Glutamic acid, monosodium salt (BioDeep_00000910905)
代谢物信息卡片
Glutamic acid, monosodium salt
化学式: C5H8NNaO4 (169.03510079999998)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(CC(=O)O)C(C(=O)[O-])N.[Na+]
InChI: /q
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Fuming He, Baojun Gao, Xin Cheng, Jiao Zhai, Xinqing Zhang, Chuanlun Yang, Tian Jiewei. High-level production of poly-γ-glutamic acid by a newly isolated Bacillus sp. YJY-8 and potential use in increasing the production of tomato.
Preparative biochemistry & biotechnology.
2024 May; 54(5):637-646. doi:
10.1080/10826068.2023.2261058. [PMID: 37768129] - Zhen Guo, Jian Wang, Tianqing Chen, Haiou Zhang, Xiandong Hou, Juan Li. Effects of γ-polyglutamic acid supplementation on alfalfa growth and rhizosphere soil microorganisms in sandy soil.
Scientific reports.
2024 03; 14(1):6440. doi:
10.1038/s41598-024-57197-6. [PMID: 38499631] - Hongqian Zhang, Xue Gao, Qian Sun, Xiaoxue Dong, Zongwei Zhu, Chuanxu Yang. Incorporation of poly(γ-glutamic acid) in lipid nanoparticles for enhanced mRNA delivery efficiency in vitro and in vivo.
Acta biomaterialia.
2024 Mar; 177(?):361-376. doi:
10.1016/j.actbio.2024.02.004. [PMID: 38342193] - Ying Li, Weijie Zhang, Chao Tang, Chen Wang, Changhui Liu, Qian Chen, Kai Yang, Yian Gu, Peng Lei, Hong Xu, Rui Wang. Antidiabetic effects and mechanism of γ-polyglutamic acid on type II diabetes mice.
International journal of biological macromolecules.
2024 Mar; 261(Pt 1):129809. doi:
10.1016/j.ijbiomac.2024.129809. [PMID: 38290633] - Tomasz Skalski, Ewelina Zając, Elżbieta Jędrszczyk, Katarzyna Papaj, Joanna Kohyt, Artur Góra, Anna Kasprzycka, Divine Shytum, Barbara Skowera, Agnieszka Ziernicka-Wojtaszek. Effects of γ-polyglutamic acid on grassland sandy soil properties and plant functional traits exposed to drought stress.
Scientific reports.
2024 02; 14(1):3769. doi:
10.1038/s41598-024-54459-1. [PMID: 38355917] - Delin Yan, Lei Huang, Zhiqing Mei, Han Bao, Yaman Xie, Cunyi Yang, Xiangyang Gao. Untargeted metabolomics revealed the effect of soybean metabolites on poly(γ-glutamic acid) production in fermented natto and its metabolic pathway.
Journal of the science of food and agriculture.
2024 Feb; 104(3):1298-1307. doi:
10.1002/jsfa.13011. [PMID: 37782527] - Fengqing Wang, Yanmei Chen, Jia Zheng, Can Yang, Li Li, Rong Li, Meilin Shi, Zhongxuan Li. Preparation of potential organic fertilizer rich in γ-polyglutamic acid via microbial fermentation using brewer's spent grain as basic substrate.
Bioresource technology.
2024 Feb; 394(?):130216. doi:
10.1016/j.biortech.2023.130216. [PMID: 38122994] - Bei Zhang, Lei Qi, Xinhua Xie, Yue Shen, Jiahui Li, Bobo Zhang, Hongshuai Zhu. Emulsifying properties of O/W emulsion stabilized by soy protein isolate and γ-polyglutamic acid electrostatic complex.
Journal of food science.
2024 Jan; 89(1):174-185. doi:
10.1111/1750-3841.16873. [PMID: 38051023] - Fei Kang, Qilin Lv, Jingbiao Fan, Yun Zhang, Yuling Song, Xueqin Ren, Shuwen Hu. Ameliorative effect of calcium poly(aspartic acid) (PASP-Ca) and calcium poly-γ-glutamic acid (γ-PGA-Ca) on soil acidity in different horizons.
Environmental science and pollution research international.
2023 Jun; 30(30):75681-75693. doi:
10.1007/s11356-023-27713-8. [PMID: 37222895] - Qili Wang, Shunping Han, Yongqin Zhu, Guowei Wang, Danfei Chen. Poly-γ-glutamic acid coating polymeric nanoparticles enhance renal drug distribution and cellular uptake for diabetic nephropathy therapy.
Journal of drug targeting.
2023 01; 31(1):89-99. doi:
10.1080/1061186x.2022.2106488. [PMID: 35880399] - Jin Quan, Weiwei Zheng, Jingru Tan, Zewei Li, Meifang Wu, Seung-Beom Hong, Yanting Zhao, Zhujun Zhu, Yunxiang Zang. Glutamic Acid and Poly-γ-glutamic Acid Enhanced the Heat Resistance of Chinese Cabbage (Brassica rapa L. ssp. pekinensis) by Improving Carotenoid Biosynthesis, Photosynthesis, and ROS Signaling.
International journal of molecular sciences.
2022 Oct; 23(19):. doi:
10.3390/ijms231911671. [PMID: 36232971] - Qingjing Niu, Shuhui Gao, Xingwen Liu, Jinghui Chong, Lixia Ren, Kongying Zhu, Wenxiong Shi, Xiaoyan Yuan. Membrane stabilization versus perturbation by aromatic monoamine-modified γ-PGA for cryopreservation of human RBCs with high intracellular trehalose.
Journal of materials chemistry. B.
