[2-[Carboxymethyl-[2-[carboxymethyl-[2-[carboxymethyl-[2-(methylamino)-2-oxoniumylideneethyl]amino]ethyl]amino]ethyl]amino]-1-(methylamino)ethylidene]oxidanium;gadolinium(2+) (BioDeep_00000910875)
代谢物信息卡片
[2-[Carboxymethyl-[2-[carboxymethyl-[2-[carboxymethyl-[2-(methylamino)-2-oxoniumylideneethyl]amino]ethyl]amino]ethyl]amino]-1-(methylamino)ethylidene]oxidanium;gadolinium(2+)
化学式: C16H31GdN5O8+4 (579.1413636)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CNC(=[OH+])CN(CCN(CCN(CC(=[OH+])NC)CC(=O)O)CC(=O)O)CC(=O)O.[Gd+2]
InChI: /q
描述信息
V - Various > V08 - Contrast media > V08C - Magnetic resonance imaging contrast media > V08CA - Paramagnetic contrast media
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代谢反应
0 个相关的代谢反应过程信息。
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在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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文献列表
- Karolin Sommer, Sarah Reuter, Matthias Elinkmann, Alexander Köhrer, C Derrick Quarles, Michael Hippler, Uwe Karst. Species-dependent uptake of gadolinium in Chlamydomonas reinhardtii algae.
The Science of the total environment.
2023 Dec; 905(?):166909. doi:
10.1016/j.scitotenv.2023.166909. [PMID: 37689191] - Karolin Sommer, Tobias Becker, Maximilian von Bremen-Kühne, Mario Gotters, C Derrick Quarles, Michael Sperling, Jörg Kudla, Uwe Karst. Analysis of the elemental species-dependent uptake of lanthanide complexes in Arabidopsis thaliana plants by LA-ICP-MS.
Chemosphere.
2023 Oct; 338(?):139534. doi:
10.1016/j.chemosphere.2023.139534. [PMID: 37467858] - Yasukazu Takanezawa, Ryosuke Nakamura, Yuka Ohshiro, Shimpei Uraguchi, Masako Kiyono. Gadolinium-based contrast agents suppress adipocyte differentiation in 3T3-L1 cells.
Toxicology letters.
2023 Jul; 383(?):196-203. doi:
10.1016/j.toxlet.2023.07.003. [PMID: 37437671] - Izabela Strzeminska, Cecile Factor, Javier Jimenez-Lamana, Sabrina Lacomme, Maria Angels Subirana, Philippe Le Coustumer, Dirk Schaumlöffel, Philippe Robert, Joanna Szpunar, Claire Corot, Ryszard Lobinski. Comprehensive Speciation Analysis of Residual Gadolinium in Deep Cerebellar Nuclei in Rats Repeatedly Administered With Gadoterate Meglumine or Gadodiamide.
Investigative radiology.
2022 05; 57(5):283-292. doi:
10.1097/rli.0000000000000846. [PMID: 35066532] - Mostafa Alabousi, Matthew S Davenport. Use of Intravenous Gadolinium-based Contrast Media in Patients with Kidney Disease and the Risk of Nephrogenic Systemic Fibrosis: Radiology In Training.
Radiology.
2021 08; 300(2):279-284. doi:
10.1148/radiol.2021210044. [PMID: 34060939] - Julie Davies, Michael Marino, Adrian P L Smith, Janell M Crowder, Michael Larsen, Lisa Lowery, Jason Castle, Mark G Hibberd, Paul M Evans. Repeat and single dose administration of gadodiamide to rats to investigate concentration and location of gadolinium and the cell ultrastructure.
Scientific reports.
2021 07; 11(1):13950. doi:
10.1038/s41598-021-93147-2. [PMID: 34230532] - Safia M Alkhunizi, Marc Fakhoury, Wassim Abou-Kheir, Nada Lawand. Gadolinium Retention in the Central and Peripheral Nervous System: Implications for Pain, Cognition, and Neurogenesis.
Radiology.
2020 11; 297(2):407-416. doi:
10.1148/radiol.2020192645. [PMID: 32808889] - Hyewon Oh, Yong Eun Chung, Je Sung You, Chan Gyu Joo, Pan Ki Kim, Joon Seok Lim, Myeong-Jin Kim. Gadolinium retention in rat abdominal organs after administration of gadoxetic acid disodium compared to gadodiamide and gadobutrol.
Magnetic resonance in medicine.
