Hapten (BioDeep_00000911377)
代谢物信息卡片
Hapten
化学式: C26H26ClN5O3S (523.1444796000001)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1C2=NN=C(N2C3=C(C4=C(S3)CN(CC4)C(=O)C5CC5)C(=N1)C6=C(C=C(C=C6)CCC(=O)O)Cl)C
InChI: InChI=1S/C26H26ClN5O3S/c1-13-24-30-29-14(2)32(24)26-22(18-9-10-31(12-20(18)36-26)25(35)16-5-6-16)23(28-13)17-7-3-15(11-19(17)27)4-8-21(33)34/h3,7,11,13,16H,4-6,8-10,12H2,1-2H3,(H,33,34)
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Rubing Zou, Yuanhao Guo, Yan Wang, Xinying Lu, Zhongjie Ma, Linfei Shou, Yihua Liu, Guonian Zhu, Yirong Guo. Insights into the Binding Profile of Anti-chlorpyrifos Recombinant Antibodies: From Computational Simulation to Immunoassay Validation.
Analytical chemistry.
2023 08; 95(30):11287-11295. doi:
10.1021/acs.analchem.3c01355. [PMID: 37459591] - Kangliang Pan, Zhiwei Liu, Zhaodong Li, Mindan Chen, Qiqi Quan, Xiaoqin Yu, Yi Lei, Qiuhua Mo, Bingzhi Wang, Tian Guan, Hongtao Lei. Identifying fungicide difenoconazole as illegal growth regulator in vegetable: Computer-aided hapten similarity to enhance immunoassay sensitivity.
Analytica chimica acta.
2023 Jun; 1258(?):341182. doi:
10.1016/j.aca.2023.341182. [PMID: 37087291] - Qiqi Quan, Zhiwei Liu, Zhaodong Li, Kangliang Pan, Anastasios Koidis, Yi Lei, Xiaoqin Yu, Qiuhua Mo, Xinan Huang, Hongtao Lei. Authenticating Emergent Adulterant 6-Benzylaminopurine in Bean Sprouts: Virtual Hapten Similarity Enhanced Immunoassay.
Journal of agricultural and food chemistry.
2023 May; 71(21):8203-8210. doi:
10.1021/acs.jafc.3c01696. [PMID: 37199564] - Wanwan Wang, Ge Sun, Xiaoke Nan, Yazhuo Huang, Zhehao Li, Tian He, Yukun Luo, Shizhong Chen. On-line screening and verification of haptens in Xiangdan injection combining chemical analysis with activity detection.
Journal of pharmaceutical and biomedical analysis.
2023 Apr; 231(?):115413. doi:
10.1016/j.jpba.2023.115413. [PMID: 37119721] - Weixuan Wang, Gan Gu, Ruya Yin, Jiajin Fu, Mingpeng Jing, Zhen Shen, Daowan Lai, Baomin Wang, Ligang Zhou. A Nanobody-Based Immunoassay for Detection of Ustilaginoidins in Rice Samples.
Toxins.
2022 Sep; 14(10):. doi:
10.3390/toxins14100659. [PMID: 36287930] - Lianrun Huang, He Chen, Panpan Cui, Yuan Ding, Minghua Wang, Xiude Hua. Development of immunoassay based on rational hapten design for sensitive detection of pendimethalin in environment.
The Science of the total environment.
2022 Jul; 830(?):154690. doi:
10.1016/j.scitotenv.2022.154690. [PMID: 35318054] - Yudan Wang, Jia' An Qin, Jing Zhang, Ziyue Jin, Jiaoyang Luo, Meihua Yang. Rapid screening of imidacloprid residue in grains and medicinal herbs: A newly designed hapten and monoclonal antibody.
Journal of pharmaceutical and biomedical analysis.
2022 Jul; 219(?):114931. doi:
10.1016/j.jpba.2022.114931. [PMID: 35839580] - Harrison M McCann, Benjamin P M Lake, Kyle S Hoffman, Maria E Davola, Karen L Mossman, Anthony F Rullo. Covalent Immune Proximity-Induction Strategy Using SuFEx-Engineered Bifunctional Viral Peptides.
ACS chemical biology.
2022 05; 17(5):1269-1281. doi:
10.1021/acschembio.2c00233. [PMID: 35522208] - Jiayin Han, Chen Pan, Xuan Tang, Qi Li, Yan Zhu, Yushi Zhang, Aihua Liang. Hypersensitivity reactions to small molecule drugs.
Frontiers in immunology.
2022; 13(?):1016730. doi:
10.3389/fimmu.2022.1016730. [PMID: 36439170] - Jongmin Ahn, Cristina Avonto, Amar G Chittiboyina, Ikhlas A Khan. Solvents effect on dansyl cysteamine depletion and reactivity classification of skin sensitizers: Tackling the challenges using binary solvent systems.
Journal of pharmacological and toxicological methods.
2021 Nov; 112(?):107116. doi:
10.1016/j.vascn.2021.107116. [PMID: 34403747] - Guohua Wang, Dawei Zou, Yixuan Wang, Nancy M Gonzalez, Stephanie G Yi, Xian C Li, Wenhao Chen, A Osama Gaber. IRF4 ablation in B cells abrogates allogeneic B cell responses and prevents chronic transplant rejection.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
2021 10; 40(10):1122-1132. doi:
10.1016/j.healun.2021.06.008. [PMID: 34253454] - Yuchen Bai, Yahui Wang, Qiang Li, Leina Dou, Minggang Liu, Shibei Shao, Jianyu Zhu, Jianzhong Shen, Zhanhui Wang, Kai Wen, Wenbo Yu. Binding affinity-guided design of a highly sensitive noncompetitive immunoassay for small molecule detection.
