n-Hexadecylphosphonocholine (BioDeep_00000900636)

   


代谢物信息卡片


n-Hexadecylphosphonocholine

化学式: C21H47NO4P+ (408.32425320000004)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCCCCCCCCCCCCOP(=O)(O)OCC[N+](C)(C)C
InChI: InChI=1S/C21H46NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-25-27(23,24)26-21-19-22(2,3)4/h5-21H2,1-4H3/p+1

描述信息

同义名列表

1 个代谢物同义名

n-Hexadecylphosphonocholine



数据库引用编号

2 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Lais Alonso, Sebastião Antônio Mendanha, Cássia Alessandra Marquezin, Marina Berardi, Amando Siuiti Ito, A Ulises Acuña, Antonio Alonso. Interaction of miltefosine with intercellular membranes of stratum corneum and biomimetic lipid vesicles. International journal of pharmaceutics. 2012 Sep; 434(1-2):391-8. doi: 10.1016/j.ijpharm.2012.06.006. [PMID: 22692081]
  • Guilherme Carneiro, Marta Gontijo Aguiar, Ana Paula Fernandes, Lucas Antônio Miranda Ferreira. Drug delivery systems for the topical treatment of cutaneous leishmaniasis. Expert opinion on drug delivery. 2012 Sep; 9(9):1083-97. doi: 10.1517/17425247.2012.701204. [PMID: 22724539]
  • Paulo R G de Freitas-Junior, Carolina M C Catta-Preta, Iamara da Silva Andrade, Danielle P Cavalcanti, Wanderley de Souza, Marcelo Einicker-Lamas, Maria Cristina M Motta. Effects of miltefosine on the proliferation, ultrastructure, and phospholipid composition of Angomonas deanei, a trypanosomatid protozoan that harbors a symbiotic bacterium. FEMS microbiology letters. 2012 Aug; 333(2):129-37. doi: 10.1111/j.1574-6968.2012.02607.x. [PMID: 22651853]
  • Laurent Imbert, Mathieu Gaudin, Danielle Libong, David Touboul, Sonia Abreu, Philippe M Loiseau, Olivier Laprévote, Pierre Chaminade. Comparison of electrospray ionization, atmospheric pressure chemical ionization and atmospheric pressure photoionization for a lipidomic analysis of Leishmania donovani. Journal of chromatography. A. 2012 Jun; 1242(?):75-83. doi: 10.1016/j.chroma.2012.04.035. [PMID: 22560453]
  • Nisha Singh, Manish Kumar, Rakesh Kumar Singh. Leishmaniasis: current status of available drugs and new potential drug targets. Asian Pacific journal of tropical medicine. 2012 Jun; 5(6):485-97. doi: 10.1016/s1995-7645(12)60084-4. [PMID: 22575984]
  • K Pandey, S B Pun, B D Pandey. Relapse of kala-azar after use of multiple drugs: a case report and brief review of literature. Indian journal of medical microbiology. 2012 Apr; 30(2):227-9. doi: 10.4103/0255-0857.96703. [PMID: 22664444]
  • Alak Manna, Piu Saha, Avijit Sarkar, Debanjan Mukhopadhyay, Ajay K Bauri, Deepak Kumar, Padma Das, Subrata Chattopadhyay, Mitali Chatterjee. Malabaricone-A induces a redox imbalance that mediates apoptosis in U937 cell line. PloS one. 2012; 7(5):e36938. doi: 10.1371/journal.pone.0036938. [PMID: 22590637]
  • Rosa L López-Marqués, Lisbeth R Poulsen, Michael G Palmgren. A putative plant aminophospholipid flippase, the Arabidopsis P4 ATPase ALA1, localizes to the plasma membrane following association with a β-subunit. PloS one. 2012; 7(4):e33042. doi: 10.1371/journal.pone.0033042. [PMID: 22514601]
  • Adriana Oliveira Dos Santos, Tânia Ueda-Nakamura, Benedito Prado Dias Filho, Valdir Florêncio da Veiga Junior, Celso Vataru Nakamura. Copaiba Oil: An Alternative to Development of New Drugs against Leishmaniasis. Evidence-based complementary and alternative medicine : eCAM. 2012; 2012(?):898419. doi: 10.1155/2012/898419. [PMID: 21716677]
