(19E,21E,23E,25E,27E,29E,31Z)-33-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid (BioDeep_00000911127)
代谢物信息卡片
(19E,21E,23E,25E,27E,29E,31Z)-33-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
化学式: C47H73NO17 (923.4878248)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1C=CC=CC=CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC(C(CCC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O
InChI: InChI=1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16-
描述信息
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
D000890 - Anti-Infective Agents > D000935 - Antifungal Agents
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Paschalis Vergidis, Parham Sendi, Hassan B Alkhateeb, M Hong Nguyen. How do I manage refractory invasive pulmonary aspergillosis.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.
2024 Jun; 30(6):755-761. doi:
10.1016/j.cmi.2024.01.015. [PMID: 38286175] - Sebastian Janik, Rafal Luchowski, Ewa Grela, Wojciech Grudzinski, Wieslaw I Gruszecki. How Does the Antibiotic Amphotericin B Enter Membranes and What Does It Do There?.
The journal of physical chemistry letters.
2024 May; 15(18):4823-4827. doi:
10.1021/acs.jpclett.4c00496. [PMID: 38668706] - Hanna Stieber, Lara Junghanns, Hannah Wilhelm, Maria Batliner, Alexander Maximilian Aldejohann, Oliver Kurzai, Ronny Martin. The sphingolipid inhibitor myriocin increases Candida auris susceptibility to amphotericin B.
Mycoses.
2024 Apr; 67(4):e13723. doi:
10.1111/myc.13723. [PMID: 38551121] - Francelise Bridi Cavassin, Marcello Mihailenko Chaves Magri, Jose Ernesto Vidal, Fabianne Altruda de Moraes Costa Carlesse, Diego Rodrigues Falci, João Luís Baú-Carneiro, Giovanni Luís Breda, Fábio de Araújo Motta, Cássia Silva de Miranda Godoy, Renata de Bastos Ascenço Soares, Carla Sakuma De Oliveira, Ana Verena Almeida Mendes, Hugo Paz Morales, Patrícia Silva Montes, Mariane Taborda, Caroline Martins Rego, Maíra Araujo Félix, Paula Pacheco Katopodis, Julia Raquel da Silva do Ó, Mirela Pereira Lima Abrão, Talita Teles Teixeira Pereira, Flávio Queiroz-Telles. Effectiveness, Tolerability, and Safety of Different Amphotericin B Formulations in Invasive Fungal Infections: A Multicenter, Retrospective, Observational Study.
Clinical therapeutics.
2024 Apr; 46(4):322-337. doi:
10.1016/j.clinthera.2024.01.011. [PMID: 38403508] - Hendra Saputra, Muhammad Safaat, Pugoh Santoso, Rie Wakabayashi, Masahiro Goto, Toki Taira, Noriho Kamiya. Design of Protease-Responsive Antifungal Liposomal Formulation Decorated with a Lipid-Modified Chitin-Binding Domain.
International journal of molecular sciences.
2024 Mar; 25(7):. doi:
10.3390/ijms25073567. [PMID: 38612381] - ". [Multidisciplinary expert consensus on the clinical rational application of different formulations of amphotericin B (2024 edition)].
Zhonghua nei ke za zhi.
2024 Mar; 63(3):230-257. doi:
10.3760/cma.j.cn112138-20231122-00332. [PMID: 38448188] - Gabriel Silva Marques Borges, Thais Tunes Santos, Cristiane Monteiro Pinto, Frédéric Frézard, Verônica Freitas Blanco, Roberta Ondei, Stephen Rumbelow, Lucas Antônio Miranda Ferreira, Marta Marques Gontijo de Aguiar, Gisele Assis Castro Goulart. Distearoyl phosphatidylglycerol and dioleoyl phosphatidylglycerol increase the retention and reduce the toxicity of amphotericin B-loaded in nanoemulsions.
Nanomedicine (London, England).
2024 02; 19(5):383-396. doi:
10.2217/nnm-2023-0256. [PMID: 38293893] - Lei Chen, Xiuyun Tian, Lanyue Zhang, Wenzhao Wang, Pengjie Hu, Zhongyi Ma, Yeqi Li, Shibin Li, Zhenghao Shen, Xin Fan, Leixin Ye, Weixin Ke, Yao Wu, Guanghou Shui, Meng Xiao, Guang-Jun He, Ying Yang, Wenxia Fang, Fan Bai, Guojian Liao, Min Chen, Xiaorong Lin, Chong Li, Linqi Wang. Brain glucose induces tolerance of Cryptococcus neoformans to amphotericin B during meningitis.
Nature microbiology.
2024 Jan; ?(?):. doi:
10.1038/s41564-023-01561-1. [PMID: 38225460] - Neda Sharifi, Zahra Alitaneh, Sahar Asadi, Zeinab Vahidinia, Seyed Mohsen Aghaei Zarch, Ali Esmaeili, Saeid Bagheri-Mohammadi, Sajad Najafi, Yosra Mazhari. Developing nanosize carrier systems for Amphotericin-B: A review on the biomedical application of nanoparticles for the treatment of leishmaniasis and fungal infections.
Biotechnology journal.
2024 Jan; 19(1):e2300462. doi:
10.1002/biot.202300462. [PMID: 38073122] - Christina Schier, Martin C H Gruhlke, Georg Reucher, Alan J Slusarenko, Lothar Rink. Combating Black Fungus: Using Allicin as a Potent Antifungal Agent against Mucorales.
International journal of molecular sciences.
2023 Dec; 24(24):. doi:
10.3390/ijms242417519. [PMID: 38139348] - Armando Barragán-Reyes, Luis Esaú López Jácome, Diana Perales-Martínez, Alejandra Nava-Ruiz, María de Lourdes García Hernández, Patricia Cornejo-Juárez, Joaquín Rincón-Zuno, Adrián Camacho, Rafael Franco Cendejas, José M Feliciano Guzmán, Norma E Rivera-Martínez, Diego Ontañón-Zurita, Jesús Reséndiz-Sánchez, Eva Juárez-Hernández, Daniel Aguilar-Zapata. Fusariosis in Mexico: A 10-year retrospective series.