Food chemistry.
2021 Jul; 351(?):129270. doi:
10.1016/j.foodchem.2021.129270. [PMID: 33640770] - Eden Kapcan, Benjamin Lake, Zi Yang, Ali Zhang, Matthew S Miller, Anthony F Rullo. Covalent Stabilization of Antibody Recruitment Enhances Immune Recognition of Cancer Targets.
Biochemistry.
2021 05; 60(19):1447-1458. doi:
10.1021/acs.biochem.1c00127. [PMID: 33930269] - Megan M Dacek, Darren R Veach, Sarah M Cheal, Lukas M Carter, Michael R McDevitt, Blesida Punzalan, Daniela Burnes Vargas, Thomas Z Kubik, Sebastien Monette, Brian H Santich, Guangbin Yang, Ouathek Ouerfelli, Adam L Kesner, Nai-Kong V Cheung, David A Scheinberg, Steven M Larson, Simone Krebs. Engineered Cells as a Test Platform for Radiohaptens in Pretargeted Imaging and Radioimmunotherapy Applications.
Bioconjugate chemistry.
2021 04; 32(4):649-654. doi:
10.1021/acs.bioconjchem.0c00595. [PMID: 33819023] - Cristina Avonto, Amar G Chittiboyina, Shabana I Khan, Olivia R Dale, Jon F Parcher, Mei Wang, Ikhlas A Khan. Are atranols the only skin sensitizers in oakmoss? A systematic investigation using non-animal methods.
Toxicology in vitro : an international journal published in association with BIBRA.
2021 Feb; 70(?):105053. doi:
10.1016/j.tiv.2020.105053. [PMID: 33212168] - Rebecca Young, Dylan E Jones, Lautaro Diacovich, Andrzej Witkowski, Robert O Ryan. trans-3-Methylglutaconyl CoA isomerization-dependent protein acylation.
Biochemical and biophysical research communications.
2021 01; 534(?):261-265. doi:
10.1016/j.bbrc.2020.11.100. [PMID: 33280817] - Edurne Peña-Mendizabal, Sergi Morais, Ángel Maquieira. Boosting the sensitivity of in vitroβ-lactam allergy diagnostic tests.
Chemical communications (Cambridge, England).
2020 Oct; 56(80):11973-11976. doi:
10.1039/d0cc04903d. [PMID: 33033809] - Datis Kharrazian, Martha Herbert, Aristo Vojdani. Cross-Reactivity between Chemical Antibodies Formed to Serum Proteins and Thyroid Axis Target Sites.
International journal of molecular sciences.
2020 Oct; 21(19):. doi:
10.3390/ijms21197324. [PMID: 33023043] - Xianlu Lei, Xinxin Xu, Liqiang Liu, Hua Kuang, Liguang Xu, Changlong Hao, Chuanlai Xu. Rapid quantitative determination of fentanyl in human urine and serum using a gold-based immunochromatographic strip sensor.
Journal of materials chemistry. B.
2020 09; 8(37):8573-8584. doi:
10.1039/d0tb01509a. [PMID: 32814936] - Rodell C Barrientos, Eric W Bow, Connor Whalen, Oscar B Torres, Agnieszka Sulima, Zoltan Beck, Arthur E Jacobson, Kenner C Rice, Gary R Matyas. Novel Vaccine That Blunts Fentanyl Effects and Sequesters Ultrapotent Fentanyl Analogues.
Molecular pharmaceutics.
2020 09; 17(9):3447-3460. doi:
10.1021/acs.molpharmaceut.0c00497. [PMID: 32787282] - Ibrahim A Darwish, Abdulrahman A Almehizia, Awwad A Radwan, Rashed N Herqash. Preparation and Characterization of Two Immunogens and Production of Polyclonal Antibody with High Affinity and Specificity for Darunavir.
Molecules (Basel, Switzerland).
2020 Sep; 25(18):. doi:
10.3390/molecules25184075. [PMID: 32906585] - István Köteles, Károly Mazák, Gergő Tóth, Boglárka Tűz, Sándor Hosztafi. Synthesis of Potential Haptens with Morphine Skeleton and Determination of Protonation Constants.
Molecules (Basel, Switzerland).
2020 Sep; 25(17):. doi:
10.3390/molecules25174009. [PMID: 32887468] - Shenzhi Zhou, Na Zhang, Zixia Hu, Dongju Lin, Weiwei Li, Ying Peng, Jiang Zheng. Immunochemical Detection of Protein Modification Derived from Metabolic Activation of 8-Epidiosbulbin E Acetate.
Chemical research in toxicology.
2020 07; 33(7):1752-1760. doi:
10.1021/acs.chemrestox.0c00016. [PMID: 32347100] - Zi-Jian Chen, Xi-Xia Liu, Zhi-Li Xiao, Hui-Jun Fu, Yu-Ping Huang, Shu-Yi Huang, Yu-Dong Shen, Fan He, Xing-Xing Yang, Bruce Hammock, Zhen-Lin Xu. Production of a specific monoclonal antibody for 1-naphthol based on novel hapten strategy and development of an easy-to-use ELISA in urine samples.
Ecotoxicology and environmental safety.