  • Pramod Kumar Kushawaha, Reema Gupta, Chandra Dev Pati Tripathi, Shyam Sundar, Anuradha Dube. Evaluation of Leishmania donovani protein disulfide isomerase as a potential immunogenic protein/vaccine candidate against visceral Leishmaniasis. PloS one. 2012; 7(4):e35670. doi: 10.1371/journal.pone.0035670. [PMID: 22539989]
  • Meenakshi Sharma, Rakesh Sehgal, Sukhbir Kaur. Evaluation of nephroprotective and immunomodulatory activities of antioxidants in combination with cisplatin against murine visceral leishmaniasis. PLoS neglected tropical diseases. 2012; 6(5):e1629. doi: 10.1371/journal.pntd.0001629. [PMID: 22563510]
  • Maja Ø Vase, Ylva K Hellberg, Carsten S Larsen, Eskild Petersen, Henrik Schaumburg, Knud Bendix, Christophe Ravel, Patrick Bastien, Mariann Christensen, Francesco d'Amore. Development of splenic marginal zone lymphoma in a HIV-negative patient with visceral leishmaniasis. Acta haematologica. 2012; 128(1):20-2. doi: 10.1159/000337341. [PMID: 22572474]
  • Rubén E Varela-M, Janny A Villa-Pulgarin, Edward Yepes, Ingrid Müller, Manuel Modolell, Diana L Muñoz, Sara M Robledo, Carlos E Muskus, Julio López-Abán, Antonio Muro, Iván D Vélez, Faustino Mollinedo. In vitro and in vivo efficacy of ether lipid edelfosine against Leishmania spp. and SbV-resistant parasites. PLoS neglected tropical diseases. 2012; 6(4):e1612. doi: 10.1371/journal.pntd.0001612. [PMID: 22506086]
  • L Imbert, R G Ramos, D Libong, S Abreu, P M Loiseau, P Chaminade. Identification of phospholipid species affected by miltefosine action in Leishmania donovani cultures using LC-ELSD, LC-ESI/MS, and multivariate data analysis. Analytical and bioanalytical chemistry. 2012 Jan; 402(3):1169-82. doi: 10.1007/s00216-011-5520-3. [PMID: 22065347]
  • Weili Sun, Shakeel Modak. Emerging treatment options for the treatment of neuroblastoma: potential role of perifosine. OncoTargets and therapy. 2012; 5(?):21-9. doi: 10.2147/ott.s14578. [PMID: 22419878]
  • Adrien Weingärtner, Gerdi Kemmer, Frederic D Müller, Ricardo Andrade Zampieri, Marcos Gonzaga dos Santos, Jürgen Schiller, Thomas Günther Pomorski. Leishmania promastigotes lack phosphatidylserine but bind annexin V upon permeabilization or miltefosine treatment. PloS one. 2012; 7(8):e42070. doi: 10.1371/journal.pone.0042070. [PMID: 22870283]
  • B Gustavo Benaim, Célia R S Garcia. Targeting calcium homeostasis as the therapy of Chagas' disease and leishmaniasis - a review. Tropical biomedicine. 2011 Dec; 28(3):471-81. doi: NULL. [PMID: 22433874]
  • Ana Marta Silva, Anabela Cordeiro-da-Silva, Graham H Coombs. Metabolic variation during development in culture of Leishmania donovani promastigotes. PLoS neglected tropical diseases. 2011 Dec; 5(12):e1451. doi: 10.1371/journal.pntd.0001451. [PMID: 22206037]
  • Soon Goo Lee, William Haakenson, James P McCarter, D Jeremy Williams, Michelle C Hresko, Joseph M Jez. Thermodynamic evaluation of ligand binding in the plant-like phosphoethanolamine methyltransferases of the parasitic nematode Haemonchus contortus. The Journal of biological chemistry. 2011 Nov; 286(44):38060-38068. doi: 10.1074/jbc.m111.290619. [PMID: 21914812]