Medical mycology.
2023 Dec; 61(12):. doi:
10.1093/mmy/myad112. [PMID: 37944000] - Kashif Hussain, Abdul Jabbar, Khwaja Ali Hasan, Muneeb Ali, Zaheer Ul-Haq, Muhammad Raza Shah, Saeed Ahmad Khan, Md Abdur Rashid, Mohsin Kazi, Muhammad Naseer Abbas. Investigating the self-assembling of nicotinic hydrazide-based amphiphile into nano-range vesicles and its amphotericin B loading applications.
Drug delivery.
2023 Dec; 30(1):2174205. doi:
10.1080/10717544.2023.2174205. [PMID: 36785530] - Xiaoming Zhong, Jianqiong Yang, Hongyan Liu, Zhiwen Yang, Ping Luo. Potential lipid-based strategies of amphotericin B designed for oral administration in clinical application.
Drug delivery.
2023 Dec; 30(1):2161671. doi:
10.1080/10717544.2022.2161671. [PMID: 36601799] - Rogayeh Seify, Fahimeh Zahednezhad, Parvin Zakeri-Milani, Hadi Valizadeh. Amphotericin B liposomal formulation: applicable preparation methods, challenges, and tips.
Drug development and industrial pharmacy.
2023 Dec; 49(5):367-376. doi:
10.1080/03639045.2023.2215006. [PMID: 37249553] - Nandha Joyson, Anchal Pathak, Keerti Jain. One Platform Comparison of Polymeric and Lipidic Nanoparticles for the Delivery of Amphotericin B.
AAPS PharmSciTech.
2023 Nov; 24(8):226. doi:
10.1208/s12249-023-02672-y. [PMID: 37945925] - Arun Maji, Corinne P Soutar, Jiabao Zhang, Agnieszka Lewandowska, Brice E Uno, Su Yan, Yogesh Shelke, Ganesh Murhade, Evgeny Nimerovsky, Collin G Borcik, Andres S Arango, Justin D Lange, Jonnathan P Marin-Toledo, Yinghuan Lyu, Keith L Bailey, Patrick J Roady, Jordan T Holler, Anuj Khandelwal, Anna M SantaMaria, Hiram Sanchez, Praveen R Juvvadi, Gina Johns, Michael J Hageman, Joanna Krise, Teclegiorgis Gebremariam, Eman G Youssef, Ken Bartizal, Kieren A Marr, William J Steinbach, Ashraf S Ibrahim, Thomas F Patterson, Nathan P Wiederhold, David R Andes, Taras V Pogorelov, Charles D Schwieters, Timothy M Fan, Chad M Rienstra, Martin D Burke. Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal.
Nature.
2023 Nov; ?(?):. doi:
10.1038/s41586-023-06710-4. [PMID: 37938782] - Doaa M Abdel-Rahman, Basim Anwar Shehata Messiha, Fares E M Ali, Amany A Azouz. Regulation of renal nitric oxide and eNOS/iNOS expression by tadalafil participates in the mitigation of amphotericin B-induced renal injury: Down-regulation of NF-κB/iNOS/caspase-3 signaling.
Naunyn-Schmiedeberg's archives of pharmacology.
2023 Oct; ?(?):. doi:
10.1007/s00210-023-02787-w. [PMID: 37891258] - Carlos Ezquer-Garin, Gerardo Aguilar, Rafael Ferriols-Lisart, Manuel Alos-Almiñana. Validated HPLC-UV method for amphotericin B quantification in a critical patient receiving AmBisome and treated with extracorporeal replacement therapies.
Biomedical chromatography : BMC.
2023 Sep; ?(?):e5749. doi:
10.1002/bmc.5749. [PMID: 37727118] - Ilvana Caklovica Kucukkaya, Cafer Ikbal Gulsever, Ilyas Dolas, Gonca Erkose Genc, Mert Ahmet Kuskucu, Pulat Akin Sabanci, Zayre Erturan. First case of Rhinocladiella mackenziei brain abscess in Turkey: Case report and review of the literature.
Mycoses.
2023 09; 66(9):755-766. doi:
10.1111/myc.13601. [PMID: 37165906] - Kevin Ehemann, Andrés Contreras, Adriana Marcela Celis-Ramírez. In vitro sensitivity of Malassezia furfur isolates from HIV-positive and negative patients to antifungal agents.
Biomedica : revista del Instituto Nacional de Salud.
2023 Aug; 43(Sp. 1):120-131. doi:
10.7705/biomedica.6871. [PMID: 37721914] - Martin Hoenigl, Jeffrey D Jenks, Matthias Egger, Marcio Nucci, George R Thompson. Treatment of Fusarium Infection of the Central Nervous System: A Review of Past Cases to Guide Therapy for the Ongoing 2023 Outbreak in the United States and Mexico.
Mycopathologia.
2023 Aug; ?(?):. doi:
10.1007/s11046-023-00790-6. [PMID: 37653167] - David R Boulware, Mucunguzi Atukunda, Enock Kagimu, Abdu K Musubire, Andrew Akampurira, Lillian Tugume, Kenneth Ssebambulidde, John Kasibante, Laura Nsangi, Timothy Mugabi, Jane Gakuru, Sarah Kimuda, Derrick Kasozi, Suzan Namombwe, Isaac Turyasingura, Morris K Rutakingirwa, Edward Mpoza, Enos Kigozi, Conrad Muzoora, Jayne Ellis, Caleb P Skipper, Theresa Matkovits, Peter R Williamson, Darlisha A Williams, Ann Fieberg, Kathy H Hullsiek, Mahsa Abassi, Biyue Dai, David B Meya. Oral Lipid Nanocrystal Amphotericin B for Cryptococcal Meningitis: A Randomized Clinical Trial.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
2023 Aug; ?(?):. doi:
10.1093/cid/ciad440. [PMID: 37606364] - Daniela P Lage, Vívian T Martins, Danniele L Vale, Camila S Freitas, Breno L Pimenta, Gabriel J L Moreira, Fernanda F Ramos, Isabela A G Pereira, Raquel S Bandeira, Marcelo M de Jesus, Fernanda Ludolf, Grasiele S V Tavares, Miguel A Chávez-Fumagalli, Bruno M Roatt, Myron Christodoulides, Eduardo A F Coelho. The association between rLiHyp1 protein plus adjuvant and amphotericin B is an effective immunotherapy against visceral leishmaniasis in mice.