2020 Jun; 196(?):110533. doi:
10.1016/j.ecoenv.2020.110533. [PMID: 32247241] - Aline Murawski, Maria I H Schmied-Tobies, Enrico Rucic, Thomas Schettgen, Jens Bertram, André Conrad, Marike Kolossa-Gehring. The methylisothiazolinone and methylchloroisothiazolinone metabolite N-methylmalonamic acid (NMMA) in urine of children and adolescents in Germany - Human biomonitoring results of the German Environmental Survey 2014-2017 (GerES V).
International journal of hygiene and environmental health.
2020 06; 227(?):113511. doi:
10.1016/j.ijheh.2020.113511. [PMID: 32174480] - Sarah M Cheal, Mitesh Patel, Guangbin Yang, Darren Veach, Hong Xu, Hong-Fen Guo, Pat B Zanzonico, Donald B Axworthy, Nai-Kong V Cheung, Ouathek Ouerfelli, Steven M Larson. An N-Acetylgalactosamino Dendron-Clearing Agent for High-Therapeutic-Index DOTA-Hapten Pretargeted Radioimmunotherapy.
Bioconjugate chemistry.
2020 03; 31(3):501-506. doi:
10.1021/acs.bioconjchem.9b00736. [PMID: 31891487] - Hoang-Thanh Le, Nya L Fraleigh, Jordan D Lewicky, Justin Boudreau, Paul Dolinar, Nitin Bhardwaj, Francisco Diaz-Mitoma, Sabine Montaut, Sarah Fallahi, Alexandrine L Martel. Enhancing the Immune Response of a Nicotine Vaccine with Synthetic Small 'Non-Natural' Peptides.
Molecules (Basel, Switzerland).
2020 Mar; 25(6):. doi:
10.3390/molecules25061290. [PMID: 32178357] - Xingdong Yang, Yinbiao Wang, Chunmei Song, Xiaofei Hu, Fangyu Wang, Xianyin Zeng. Hapten Synthesis and the Development of an Ultrasensitive Indirect Competitive ELISA for the Determination of Diethylstilbestrol in Food Samples.
Scientific reports.
2020 02; 10(1):3270. doi:
10.1038/s41598-020-59112-1. [PMID: 32094434] - Erika Parkinson, Maja Aleksic, Rachael Arthur, Sergio Regufe Da Mota, Richard Cubberley, Paul J Skipp. Proteomic analysis of haptenation by skin sensitisers: Diphencyprone and ethyl acrylate.
Toxicology in vitro : an international journal published in association with BIBRA.
2020 Feb; 62(?):104697. doi:
10.1016/j.tiv.2019.104697. [PMID: 31669365] - Song Hu, Zhen Huang, Chun Wang, Juan Peng, Wei-Hua Lai. Using hapten cross-reactivity to screen heterologous competitive antigens for improving the sensitivity of ELISA.
Food chemistry.
2020 Jan; 303(?):125379. doi:
10.1016/j.foodchem.2019.125379. [PMID: 31446361] - Qiuli Ouyang, Xiangxiang Liu, Rongxia Tan, Lan Guo, Fan Liu, Yiqun Wan. Polyclonal antibody-based indirect competitive enzyme-linked immunosorbent assay for screening of paclobutrazol in fruits.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.
2020; 55(3):250-256. doi:
10.1080/03601234.2019.1685319. [PMID: 31694450] - Castillo-Maldonado Irais, Sevilla-González María-de-la-Luz, Delgadillo-Guzmán Dealmy, Ramírez-Moreno Agustina, Cabral-Hipólito Nidia, Rivera-Guillén Mario-Alberto, Serrano-Gallardo Luis-Benjamín, Vega-Menchaca María-Del-Carmen, Pedroza-Escobar David. Plant Phenolics as Pathogen-Carrier Immunogenicity Modulator Haptens.
Current pharmaceutical biotechnology.
2020; 21(10):897-905. doi:
10.2174/1389201021666200121130313. [PMID: 31965941] - Ruriko Suzuki, Yoshikazu Inoh, Satoru Yokawa, Ryo Suzuki, Tadahide Furuno, Naohide Hirashima. Monomer hapten and hapten-specific IgG inhibit mast cell activation evoked by multivalent hapten with different mechanisms.
European journal of immunology.
2019 12; 49(12):2172-2183. doi:
10.1002/eji.201847973. [PMID: 31339552] - Arun Tailor, James C Waddington, Jane Hamlett, James Maggs, Laila Kafu, John Farrell, Gordon J Dear, Paul Whitaker, Dean J Naisbitt, Kevin Park, Xiaoli Meng. Definition of Haptens Derived from Sulfamethoxazole: In Vitro and in Vivo.
Chemical research in toxicology.
2019 10; 32(10):2095-2106. doi:
10.1021/acs.chemrestox.9b00282. [PMID: 31468968] - Andrew N Glushkov, Elena G Polenok, Stella A Mun, Lyudmila A Gordeeva. Immunization against environmental chemical carcinogens: Pro and contra.
Medical hypotheses.
2019 Oct; 131(?):109303. doi:
10.1016/j.mehy.2019.109303. [PMID: 31443747] - Yongliang Cui, Jing Zhao, Jie Zhou, Guiyu Tan, Qiyang Zhao, Yaohai Zhang, Baomin Wang, Bining Jiao. Development of a sensitive monoclonal antibody-based indirect competitive enzyme-linked immunosorbent assay for analysing nobiletin in citrus and herb samples.
Food chemistry.
2019 Sep; 293(?):144-150. doi:
10.1016/j.foodchem.2019.04.101. [PMID: 31151594] - Xiaoxia Zhu, Xiaye Miao, Xinyue Qin, Xiaohong Zhu. Design of immunogens: The effect of bifunctional chelator on immunological response to chelated copper.