  • Hasan Kirmizibekmez, Irem Atay, Marcel Kaiser, Erdem Yesilada, Deniz Tasdemir. In vitro antiprotozoal activity of extracts of five Turkish Lamiaceae species. Natural product communications. 2011 Nov; 6(11):1697-700. doi: . [PMID: 22224291]
  • Debanjan Mukhopadhyay, Nilay Kanti Das, Susmita Roy, Sunanda Kundu, J N Barbhuiya, Mitali Chatterjee. Miltefosine effectively modulates the cytokine milieu in Indian post kala-azar dermal leishmaniasis. The Journal of infectious diseases. 2011 Nov; 204(9):1427-36. doi: 10.1093/infdis/jir551. [PMID: 21933878]
  • J-H Ch'ng, K Liew, A S-P Goh, E Sidhartha, K S-W Tan. Drug-induced permeabilization of parasite's digestive vacuole is a key trigger of programmed cell death in Plasmodium falciparum. Cell death & disease. 2011 Oct; 2(?):e216. doi: 10.1038/cddis.2011.97. [PMID: 21993392]
  • Shahram Khademvatan, Mohammad Javad Gharavi, Jasem Saki. Miltefosine induces metacaspase and PARP genes expression in Leishmania infantum. The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. 2011 Sep; 15(5):442-8. doi: 10.1016/s1413-8670(11)70225-2. [PMID: 22230850]
  • Florian Astelbauer, Andreas Obwaller, Adriane Raninger, Brigitte Brem, Harald Greger, Michael Duchêne, Walther Wernsdorfer, Julia Walochnik. Anti-leishmanial activity of plant-derived acridones, flavaglines, and sulfur-containing amides. Vector borne and zoonotic diseases (Larchmont, N.Y.). 2011 Jul; 11(7):793-8. doi: 10.1089/vbz.2010.0087. [PMID: 21417924]
  • José Batista, Georg Schlechtingen, Tim Friedrichson, Tobias Braxmeier, Jürgen Bajorath. Lipid-like sulfoxides and amine oxides as inhibitors of mast cell activation. European journal of medicinal chemistry. 2011 Jun; 46(6):2147-51. doi: 10.1016/j.ejmech.2011.02.068. [PMID: 21421276]
  • F Mollinedo, M Fernández, V Hornillos, J Delgado, F Amat-Guerri, A U Acuña, T Nieto-Miguel, J A Villa-Pulgarín, C González-García, V Ceña, C Gajate. Involvement of lipid rafts in the localization and dysfunction effect of the antitumor ether phospholipid edelfosine in mitochondria. Cell death & disease. 2011 May; 2(?):e158. doi: 10.1038/cddis.2011.41. [PMID: 21593790]
  • Vinod Kumar, Jalaj Kumar Gour, Surabhi Bajpai, Manish Mishra, Rakesh Kumar Singh. Detection of urinary antigens and their seroreactivity with serum of patients in Leishmania donovani infection. Asian Pacific journal of tropical medicine. 2011 May; 4(5):367-70. doi: 10.1016/s1995-7645(11)60105-3. [PMID: 21771678]
  • Sara Teixeira de Macedo-Silva, Thais Larissa Araújo de Oliveira Silva, Julio A Urbina, Wanderley de Souza, Juliany Cola Fernandes Rodrigues. Antiproliferative, Ultrastructural, and Physiological Effects of Amiodarone on Promastigote and Amastigote Forms of Leishmania amazonensis. Molecular biology international. 2011; 2011(?):876021. doi: 10.4061/2011/876021. [PMID: 22091415]
  • Partha Roy, Suvadra Das, Tanmoy Bera, Subhasis Mondol, Arup Mukherjee. Andrographolide nanoparticles in leishmaniasis: characterization and in vitro evaluations. International journal of nanomedicine. 2010 Dec; 5(?):1113-21. doi: 10.2147/ijn.s14787. [PMID: 21270962]