2020 10; 84(4):2124-2132. doi:
10.1002/mrm.28249. [PMID: 32162406] - Izabela Strzeminska, Cécile Factor, Philippe Robert, Anne-Laure Grindel, Pierre-Olivier Comby, Joanna Szpunar, Claire Corot, Ryszard Lobinski. Long-Term Evaluation of Gadolinium Retention in Rat Brain After Single Injection of a Clinically Relevant Dose of Gadolinium-Based Contrast Agents.
Investigative radiology.
2020 03; 55(3):138-143. doi:
10.1097/rli.0000000000000623. [PMID: 31917763] - Enza Di Gregorio, Chiara Furlan, Sandra Atlante, Rachele Stefania, Eliana Gianolio, Silvio Aime. Gadolinium Retention in Erythrocytes and Leukocytes From Human and Murine Blood Upon Treatment With Gadolinium-Based Contrast Agents for Magnetic Resonance Imaging.
Investigative radiology.
2020 01; 55(1):30-37. doi:
10.1097/rli.0000000000000608. [PMID: 31503081] - Alexander Radbruch, Henning Richter, Stefanie Fingerhut, Louise Francoise Martin, Anna Xia, Niklas Henze, Werner Paulus, Michael Sperling, Uwe Karst, Astrid Jeibmann. Gadolinium Deposition in the Brain in a Large Animal Model: Comparison of Linear and Macrocyclic Gadolinium-Based Contrast Agents.
Investigative radiology.
2019 09; 54(9):531-536. doi:
10.1097/rli.0000000000000575. [PMID: 31261291] - Gregor Jost, Thomas Frenzel, Janina Boyken, Laura Schoeckel, Hubertus Pietsch. Gadolinium Presence in the Brain After Administration of the Liver-Specific Gadolinium-Based Contrast Agent Gadoxetate: A Systematic Comparison to Multipurpose Agents in Rats.
Investigative radiology.
2019 08; 54(8):468-474. doi:
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Radiology.
2019 08; 292(2):376-386. doi:
10.1148/radiol.2019182916. [PMID: 31264946] - Achmad Adhipatria Perayabangsa Kartamihardja, Hirofumi Hanaoka, Putri Andriana, Satomi Kameo, Ayako Takahashi, Hiroshi Koyama, Yoshito Tsushima. Quantitative analysis of Gd in the protein content of the brain following single injection of gadolinium-based contrast agents (GBCAs) by size exclusion chromatography.
The British journal of radiology.
2019 Jul; 92(1099):20190062. doi:
10.1259/bjr.20190062. [PMID: 31045442] - Türker Acar, Egemen Kaya, Mustafa Deniz Yoruk, Neslihan Duzenli, Recep Selim Senturk, Cenk Can, Lokman Ozturk, Canberk Tomruk, Yigit Uyanikgil, Frank J Rybicki. Changes in tissue gadolinium biodistribution measured in an animal model exposed to four chelating agents.
Japanese journal of radiology.
2019 Jun; 37(6):458-465. doi:
10.1007/s11604-019-00835-1. [PMID: 30929137] - Ningning Di, Wenna Cheng, Xingyue Jiang, Xinjiang Liu, Jinliang Zhou, Qian Xie, Zhihui Chu, Huacheng Chen, Bin Wang. Can dynamic contrast-enhanced MRI evaluate VEGF expression in brain glioma? An MRI-guided stereotactic biopsy study.
Journal of neuroradiology = Journal de neuroradiologie.
2019 May; 46(3):186-192. doi:
10.1016/j.neurad.2018.04.008. [PMID: 29752976] - Wendell Gibby, Wes Parish, Ray M Merrill, Diego Fernandez, Christopher R Anderson, Eric Merchel, Ryan Parr. The use of a binary chelate formulation: Could gadolinium based linear contrast agents be rescued by the addition of zinc selective chelates?.
Magnetic resonance imaging.
2019 05; 58(?):76-81. doi:
10.1016/j.mri.2019.01.001. [PMID: 30639754] - Aida Kiviniemi, Maria Gardberg, Paul Ek, Janek Frantzén, Johan Bobacka, Heikki Minn. Gadolinium retention in gliomas and adjacent normal brain tissue: association with tumor contrast enhancement and linear/macrocyclic agents.
Neuroradiology.
2019 May; 61(5):535-544. doi:
10.1007/s00234-019-02172-6. [PMID: 30710184] - Lara Chehabeddine, Tala Al Saleh, Marwa Baalbaki, Eman Saleh, Samia J Khoury, Salem Hannoun. Cumulative administrations of gadolinium-based contrast agents: risks of accumulation and toxicity of linear vs macrocyclic agents.