2022 08; 10(31):6038-6048. doi:
10.1039/d2tb01074g. [PMID: 35894777] - Naling Bai, Yu He, Hanlin Zhang, Xianqing Zheng, Rong Zeng, Yi Li, Shuangxi Li, Weiguang Lv. γ-Polyglutamic Acid Production, Biocontrol, and Stress Tolerance: Multifunction of Bacillus subtilis A-5 and the Complete Genome Analysis.
International journal of environmental research and public health.
2022 06; 19(13):. doi:
10.3390/ijerph19137630. [PMID: 35805288] - Hongbing Liu, Xiaowen Li, Muse Ji, Na Wang, Ying Xu, Yihan Kong, Jingxin Gou, Tian Yin, Haibing He, Yu Zhang, Xing Tang. Two-step fabricating micelle-like nanoparticles of cisplatin with the 'real' long circulation and high bioavailability for cancer therapy.
Colloids and surfaces. B, Biointerfaces.
2022 Feb; 210(?):112225. doi:
10.1016/j.colsurfb.2021.112225. [PMID: 34861539] - Shuxuan Wang, Yao Chen, Houshun Fang, Yan Xu, Ming Ding, Chunshuang Ma, Yanyan Lin, Zhiyan Cui, Huiying Sun, Qun Niu, Shuzhang Sun, Bin-Bing S Zhou, Ning Xiao, Hui Li. A γ-glutamyl hydrolase lacking the signal peptide confers susceptibility to folates/antifolates in acute lymphoblastic leukemia cells.
FEBS letters.
2022 02; 596(4):437-448. doi:
10.1002/1873-3468.14285. [PMID: 35040120] - Haizhen Ma, Panpan Li, Xingwang Liu, Can Li, Shengkui Zhang, Xiaohan Wang, Xia Tao. Poly-γ-glutamic acid enhanced the drought resistance of maize by improving photosynthesis and affecting the rhizosphere microbial community.
BMC plant biology.
2022 Jan; 22(1):11. doi:
10.1186/s12870-021-03392-w. [PMID: 34979944] - Eva Musdalita, Rudy Hidayat, Sumariyono Sumariyono, Suryo Anggoro Kusumo Wibowo, Anna Ariane, Hamzah Shatri, Iris Rengganis, Dono Antono. Correlation between serum methotrexate-polyglutamate 3 (MTX-PG3) level and disease activity in rheumatoid arthritis patients: A prospective cohort study.
F1000Research.
2022; 11(?):187. doi:
10.12688/f1000research.108714.1. [PMID: 35284067] - Ivana Rajšić, Slavica Lazarević, Maja Đanić, Hani Al-Salami, Armin Mooranian, Saša Vukmirović, Momir Mikov, Svetlana Goločorbin-Kon. Plasma Distribution of Methotrexate and Its Polyglutamates in Pediatric Acute Lymphoblastic Leukemia: Preliminary Insights.
European journal of drug metabolism and pharmacokinetics.
2022 Jan; 47(1):127-134. doi:
10.1007/s13318-021-00726-9. [PMID: 34637107] - Yue Mu, Dong Tang, Liang Mao, Dan Zhang, Pei Zhou, Yuee Zhi, Jinzhong Zhang. Phytoremediation of secondary saline soil by halophytes with the enhancement of γ-polyglutamic acid.
Chemosphere.
2021 Dec; 285(?):131450. doi:
10.1016/j.chemosphere.2021.131450. [PMID: 34246095] - Tomoaki Kurosaki, Yuki Katafuchi, Junya Hashizume, Hitomi Harasawa, Hiroo Nakagawa, Mikiro Nakashima, Tadahiro Nakamura, Chikamasa Yamashita, Hitoshi Sasaki, Yukinobu Kodama. Induction of mucosal immunity by pulmonary administration of a cell-targeting nanoparticle.
Drug delivery.
2021 Dec; 28(1):1585-1593. doi:
10.1080/10717544.2021.1955040. [PMID: 34291725] - Chongyang Zhu, Ning Tang, Jing Gan, Xiaojun Zhang, Yang Li, Xin Jia, Yongqiang Cheng. A pH-sensitive semi-interpenetrating polymer network hydrogels constructed by konjac glucomannan and poly (γ-glutamic acid): Synthesis, characterization and swelling behavior.
International journal of biological macromolecules.
2021 Aug; 185(?):229-239. doi:
10.1016/j.ijbiomac.2021.06.046. [PMID: 34119552] - Kai Yang, Qian Wang, Yu Wang, Sha Li, Yian Gu, Nan Gao, Fuhai Zhang, Peng Lei, Rui Wang, Hong Xu. Poly(γ-glutamic acid) Nanocoating To Enhance the Viability of Pseudomonas stutzeri NRCB010 through Cell Surface Engineering.
ACS applied materials & interfaces.
2021 Aug; 13(33):39957-39966. doi:
10.1021/acsami.1c12538. [PMID: 34376049] - Yu-Hsiu Chiu, Yan-Wei Wu, Jui-I Hung, Mei-Chin Chen. Epigallocatechin gallate/L-ascorbic acid-loaded poly-γ-glutamate microneedles with antioxidant, anti-inflammatory, and immunomodulatory effects for the treatment of atopic dermatitis.
Acta biomaterialia.
2021 08; 130(?):223-233. doi:
10.1016/j.actbio.2021.05.032. [PMID: 34087444] - Shulong Wu, Liqian Mo, Chunxiao Ye, Tianrong Xun, Xiaokang Wang, Bin Lv, Xia Zhan, Bin Liu, Qing Ding, Jun Peng, Congyan Chen, Xixiao Yang. Effect of total glucosides of paeony and Tripterygium wilfordii polyglycosides on erythrocyte methotrexate polyglutamates in rats, analysed using ultra-high-performance liquid chromatography-tandem mass spectrometry.
The Journal of pharmacy and pharmacology.