Journal of pharmaceutical and biomedical analysis.
2019 Sep; 174(?):263-269. doi:
10.1016/j.jpba.2019.06.001. [PMID: 31181489] - Masaharu Fujita, Yusuke Yamamoto, Sayaka Wanibuchi, Yasuhiro Katsuoka, Toshihiko Kasahara. A newly developed means of HPLC-fluorescence analysis for predicting the skin sensitization potential of multi-constituent substances using ADRA.
Toxicology in vitro : an international journal published in association with BIBRA.
2019 Sep; 59(?):161-178. doi:
10.1016/j.tiv.2019.04.014. [PMID: 31002975] - Yanyan Niu, Hong Wang, Xin Tong, Xiang Li, Ning Guo, Xiaotian Zhang, Yukun Luo, Yaning Gao, Tian He, Zongtao Lin, Shizhong Chen. Development of an on-line analytical platform to screen haptens in shuxuening injection based on high-performance liquid chromatography coupled with ion-trap multistage mass spectrometry and human serum albumin fluorescence detection.
Journal of chromatography. A.
2019 Aug; 1598(?):232-241. doi:
10.1016/j.chroma.2019.04.011. [PMID: 30981514] - Liting Yan, Xiang Nan, Cunzheng Zhang, Haifang Wang, Xiaoyan Huang, Jun Hu, Yingqian Liu. Development of an enzyme‑linked immunosorbent assay for camptothecin.
Molecular medicine reports.
2019 Aug; 20(2):959-966. doi:
10.3892/mmr.2019.10342. [PMID: 31173229] - Fangfang Zhao, Jingkun Liu, Jinhui Luo. Development of a High-Quality ELISA Method for Dinotefuran Based on a Novel and Newly-Designed Antigen.
Molecules (Basel, Switzerland).
2019 Jul; 24(13):. doi:
10.3390/molecules24132426. [PMID: 31269647] - Peter E Deak, Baksun Kim, Byunghee Koh, Amina Abdul Qayum, Tanyel Kiziltepe, Mark H Kaplan, Basar Bilgicer. Covalent Heterobivalent Inhibitor Design for Inhibition of IgE-Dependent Penicillin Allergy in a Murine Model.
Journal of immunology (Baltimore, Md. : 1950).
2019 07; 203(1):21-30. doi:
10.4049/jimmunol.1900225. [PMID: 31101666] - Bianca Marigliani, Josemar Vinícius Maiworm Abreu Silva, Luciene Bottentuit López Balottin, Karina Ribeiro Silva, Leandra Santos Baptista, Claudia Barbosa Ladeira de Campos, Elisabeth de Fatima Pires Augusto. Adaptation of a skin sensitization assay to a chemically defined culture.
Toxicology in vitro : an international journal published in association with BIBRA.
2019 Jun; 57(?):145-153. doi:
10.1016/j.tiv.2018.12.004. [PMID: 30543842] - Jingqian Huo, Bogdan Barnych, Zhenfeng Li, Debin Wan, Dongyang Li, Natalia Vasylieva, Stevan Z Knezevic, O Adewale Osipitan, Jon E Scott, Jinlin Zhang, Bruce D Hammock. Hapten Synthesis, Antibody Development, and a Highly Sensitive Indirect Competitive Chemiluminescent Enzyme Immunoassay for Detection of Dicamba.
Journal of agricultural and food chemistry.
2019 May; 67(20):5711-5719. doi:
10.1021/acs.jafc.8b07134. [PMID: 31042038] - Rami Bechara, Bernard Maillere, Delphine Joseph, Richard J Weaver, Marc Pallardy. Identification and characterization of a naïve CD8+ T cell repertoire for benzylpenicillin.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
2019 05; 49(5):636-643. doi:
10.1111/cea.13338. [PMID: 30657219] - Eriko Nakano, Daisuke Kamei, Remi Murase, Iori Taki, Koji Karasawa, Kiyoshi Fukuhara, Shinichi Iwai. Anti-inflammatory effects of new catechin derivatives in a hapten-induced mouse contact dermatitis model.
European journal of pharmacology.
2019 Feb; 845(?):40-47. doi:
10.1016/j.ejphar.2018.12.036. [PMID: 30582907] - Toshihisa Nagao, Yoshinori Yamanishi, Kensuke Miyake, Mio Teranishi, Saori Takahashi, Soichiro Yoshikawa, Yohei Kawano, Hajime Karasuyama. Aggregation makes a protein allergenic at the challenge phase of basophil-mediated allergy in mice.
International immunology.
2019 02; 31(1):41-49. doi:
10.1093/intimm/dxy062. [PMID: 30239735] - Weiguo Li, Ranran Xu, Xiaoguang Yan, Dongmei Liang, Lei Zhang, Xiaoyu Qin, Qinggele Caiyin, Guangrong Zhao, Wenhai Xiao, Zhaonong Hu, Jianjun Qiao. De novo leaf and root transcriptome analysis to explore biosynthetic pathway of Celangulin V in Celastrus angulatus maxim.
BMC genomics.
2019 Jan; 20(1):7. doi:
10.1186/s12864-018-5397-z. [PMID: 30611193] - Mona M Al-Shehri, Adel S El-Azab, Manal A El-Gendy, Mohammed A Hamidaddin, Ibrahim A Darwish. Synthesis of hapten, generation of specific polyclonal antibody and development of ELISA with high sensitivity for therapeutic monitoring of crizotinib.
PloS one.