Critical reviews in toxicology.
2019 03; 49(3):262-279. doi:
10.1080/10408444.2019.1592109. [PMID: 30942117] - Fatma Beyazal Celiker, Levent Tumkaya, Tolga Mercantepe, Mehmet Beyazal, Arzu Turan, Hatice Beyazal Polat, Zehra Topal Suzan, Mehmet Fatih Inecikli, Kerimali Akyildiz, Adnan Yilmaz. Effects of Gadodiamide and Gadoteric Acid on Rat Kidneys: A Comparative Study.
Journal of magnetic resonance imaging : JMRI.
2019 02; 49(2):382-389. doi:
10.1002/jmri.26266. [PMID: 30209850] - Nathalie Fretellier, Agnès Granottier, Marlène Rasschaert, Anne-Laure Grindel, Fannie Baudimont, Philippe Robert, Jean-Marc Idée, Claire Corot. Does Age Interfere With Gadolinium Toxicity and Presence in Brain and Bone Tissues?: A Comparative Gadoterate Versus Gadodiamide Study in Juvenile and Adult Rats.
Investigative radiology.
2019 02; 54(2):61-71. doi:
10.1097/rli.0000000000000517. [PMID: 30394964] - Janina Boyken, Thomas Frenzel, Jessica Lohrke, Gregor Jost, Gunnar Schütz, Hubertus Pietsch. Impact of Treatment With Chelating Agents Depends on the Stability of Administered GBCAs: A Comparative Study in Rats.
Investigative radiology.
2019 02; 54(2):76-82. doi:
10.1097/rli.0000000000000522. [PMID: 30358694] - Francesca Arena, Paola Bardini, Francesco Blasi, Eliana Gianolio, Giada M Marini, Francesca La Cava, Giovanni Valbusa, Silvio Aime. Gadolinium presence, MRI hyperintensities, and glucose uptake in the hypoperfused rat brain after repeated administrations of gadodiamide.
Neuroradiology.
2019 Feb; 61(2):163-173. doi:
10.1007/s00234-018-2120-3. [PMID: 30377745] - Riccarda Delfino, Matteo Biasotto, Riccardo Candido, Matteo Altissimo, Marco Stebel, Murielle Salomè, Johannes T van Elteren, Katarina Vogel Mikuš, Cristina Zennaro, Martin Šala, Riccardo Addobbati, Giuliana Tromba, Lorella Pascolo. Gadolinium tissue deposition in the periodontal ligament of mice with reduced renal function exposed to Gd-based contrast agents.
Toxicology letters.
2019 Feb; 301(?):157-167. doi:
10.1016/j.toxlet.2018.11.014. [PMID: 30476537] - Worapol Ngamcherdtrakul, Jingga Morry, Thanapon Sangvanich, Moataz Reda, Daniel S Bejan, Glen E Fryxell, Wassana Yantasee. Removal of a gadolinium based contrast agent by a novel sorbent hemoperfusion in a chronic kidney disease (CKD) rodent model.
Scientific reports.
2019 01; 9(1):709. doi:
10.1038/s41598-018-37348-2. [PMID: 30679698] - John P Prybylski, Carla Coste Sanchez, Michael Jay. Impact of chelation timing on gadolinium deposition in rats after contrast administration.
Magnetic resonance imaging.
2019 01; 55(?):140-144. doi:
10.1016/j.mri.2018.10.006. [PMID: 30321663] - Shu-Ting Wang, Zheng-Xu Hua, Dong-Xiao Fan, Xin Zhang, Ke Ren. Gadolinium Retention and Clearance in the Diabetic Brain after Administrations of Gadodiamide, Gadopentetate Dimeglumine, and Gadoterate Meglumine in a Rat Model.
BioMed research international.
2019; 2019(?):3901907. doi:
10.1155/2019/3901907. [PMID: 31192255] - Tolga Mercantepe, Levent Tümkaya, Fatma Beyazal Çeliker, Zehra Topal Suzan, Seda Çinar, Kerimali Akyildiz, Filiz Mercantepe, Adnan Yilmaz. Effects of gadolinium-based MRI contrast agents on liver tissue.
Journal of magnetic resonance imaging : JMRI.
2018 11; 48(5):1367-1374. doi:
10.1002/jmri.26031. [PMID: 29607566] - Toshiaki Taoka, Gregor Jost, Thomas Frenzel, Shinji Naganawa, Hubertus Pietsch. Impact of the Glymphatic System on the Kinetic and Distribution of Gadodiamide in the Rat Brain: Observations by Dynamic MRI and Effect of Circadian Rhythm on Tissue Gadolinium Concentrations.