2021 Jul; 73(8):1039-1048. doi:
10.1093/jpp/rgab025. [PMID: 33749788] - Meng Wei, Yu-I Hsu, Taka-Aki Asoh, Moon-Hee Sung, Hiroshi Uyama. Injectable poly(γ-glutamic acid)-based biodegradable hydrogels with tunable gelation rate and mechanical strength.
Journal of materials chemistry. B.
2021 04; 9(16):3584-3594. doi:
10.1039/d1tb00412c. [PMID: 33909743] - Laith Z Samarah, Tina H Tran, Gary Stacey, Akos Vertes. Mass Spectrometry Imaging of Bio-oligomer Polydispersity in Plant Tissues by Laser Desorption Ionization from Silicon Nanopost Arrays.
Angewandte Chemie (International ed. in English).
2021 04; 60(16):9071-9077. doi:
10.1002/anie.202015251. [PMID: 33529427] - Duck Hyun Kim, Yeong Suk Yoo, Hee Jin Yoo, Yoon Ji Choi, Soon Ae Kim, Dong-Hyuk Sheen, Sang Kwang Lee, Mi Kyoung Lim, Kun Cho. Analysis of hair and plasma samples for methotrexate (MTX) and metabolite using high-performance liquid chromatography triple quadrupole mass spectrometry (LC-MS/MS) detection.
Journal of mass spectrometry : JMS.
2021 Apr; 56(4):e4648. doi:
10.1002/jms.4648. [PMID: 32954603] - Zhonghua Ouyang, Jing Huang, Yi Ren, Huanhuan Li, Yao Ding, Ke Zhang, Lei Jiang, Peng Yu. Studies on the intracellular accumulation process of methotrexate and its correlation with the key protein using an LC-MS/MS method: a novel way to realize prospective individualized medication.
Analytical and bioanalytical chemistry.
2021 Mar; 413(7):1799-1807. doi:
10.1007/s00216-020-03125-2. [PMID: 33564926] - Dorien Van Lysebetten, Alessio Malfanti, Kim Deswarte, Kaloian Koynov, Bianka Golba, Tingting Ye, Zifu Zhong, Sabah Kasmi, Alexander Lamoot, Yong Chen, Simon Van Herck, Bart N Lambrecht, Niek N Sanders, Stefan Lienenklaus, Sunil A David, María J Vicent, Stefaan De Koker, Bruno G De Geest. Lipid-Polyglutamate Nanoparticle Vaccine Platform.
ACS applied materials & interfaces.
2021 Feb; 13(5):6011-6022. doi:
10.1021/acsami.0c20607. [PMID: 33507728] - Ji-Hui Ha, Young-Jin Kim. Photodynamic and Cold Atmospheric Plasma Combination Therapy Using Polymeric Nanoparticles for the Synergistic Treatment of Cervical Cancer.
International journal of molecular sciences.
2021 Jan; 22(3):. doi:
10.3390/ijms22031172. [PMID: 33504007] - Lili Zhao, Jieru Yang, Ummey Jannatun Nahar, Zeinab G Khalil, Robert J Capon, Waleed M Hussein, Mariusz Skwarczynski, Istvan Toth. A dual-adjuvanting strategy for peptide-based subunit vaccines against group A Streptococcus: Lipidation and polyelectrolyte complexes.
Bioorganic & medicinal chemistry.
2020 12; 28(24):115823. doi:
10.1016/j.bmc.2020.115823. [PMID: 33120079] - Giovanni Paganelli, Anna Sarnelli, Stefano Severi, Maddalena Sansovini, Maria Luisa Belli, Manuela Monti, Flavia Foca, Monica Celli, Silvia Nicolini, Elisa Tardelli, Irene Marini, Federica Matteucci, Melchiore Giganti, Valentina Di Iorio, Ugo De Giorgi. Dosimetry and safety of 177Lu PSMA-617 along with polyglutamate parotid gland protector: preliminary results in metastatic castration-resistant prostate cancer patients.
European journal of nuclear medicine and molecular imaging.
2020 12; 47(13):3008-3017. doi:
10.1007/s00259-020-04856-1. [PMID: 32430583] - Xiaohan Wang, Geyu Dong, Xingwang Liu, Shengkui Zhang, Can Li, Xianqin Lu, Tao Xia. Poly-γ-glutamic acid-producing bacteria reduced Cd uptake and effected the rhizosphere microbial communities of lettuce.
Journal of hazardous materials.
2020 Nov; 398(?):123146. doi:
10.1016/j.jhazmat.2020.123146. [PMID: 32768845] - Jorge L Muriel Mundo, Hualu Zhou, Yunbing Tan, Jinning Liu, David Julian McClements. Stabilization of soybean oil-in-water emulsions using polypeptide multilayers: Cationic polylysine and anionic polyglutamic acid.
Food research international (Ottawa, Ont.).
2020 11; 137(?):109304. doi:
10.1016/j.foodres.2020.109304. [PMID: 33233043] - Florence Hermal, Benoît Frisch, Alexandre Specht, Line Bourel-Bonnet, Béatrice Heurtault. Development and characterization of layer-by-layer coated liposomes with poly(L-lysine) and poly(L-glutamic acid) to increase their resistance in biological media.
International journal of pharmaceutics.
2020 Aug; 586(?):119568. doi:
10.1016/j.ijpharm.2020.119568. [PMID: 32592900] - Jie Yu, Ni Wu, Xiaohui Zheng, Maosheng Zheng. Preparation of water-soluble chitosan/poly-gama-glutamic acid-tanshinone IIA encapsulation composite and its in vitro/in vivo drug release properties.
Biomedical physics & engineering express.
