Methyl 33-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-1,3,5,7,9,13,37-heptahydroxy-17-[5-hydroxy-7-[4-(methylamino)phenyl]-7-oxoheptan-2-yl]-18-methyl-11,15-dioxo-16,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate (BioDeep_00000912279)

代谢物信息卡片

Methyl 33-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-1,3,5,7,9,13,37-heptahydroxy-17-[5-hydroxy-7-[4-(methylamino)phenyl]-7-oxoheptan-2-yl]-18-methyl-11,15-dioxo-16,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate

化学式: C60H88N2O19 (1140.5980978)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1C=CC=CC=CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC(CC(CC(CC(=O)CC(CC(=O)OC1C(C)CCC(CC(=O)C3=CC=C(C=C3)NC)O)O)O)O)O)O)O)O)C(=O)OC)OC4C(C(C(C(O4)C)O)N)O
InChI: InChI=1S/C60H88N2O19/c1-36-18-16-14-12-10-8-6-7-9-11-13-15-17-19-48(79-59-56(74)54(61)55(73)38(3)78-59)33-51-53(58(75)77-5)50(71)35-60(76,81-51)34-47(69)30-45(67)28-43(65)26-42(64)27-44(66)29-46(68)32-52(72)80-57(36)37(2)20-25-41(63)31-49(70)39-21-23-40(62-4)24-22-39/h6-19,21-24,36-38,41-43,45-48,50-51,53-57,59,62-65,67-69,71,73-74,76H,20,25-35,61H2,1-5H3

描述信息

D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
D000089162 - Genitourinary Agents > D064804 - Urological Agents
D000890 - Anti-Infective Agents > D000935 - Antifungal Agents

同义名列表

1 个代谢物同义名

数据库引用编号

2 个数据库交叉引用编号

PubChem: 73161212
MeSH: Mepartricin

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

R Barbero, P Badino, R Odore, M R Galmozzi, B Cuniberti, R Zanatta, G Re. Mepartricin long-term administration regulates steroid hormone and adrenergic receptor concentrations in the prostate of aged rats. Journal of veterinary pharmacology and therapeutics. 2006 Aug; 29(4):289-97. doi: 10.1111/j.1365-2885.2006.00745.x. [PMID: 16846466]
Shuji Shakuto, Eiko Tsuchiya. Effects of mepartricin, a polyene macrolide antibiotic, on estrogen-induced hyperplastic growth of the dorsolateral prostate and seminal vesicle in immature castrated rats. Scandinavian journal of urology and nephrology. 2005; 39(5):358-65. doi: 10.1080/00365590500199178. [PMID: 16257836]
G Re, P Badino, R Odore, D Vigo, A Bonabello, S Rabino, F Capello, T Bruzzese. Effects of mepartricin on estradiol and testosterone serum levels and on prostatic estrogen, androgen and adrenergic receptor concentrations in adult rats. Pharmacological research. 2001 Aug; 44(2):141-7. doi: 10.1006/phrs.2001.0846. [PMID: 11516265]
D Barone, F Peroglio, E Toso, T Bruzzese. Binding of mepartricin to sex hormones, a key factor of its activity on benign prostatic hyperplasia. Arzneimittel-Forschung. 2001; 51(12):984-90. doi: 10.1055/s-0031-1300149. [PMID: 11799846]
Y Yoshinaka, H Kobayasi, J Kirihara, F Sato, S Shakutou, H Yamanaka. Effects of mepartricin (S-160) on spontaneous canine benign prostatic hyperplasia. European urology. 2000 Apr; 37(4):428-35. doi: 10.1159/000020164. [PMID: 10765073]
S Shakutou, K Bandoh, Y Yoshinaka, H Kobayashi, H Yamanaka. Effects of mepartricin, a polyene macrolide agent, on fecal excretion and serum concentration of estrogen and number of prostatic estrogen receptors in immature rats. The Prostate. 1999 Jan; 38(1):17-27. doi: 10.1002/(sici)1097-0045(19990101)38:1<17::aid-pros2>3.0.co;2-t. [PMID: 9973105]
L Denis, F Pagano, A Nonis, C Robertson, P Romano, P Boyle. Double-blind, placebo-controlled trial to assess the efficacy and tolerability of mepartricin in the treatment of BPH. The Prostate. 1998 Dec; 37(4):246-52. doi: 10.1002/(sici)1097-0045(19981201)37:4<246::aid-pros6>3.0.co;2-6. [PMID: 9831221]
F C Lowe, K Dreikorn, A Borkowski, J Braeckman, L Denis, P Ferrari, G Gerber, R Levin, P Perrin, T Senge. Review of recent placebo-controlled trials utilizing phytotherapeutic agents for treatment of BPH. The Prostate. 1998 Nov; 37(3):187-93. doi: 10.1002/(sici)1097-0045(19981101)37:3<187::aid-pros8>3.0.co;2-t. [PMID: 9792136]
E Martini, L Vaggi, A Rucci, L Di Clemente. [Non surgical treatment of benign prostatic hypertrophy]. Journal d'urologie. 1993; 99(6):278-82. doi: ". [PMID: 7516366]
S Del Vecchio, A Ulissi, M Delle Monache, A Tavanti, M Rapocci, P Ruozi, M De Bernardi, G L Ricci. Faecal elimination of steroids in rats after oral administration of mepartricin. The Journal of international medical research. 1990 Nov; 18(6):468-72. doi: 10.1177/030006059001800604. [PMID: 2292328]
A Piccinno, E Cirillo Marucco, G M Ludovico, A Pagliarulo. Study of mepartricin possible interactions with antilipemic drugs. Controlled clinical trials in patients with benign prostatic hyperplasia. Panminerva medica. 1990 Jul; 32(3):122-5. doi: ". [PMID: 1706493]
A Tavanti, M Delle Monache, A Ulissi, S Del Vecchio, M A Rapocci, P Ruozi, M De Bernardi, G L Ricci. Changes in the plasma pattern of sex steroids in patients with liver cirrhosis treated with mepartricin. The Journal of international medical research. 1989 May; 17(3):212-7. doi: 10.1177/030006058901700303. [PMID: 2504629]
F Sciarra, P Bianchi, V Toscano. [Effect of treatment with mepartricin on the plasma androgen and gonadotropin concentrations in subjects with benign prostatic hypertrophy]. Minerva urologica e nefrologica = The Italian journal of urology and nephrology. 1988 Apr; 40(2 Suppl):10-2. doi: NULL. [PMID: 2460936]
M A Petrou, T R Rogers. A comparison of the activity of mepartricin and amphotericin B against yeasts. The Journal of antimicrobial chemotherapy. 1985 Aug; 16(2):169-77. doi: 10.1093/jac/16.2.169. [PMID: 3905747]
A Barbaro, G Casella. [Action of a polyene macrolide on hyperdyslipidemic disorders]. Archivio per le scienze mediche. 1980 Apr; 137(2):211-6. doi: ". [PMID: 7224842]
M Eandi, P Ruozi, F Granata, S Ricci-Gamalero. [Clinico-experimental correlation of the hypolipemic effects of mepartricin]. Archivio per le scienze mediche. 1979 Oct; 136(4):603-6. doi: NULL. [PMID: 550761]