2019; 14(2):e0212048. doi:
10.1371/journal.pone.0212048. [PMID: 30742664] - Taku Nishijo, Masaaki Miyazawa, Kazutoshi Saito, Yuki Otsubo, Hideyuki Mizumachi, Hitoshi Sakaguchi. Sensitivity of KeratinoSensTM and h-CLAT for detecting minute amounts of sensitizers to evaluate botanical extract.
The Journal of toxicological sciences.
2019; 44(1):13-21. doi:
10.2131/jts.44.13. [PMID: 30626776] - Anna Šuláková, Lucie Fojtíková, Barbora Holubová, Kateřina Bártová, Oldřich Lapčík, Martin Kuchař. Two immunoassays for the detection of 2C-B and related hallucinogenic phenethylamines.
Journal of pharmacological and toxicological methods.
2019 Jan; 95(?):36-46. doi:
10.1016/j.vascn.2018.11.001. [PMID: 30481558] - Liting Wu, Shengli Fu, Xiaoxue Yin, Wenna Leng, Zheng Guo, Anli Wang, Jianmin Ye. Affinity maturation occurs in channel catfish (Ictalurus punctaus) following immunization with a T-cell dependent antigen.
Fish & shellfish immunology.
2019 Jan; 84(?):781-786. doi:
10.1016/j.fsi.2018.10.057. [PMID: 30393175] - T V Davydova, M A Gruden, V S Kudrin, V B Narkevich, L A Vetrile, I A Zakharova, R D E Sewell. Effect of Antibodies to Glutamate on Age-Related Memory Changes in C57Bl/6 Mice.
Bulletin of experimental biology and medicine.
2019 Jan; 166(3):326-329. doi:
10.1007/s10517-019-04343-0. [PMID: 30627908] - Bodong Li, Haibo Xie, Xian Wang, Xiaodong Yang, Ling Yang, Jiaxiang Zhang, Feng Wang, Tong Shen, Qixing Zhu. Oxidative stress mediates renal endothelial cell damage in trichloroethylene-sensitized mice.
The Journal of toxicological sciences.
2019; 44(5):317-326. doi:
10.2131/jts.44.317. [PMID: 31068537] - Rajiv W Jain, Kate A Parham, Yodit Tesfagiorgis, Heather C Craig, Emiliano Romanchik, Steven M Kerfoot. Autoreactive, Low-Affinity T Cells Preferentially Drive Differentiation of Short-Lived Memory B Cells at the Expense of Germinal Center Maintenance.
Cell reports.
2018 12; 25(12):3342-3355.e5. doi:
10.1016/j.celrep.2018.11.070. [PMID: 30566861] - Mamta Sharma, Prajna Hegde, Kavita Hiremath, Vishwanath Reddy H, A S Kamalanathan, Bale M Swamy, Shashikala R Inamdar. Purification, characterization and fine sugar specificity of a N-Acetylgalactosamine specific lectin from Adenia hondala.
Glycoconjugate journal.
2018 12; 35(6):511-523. doi:
10.1007/s10719-018-9843-6. [PMID: 30306293] - Liping Zhou, Shunyan Fang, Yanping Liu, Rong Yang, Dan Song, Feng Long, Anna Zhu. Universal and reusable hapten/antibody-mediated portable optofluidic immunosensing platform for rapid on-site detection of pathogens.
Chemosphere.
2018 Nov; 210(?):10-18. doi:
10.1016/j.chemosphere.2018.06.159. [PMID: 29980068] - Olivier Sanvido, Kaspar Schmid, Rex E FitzGerald, Nicolas Roth, Martin F Wilks, Peter Bormann, Nancy B Hopf. A quantitative risk assessment for skin sensitizing plant protection products: Linking derived No-Effect levels (DNELs) with agricultural exposure models.
Regulatory toxicology and pharmacology : RTP.
2018 Oct; 98(?):171-183. doi:
10.1016/j.yrtph.2018.07.022. [PMID: 30063949] - Brett Schrand, Emily Clark, Agata Levay, Ailem Rabasa Capote, Olivier Martinez, Randall Brenneman, Iris Castro, Eli Gilboa. Hapten-mediated recruitment of polyclonal antibodies to tumors engenders antitumor immunity.
Nature communications.
2018 08; 9(1):3348. doi:
10.1038/s41467-018-05566-x. [PMID: 30135425] - M E Azoury, L Filì, R Bechara, N Scornet, L de Chaisemartin, R J Weaver, N Claude, B Maillere, P Parronchi, D Joseph, M Pallardy. Identification of T-cell epitopes from benzylpenicillin conjugated to human serum albumin and implication in penicillin allergy.
Allergy.
2018 Aug; 73(8):1662-1672. doi:
10.1111/all.13418. [PMID: 29355985] - Xiahong Xu, Yuna Guo, Liu Wang, Kaiyu He, Yirong Guo, Xinquan Wang, Sundaram Gunasekaran. Hapten-Grafted Programmed Probe as a Corecognition Element for a Competitive Immunosensor to Detect Acetamiprid Residue in Agricultural Products.
Journal of agricultural and food chemistry.
2018 Jul; 66(29):7815-7821. doi:
10.1021/acs.jafc.8b02487. [PMID: 29944365] - Congmin Liu, Xiaowen Dou, Lei Zhang, Weijun Kong, Liu Wu, Yaping Duan, Meihua Yang. Development of a broad-specificity antibody-based immunoassay for triazines in ginger and the quantitative structure-activity relationship study of cross-reactive molecules by molecular modeling.
Analytica chimica acta.