2020 06; 6(4):045020. doi:
10.1088/2057-1976/ab9ab2. [PMID: 33444280] - Jong Min Lee, Won Je Jang, So Hee Park, In-Soo Kong. Antioxidant and gastrointestinal cytoprotective effect of edible polypeptide poly-γ-glutamic acid.
International journal of biological macromolecules.
2020 Jun; 153(?):616-624. doi:
10.1016/j.ijbiomac.2020.03.050. [PMID: 32165198] - V Maksimovic, Z Pavlovic-Popovic, S Vukmirovic, J Cvejic, A Mooranian, H Al-Salami, M Mikov, S Golocorbin-Kon. Molecular mechanism of action and pharmacokinetic properties of methotrexate.
Molecular biology reports.
2020 Jun; 47(6):4699-4708. doi:
10.1007/s11033-020-05481-9. [PMID: 32415503] - Yao Ding, Yansha Hao, Zhang Yuan, Bailong Tao, Maowen Chen, Chuanchuan Lin, Peng Liu, Kaiyong Cai. A dual-functional implant with an enzyme-responsive effect for bacterial infection therapy and tissue regeneration.
Biomaterials science.
2020 Mar; 8(7):1840-1854. doi:
10.1039/c9bm01924c. [PMID: 31967110] - Dongyoon Kim, Junho Byun, Jinwon Park, Yeon Lee, Gayong Shim, Yu-Kyoung Oh. Biomimetic polymeric nanoparticle-based photodynamic immunotherapy and protection against tumor rechallenge.
Biomaterials science.
2020 Feb; 8(4):1106-1116. doi:
10.1039/c9bm01704f. [PMID: 31994549] - Gina Córdoba-David, Aroa Duro-Castano, Regiane Cardoso Castelo-Branco, Cristian González-Guerrero, Pablo Cannata, Ana B Sanz, María J Vicent, Alberto Ortiz, Adrián M Ramos. Effective Nephroprotection Against Acute Kidney Injury with a Star-Shaped Polyglutamate-Curcuminoid Conjugate.
Scientific reports.
2020 02; 10(1):2056. doi:
10.1038/s41598-020-58974-9. [PMID: 32029842] - Zongqi Xu, Junjie Ma, Peng Lei, Qian Wang, Xiaohai Feng, Hong Xu. Poly-γ-glutamic acid induces system tolerance to drought stress by promoting abscisic acid accumulation in Brassica napus L.
Scientific reports.
2020 01; 10(1):252. doi:
10.1038/s41598-019-57190-4. [PMID: 31937837] - Shikhar Sharma, Rakesh Bhatnagar, Deepak Gaur. Bacillus anthracis Poly-γ-D-Glutamate Capsule Inhibits Opsonic Phagocytosis by Impeding Complement Activation.
Frontiers in immunology.
2020; 11(?):462. doi:
10.3389/fimmu.2020.00462. [PMID: 32296419] - Kang Jiang, Bao Tang, Qian Wang, Zongqi Xu, Liang Sun, Junjie Ma, Sha Li, Hong Xu, Peng Lei. The bio-processing of soybean dregs by solid state fermentation using a poly γ-glutamic acid producing strain and its effect as feed additive.
Bioresource technology.
2019 Nov; 291(?):121841. doi:
10.1016/j.biortech.2019.121841. [PMID: 31349173] - Yuri Ikeuchi-Takahashi, Yudai Shiokawa, Kazuki Sekita, Etsuo Yonemochi, Hiraku Onishi. Development of microparticles coated with poly-γ-glutamic acid to improve oral absorption of a poorly water-soluble drug.
Pharmaceutical development and technology.
2019 Oct; 24(8):992-1001. doi:
10.1080/10837450.2019.1621898. [PMID: 31107609] - Yibin Qiu, Yatao Zhang, Yifan Zhu, Yuanyuan Sha, Zongqi Xu, Xiaohai Feng, Sha Li, Hong Xu. Improving poly-(γ-glutamic acid) production from a glutamic acid-independent strain from inulin substrate by consolidated bioprocessing.
Bioprocess and biosystems engineering.
2019 Oct; 42(10):1711-1720. doi:
10.1007/s00449-019-02167-w. [PMID: 31286217] - Chenglong Chen, Xuchu Lv, Wu Lei, Yi Wu, Shasha Feng, Yong Ding, Jingjing Lv, Qingli Hao, Shen-Ming Chen. Amoxicillin on polyglutamic acid composite three-dimensional graphene modified electrode: Reaction mechanism of amoxicillin insights by computational simulations.
Analytica chimica acta.
2019 Sep; 1073(?):22-29. doi:
10.1016/j.aca.2019.04.052. [PMID: 31146832] - Wai-Ching Liu, Huey-Yuan Wang, Tsung-Han Lee, Ren-Jei Chung. Gamma-poly glutamate/gelatin composite hydrogels crosslinked by proanthocyanidins for wound healing.
Materials science & engineering. C, Materials for biological applications.
2019 Aug; 101(?):630-639. doi:
10.1016/j.msec.2019.04.018. [PMID: 31029356] - Hye-Ji Lee, Ha-Kyoung Kwon, Hye Su Kim, Moon Il Kim, Hye-Jin Park. Hair Growth Promoting Effect of 4HGF Encapsulated with PGA Nanoparticles (PGA-4HGF) by β-Catenin Activation and Its Related Cell Cycle Molecules.
International journal of molecular sciences.
2019 Jul; 20(14):. doi:
10.3390/ijms20143447. [PMID: 31337050] - C B Kolton, C K Marston, R A Stoddard, C Cossaboom, J S Salzer, T R Kozel, M A Gates-Hollingsworth, C A Cleveland, A T Thompson, M F Dalton, M J Yabsley, A R Hoffmaster. Detection of Bacillus anthracis in animal tissues using InBios active anthrax detect rapid test lateral flow immunoassay.
