H-DL-Met-DL-Ala-DL-xiThr-DL-Tyr-DL-Arg-DL-Ser-OH (BioDeep_00000911403)
代谢物信息卡片
化学式: C30H49N9O10S (727.3322934)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCCN=C(N)N)C(=O)NC(CO)C(=O)O)NC(=O)C(C)NC(=O)C(CCSC)N)O
InChI: InChI=1S/C30H49N9O10S/c1-15(35-25(44)19(31)10-12-50-3)24(43)39-23(16(2)41)28(47)37-21(13-17-6-8-18(42)9-7-17)27(46)36-20(5-4-11-34-30(32)33)26(45)38-22(14-40)29(48)49/h6-9,15-16,19-23,40-42H,4-5,10-14,31H2,1-3H3,(H,35,44)(H,36,46)(H,37,47)(H,38,45)(H,39,43)(H,48,49)(H4,32,33,34)
描述信息
D000970 - Antineoplastic Agents
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Velu Nair, Ajay Sharma, Satyaranjan Das, Vishal Sondhi, Sanjeevan Sharma. Immunosuppressive therapy in adults with aplastic anaemia: single-institution experience from India.
Postgraduate medical journal.
2013 Sep; 89(1055):508-15. doi:
10.1136/postgradmedj-2011-130605
. [PMID: 23686628] - Keikou Okasaki, Mamoru Funato, Masatoshi Kashima, Kazuhiro Nakama, Takatoshi Inoue, Masanori Hiura, Yuzuru Kato, Ryoichi Nagata. Twenty-six-week repeat-dose toxicity study of a recombinant human granulocyte colony-stimulating factor derivative (nartograstim) in cynomolgus monkeys.
Toxicological sciences : an official journal of the Society of Toxicology.
2002 Feb; 65(2):246-55. doi:
10.1093/toxsci/65.2.246
. [PMID: 11812929] - J F Eliason, A Greway, N Tare, T Inoue, S Bowen, M Dar, M Yamasaki, M Okabe, I Horii. Extended activity in cynomolgus monkeys of a granulocyte colony-stimulating factor mutein conjugated with high molecular weight polyethylene glycol.
Stem cells (Dayton, Ohio).
2000; 18(1):40-5. doi:
10.1634/stemcells.18-1-40
. [PMID: 10661570] - H Tanaka, Y Tanaka, K Shinagawa, Y Yamagishi, K Ohtaki, K Asano. Three types of recombinant human granulocyte colony-stimulating factor have equivalent biological activities in monkeys.
Cytokine.
1997 May; 9(5):360-9. doi:
10.1006/cyto.1996.0177
. [PMID: 9195136] - T Kuwabara, Y Ishikawa, H Kobayashi, S Kobayashi, Y Sugiyama. Renal clearance of a recombinant granulocyte colony-stimulating factor, nartograstim, in rats.
Pharmaceutical research.
1995 Oct; 12(10):1466-9. doi:
10.1023/a:1016227202781
. [PMID: 8584482] - T Kuwabara, T Uchimura, K Takai, H Kobayashi, S Kobayashi, Y Sugiyama. Saturable uptake of a recombinant human granulocyte colony-stimulating factor derivative, nartograstim, by the bone marrow and spleen of rats in vivo.
The Journal of pharmacology and experimental therapeutics.
1995 Jun; 273(3):1114-22. doi:
NULL
. [PMID: 7540687] - T Kuwabara, Y Kato, S Kobayashi, H Suzuki, Y Sugiyama. Nonlinear pharmacokinetics of a recombinant human granulocyte colony-stimulating factor derivative (nartograstim): species differences among rats, monkeys and humans.
The Journal of pharmacology and experimental therapeutics.
1994 Dec; 271(3):1535-43. doi:
NULL
. [PMID: 7527856] - M Yamasaki, M Asano, M Okabe, M Morimoto, Y Yokoo. Modification of recombinant human granulocyte colony-stimulating factor (rhG-CSF) and its derivative ND 28 with polyethylene glycol.
Journal of biochemistry.
1994 May; 115(5):814-9. doi:
10.1093/oxfordjournals.jbchem.a124421
. [PMID: 7525544] - T Kuwabara, S Okumura, S Kobayashi, T Hirata. Highly sensitive enzyme-linked immunosorbent assay for marograstim (KW-2228), a mutant of human granulocyte colony-stimulating factor.
Journal of pharmacobio-dynamics.
1992 Mar; 15(3):121-9. doi:
10.1248/bpb1978.15.121
. [PMID: 1378090] - T Yoshino, K Sato. [Combination effect of KW-2228 and aminoglycoside antibiotics on systemic infection in cyclophosphamide-treated tumor-bearing mice].
The Japanese journal of antibiotics.
1992 Jan; 45(1):98-105. doi:
. [PMID: 1379653]
- K Sato, H Yoneyama, T Yoshino. [Combination effects between KW-2228 and antibiotics against systemic infections in normal and neutropenic mice].
The Japanese journal of antibiotics.
1992 Jan; 45(1):91-7. doi:
. [PMID: 1379652]
- T Yoshino, K Sato. [Combination effect of KW-2228 and cephem antibiotics in a systemic infection model in neutropenic mice].
The Japanese journal of antibiotics.
1992 Jan; 45(1):106-11. doi:
. [PMID: 1379649]
- H Yoshitake, K Sato. [Effects of KW-2228 on the function of polymorphonuclear neutrophils in rats for the phagocytosis and killing activity and the production of active oxygen].
The Japanese journal of antibiotics.
1992 Jan; 45(1):112-20. doi:
NULL
. [PMID: 1379650] - T Yoshino, K Sato. [Protective effect of KW-2228 in a systemic infection model of CPA-treated tumor-bearing mice].
The Japanese journal of antibiotics.
1992 Jan; 45(1):87-90. doi:
NULL
. [PMID: 1379651]