Acta tropica.
2023 Jul; ?(?):106986. doi:
10.1016/j.actatropica.2023.106986. [PMID: 37453579] - Joseph P Lynch, George G Zhanel. Part 2: mucormycosis: focus on therapy.
Expert review of anti-infective therapy.
2023 Jun; ?(?):1-12. doi:
10.1080/14787210.2023.2224564. [PMID: 37300820] - Kaushik Thanki, Tushar Date, Sanyog Jain. Enabling Oral Amphotericin B Delivery by Merging the Benefits of Prodrug Approach and Nanocarrier-Mediated Drug Delivery.
ACS biomaterials science & engineering.
2023 06; 9(6):2879-2890. doi:
10.1021/acsbiomaterials.0c01505. [PMID: 33587853] - Shabi Parvez, Ganesh Yadagiri, Kanika Arora, Aaqib Javaid, Anurag Kumar Kushwaha, Om Prakash Singh, Shyam Sundar, Shyam Lal Mudavath. Coalition of Biological Agent (Melatonin) With Chemotherapeutic Agent (Amphotericin B) for Combating Visceral Leishmaniasis via Oral Administration of Modified Solid Lipid Nanoparticles.
ACS biomaterials science & engineering.
2023 06; 9(6):2902-2910. doi:
10.1021/acsbiomaterials.1c00859. [PMID: 34463477] - Camila S Freitas, Samira S Santiago, Daniela P Lage, Luciana M R Antinarelli, Fabrício M Oliveira, Danniele L Vale, Vívian T Martins, Lícia N D Magalhaes, Raquel S Bandeira, Fernanda F Ramos, Isabela A G Pereira, Marcelo M de Jesus, Fernanda Ludolf, Grasiele S V Tavares, Adilson V Costa, Rafaela S Ferreira, Elaine S Coimbra, Róbson R Teixeira, Eduardo A F Coelho. In vitro evaluation of antileishmanial activity, mode of action and cellular response induced by vanillin synthetic derivatives against Leishmania species able to cause cutaneous and visceral leishmaniasis.
Experimental parasitology.
2023 May; 251(?):108555. doi:
10.1016/j.exppara.2023.108555. [PMID: 37247802] - Rong-Jing Dong, Jun Li, Yi Zhang, Jia-Sheng Li, Lu-Hui Yang, Yi-Qun Kuang, Rui-Rui Wang, Yu-Ye Li. Thalidomide promotes NLRP3/caspase-1-mediated pyroptosis of macrophages in Talaromyces marneffei infection.
Microbial pathogenesis.
2023 May; ?(?):106168. doi:
10.1016/j.micpath.2023.106168. [PMID: 37224982] - Daniela Peruzzu, Katia Fecchi, Giulietta Venturi, Maria Cristina Gagliardi. Repurposing Amphotericin B and Its Liposomal Formulation for the Treatment of Human Mpox.
International journal of molecular sciences.
2023 May; 24(10):. doi:
10.3390/ijms24108896. [PMID: 37240241] - Jennifer C Chan, Jonathan Dear, Carrie Palm, Krystle Reagan. Incidence of acute kidney injury in dogs with systemic mycotic infections treated with amphotericin B (1996-2020).
Journal of veterinary internal medicine.
2023 May; ?(?):. doi:
10.1111/jvim.16728. [PMID: 37148178] - Kristelle Hughes, Thanh Binh Le, Patrick Van Der Smissen, Donatienne Tyteca, Marie-Paule Mingeot-Leclercq, Joëlle Quetin-Leclercq. The Antileishmanial Activity of Eugenol Associated with Lipid Storage Reduction Rather Than Membrane Properties Alterations.
Molecules (Basel, Switzerland).
2023 May; 28(9):. doi:
10.3390/molecules28093871. [PMID: 37175277] - ". [Expert consensus on rational clinical application of amphotericin B deoxycholate (2022)].
Zhonghua yi xue za zhi.
2023 Apr; 103(16):1173-1183. doi:
10.3760/cma.j.cn112137-20221206-02578. [PMID: 37087401] - Kyle Lethcoe, Colin A Fox, Isabel Moh, Matthew Swackhamer, Michael Karo, Ryan Lockhart, Robert O Ryan. Formulation and Characterization of Bioactive Agent Containing Nanodisks.
Journal of visualized experiments : JoVE.
2023 03; ?(193):. doi:
10.3791/65145. [PMID: 37010309] - Saifuddin Sheikh, Ateeq Ahmad, Shoukath M Ali, Mahesh Paithankar, Ronak Patel, Shushil Chuadhari, Purvi M Dave, Mamta V Bhomia, Jagruti Y Desai, Atul Munshi, Meenakshi N Shah, Kirankumar R Desai, Swati A Dongre, Shraddha A Walvekar, Imran Ahmad. Lipid-based amphotericin B gel treatment eradicates vulvovaginal candidiasis in patients who failed to azole therapy.
Archives of dermatological research.