2018 Jul; 1012(?):90-99. doi:
10.1016/j.aca.2018.01.042. [PMID: 29475478] - Oscar B Torres, Alexander J Duval, Agnieszka Sulima, Joshua F G Antoline, Arthur E Jacobson, Kenner C Rice, Carl R Alving, Gary R Matyas. A rapid solution-based method for determining the affinity of heroin hapten-induced antibodies to heroin, its metabolites, and other opioids.
Analytical and bioanalytical chemistry.
2018 Jun; 410(16):3885-3903. doi:
10.1007/s00216-018-1060-4. [PMID: 29675707] - Ayaka Kitamura, Ryohei Takata, Shin Aizawa, Hajime Watanabe, Tadashi Wada. A murine model of atopic dermatitis can be generated by painting the dorsal skin with hapten twice 14 days apart.
Scientific reports.
2018 04; 8(1):5988. doi:
10.1038/s41598-018-24363-6. [PMID: 29662233] - Zoltan Beck, Oscar B Torres, Gary R Matyas, David E Lanar, Carl R Alving. Immune response to antigen adsorbed to aluminum hydroxide particles: Effects of co-adsorption of ALF or ALFQ adjuvant to the aluminum-antigen complex.
Journal of controlled release : official journal of the Controlled Release Society.
2018 04; 275(?):12-19. doi:
10.1016/j.jconrel.2018.02.006. [PMID: 29432824] - Lanteng Wang, Wenmeng Jiang, Xing Shen, Xiangmei Li, Xin-An Huang, Zhenlin Xu, Yuanming Sun, Shun-Wan Chan, Lingwen Zeng, Sergei Alexandrovich Eremin, Hongtao Lei. Four Hapten Spacer Sites Modulating Class Specificity: Nondirectional Multianalyte Immunoassay for 31 β-Agonists and Analogues.
Analytical chemistry.
2018 02; 90(4):2716-2724. doi:
10.1021/acs.analchem.7b04684. [PMID: 29353474] - Young Hun Kim, Leibniz Hang, Jessica L Cifelli, David Sept, Michael Mayer, Jerry Yang. Frequency-Based Analysis of Gramicidin A Nanopores Enabling Detection of Small Molecules with Picomolar Sensitivity.
Analytical chemistry.
2018 02; 90(3):1635-1642. doi:
10.1021/acs.analchem.7b02961. [PMID: 29266927] - Agnieszka Sulima, Rashmi Jalah, Joshua F G Antoline, Oscar B Torres, Gregory H Imler, Jeffrey R Deschamps, Zoltan Beck, Carl R Alving, Arthur E Jacobson, Kenner C Rice, Gary R Matyas. A Stable Heroin Analogue That Can Serve as a Vaccine Hapten to Induce Antibodies That Block the Effects of Heroin and Its Metabolites in Rodents and That Cross-React Immunologically with Related Drugs of Abuse.
Journal of medicinal chemistry.
2018 01; 61(1):329-343. doi:
10.1021/acs.jmedchem.7b01427. [PMID: 29236495] - Atsuo Tanimoto, Yuichi Shinozaki, Yasuo Yamamoto, Yoshiaki Katsuda, Eriko Taniai-Riya, Kaoru Toyoda, Kochi Kakimoto, Yukari Kimoto, Wataru Amano, Noriko Konishi, Mikio Hayashi. A novel JAK inhibitor JTE-052 reduces skin inflammation and ameliorates chronic dermatitis in rodent models: Comparison with conventional therapeutic agents.
Experimental dermatology.
2018 01; 27(1):22-29. doi:
10.1111/exd.13370. [PMID: 28423239] - Seiichi Sakamoto, Waraporn Putalun, Sornkanok Vimolmangkang, Waranyoo Phoolcharoen, Yukihiro Shoyama, Hiroyuki Tanaka, Satoshi Morimoto. Enzyme-linked immunosorbent assay for the quantitative/qualitative analysis of plant secondary metabolites.
Journal of natural medicines.
2018 Jan; 72(1):32-42. doi:
10.1007/s11418-017-1144-z. [PMID: 29164507] - Yingying Wang, Jiwen Zhang, Mingxing Feng, Wenjun Wu, Zhaonong Hu. Insight into the Mode of Action of Celangulin V on the Transmembrane Potential of Midgut Cells in Lepidopteran Larvae.
Toxins.
2017 12; 9(12):. doi:
10.3390/toxins9120393. [PMID: 29210984] - Darcy S O Mora, Mo D Salman, Christopher A Myrick, Jack C Rhyan, Lowell A Miller, Ellen Marie Sætre, Douglas C Eckery. Evaluation of antibody response to an adjuvanted hapten-protein vaccine as a potential inhibitor of sexual maturation for farmed Atlantic salmon.
Fish & shellfish immunology.
2017 Dec; 71(?):255-263. doi:
10.1016/j.fsi.2017.08.038. [PMID: 28866277] - Masanobu Nagano, Nancy Carrillo, Nobumasa Otsubo, Wataru Hakamata, Hitoshi Ban, Roberta P Fuller, Nasir K Bashiruddin, Carlos F Barbas. In vivo programming of endogenous antibodies via oral administration of adaptor ligands.
Bioorganic & medicinal chemistry.
2017 11; 25(21):5952-5961. doi:
10.1016/j.bmc.2017.09.010. [PMID: 28988625] - Miles D Lange, Carl D Webster. The effect of temperature on the mucosal IgM antibody response to DNP-KLH in channel catfish (Ictalurus punctatus).
Fish & shellfish immunology.