  • Ellen K Wasan, Pavel Gershkovich, Jinying Zhao, Xiaohua Zhu, Karl Werbovetz, Richard R Tidwell, John G Clement, Sheila J Thornton, Kishor M Wasan. A novel tropically stable oral amphotericin B formulation (iCo-010) exhibits efficacy against visceral Leishmaniasis in a murine model. PLoS neglected tropical diseases. 2010 Dec; 4(12):e913. doi: 10.1371/journal.pntd.0000913. [PMID: 21151883]
  • Ruben t'Kindt, Richard A Scheltema, Andris Jankevics, Kirstyn Brunker, Suman Rijal, Jean-Claude Dujardin, Rainer Breitling, David G Watson, Graham H Coombs, Saskia Decuypere. Metabolomics to unveil and understand phenotypic diversity between pathogen populations. PLoS neglected tropical diseases. 2010 Nov; 4(11):e904. doi: 10.1371/journal.pntd.0000904. [PMID: 21152055]
  • Antonio Jiménez-Ruiz, Juan Fernando Alzate, Ewan Thomas Macleod, Carsten Günter Kurt Lüder, Nicolas Fasel, Hilary Hurd. Apoptotic markers in protozoan parasites. Parasites & vectors. 2010 Nov; 3(?):104. doi: 10.1186/1756-3305-3-104. [PMID: 21062457]
  • S Dölle, D Hoser, C Rasche, C Loddenkemper, M Maurer, T Zuberbier, M Worm. Long-term reduction in local inflammation by a lipid raft molecule in atopic dermatitis. Allergy. 2010 Sep; 65(9):1158-65. doi: 10.1111/j.1398-9995.2010.02341.x. [PMID: 20337610]
  • Adrien Weingärtner, Björn Drobot, Andreas Herrmann, María P Sánchez-Cañete, Francisco Gamarro, Santiago Castanys, Thomas Günther Pomorski. Disruption of the lipid-transporting LdMT-LdRos3 complex in Leishmania donovani affects membrane lipid asymmetry but not host cell invasion. PloS one. 2010 Aug; 5(8):e12443. doi: 10.1371/journal.pone.0012443. [PMID: 20865154]
  • Iván Vélez, Liliana López, Ximena Sánchez, Laureano Mestra, Carlos Rojas, Erwin Rodríguez. Efficacy of miltefosine for the treatment of American cutaneous leishmaniasis. The American journal of tropical medicine and hygiene. 2010 Aug; 83(2):351-6. doi: 10.4269/ajtmh.2010.10-0060. [PMID: 20682881]
  • E Palumbo. Visceral leishmaniasis in children: a review. Minerva pediatrica. 2010 Aug; 62(4):389-95. doi: ". [PMID: 20940672]
  • Jan Rybniker, Valentin Goede, Jessica Mertens, Monika Ortmann, Wolfgang Kulas, Matthias Kochanek, Thomas Benzing, José R Arribas, Gerd Fätkenheuer. Treatment of visceral leishmaniasis with intravenous pentamidine and oral fluconazole in an HIV-positive patient with chronic renal failure--a case report and brief review of the literature. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2010 Jun; 14(6):e522-5. doi: 10.1016/j.ijid.2009.06.010. [PMID: 19726213]
  • José Batista, Tim Friedrichson, Georg Schlechtingen, Tobias Braxmeier, Gary Jennings, Jürgen Bajorath. Computational screening for membrane-directed inhibitors of mast cell activation. European journal of medicinal chemistry. 2010 Jun; 45(6):2700-4. doi: 10.1016/j.ejmech.2010.01.061. [PMID: 20153565]
  • Faustino Mollinedo, Janis de la Iglesia-Vicente, Consuelo Gajate, Ander Estella-Hermoso de Mendoza, Janny A Villa-Pulgarin, Mercè de Frias, Gaël Roué, Joan Gil, Dolors Colomer, Miguel A Campanero, Maria J Blanco-Prieto. In vitro and In vivo selective antitumor activity of Edelfosine against mantle cell lymphoma and chronic lymphocytic leukemia involving lipid rafts. Clinical cancer research : an official journal of the American Association for Cancer Research. 2010 Apr; 16(7):2046-54. doi: 10.1158/1078-0432.ccr-09-2456. [PMID: 20233887]