2023 Mar; ?(?):. doi:
10.1007/s00403-023-02583-9. [PMID: 36856855] - Xiaona Liu, Ragna Berthelsen, Daniel Bar-Shalom, Tania Kjellerup Lind, James Doutch, Anette Müllertz. Amphotericin B and monoacyl-phosphatidylcholine form a stable amorphous complex.
International journal of pharmaceutics.
2023 Feb; 633(?):122601. doi:
10.1016/j.ijpharm.2023.122601. [PMID: 36632922] - Amany A Azouz, Doaa M Abdel-Rahman, Basim Anwar Shehata Messiha. Balancing renal Ang-II/Ang-(1-7) by xanthenone; an ACE2 activator; contributes to the attenuation of Ang-II/p38 MAPK/NF-κB p65 and Bax/caspase-3 pathways in amphotericin B-induced nephrotoxicity in rats.
Toxicology mechanisms and methods.
2023 Feb; ?(?):1-11. doi:
10.1080/15376516.2023.2177218. [PMID: 36747322] - Francelise Bridi Cavassin, Jose Ernesto Vidal, João Luiz Baú-Carneiro, Cássia Silva de Miranda Godoy, Renata de Bastos Ascenço Soares, Marcello Mihailenko Chaves Magri, Diego Rodrigues Falci, Carla Sakuma De Oliveira, Ana Verena Almeida Mendes, Giovanni Luís Breda, Caroline Martins Rego, Maíra Araujo Félix, Paula Pacheco Katopodis, Julia Raquel da Silva do Ó, Mirela Pereira Lima Abrão, Mariane Taborda, Talita Teles Teixeira Pereira, Flávio Queiroz-Telles. Characteristics, mortality, associated variables with death, and therapeutic response among HIV-positive, solid organ transplant (SOT), and non-HIV-positive/non-transplant (NHNT) patients with cryptococcosis: First multicenter cohort study in Brazil.
Medical mycology.
2023 Feb; 61(2):. doi:
10.1093/mmy/myad011. [PMID: 36708168] - Letícia Kraft, Victoria Stadler Tasca Ribeiro, Geiziane Aparecida Gonçalves, Paula Hansen Suss, Felipe Francisco Tuon. Comparison of amphotericin B lipid complex, deoxycholate amphotericin B, fluconazole, and anidulafungin activity against Candida albicans biofilm isolated from breakthrough candidemia.
Enfermedades infecciosas y microbiologia clinica (English ed.).
2023 Jan; ?(?):. doi:
10.1016/j.eimce.2022.07.009. [PMID: 36707288] - Joris R Delanghe, Jonas Himpe, Jerina Boelens, Dominique Benoit, Bram Gadeyne, Marijn M Speeckaert, Frederick Verbeke. C-reactive protein interacts with amphotericin B liposomes and its potential clinical consequences.
Clinical chemistry and laboratory medicine.
2023 Jan; ?(?):. doi:
10.1515/cclm-2022-1213. [PMID: 36691951] - Julia Borzyszkowska-Bukowska, Jacek Czub, Paweł Szczeblewski, Tomasz Laskowski. Antibiotic-sterol interactions provide insight into the selectivity of natural aromatic analogues of amphotericin B and their photoisomers.
Scientific reports.
2023 Jan; 13(1):762. doi:
10.1038/s41598-023-28036-x. [PMID: 36641464] - Phawanan Sawangchan, Francisco Alexandrino Júnior, Éverton N Alencar, Eryvaldo S T Egito, Lee E Kirsch. The role of aggregation and ionization in the chemical instability of Amphotericin B in aqueous methanol.
International journal of pharmaceutics.
2023 Jan; 632(?):122586. doi:
10.1016/j.ijpharm.2023.122586. [PMID: 36623739] - Li Zhang, Jinzhou Xiao, Mingwei Du, Wenzhi Lei, Weiwei Yang, Xiaochun Xue. Post-translational modifications confer amphotericin B resistance in Candida krusei isolated from a neutropenic patient.
Frontiers in immunology.
2023; 14(?):1148681. doi:
10.3389/fimmu.2023.1148681. [PMID: 36936926] - Zaid Shaikh, Abhijeet Mishra, Srinivas Chadaram, Chappity Preetam, Reetika Biswas, Asutosh Adhikari, Alamelu Alagappan, Pradipta K Parida, Pradeep Pradhan, Dillip Kumar Samal, Sudipta Mahakud, Vinay Hallur, Anindya Nayak, Krishna Kinkar Das, Swagata Chakraborty, Prity Sharma, Aswathi Kallyadan Veetil, Vinusree Karakkandy, Yash Mittal, Kalyana Sundaram Chithambaram, Anurita Swarup, Swathi Chenniappan, Anwer Shah. To evaluate the efficacy of topical anti-fungal therapy in postoperative cases of COVID Associated Mucormycosis (CAM): A single-blinded randomized control trial.
American journal of otolaryngology.
2022 Dec; 44(2):103702. doi:
10.1016/j.amjoto.2022.103702. [PMID: 36521349] - Adetola H Adewole, Ibukun M Famuyide, Lyndy J McGaw, Mamoalosi A Selepe, Natasha October. Antifungal Compounds from the Leaves of Rhynchosia minima.
Chemistry & biodiversity.
2022 Dec; 19(12):e202200837. doi:
10.1002/cbdv.202200837. [PMID: 36305375] - Masato Tashiro, Yoko Obata, Takahiro Takazono, Yuki Ota, Tomotaro Wakamura, Yui Shiozawa, Ai Tsuyuki, Taiga Miyazaki, Tomoya Nishino, Koichi Izumikawa. Association between fluid infusions and the recovery from acute kidney injury in patients administered liposomal amphotericin B: a nationwide observational study.
Renal failure.
2022 Dec; 44(1):282-292. doi:
10.1080/0886022x.2022.2036618. [PMID: 35172680] - Suhair Sunoqrot, Amal G Al-Bakri, Lina Hasan Ibrahim, Neda'a Aldaken. Amphotericin B-Loaded Plant-Inspired Polyphenol Nanoparticles Enhance Its Antifungal Activity and Biocompatibility.