Letters in applied microbiology.
2019 Jun; 68(6):480-484. doi:
10.1111/lam.13134. [PMID: 30776143] - Yu-Wen Lo, Ming-Thau Sheu, Wen-Hsuan Chiang, Ya-Ling Chiu, Chia-Mu Tu, Wen-Yu Wang, Ming-Hsi Wu, Yu-Cheng Wang, Maggie Lu, Hsiu-O Ho. In situ chemically crosslinked injectable hydrogels for the subcutaneous delivery of trastuzumab to treat breast cancer.
Acta biomaterialia.
2019 03; 86(?):280-290. doi:
10.1016/j.actbio.2019.01.003. [PMID: 30616077] - Dileep Urimi, Ashish Kumar Agrawal, Varun Kushwah, Sanyog Jain. Polyglutamic Acid Functionalization of Chitosan Nanoparticles Enhances the Therapeutic Efficacy of Insulin Following Oral Administration.
AAPS PharmSciTech.
2019 Feb; 20(3):131. doi:
10.1208/s12249-019-1330-2. [PMID: 30815757] - Weifeng Lin, Guanglong Ma, Zhefan Yuan, Haofeng Qian, Liangbo Xu, Elie Sidransky, Shengfu Chen. Development of Zwitterionic Polypeptide Nanoformulation with High Doxorubicin Loading Content for Targeted Drug Delivery.
Langmuir : the ACS journal of surfaces and colloids.
2019 02; 35(5):1273-1283. doi:
10.1021/acs.langmuir.8b00851. [PMID: 29933695] - Hye Su Kim, Ha-Kyoung Kwon, Dong Hoon Lee, Thao Nguyen Le, Hye-Jin Park, Moon Il Kim. Poly(γ-Glutamic Acid)/Chitosan Hydrogel Nanoparticles For Effective Preservation And Delivery Of Fermented Herbal Extract For Enlarging Hair Bulb And Enhancing Hair Growth.
International journal of nanomedicine.
2019; 14(?):8409-8419. doi:
10.2147/ijn.s227514. [PMID: 31695374] - Jacob Nersting, Stine Nygaard Nielsen, Kathrine Grell, Maria Paerregaard, Jonas Abrahamsson, Bendik Lund, Olafur Gisli Jonsson, Kaie Pruunsild, Goda Vaitkeviciene, Jukka Kanerva, Kjeld Schmiegelow. Methotrexate polyglutamate levels and co-distributions in childhood acute lymphoblastic leukemia maintenance therapy.
Cancer chemotherapy and pharmacology.
2019 01; 83(1):53-60. doi:
10.1007/s00280-018-3704-7. [PMID: 30324220] - Xuebin Ma, Shuai Liu, Hejun Tang, Rong Yang, Bo Chi, Zhiwen Ye. In situ photocrosslinked hyaluronic acid and poly (γ-glutamic acid) hydrogels as injectable drug carriers for load-bearing tissue application.
Journal of biomaterials science. Polymer edition.
2018 12; 29(18):2252-2266. doi:
10.1080/09205063.2018.1535820. [PMID: 30311855] - Zahra Salmasi, Ahad Mokhtarzadeh, Maryam Hashemi, Mahboubeh Ebrahimian, Sara Amel Farzad, Hamideh Parhiz, Mohammad Ramezani. Effective and safe in vivo gene delivery based on polyglutamic acid complexes with heterocyclic amine modified-polyethylenimine.
Colloids and surfaces. B, Biointerfaces.
2018 Dec; 172(?):790-796. doi:
10.1016/j.colsurfb.2018.09.028. [PMID: 30268055] - Zhaopei Guo, Lin Lin, Jie Chen, Xingzhi Zhou, Hon Fai Chan, Xuesi Chen, Huayu Tian, Meiwan Chen. Poly(ethylene glycol)-poly-l-glutamate complexed with polyethyleneimine-polyglycine for highly efficient gene delivery in vitro and in vivo.
Biomaterials science.
2018 Nov; 6(11):3053-3062. doi:
10.1039/c8bm00503f. [PMID: 30288524] - Chenguang Yang, Wantong Song, Dawei Zhang, Haiyang Yu, Lei Yin, Na Shen, Mingxiao Deng, Zhaohui Tang, Jingkai Gu, Xuesi Chen. Poly (l-glutamic acid)-g-methoxy poly (ethylene glycol)-gemcitabine conjugate improves the anticancer efficacy of gemcitabine.
International journal of pharmaceutics.
2018 Oct; 550(1-2):79-88. doi:
10.1016/j.ijpharm.2018.08.037. [PMID: 30138704] - Wei Chu, Pengqian Tian, Ning Ding, Qing Cai, Jinlong Li, Xuezhi Zhuo, Zhaohui Tang, Jingxin Gou, Tian Yin, Yu Zhang, Haibing He, Xing Tang. Improving Plasma Stability and Bioavailability In Vivo of Gemcitabine Via Nanoparticles of mPEG-PLG-GEM Complexed with Calcium Phosphate.
Pharmaceutical research.
2018 Oct; 35(12):230. doi:
10.1007/s11095-018-2506-2. [PMID: 30327887] - Christina Apfelthaler, Katharina Skoll, Raphaela Ciola, Franz Gabor, Michael Wirth. A doxorubicin loaded colloidal delivery system for the intravesical therapy of non-muscle invasive bladder cancer using wheat germ agglutinin as targeter.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2018 Sep; 130(?):177-184. doi:
10.1016/j.ejpb.2018.06.028. [PMID: 29960015] - Kai He, Xiaoyu Ma, Tao Xu, Yan Li, Allen Hodge, Qing Zhang, Julia Torline, Yan Huang, Jian Zhao, Kun Ling, Jinghua Hu. Axoneme polyglutamylation regulated by Joubert syndrome protein ARL13B controls ciliary targeting of signaling molecules.