2017 Nov; 70(?):493-497. doi:
10.1016/j.fsi.2017.09.026. [PMID: 28899776] - Rongzhi Wang, Linmao Zeng, Hang Yang, Yanfang Zhong, Juncheng Wang, Sumei Ling, Abdullah Farhan Saeed, Jun Yuan, Shihua Wang. Detection of okadaic acid (OA) using ELISA and colloidal gold immunoassay based on monoclonal antibody.
Journal of hazardous materials.
2017 Oct; 339(?):154-160. doi:
10.1016/j.jhazmat.2017.06.030. [PMID: 28648727] - Zongmin Zhao, Yun Hu, Theresa Harmon, Paul Pentel, Marion Ehrich, Chenming Zhang. Rationalization of a nanoparticle-based nicotine nanovaccine as an effective next-generation nicotine vaccine: A focus on hapten localization.
Biomaterials.
2017 Sep; 138(?):46-56. doi:
10.1016/j.biomaterials.2017.05.031. [PMID: 28551462] - Hong Wang, Xiaotian Zhang, Daidong Wang, Hongyang Sun, Yuexiang Lan, Haixiu Jiang, Shizhong Chen, Zongtao Lin. An on-line analytical approach for detecting haptens in Shuang-huang-lian powder injection.
Journal of chromatography. A.
2017 Sep; 1513(?):126-139. doi:
10.1016/j.chroma.2017.07.031. [PMID: 28739272] - Abdullah F U H Saeed, Sumei Ling, Jun Yuan, Shihua Wang. The Preparation and Identification of a Monoclonal Antibody against Domoic Acid and Establishment of Detection by Indirect Competitive ELISA.
Toxins.
2017 08; 9(8):. doi:
10.3390/toxins9080250. [PMID: 28817087] - Xiaoli Meng, Zaid Al-Attar, Fiazia S Yaseen, Rosalind Jenkins, Caroline Earnshaw, Paul Whitaker, Daniel Peckham, Neil S French, Dean J Naisbitt, B Kevin Park. Definition of the Nature and Hapten Threshold of the β-Lactam Antigen Required for T Cell Activation In Vitro and in Patients.
Journal of immunology (Baltimore, Md. : 1950).
2017 06; 198(11):4217-4227. doi:
10.4049/jimmunol.1700209. [PMID: 28438900] - M O Amali, A Sullivan, R E Jenkins, J Farrell, X Meng, L Faulkner, P Whitaker, D Peckham, B K Park, D J Naisbitt. Detection of drug-responsive B lymphocytes and antidrug IgG in patients with β-lactam hypersensitivity.
Allergy.
2017 Jun; 72(6):896-907. doi:
10.1111/all.13087. [PMID: 27861994] - Seiichi Sakamoto, Rika Nagamitsu, Gorawit Yusakul, Tomofumi Miyamoto, Hiroyuki Tanaka, Satoshi Morimoto. Ultrasensitive immunoassay for monocrotaline using monoclonal antibody produced by N, N'-carbonyldiimidazole mediated hapten-carrier protein conjugates.
Talanta.
2017 Jun; 168(?):67-72. doi:
10.1016/j.talanta.2017.03.028. [PMID: 28391867] - Natalia Vasylieva, Bogdan Barnych, Amy Rand, Bora Inceoglu, Shirley J Gee, Bruce D Hammock. Sensitive Immunoassay for Detection and Quantification of the Neurotoxin, Tetramethylenedisulfotetramine.
Analytical chemistry.
2017 05; 89(10):5612-5619. doi:
10.1021/acs.analchem.7b00846. [PMID: 28398746] - Kensaku Anraku, Shun Sato, Nicholas T Jacob, Lisa M Eubanks, Beverly A Ellis, Kim D Janda. The design and synthesis of an α-Gal trisaccharide epitope that provides a highly specific anti-Gal immune response.
Organic & biomolecular chemistry.
2017 Apr; 15(14):2979-2992. doi:
10.1039/c7ob00448f. [PMID: 28294277] - Takaaki Doi, Yoshiko Mizukawa, Yurie Shimoda, Yoshimi Yamazaki, Tetsuo Shiohara. Importance of Water Content of the Stratum Corneum in Mouse Models for Contact Hypersensitivity.
The Journal of investigative dermatology.
2017 01; 137(1):151-158. doi:
10.1016/j.jid.2016.08.031. [PMID: 27650608] - Noémie Scornet, Sandrine Delarue-Cochin, Marie Eliane Azoury, Maxime Le Mignon, Julie-Anne Chemelle, Emmanuel Nony, Bernard Maillère, Raphaël Terreux, Marc Pallardy, Delphine Joseph. Bioinspired Design and Oriented Synthesis of Immunogenic Site-Specifically Penicilloylated Peptides.
Bioconjugate chemistry.
2016 Nov; 27(11):2629-2645. doi:
10.1021/acs.bioconjchem.6b00393. [PMID: 27552359] - Pramodkumar D Jadhav, Youn Young Shim, Martin J T Reaney. Synthesis and Characterization of Site-Selective Orbitide-BSA Conjugate to Produce Antibodies.
Bioconjugate chemistry.
2016 10; 27(10):2346-2358. doi:
10.1021/acs.bioconjchem.6b00357. [PMID: 27626291] - Xiaoli Meng, Caroline J Earnshaw, Arun Tailor, Rosalind E Jenkins, James C Waddington, Paul Whitaker, Neil S French, Dean J Naisbitt, B Kevin Park. Amoxicillin and Clavulanate Form Chemically and Immunologically Distinct Multiple Haptenic Structures in Patients.