ACS applied bio materials.
2022 11; 5(11):5156-5164. doi:
10.1021/acsabm.2c00537. [PMID: 36241585] - Hiromasa Taniguchi, Yugo Ishimime, Kosuke Minamihata, Pugoh Santoso, Takuya Komada, Hendra Saputra, Kazuki Uchida, Masahiro Goto, Toki Taira, Noriho Kamiya. Liposomal Amphotericin B Formulation Displaying Lipid-Modified Chitin-Binding Domains with Enhanced Antifungal Activity.
Molecular pharmaceutics.
2022 11; 19(11):3906-3914. doi:
10.1021/acs.molpharmaceut.2c00388. [PMID: 36066555] - Courtney Smith, Soo Chan Lee. Current treatments against mucormycosis and future directions.
PLoS pathogens.
2022 10; 18(10):e1010858. doi:
10.1371/journal.ppat.1010858. [PMID: 36227854] - Ertan Sal, Jannik Stemler, Jon Salmanton-García, Iker Falces-Romero, László Kredics, Elisabeth Meyer, Benjamin Würstl, Cornelia Lass-Flörl, Zdenek Racil, Nikolay Klimko, Simone Cesaro, Anupma Jyoti Kindo, Hilmar Wisplinghoff, Philipp Koehler, Oliver A Cornely, Danila Seidel. Invasive Trichoderma spp. infections: clinical presentation and outcome of cases from the literature and the FungiScope® registry.
The Journal of antimicrobial chemotherapy.
2022 09; 77(10):2850-2858. doi:
10.1093/jac/dkac235. [PMID: 35929089] - Svetlana S Efimova, Vera A Martynyuk, Anastasiia A Zakharova, Natalia M Yudintceva, Nikita M Chernov, Igor P Yakovlev, Olga S Ostroumova. Chromone-Containing Allylmorpholines Influence Ion Channels in Lipid Membranes via Dipole Potential and Packing Stress.
International journal of molecular sciences.
2022 Sep; 23(19):. doi:
10.3390/ijms231911554. [PMID: 36232854] - Aakriti Singh, Ganesh Yadagiri, Aaqib Javaid, Krishna Kumar Sharma, Anurag Verma, Om Prakash Singh, Shyam Sundar, Shyam Lal Mudavath. Hijacking the intrinsic vitamin B12 pathway for the oral delivery of nanoparticles, resulting in enhanced in vivo anti-leishmanial activity.
Biomaterials science.
2022 Sep; 10(19):5669-5688. doi:
10.1039/d2bm00979j. [PMID: 36017751] - Daniela Peruzzu, Antonello Amendola, Giulietta Venturi, Valeria de Turris, Giulia Marsili, Claudia Fortuna, Katia Fecchi, Maria Cristina Gagliardi. Zika Virus Exploits Lipid Rafts to Infect Host Cells.
Viruses.
2022 09; 14(9):. doi:
10.3390/v14092059. [PMID: 36146865] - Orfa Inés Contreras Martínez, Alberto Angulo Ortíz, Gilmar Santafé Patiño. Mechanism of Antifungal Action of Monoterpene Isoespintanol against Clinical Isolates of Candida tropicalis.
Molecules (Basel, Switzerland).
2022 Sep; 27(18):. doi:
10.3390/molecules27185808. [PMID: 36144544] - Maksim A Burkin, Yuri A Surovoy, Vera G Arzumanian, Inna A Galvidis. Development and application of amphotericin B immunoassay for pharmacokinetic studies and therapeutic drug monitoring in critically ill patients.
Journal of pharmaceutical and biomedical analysis.
2022 Sep; 218(?):114875. doi:
10.1016/j.jpba.2022.114875. [PMID: 35679709] - Pugoh Santoso, Takuya Komada, Yugo Ishimine, Hiromasa Taniguchi, Kosuke Minamihata, Masahiro Goto, Toki Taira, Noriho Kamiya. Preparation of amphotericin B-loaded hybrid liposomes and the integration of chitin-binding proteins for enhanced antifungal activity.
Journal of bioscience and bioengineering.
2022 Sep; 134(3):259-263. doi:
10.1016/j.jbiosc.2022.06.005. [PMID: 35781189] - Antonio Lipa Castro, Sébastien Pomel, Catherine Cailleau, Natalie Fournier, Indira Dennemont, Philippe M Loiseau, Gillian Barratt. Pharmacokinetics, biodistribution, and activity of Amphotericin B-loaded nanocochleates on the Leishmania donovani murine visceral leishmaniasis model.
International journal of pharmaceutics.
2022 Aug; 624(?):121985. doi:
10.1016/j.ijpharm.2022.121985. [PMID: 35820519] - X M Ding, Y Y Qi, K Y Zhang, G Tian, S P Bai, J P Wang, H W Peng, L Lv, Y Xuan, Q F Zeng. Corn distiller's dried grains with solubles as an alternative ingredient to corn and soybean meal in Pekin duck diets based on its predicted AME and the evaluated standardized ileal digestibility of amino acids.
Poultry science.
2022 Aug; 101(8):101974. doi:
10.1016/j.psj.2022.101974. [PMID: 35760004] - Amirreza Veisi, Abbas Bagheri, Mohammad Eshaghi, Mohamad Hasan Rikhtehgar, Mozhgan Rezaei Kanavi, Reza Farjad. Rhino-orbital mucormycosis during steroid therapy in COVID-19 patients: A case report.
European journal of ophthalmology.
2022 Jul; 32(4):NP11-NP16. doi:
10.1177/11206721211009450. [PMID: 33843287] - Raju Shivarathri, Sabrina Jenull, Manju Chauhan, Ashutosh Singh, Rounik Mazumdar, Anuradha Chowdhary, Karl Kuchler, Neeraj Chauhan. Comparative Transcriptomics Reveal Possible Mechanisms of Amphotericin B Resistance in Candida auris.
