycols
D001697 - Biomedical and Dental Materials
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Chaoying Hu, Bingxin Ji, Xiao Hu, Cuicui Yang, Wanling Sun, Xiaowei Zhao, Lin Li, Xiaoying Li, Lan Zhang. Pharmacokinetics and Pharmacodynamics of Two Formulations of Pegylated Recombinant Human Granulocyte Colony-Stimulating Factor in Healthy Chinese Subjects: An Open-Label, Randomized, Parallel-Design Bioavailability Study.
Clinical pharmacology in drug development.
2021 03; 10(3):291-298. doi:
10.1002/cpdd.819. [PMID: 32567217] - Weiwei Huang, Jian Liu, Yi Zeng, Fan Wu, Nani Li, Kan Chen, Yi Hong, LiLi Wang, Hongyu Zhen, Lin Lin. Randomized controlled clinical trial of polyethylene glycol recombinant human granulocyte colony-stimulating factor in the treatment of neutropenia after chemotherapy for breast cancer.
Cancer chemotherapy and pharmacology.
2018 10; 82(4):607-613. doi:
10.1007/s00280-018-3639-z. [PMID: 30043207] - Michael J Haller, Desmond A Schatz, Jay S Skyler, Jeffrey P Krischer, Brian N Bundy, Jessica L Miller, Mark A Atkinson, Dorothy J Becker, David Baidal, Linda A DiMeglio, Stephen E Gitelman, Robin Goland, Peter A Gottlieb, Kevan C Herold, Jennifer B Marks, Antoinette Moran, Henry Rodriguez, William Russell, Darrell M Wilson, Carla J Greenbaum. Low-Dose Anti-Thymocyte Globulin (ATG) Preserves β-Cell Function and Improves HbA1c in New-Onset Type 1 Diabetes.
Diabetes care.
2018 Sep; 41(9):1917-1925. doi:
10.2337/dc18-0494. [PMID: 30012675] - Tobias Frank, Florian Klinker, Björn H Falkenburger, Rico Laage, Fred Lühder, Bettina Göricke, Armin Schneider, Hartmud Neurath, Herbert Desel, David Liebetanz, Mathias Bähr, Jochen H Weishaupt. Pegylated granulocyte colony-stimulating factor conveys long-term neuroprotection and improves functional outcome in a model of Parkinson's disease.
Brain : a journal of neurology.
2012 Jun; 135(Pt 6):1914-25. doi:
10.1093/brain/aws054. [PMID: 22427327] - P van Der Auwera, E Platzer, Z X Xu, R Schulz, O Feugeas, R Capdeville, D J Edwards. Pharmacodynamics and pharmacokinetics of single doses of subcutaneous pegylated human G-CSF mutant (Ro 25-8315) in healthy volunteers: comparison with single and multiple daily doses of filgrastim.
American journal of hematology.
2001 Apr; 66(4):245-51. doi:
10.1002/ajh.1052. [PMID: 11279634]