Chemical research in toxicology.
2016 10; 29(10):1762-1772. doi:
10.1021/acs.chemrestox.6b00253. [PMID: 27603302] - Guopeng Li, Liang Zhao, Feng Zhou, Jiaying Li, Yuan Xing, Tiangang Wang, Xilong Zhou, Baoping Ji, Wanpeng Ren. Monoclonal antibody production and indirect competitive enzyme-linked immunosorbent assay development of 3-methyl-quinoxaline-2-carboxylic acid based on novel haptens.
Food chemistry.
2016 Oct; 209(?):279-85. doi:
10.1016/j.foodchem.2016.04.083. [PMID: 27173564] - Adriana Ariza, Cristobalina Mayorga, María Salas, Inmaculada Doña, Ángela Martín-Serrano, Ezequiel Pérez-Inestrosa, Dolores Pérez-Sala, Antonio E Guzmán, María I Montañez, María J Torres. The influence of the carrier molecule on amoxicillin recognition by specific IgE in patients with immediate hypersensitivity reactions to betalactams.
Scientific reports.
2016 10; 6(?):35113. doi:
10.1038/srep35113. [PMID: 27731424] - Vincent Biajoux, Jessica Natt, Christelle Freitas, Nagham Alouche, Antoine Sacquin, Patrice Hemon, Françoise Gaudin, Nicolas Fazilleau, Marion Espéli, Karl Balabanian. Efficient Plasma Cell Differentiation and Trafficking Require Cxcr4 Desensitization.
Cell reports.
2016 09; 17(1):193-205. doi:
10.1016/j.celrep.2016.08.068. [PMID: 27681431] - Bo Zhang, Tiegui Nan, Zhilai Zhan, Liping Kang, Jian Yang, Yuan Yuan, Baomin Wang, Luqi Huang. Development of a monoclonal antibody-based enzyme-linked immunosorbent assay for luteoloside detection in Flos Lonicerae Japonicae.
Analytical and bioanalytical chemistry.
2016 Sep; 408(22):6053-61. doi:
10.1007/s00216-016-9396-0. [PMID: 26892641] - Sa Dong, Cunzheng Zhang, Xiao Zhang, Yuan Liu, Jianfeng Zhong, Yajing Xie, Chongxin Xu, Ying Ding, Liuquan Zhang, Xianjin Liu. Production and Characterization of Monoclonal Antibody Broadly Recognizing Cry1 Toxins by Use of Designed Polypeptide as Hapten.
Analytical chemistry.
2016 07; 88(14):7023-32. doi:
10.1021/acs.analchem.6b00429. [PMID: 27341419] - Jiebiao Guo, Wangpei Liu, Xianquan Lan, Hualong Chen, Zijun Xiao. Development and evaluation of an immunochromatographic strip for rapid screening of sildenafil-type compounds as illegal additives in functional foods.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.
2016 Jul; 33(7):1095-104. doi:
10.1080/19440049.2016.1203072. [PMID: 27310564] - Peter E Deak, Maura R Vrabel, Vincenzo J Pizzuti, Tanyel Kiziltepe, Basar Bilgicer. Nanoallergens: A multivalent platform for studying and evaluating potency of allergen epitopes in cellular degranulation.
Experimental biology and medicine (Maywood, N.J.).
2016 05; 241(9):996-1006. doi:
10.1177/1535370216644533. [PMID: 27188517] - Morgen Mhike, Justin M Hettick, Itai Chipinda, Brandon F Law, Toni A Bledsoe, Angela R Lemons, Ajay P Nayak, Brett J Green, Donald H Beezhold, Reuben H Simoyi, Paul D Siegel. Characterization and comparative analysis of 2,4-toluene diisocyanate and 1,6-hexamethylene diisocyanate haptenated human serum albumin and hemoglobin.
Journal of immunological methods.
2016 Apr; 431(?):38-44. doi:
10.1016/j.jim.2016.02.005. [PMID: 26853746] - Nicholas T Jacob, Jonathan W Lockner, Joel E Schlosburg, Beverly A Ellis, Lisa M Eubanks, Kim D Janda. Investigations of Enantiopure Nicotine Haptens Using an Adjuvanting Carrier in Anti-Nicotine Vaccine Development.
Journal of medicinal chemistry.
2016 Mar; 59(6):2523-9. doi:
10.1021/acs.jmedchem.5b01676. [PMID: 26918428] - Margaret E Brown, John C Browning. A Case of Psoriasis Replaced by Allergic Contact Dermatitis in a 12-Year-Old Boy.
Pediatric dermatology.
2016 Mar; 33(2):e125-6. doi:
10.1111/pde.12737. [PMID: 26646574] - Gorawit Yusakul, Seiichi Sakamoto, Thaweesak Juengwatanatrakul, Waraporn Putalun, Hiroyuki Tanaka, Satoshi Morimoto. Preparation and application of a monoclonal antibody against the isoflavone glycoside daidzin using a mannich reaction-derived hapten conjugate.
Phytochemical analysis : PCA.
2016 Jan; 27(1):81-8. doi:
10.1002/pca.2604. [PMID: 26689919] - Dan Cheng, Mingxing Feng, Yufei Ji, Wenjun Wu, Zhaonong Hu. Effects of Celangulin IV and V From Celastrus angulatus Maxim on Na+/K+-ATPase Activities of the Oriental Armyworm (Lepidoptera: Noctuidae).
Journal of insect science (Online).
2016; 16(1):. doi:
10.1093/jisesa/iew051. [PMID: 27324586]