Antimicrobial agents and chemotherapy.
2022 06; 66(6):e0227621. doi:
10.1128/aac.02276-21. [PMID: 35652307] - Jonathan P Huggins, Robert Pease, Kelly Stanly, Adrienne Workman, John Reynolds, Barbara D Alexander. Safety of Inhaled Amphotericin B Lipid Complex as Antifungal Prophylaxis in Lung Transplant Recipients.
Antimicrobial agents and chemotherapy.
2022 06; 66(6):e0028322. doi:
10.1128/aac.00283-22. [PMID: 35506698] - Akshay Gopinathan Nair, Tarjani Vivek Dave. Transcutaneous retrobulbar injection of amphotericin B in rhino-orbital-cerebral mucormycosis: a review.
Orbit (Amsterdam, Netherlands).
2022 Jun; 41(3):275-286. doi:
10.1080/01676830.2021.1990351. [PMID: 34720026] - Maraine Catarina Tadini, Fernanda Santos Fernandes, Saulo Duarte Ozelin, Matheus Reis Santos de Melo, Ana Luiza Mansur, Thaís Bueno de Toledo, Nayara Cristina Perez de Albuquerque, Denise Crispim Tavares, Franciane Marquele-Oliveira, Anderson Rodrigo Moraes de Oliveira. Pharmacokinetic study of AmB-NP-GR: A new granule form with amphotericin B to treat leishmaniasis and fungal infections.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2022 Jun; 173(?):106173. doi:
10.1016/j.ejps.2022.106173. [PMID: 35331860] - Bo Wang, Yuerong Wang, Luwen Zhang, Fanbo Lu, Min Zhang, Yuanhong Xu. Surveillance Study of Epidemiology, Antifungal Susceptibility and Risk Factors of Invasive Candidiasis in Critically ill Patients.
Clinical laboratory.
2022 Jun; 68(6):. doi:
10.7754/clin.lab.2021.211001. [PMID: 35704741] - Rula M Darwish, Mohammad AlMasri, Mahmoud M Al-Masri. Mucormycosis: The hidden and forgotten disease.
Journal of applied microbiology.
2022 Jun; 132(6):4042-4057. doi:
10.1111/jam.15487. [PMID: 35156271] - Reshma P Chavan, Shivraj M Ingole, Hamna Abdul Nazir, Wilson V Desai, Gajanan S Kanchewad. Mucormycosis in COVID-19 pandemic: study at tertiary hospital in India.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery.
2022 Jun; 279(6):3201-3210. doi:
10.1007/s00405-022-07282-1. [PMID: 35122509] - Pugoh Santoso, Kosuke Minamihata, Yugo Ishimine, Hiromasa Taniguchi, Takuya Komada, Ryo Sato, Masahiro Goto, Tomoya Takashima, Toki Taira, Noriho Kamiya. Enhancement of the Antifungal Activity of Chitinase by Palmitoylation and the Synergy of Palmitoylated Chitinase with Amphotericin B.
ACS infectious diseases.
2022 05; 8(5):1051-1061. doi:
10.1021/acsinfecdis.2c00052. [PMID: 35471825] - Mahzad Erami, Omid Raiesi, Mansooreh Momen-Heravi, Muhammad Ibrahim Getso, Mojtaba Fakhrehi, Narges Mehri, Mohammad Yarahmadi, Sasan Amiri, Vahid Raissi, Seyed Jamal Hashemi. Clinical impact of Candida respiratory tract colonization and acute lung infections in critically ill patients with COVID-19 pneumonia.
Microbial pathogenesis.
2022 May; 166(?):105520. doi:
10.1016/j.micpath.2022.105520. [PMID: 35405278] - Lais Alonso, Laryssa Ketelyn Lima Pimenta, André Kipnis, Antonio Alonso. Mycobacterium abscessus cell wall and plasma membrane characterization by EPR spectroscopy and effects of amphotericin B, miltefosine and nerolidol.
Biochimica et biophysica acta. Biomembranes.
2022 05; 1864(5):183872. doi:
10.1016/j.bbamem.2022.183872. [PMID: 35085568] - D Kaushal, N Rajan, K Soni, A Sharma, B Choudhury, T Yadav, P Khera, P Gupta, N Kaur, A Goyal. Reducing mortality in mucormycosis of the head and neck in diabetic patients: A CARE case series.
European annals of otorhinolaryngology, head and neck diseases.
2022 May; 139(3):146-152. doi:
10.1016/j.anorl.2021.06.015. [PMID: 34489194] - Sumit Mrig, Kabir Sardana, Pooja Arora, Vineet Narula, Sandeep Arora, Amrit Kapoor, Ritu Raj Baruah, Poornima Sen, Shweta Agarwal, Soumya Sachdeva, Arun Dewan, Sanjeet Panesar. Adjunctive use of saturated solution of potassium iodide (SSKI) with liposomal amphotericin B (L-AMB) in mucormycosis achieves favorable response, shortened dose and duration of amphotericin: A retrospective study from a COVID-19 tertiary care center.
American journal of otolaryngology.
2022 May; 43(3):103465. doi:
10.1016/j.amjoto.2022.103465. [PMID: 35429848] - Wei-Chun Huang, Mei-Tzu Wang, Tai-Shuan Lai, Kuo-Hua Lee, Shih-Chieh Shao, Chien-Hao Chen, Chien-Hao Su, Yih-Ting Chen, Junne-Ming Sung, Yung-Chang Chen. Nephrotoxins and acute kidney injury - The consensus of the Taiwan acute kidney injury Task Force.
Journal of the Formosan Medical Association = Taiwan yi zhi.