  • José M Jiménez-López, Pablo Ríos-Marco, Carmen Marco, Josefa L Segovia, María P Carrasco. Alterations in the homeostasis of phospholipids and cholesterol by antitumor alkylphospholipids. Lipids in health and disease. 2010 Mar; 9(?):33. doi: 10.1186/1476-511x-9-33. [PMID: 20338039]
  • Kathryn M Castorena, Kenneth A Stapleford, David J Miller. Complementary transcriptomic, lipidomic, and targeted functional genetic analyses in cultured Drosophila cells highlight the role of glycerophospholipid metabolism in Flock House virus RNA replication. BMC genomics. 2010 Mar; 11(?):183. doi: 10.1186/1471-2164-11-183. [PMID: 20236518]
  • Wolfgang Bäumer, Piotr Wlaź, Gary Jennings, Chris Rundfeldt. The putative lipid raft modulator miltefosine displays immunomodulatory action in T-cell dependent dermal inflammation models. European journal of pharmacology. 2010 Feb; 628(1-3):226-32. doi: 10.1016/j.ejphar.2009.11.018. [PMID: 19917276]
  • Milos Lukác, Martin Mrva, Eva Fischer-Fodor, Ivan Lacko, Marián Bukovský, Natalia Miklásová, Frantisek Ondriska, Ferdinand Devínsky. Synthesis and biological activity of dialkylphosphocholines. Bioorganic & medicinal chemistry letters. 2009 Nov; 19(22):6346-9. doi: 10.1016/j.bmcl.2009.09.079. [PMID: 19818608]
  • M Saint-Pierre-Chazalet, M Ben Brahim, L Le Moyec, C Bories, M Rakotomanga, P M Loiseau. Membrane sterol depletion impairs miltefosine action in wild-type and miltefosine-resistant Leishmania donovani promastigotes. The Journal of antimicrobial chemotherapy. 2009 Nov; 64(5):993-1001. doi: 10.1093/jac/dkp321. [PMID: 19749205]
  • Guido Henke, Lars H Lindner, Michael Vogeser, Hans-Jörg Eibl, Jürgen Wörner, Arndt C Müller, Michael Bamberg, Kirsten Wachholz, Claus Belka, Verena Jendrossek. Pharmacokinetics and biodistribution of Erufosine in nude mice--implications for combination with radiotherapy. Radiation oncology (London, England). 2009 Oct; 4(?):46. doi: 10.1186/1748-717x-4-46. [PMID: 19852786]
  • Neeloo Singh, Jaspreet Kaur, Pranav Kumar, Swati Gupta, Nasib Singh, Angana Ghosal, Avijit Dutta, Ashutosh Kumar, Ramapati Tripathi, Mohammad Imran Siddiqi, Chitra Mandal, Anuradha Dube. An orally effective dihydropyrimidone (DHPM) analogue induces apoptosis-like cell death in clinical isolates of Leishmania donovani overexpressing pteridine reductase 1. Parasitology research. 2009 Oct; 105(5):1317-25. doi: 10.1007/s00436-009-1557-z. [PMID: 19621245]
  • Paolo Bianciardi, Claudio Brovida, Marialuisa Valente, Luca Aresu, Laura Cavicchioli, Claudia Vischer, Lucie Giroud, Massimo Castagnaro. Administration of miltefosine and meglumine antimoniate in healthy dogs: clinicopathological evaluation of the impact on the kidneys. Toxicologic pathology. 2009 Oct; 37(6):770-5. doi: 10.1177/0192623309344088. [PMID: 19690151]
  • Guadalupe Miró, Gaetano Oliva, Israel Cruz, Carmen Cañavate, Michele Mortarino, Claudia Vischer, Paolo Bianciardi. Multicentric, controlled clinical study to evaluate effectiveness and safety of miltefosine and allopurinol for canine leishmaniosis. Veterinary dermatology. 2009 Oct; 20(5-6):397-404. doi: 10.1111/j.1365-3164.2009.00824.x. [PMID: 20178476]