Investigative radiology.
2018 09; 53(9):529-534. doi:
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Andrologia.
2018 Aug; 50(6):e13031. doi:
10.1111/and.13031. [PMID: 29700836] - Philippe Robert, Stefanie Fingerhut, Cécile Factor, Véronique Vives, Justine Letien, Michael Sperling, Marlène Rasschaert, Robin Santus, Sébastien Ballet, Jean-Marc Idée, Claire Corot, Uwe Karst. One-year Retention of Gadolinium in the Brain: Comparison of Gadodiamide and Gadoterate Meglumine in a Rodent Model.
Radiology.
2018 08; 288(2):424-433. doi:
10.1148/radiol.2018172746. [PMID: 29786486] - Miski Aghnia Khairinisa, Yusuke Takatsuru, Izuki Amano, Khongorzul Erdene, Takahito Nakajima, Satomi Kameo, Hiroshi Koyama, Yoshito Tsushima, Noriyuki Koibuchi. The Effect of Perinatal Gadolinium-Based Contrast Agents on Adult Mice Behavior.
Investigative radiology.
2018 02; 53(2):110-118. doi:
10.1097/rli.0000000000000417. [PMID: 28915162] - A D Piersson, P N Gorleku. Nephrogenic systemic fibrosis: A survey of the use of gadolinium-based contrast agents in Ghana.
Radiography (London, England : 1995).
2017 Nov; 23(4):e108-e113. doi:
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Japanese journal of radiology.
2017 Oct; 35(10):568-573. doi:
10.1007/s11604-017-0667-2. [PMID: 28730467] - Thomas Frenzel, Chirag Apte, Gregor Jost, Laura Schöckel, Jessica Lohrke, Hubertus Pietsch. Quantification and Assessment of the Chemical Form of Residual Gadolinium in the Brain After Repeated Administration of Gadolinium-Based Contrast Agents: Comparative Study in Rats.
Investigative radiology.
2017 07; 52(7):396-404. doi:
10.1097/rli.0000000000000352. [PMID: 28125438] - Jessica Lohrke, Anna-Lena Frisk, Thomas Frenzel, Laura Schöckel, Martin Rosenbruch, Gregor Jost, Diana Constanze Lenhard, Martin A Sieber, Volker Nischwitz, Astrid Küppers, Hubertus Pietsch. Histology and Gadolinium Distribution in the Rodent Brain After the Administration of Cumulative High Doses of Linear and Macrocyclic Gadolinium-Based Contrast Agents.
Investigative radiology.
2017 06; 52(6):324-333. doi:
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Investigative radiology.
2017 05; 52(5):255-264. doi:
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Magnetic resonance imaging.
2017 05; 38(?):145-151. doi:
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Advances in chronic kidney disease.
2017 05; 24(3):176-182. doi:
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Radiology.
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The Journal of toxicological sciences.
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Magnetic resonance imaging.
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Investigative radiology.
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Investigative radiology.
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Magnetic resonance imaging.
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Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine.
2014; 13(2):89-95. doi:
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AJR. American journal of roentgenology.
2013 Nov; 201(5):1041-8. doi:
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AJR. American journal of roentgenology.
2013 Aug; 201(2):W292-6. doi:
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Radiology.
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AJNR. American journal of neuroradiology.
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Journal of controlled release : official journal of the Controlled Release Society.
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Magnetic resonance imaging.
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Journal of computer assisted tomography.
2012 Nov; 36(6):669-74. doi:
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Human & experimental toxicology.
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British journal of pharmacology.
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AJR. American journal of roentgenology.
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Investigative radiology.
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European journal of radiology.
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AJR. American journal of roentgenology.
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Clinical biochemistry.
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Radiology.
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Investigative radiology.
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European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
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Annals of vascular surgery.
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The American journal of the medical sciences.
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Academic radiology.
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Magnetic resonance in medicine.
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JACC. Cardiovascular imaging.
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Journal of computer assisted tomography.
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International journal of cardiology.
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Investigative radiology.
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Magnetic resonance in medicine.
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The British journal of radiology.
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Journal of computer assisted tomography.
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Magnetic resonance in medicine.
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Clinical journal of the American Society of Nephrology : CJASN.
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AJR. American journal of roentgenology.
2010 Mar; 194(3):790-3. doi:
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European radiology.
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Journal of the American Academy of Dermatology.
2010 Feb; 62(2):337-42. doi:
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