2022 May; 121(5):886-895. doi:
10.1016/j.jfma.2021.12.007. [PMID: 34998658] - Sema Tamer Kaderli, Aylin Karalezli, Burak Ekrem Çitil, Ali Osman Saatci. Endogenous Fungal Endophthalmitis in a Patient Admitted to Intensive Care and Treated with Systemic Steroid for COVID-19.
Turkish journal of ophthalmology.
2022 04; 52(2):139-141. doi:
10.4274/tjo.galenos.2022.04324. [PMID: 35481735] - Aakriti Singh, Ganesh Yadagiri, Manorma Negi, Anurag Kumar Kushwaha, Om Prakash Singh, Shyam Sundar, Shyam Lal Mudavath. Carboxymethyl chitosan modified lipid nanoformulations as a highly efficacious and biocompatible oral anti-leishmanial drug carrier system.
International journal of biological macromolecules.
2022 Apr; 204(?):373-385. doi:
10.1016/j.ijbiomac.2022.02.006. [PMID: 35149096] - Yusri Abdel-Hafez, Hani Siaj, Mohammad Janajri, Yazan Abu-Baker, Zaher Nazzal, Zakaria Hamdan, Rabee Adwan, Banan M Aiesh, Ahmad I Anaya. Tolerability and epidemiology of nephrotoxicity associated with conventional amphotericin B therapy: a retrospective study in tertiary care centers in Palestine.
BMC nephrology.
2022 04; 23(1):132. doi:
10.1186/s12882-022-02770-2. [PMID: 35382766] - Xueyuan Zhang, Yuhuan Ji, Jinzhi Liu, Ji Liu, Chunlei Li, Laixin Wang, Min Meng, Limei Zhao. Regulated bioanalysis of liposomal amphotericin B to support pharmacokinetic studies of liposomal drugs.
Bioanalysis.
2022 Apr; 14(7):421-439. doi:
10.4155/bio-2021-0281. [PMID: 35264007] - Prashant Gupta, Hardeep Singh Malhotra, Priyamvada Saxena, Riddhi Singh, Deeksha Shukla, Mohd Saqib Hasan, Veerendra Verma, Gopa Banerjee, Bipin Puri, Himanshu Dandu. Utility of itraconazole and terbinafine in mucormycosis: a proof-of-concept analysis.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research.
2022 04; 70(4):914-918. doi:
10.1136/jim-2021-002179. [PMID: 35078866] - Somenath Roy Chowdhury, Subhendu K Das, Bijoylaxmi Banerjee, Srijita Paul Chowdhuri, Hemanta K Majumder, Benu Brata Das. TDP1 knockout Leishmania donovani accumulate topoisomerase 1-linked DNA damage and are hypersensitive to clinically used antileishmanial drugs.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2022 04; 36(4):e22265. doi:
10.1096/fj.202101668rr. [PMID: 35319800] - Prabhakar Singh, Abhishek Gupta, Sravani Reddy Sanepalli, Amit Raj. Transcutaneous retrobulbar amphotericin-B (TRAMB) injection in orbital mucormycosis.
BMJ case reports.
2022 Mar; 15(3):. doi:
10.1136/bcr-2021-246307. [PMID: 35361668] - Emma Littlehales, Rebecca Teague, Dale Andrew, Emily Yassaie. Mucormycosis in Burns: A Review.
Journal of burn care & research : official publication of the American Burn Association.
2022 03; 43(2):353-360. doi:
10.1093/jbcr/irab236. [PMID: 34874443] - Min Pan, Qirui Wang, Yulong Liu, Nan Xiao, Xiaojia Niu, Daqiang Wu, Tianming Wang, Guiming Yan, Jing Shao. Paeonol enhances treatment of fluconazole and amphotericin B against oropharyngeal candidiasis through HIF-1α related IL-17 signaling.
Medical mycology.
2022 Mar; 60(3):. doi:
10.1093/mmy/myac011. [PMID: 35099003] - María Cruz Soriano, Gabriela Narváez-Chávez, Marina López-Olivencia, Jesús Fortún, Raúl de Pablo. Inhaled amphotericin B lipid complex for prophylaxis against COVID-19-associated invasive pulmonary aspergillosis.
Intensive care medicine.
2022 03; 48(3):360-361. doi:
10.1007/s00134-021-06603-y. [PMID: 34940907] - Lakshmi B Ramamurthy, Ridhi Bhandari, Savitha Kanakpur, P Thejaswini. Outcome of transcutaneous retrobulbar injection of liposomal amphotericin B in post-COVID-19 rhino-orbito-cerebral mucormycosis: Our experience.
Indian journal of ophthalmology.
2022 03; 70(3):1019-1024. doi:
10.4103/ijo.ijo_2356_21. [PMID: 35225564] - Satish Swain, Animesh Ray, Naveet Wig, Anjan Trikha. Desensitization to liposomal amphotericin B after anaphylaxis in a patient with COVID-19-associated mucormycosis - A case with review of literature.
Indian journal of pharmacology.
2022 Mar; 54(2):150-152. doi:
10.4103/ijp.ijp_883_21. [PMID: 35546469] - Emanuel Paula Magalhães, Brenna Pinheiro Silva, Natália Luna Aires, Lyanna Rodrigues Ribeiro, Arif Ali, Mariana Maciel Cavalcanti, João Victor Serra Nunes, Tiago Lima Sampaio, Ramon Róseo Paula Pessoa Bezerra de Menezes, Alice Maria Costa Martins. (-)-α-Bisabolol as a protective agent against epithelial renal cytotoxicity induced by amphotericin B.
Life sciences.
2022 Feb; 291(?):120271. doi:
10.1016/j.lfs.2021.120271. [PMID: 34974077] - Munazza Tamkeen Fatima, Zeyaul Islam, Ejaj Ahmad, Mehboob Hoque, Marriam Yamin. Plasma Bead Entrapped Liposomes as a Potential Drug Delivery System to Combat Fungal Infections.
Molecules (Basel, Switzerland).