  • Serge de Vallière, Charles Mary, Jeanna E Joneberg, Samuel Rotman, Roberto Bullani, Gilbert Greub, Julian D Gillmore, Pierre A Buffet, Philip E Tarr. AA-amyloidosis caused by visceral leishmaniasis in a human immunodeficiency virus-infected patient. The American journal of tropical medicine and hygiene. 2009 Aug; 81(2):209-12. doi: 10.4269/ajtmh.2009.81.209. [PMID: 19635871]
  • Carmen Marco, José M Jiménez-López, Pablo Ríos-Marco, Josefa L Segovia, María P Carrasco. Hexadecylphosphocholine alters nonvesicular cholesterol traffic from the plasma membrane to the endoplasmic reticulum and inhibits the synthesis of sphingomyelin in HepG2 cells. The international journal of biochemistry & cell biology. 2009 Jun; 41(6):1296-303. doi: 10.1016/j.biocel.2008.11.004. [PMID: 19084611]
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  • Richa Tewari, Vivek Sharma, Nitin Koul, Ellora Sen. Involvement of miltefosine-mediated ERK activation in glioma cell apoptosis through Fas regulation. Journal of neurochemistry. 2008 Nov; 107(3):616-27. doi: 10.1111/j.1471-4159.2008.05625.x. [PMID: 18710416]
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  • María P Carrasco, José M Jiménez-López, Josefa L Segovia, Carmen Marco. Hexadecylphosphocholine interferes with the intracellular transport of cholesterol in HepG2 cells. The FEBS journal. 2008 Apr; 275(8):1675-86. doi: 10.1111/j.1742-4658.2008.06322.x. [PMID: 18312412]
  • Thomas P C Dorlo, Michel J X Hillebrand, Hilde Rosing, Teunis A Eggelte, Peter J de Vries, Jos H Beijnen. Development and validation of a quantitative assay for the measurement of miltefosine in human plasma by liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2008 Apr; 865(1-2):55-62. doi: 10.1016/j.jchromb.2008.02.005. [PMID: 18325856]
  • Theodora Calogeropoulou, Panagiotis Angelou, Anastasia Detsi, Irene Fragiadaki, Effie Scoulica. Design and synthesis of potent antileishmanial cycloalkylidene-substituted ether phospholipid derivatives. Journal of medicinal chemistry. 2008 Feb; 51(4):897-908. doi: 10.1021/jm701166b. [PMID: 18220332]
  • Francisco Muñoz-Martínez, Cristina Torres, Santiago Castanys, Francisco Gamarro. The anti-tumor alkylphospholipid perifosine is internalized by an ATP-dependent translocase activity across the plasma membrane of human KB carcinoma cells. Biochimica et biophysica acta. 2008 Feb; 1778(2):530-40. doi: 10.1016/j.bbamem.2007.10.017. [PMID: 18005660]
  • Emilio Palumbo. Oral miltefosine treatment in children with visceral leishmaniasis: a brief review. The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. 2008 Feb; 12(1):2-4. doi: 10.1590/s1413-86702008000100002. [PMID: 18553005]
  • Lars H Lindner, Martin Hossann, Michael Vogeser, Nicole Teichert, Kirsten Wachholz, Hansjoerg Eibl, Wolfgang Hiddemann, Rolf D Issels. Dual role of hexadecylphosphocholine (miltefosine) in thermosensitive liposomes: active ingredient and mediator of drug release. Journal of controlled release : official journal of the Controlled Release Society. 2008 Jan; 125(2):112-20. doi: 10.1016/j.jconrel.2007.10.009. [PMID: 18022271]
  • Wim J van Blitterswijk, Marcel Verheij. Anticancer alkylphospholipids: mechanisms of action, cellular sensitivity and resistance, and clinical prospects. Current pharmaceutical design. 2008; 14(21):2061-74. doi: 10.2174/138161208785294636. [PMID: 18691116]
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