Nature communications.
2018 08; 9(1):3310. doi:
10.1038/s41467-018-05867-1. [PMID: 30120249] - Kgaugelo Edward Lekota, Oliver Keoagile Ignatius Bezuidt, Joseph Mafofo, Jasper Rees, Farai Catherine Muchadeyi, Evelyn Madoroba, Henriette van Heerden. Whole genome sequencing and identification of Bacillus endophyticus and B. anthracis isolated from anthrax outbreaks in South Africa.
BMC microbiology.
2018 07; 18(1):67. doi:
10.1186/s12866-018-1205-9. [PMID: 29986655] - Hoay Yan Cheah, Elena Gallon, Fabienne Dumoulin, See Ziau Hoe, Nina Japundžić-Žigon, Sofija Glumac, Hong Boon Lee, Prem Anand, Lip Yong Chung, Maria Jesus Vicent, Lik Voon Kiew. Near-Infrared Activatable Phthalocyanine-Poly-L-Glutamic Acid Conjugate: Enhanced in Vivo Safety and Antitumor Efficacy toward an Effective Photodynamic Cancer Therapy.
Molecular pharmaceutics.
2018 07; 15(7):2594-2605. doi:
10.1021/acs.molpharmaceut.8b00132. [PMID: 29763568] - Yiyang Yu, Fang Yan, Yinghao He, Yuxuan Qin, Yun Chen, Yunrong Chai, Jian-Hua Guo. The ClpY-ClpQ protease regulates multicellular development in Bacillus subtilis.
Microbiology (Reading, England).
2018 05; 164(5):848-862. doi:
10.1099/mic.0.000658. [PMID: 29629859] - Jong Min Lee, Jang-Ho Kim, Kang Woong Kim, Bong-Joo Lee, Dong-Gyun Kim, Young-Ok Kim, Jong-Hee Lee, In-Soo Kong. Physicochemical properties, production, and biological functionality of poly-γ-d-glutamic acid with constant molecular weight from halotolerant Bacillus sp. SJ-10.
International journal of biological macromolecules.
2018 Mar; 108(?):598-607. doi:
10.1016/j.ijbiomac.2017.12.055. [PMID: 29229248] - Md Hasan Turabee, Thavasyappan Thambi, Huu Thuy Trang Duong, Ji Hoon Jeong, Doo Sung Lee. A pH- and temperature-responsive bioresorbable injectable hydrogel based on polypeptide block copolymers for the sustained delivery of proteins in vivo.
Biomaterials science.
2018 Feb; 6(3):661-671. doi:
10.1039/c7bm00980a. [PMID: 29423489] - Giulia Morgese, Emma Cavalli, Jan-Georg Rosenboom, Marcy Zenobi-Wong, Edmondo M Benetti. Cyclic Polymer Grafts That Lubricate and Protect Damaged Cartilage.
Angewandte Chemie (International ed. in English).
2018 02; 57(6):1621-1626. doi:
10.1002/anie.201712534. [PMID: 29283471] - Marcel P Stoop, Sabine Visser, Evert van Dijk, Joachim G J V Aerts, Bruno H Stricker, Theo M Luider. High and individually variable enzymatic activity precludes accurate determination of pemetrexed, methotrexate and their polyglutamate metabolite concentrations in plasma.
Journal of pharmaceutical and biomedical analysis.
2018 Jan; 148(?):89-92. doi:
10.1016/j.jpba.2017.09.014. [PMID: 28965049] - Xuebin Ma, Tingting Xu, Wei Chen, Hongye Qin, Bo Chi, Zhiwen Ye. Injectable hydrogels based on the hyaluronic acid and poly (γ-glutamic acid) for controlled protein delivery.
Carbohydrate polymers.
2018 Jan; 179(?):100-109. doi:
10.1016/j.carbpol.2017.09.071. [PMID: 29111032] - Li Zhang, Junli Chang, Yongjian Zhao, Hao Xu, Tengteng Wang, Qiang Li, Lianping Xing, Jing Huang, Yongjun Wang, Qianqian Liang. Fabrication of a triptolide-loaded and poly-γ-glutamic acid-based amphiphilic nanoparticle for the treatment of rheumatoid arthritis.
International journal of nanomedicine.
2018; 13(?):2051-2064. doi:
10.2147/ijn.s151233. [PMID: 29670349] - Li Zhang, Xiaoyu Zhu, Shijia Wu, Yazhou Chen, Shiming Tan, Yingjie Liu, Wenzheng Jiang, Jing Huang. Fabrication and evaluation of a γ-PGA-based self-assembly transferrin receptor-targeting anticancer drug carrier.
International journal of nanomedicine.
2018; 13(?):7873-7889. doi:
10.2147/ijn.s181121. [PMID: 30538465] - Dexian Kong, Lili Jiang, Yijun Liu, Zeming Wang, Libin Han, Rixin Lv, Jiandi Lin, Chun-Hua Lu, Yuwu Chi, Guonan Chen. Electrochemical investigation and determination of procaterol hydrochloride on poly(glutamic acid)/carboxyl functionalized multiwalled carbon nanotubes/polyvinyl alcohol modified glassy carbon electrode.
Talanta.
2017 Nov; 174(?):436-443. doi:
10.1016/j.talanta.2017.06.047. [PMID: 28738604] - Syuan-Yian Mao, Tu-Fa Lien. Effects of nanosized zinc oxide and γ-polyglutamic acid on eggshell quality and serum parameters of aged laying hens.
Archives of animal nutrition.
