Fluorodihydrouracil (BioDeep_00000912172)
代谢物信息卡片
化学式: C4H5FN2O2 (132.0335042)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CN(C(=O)NC1=O)F
InChI: InChI=1S/C4H5FN2O2/c5-7-2-1-3(8)6-4(7)9/h1-2H2,(H,6,8,9)
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Bunzo Nakata, Ryosuke Amano, Shigetomi Nakao, Tatsuro Tamura, Osamu Shinto, Toshiki Hirakawa, Yoshihiro Okita, Nobuya Yamada, Kosei Hirakawa. Plasma pharmacokinetics after combined therapy of gemcitabine and oral S-1 for unresectable pancreatic cancer.
Journal of experimental & clinical cancer research : CR.
2010 Feb; 29(?):15. doi:
10.1186/1756-9966-29-15
. [PMID: 20181235] - Woo Young Kim, Bunzo Nakata, Kosei Hirakawa. Alternative pharmacokinetics of S-1 components, 5-fluorouracil, dihydrofluorouracil and alpha-fluoro-beta-alanine after oral administration of S-1 following total gastrectomy.
Cancer science.
2007 Oct; 98(10):1604-8. doi:
10.1111/j.1349-7006.2007.00573.x
. [PMID: 17683513] - Jan Gerard Maring, Leonie Schouten, Ben Greijdanus, Elisabeth G E de Vries, Donald R A Uges. A simple and sensitive fully validated HPLC-UV method for the determination of 5-fluorouracil and its metabolite 5,6-dihydrofluorouracil in plasma.
Therapeutic drug monitoring.
2005 Feb; 27(1):25-30. doi:
10.1097/00007691-200502000-00006
. [PMID: 15665742] - Jan Gerard Maring, Henk Piersma, Albert van Dalen, Harry J M Groen, Donald R A Uges, Elisabeth G E De Vries. Extensive hepatic replacement due to liver metastases has no effect on 5-fluorouracil pharmacokinetics.
Cancer chemotherapy and pharmacology.
2003 Feb; 51(2):167-73. doi:
10.1007/s00280-002-0535-2
. [PMID: 12647019] - Madhu B Garg, Jade C Sevester, Jennette A Sakoff, Stephen P Ackland. Simple liquid chromatographic method for the determination of uracil and dihydrouracil plasma levels: a potential pretreatment predictor of 5-fluorouracil toxicity.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2002 Jul; 774(2):223-30. doi:
10.1016/s1570-0232(02)00239-8
. [PMID: 12076692] - Jens Rengelshausen, William E Hull, Vedat Schwenger, Christoph Göggelmann, Ingeborg Walter-Sack, Jürgen Bommer. Pharmacokinetics of 5-fluorouracil and its catabolites determined by 19F nuclear magnetic resonance spectroscopy for a patient on chronic hemodialysis.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2002 Feb; 39(2):E10. doi:
10.1053/ajkd.2002.30584
. [PMID: 11840401]