2022 Feb; 27(3):. doi:
10.3390/molecules27031105. [PMID: 35164370] - Rodrigo C Bassi, Marcelo F G Boriollo. Amphotericin B, fluconazole, and nystatin as development inhibitors of Candida albicans biofilms on a dental prosthesis reline material: Analytical models in vitro.
The Journal of prosthetic dentistry.
2022 Feb; 127(2):320-330. doi:
10.1016/j.prosdent.2020.10.018. [PMID: 33279153] - Anna Lango-Maziarz, Magdalena Kołaczkowska, Piotr Siondalski, Maciej Duda, Michał Dubowik, Romuald Lango. Colon mucormycosis with renal spread resistant to lipid complex amphotericin and isavuconazole treatment in a heart transplant recipient.
Polish archives of internal medicine.
2022 01; 132(1):. doi:
10.20452/pamw.16156. [PMID: 34851070] - Amrita Chakrabarti, Chintam Narayana, Nishant Joshi, Swati Garg, Lalit C Garg, Anand Ranganathan, Ram Sagar, Soumya Pati, Shailja Singh. Metalloprotease Gp63-Targeting Novel Glycoside Exhibits Potential Antileishmanial Activity.
Frontiers in cellular and infection microbiology.
2022; 12(?):803048. doi:
10.3389/fcimb.2022.803048. [PMID: 35601095] - V N Kolesnokov, A A Khanamirov, N V Boiko, M A Lapin, S D Stagniev. [Postcovid sino-orbital mucormycosis: a case report].
Vestnik otorinolaringologii.
2022; 87(3):107-111. doi:
10.17116/otorino202287031107. [PMID: 35818954] - Beatriz Santana Borges, Gislayne de Paula Bueno, Fernanda Tomiotto-Pellissier, Fabiano Borges Figueiredo, Lia Carolina Soares Medeiros. In vitro anti-Leishmania activity of triclabendazole and its synergic effect with amphotericin B.
Frontiers in cellular and infection microbiology.
2022; 12(?):1044665. doi:
10.3389/fcimb.2022.1044665. [PMID: 36699729] - Max Melchers, Barbara Festen, Bianca M den Dekker, Eline R M Mooren, Annelien L van Binsbergen, Sjoerd H W van Bree, Moniek Heusinkveld, Roel Schellaars, Jochem B Buil, Paul E Verweij, Arthur R H van Zanten. A 67-Year-Old Male Patient With COVID-19 With Worsening Respiratory Function and Acute Kidney Failure.
Chest.
2022 01; 161(1):e5-e11. doi:
10.1016/j.chest.2021.08.045. [PMID: 35000717] - Hermineh Gholizadeh, Fatemeh Ghaffarifar, Abdolhossein Dalimi, Mohammad Saaid Dayer. In vitro and in vivo effects of natural honey on Leishmania major.
Annals of parasitology.
2022; 68(1):71-76. doi:
10.17420/ap6801.410. [PMID: 35491675] - Huiping Jiang, Jianqun Xiong, Lihua Tan, Ping Jin, Yi Sun, Lianjuan Yang, Jingwen Tan. In Vitro Interactions of Antifungal Agents and Everolimus Against Aspergillus Species.
Frontiers in cellular and infection microbiology.
2022; 12(?):936814. doi:
10.3389/fcimb.2022.936814. [PMID: 35865820] - Ramesh Murthy, Aadhyaa Bagchi, Yogita Gote, Sanjay Desai. Retrobulbar injection of amphotericin B using intravenous cannula for post-COVID-19 rhino-orbital mucormycosis.
Indian journal of ophthalmology.
2022 Jan; 70(1):302-305. doi:
10.4103/ijo.ijo_1511_21. [PMID: 34937263] - T H Geersing, E J F Franssen, P E Spronk, H J M van Kan, M den Reijer, P H J van der Voort. Nephrotoxicity of continuous amphotericin B in critically ill patients with abdominal sepsis: a retrospective analysis with propensity score matching.
The Journal of antimicrobial chemotherapy.
2021 12; 77(1):246-252. doi:
10.1093/jac/dkab372. [PMID: 34613383] - N A Kireeva, S S Sokolov, E A Smirnova, K V Galkina, F F Severin, D A Knorre. Adaptive Role of Cell Death in Yeast Communities Stressed with Macrolide Antifungals.
mSphere.
2021 12; 6(6):e0074521. doi:
10.1128/msphere.00745-21. [PMID: 34787448] - Victória Soares Soeiro, Ricardo Silva-Carvalho, Daniela Martins, Pier Parpot, Denise Grotto, Marco Vinicius Chaud, Francisco Miguel Portela da Gama, Angela Faustino Jozala. Alginate-amphotericin B nanocomplexes covered by nanocrystals from bacterial cellulose: physico-chemical characterization and in vitro toxicity.
Scientific reports.
2021 12; 11(1):23944. doi:
10.1038/s41598-021-03264-1. [PMID: 34907234] - Melisa A Quinteros, Juan Tolosa, Joaquín C García-Martínez, Paulina L Páez, María G Paraje. Synergic activity of oligostyrylbenzenes with amphotericin B against Candida tropicalis biofilms.
Yeast (Chichester, England).
2021 12; 38(12):634-645. doi:
10.1002/yea.3672. [PMID: 34596268] - Fatma Devrim, İlknur Çağlar, Sultan Okur Acar, Şeyma Akkuş, Nida Dinçel, Ebru Yılmaz, Neryal Tahta, Bengü Demirağ, Tuba Hilkay Karapınar, Salih Gözmen, Yeşim Oymak, Canan Vergin, Nuri Bayram, İlker Devrim. Evaluation of renal effects of liposomal amphotericin B in children with malignancies with KDIGO and RIFLE criteria.
Nephrologie & therapeutique.
2021 Dec; 17(7):507-511. doi:
10.1016/j.nephro.2021.06.007. [PMID: 34535406]