2017 Oct; 71(5):373-383. doi:
10.1080/1745039x.2017.1355600. [PMID: 28771048] - Zongqi Xu, Peng Lei, Xiao Pang, Huashan Li, Xiaohai Feng, Hong Xu. Exogenous application of poly-γ-glutamic acid enhances stress defense in Brassica napus L. seedlings by inducing cross-talks between Ca2+, H2O2, brassinolide, and jasmonic acid in leaves.
Plant physiology and biochemistry : PPB.
2017 Sep; 118(?):460-470. doi:
10.1016/j.plaphy.2017.07.015. [PMID: 28743039] - Tereza Pereira de Souza, Guilherme Volpe Bossa, Pasquale Stano, Frank Steiniger, Sylvio May, Pier Luigi Luisi, Alfred Fahr. Vesicle aggregates as a model for primitive cellular assemblies.
Physical chemistry chemical physics : PCCP.
2017 Aug; 19(30):20082-20092. doi:
10.1039/c7cp03751a. [PMID: 28726904] - Gayong Shim, Dongyoon Kim, Jinyoung Kim, Min Sung Suh, Youn Kyu Kim, Yu-Kyoung Oh. Bacteriomimetic poly-γ-glutamic acid surface coating for hemocompatibility and safety of nanomaterials.
Nanotoxicology.
2017 Aug; 11(6):762-770. doi:
10.1080/17435390.2017.1353155. [PMID: 28685628] - Lei Zhang, Xueming Yang, Decai Gao, Lingli Wang, Jie Li, Zhanbo Wei, Yuanliang Shi. Effects of poly-γ-glutamic acid (γ-PGA) on plant growth and its distribution in a controlled plant-soil system.
Scientific reports.
2017 07; 7(1):6090. doi:
10.1038/s41598-017-06248-2. [PMID: 28729559] - Dina Polyak, Adva Krivitsky, Anna Scomparin, Shay Eliyahu, Hagar Kalinski, Sharon Avkin-Nachum, Ronit Satchi-Fainaro. Systemic delivery of siRNA by aminated poly(α)glutamate for the treatment of solid tumors.
Journal of controlled release : official journal of the Controlled Release Society.
2017 07; 257(?):132-143. doi:
10.1016/j.jconrel.2016.06.034. [PMID: 27356019] - Luyao Wang, Ning Wang, Dandan Mi, Yuming Luo, Jianhua Guo. Poly-γ-glutamic acid productivity of Bacillus subtilis BsE1 has positive function in motility and biocontrol against Fusarium graminearum.
Journal of microbiology (Seoul, Korea).
2017 Jul; 55(7):554-560. doi:
10.1007/s12275-017-6589-y. [PMID: 28664519] - Ji-Soo Lee, Da Young Hong, Eun Suh Kim, Hyeon Gyu Lee. Improving the water solubility and antimicrobial activity of silymarin by nanoencapsulation.
Colloids and surfaces. B, Biointerfaces.
2017 Jun; 154(?):171-177. doi:
10.1016/j.colsurfb.2017.03.004. [PMID: 28340483] - Andang Miatmoko, Kumi Kawano, Hitomi Yoda, Etsuo Yonemochi, Yoshiyuki Hattori. Tumor delivery of liposomal doxorubicin prepared with poly-L-glutamic acid as a drug-trapping agent.
Journal of liposome research.
2017 Jun; 27(2):99-107. doi:
10.3109/08982104.2016.1166511. [PMID: 26982164] - Lei Wang, Dongdong Kong, Qiang Lv, Guoqi Niu, Tingting Han, Xuanchao Zhao, Shulin Meng, Qian Cheng, Shouchun Guo, Jing Du, Zili Wu, Jinzheng Wang, Fang Bao, Yong Hu, Xiaojun Pan, Jinchan Xia, Dong Yuan, Lida Han, Tong Lian, Chunyi Zhang, Haiyang Wang, Xin-Jian He, Yi-Kun He. Tetrahydrofolate Modulates Floral Transition through Epigenetic Silencing.
Plant physiology.
2017 Jun; 174(2):1274-1284. doi:
10.1104/pp.16.01750. [PMID: 28450424] - Tianzhou Liu, Dawei Zhang, Wantong Song, Zhaohui Tang, Jiaming Zhu, Zhiming Ma, Xudong Wang, Xuesi Chen, Ti Tong. A poly(l-glutamic acid)-combretastatin A4 conjugate for solid tumor therapy: Markedly improved therapeutic efficiency through its low tissue penetration in solid tumor.
Acta biomaterialia.
2017 04; 53(?):179-189. doi:
10.1016/j.actbio.2017.02.001. [PMID: 28167300] - Alessandro Roncador, Elisa Oppici, Marina Talelli, Amaya Niño Pariente, Marta Donini, Stefano Dusi, Carla Borri Voltattorni, María J Vicent, Barbara Cellini. Use of polymer conjugates for the intraperoxisomal delivery of engineered human alanine:glyoxylate aminotransferase as a protein therapy for primary hyperoxaluria type I.
Nanomedicine : nanotechnology, biology, and medicine.
2017 04; 13(3):897-907. doi:
10.1016/j.nano.2016.12.011. [PMID: 27993722] - Toshihiko Doi, Tetsuya Hamaguchi, Kohei Shitara, Satoru Iwasa, Yasuhiro Shimada, Mitsunori Harada, Kenichiro Naito, Naoto Hayashi, Atsuhiro Masada, Atsushi Ohtsu. NC-6004 Phase I study in combination with gemcitabine for advanced solid tumors and population PK/PD analysis.
Cancer chemotherapy and pharmacology.
2017 03; 79(3):569-578. doi:
10.1007/s00280-017-3254-4. [PMID: 28224231] - Zhengfei Guo, Na Yang, Changhua Zhu, Lijun Gan. Exogenously applied poly-γ-glutamic acid alleviates salt stress in wheat seedlings by modulating ion balance and the antioxidant system.
Environmental science and pollution research international.
2017 Mar; 24(7):6592-6598. doi:
10.1007/s11356-016-8295-4. [PMID: 28078521] - Hee-Eun Jin, Jae-Chul Choi, Yong Taik Lim, Moon-Hee Sung. Prebiotic Effects of Poly-Gamma-Glutamate on Bacterial Flora in Murine Gut.
Journal of microbiology and biotechnology.
2017 Feb; 27(2):412-415. doi:
10.4014/jmb.1611.11023. [PMID: 27974732] - Peng Lei, Xiao Pang, Xiaohai Feng, Sha Li, Bo Chi, Rui Wang, Zongqi Xu, Hong Xu. The microbe-secreted isopeptide poly-γ-glutamic acid induces stress tolerance in Brassica napus L. seedlings by activating crosstalk between H2O2 and Ca2.
Scientific reports.
2017 02; 7(?):41618. doi:
10.1038/srep41618. [PMID: 28198821] - A E S Pereira, I E Sandoval-Herrera, S A Zavala-Betancourt, H C Oliveira, A S Ledezma-Pérez, J Romero, L F Fraceto. γ-Polyglutamic acid/chitosan nanoparticles for the plant growth regulator gibberellic acid: Characterization and evaluation of biological activity.
Carbohydrate polymers.
2017 Feb; 157(?):1862-1873. doi:
10.1016/j.carbpol.2016.11.073. [PMID: 27987906] - Sun-Hee Cho, Jung-Ran Noh, Mi Young Cho, Min-Jeong Go, Yong-Hoon Kim, Eun Sung Kang, Yong Ho Kim, Chul-Ho Lee, Yong Taik Lim. An injectable collagen/poly(γ-glutamic acid) hydrogel as a scaffold of stem cells and α-lipoic acid for enhanced protection against renal dysfunction.
Biomaterials science.
2017 Jan; 5(2):285-294. doi:
10.1039/c6bm00711b. [PMID: 27975097] - Nuno Martinho, Liana C Silva, Helena F Florindo, Steve Brocchini, Mire Zloh, Teresa S Barata. Rational design of novel, fluorescent, tagged glutamic acid dendrimers with different terminal groups and in silico analysis of their properties.
International journal of nanomedicine.
2017; 12(?):7053-7073. doi:
10.2147/ijn.s135475. [PMID: 29026301] - Yutong Wang, Liping Huang, Yan Shen, Lidan Tang, Runing Sun, Di Shi, Thomas J Webster, Jiasheng Tu, Chunmeng Sun. Electrostatic interactions between polyglutamic acid and polylysine yields stable polyion complex micelles for deoxypodophyllotoxin delivery.
International journal of nanomedicine.
2017; 12(?):7963-7977. doi:
10.2147/ijn.s140573. [PMID: 29133981] - Hann-Juang Chai, Lik-Voon Kiew, Yunni Chin, Anwar Norazit, Suzita Mohd Noor, Yoke-Lin Lo, Chung-Yeng Looi, Yeh-Siang Lau, Tuck-Meng Lim, Won-Fen Wong, Nor Azizan Abdullah, Munavvar Zubaid Abdul Sattar, Edward J Johns, Zamri Chik, Lip-Yong Chung. Renal targeting potential of a polymeric drug carrier, poly-l-glutamic acid, in normal and diabetic rats.
International journal of nanomedicine.
2017; 12(?):577-591. doi:
10.2147/ijn.s111284. [PMID: 28144140] - Hyun Jong Noh, Young-Woock Noh, Min Beom Heo, Eun-Ha Kim, Su-Jin Park, Young-Il Kim, Young Ki Choi, Yong Taik Lim. Injectable and Pathogen-Mimicking Hydrogels for Enhanced Protective Immunity against Emerging and Highly Pathogenic Influenza Virus.
Small (Weinheim an der Bergstrasse, Germany).
2016 Dec; 12(45):6279-6288. doi:
10.1002/smll.201602344. [PMID: 27671946] - Wei Zeng, Guiguang Chen, Hao Wu, Jun Wang, Yanliao Liu, Ye Guo, Zhiqun Liang. Improvement of Bacillus subtilis for poly-γ-glutamic acid production by genome shuffling.
Microbial biotechnology.
2016 11; 9(6):824-833. doi:
10.1111/1751-7915.12405. [PMID: 27562078] - Xiaochen Ma, Hongli Zheng, Wenguang Zhou, Yuhuan Liu, Paul Chen, Roger Ruan. Enhanced Harvesting of Chlorella vulgaris Using Combined Flocculants.
Applied biochemistry and biotechnology.
2016 Oct; 180(4):791-804. doi:
10.1007/s12010-016-2133-5. [PMID: 27206558] - Adva Krivitsky, Dina Polyak, Anna Scomparin, Shay Eliyahu, Asaf Ori, Sharon Avkin-Nachum, Vadim Krivitsky, Ronit Satchi-Fainaro. Structure-Function Correlation of Aminated Poly(α)glutamate as siRNA Nanocarriers.
Biomacromolecules.
2016 09; 17(9):2787-800. doi:
10.1021/acs.biomac.6b00555. [PMID: 27377188] - Marcel P Stoop, Sabine Visser, Evert van Dijk, Joachim G J V Aerts, Bruno H Stricker, Theo M Luider. A new quantification method for assessing plasma concentrations of pemetrexed and its polyglutamate metabolites.
Journal of pharmaceutical and biomedical analysis.
2016 Sep; 128(?):1-8. doi:
10.1016/j.jpba.2016.04.036. [PMID: 27209449]