1alpha,24(R),25-trihydroxyvitamin D3 (BioDeep_00000900359)
代谢物信息卡片
1alpha,24(R),25-trihydroxyvitamin D3
化学式: C27H44O4 (432.3239424)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(CCC(C(C)(C)O)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C
InChI: InChI=1S/C27H44O4/c1-17(8-13-25(30)26(3,4)31)22-11-12-23-19(7-6-14-27(22,23)5)9-10-20-15-21(28)16-24(29)18(20)2/h9-10,17,21-25,28-31H,2,6-8,11-16H2,1,3-5H3/b19-9+,20-10+/t17-,21-,22-,23+,24+,25-,27-/m1/s1
描述信息
D018977 - Micronutrients > D014815 - Vitamins > D006887 - Hydroxycholecalciferols
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代谢反应
0 个相关的代谢反应过程信息。
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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文献列表
- Kay W Colston, Lorraine C Lowe, Janine L Mansi, Moray J Campbell. Vitamin D status and breast cancer risk.
Anticancer research.
2006 Jul; 26(4A):2573-80. doi:
NULL. [PMID: 16886666] - R G Erben, U Bante, H Birner, M Stangassinger. Prophylactic effects of 1,24,25-trihydroxyvitamin D3 on ovariectomy-induced cancellous bone loss in the rat.
Calcified tissue international.
1997 May; 60(5):434-40. doi:
10.1007/s002239900259. [PMID: 9115161] - H Ishida, C G Bellows, J E Aubin, J N Heersche. Characterization of the 1,25-(OH)2D3-induced inhibition of bone nodule formation in long-term cultures of fetal rat calvaria cells.
Endocrinology.
1993 Jan; 132(1):61-6. doi:
10.1210/endo.132.1.8419147. [PMID: 8419147] - R G Erben, H Weiser, F Sinowatz, W A Rambeck, H Zucker. Vitamin D metabolites prevent vertebral osteopenia in ovariectomized rats.
Calcified tissue international.
1992 Mar; 50(3):228-36. doi:
10.1007/bf00296287. [PMID: 1617497] - R G Erben, B Kohn, H Weiser, F Sinowatz, W A Rambeck. Role of vitamin D metabolites in the prevention of the osteopenia induced by ovariectomy in the axial and appendicular skeleton of the rat.
Zeitschrift fur Ernahrungswissenschaft.
1990 Dec; 29(4):229-48. doi:
10.1007/bf02023080. [PMID: 2080635] - K Törnquist, L Forss, C Lamberg-Allardt. Effects of vitamin D3 metabolites on thyrotropin secretion from rat pituitary cells in culture.
Journal of endocrinological investigation.
1990 May; 13(5):391-5. doi:
10.1007/bf03350686. [PMID: 2380504] - V K Bauman, M Iu Valinietse, D A Babarykin. [Effect of strontium on the anti-rickets activity of vitamin D3 and its hydroxy analogs].
Voprosy meditsinskoi khimii.
1988 Jul; 34(4):26-32. doi:
NULL. [PMID: 2848362] - R L Boland, M I Skliar, A W Norman. Isolation of vitamin D3 metabolites from Solanum malacoxylon leaf extracts incubated with ruminal fluid.
Planta medica.
1987 Apr; 53(2):161-4. doi:
10.1055/s-2006-962662. [PMID: 3602141] - A Fournier, M Garabedian, I Grégoire, J L Sebert, A Pruna. [Vitamin D: metabolism and biological properties].
Annales de medecine interne.
1985; 136(2):154-63. doi:
NULL. [PMID: 3000251] - J L Napoli, C A Martin. Production of C-24- and C-23-oxidized metabolites of 1,25-dihydroxycholecalciferol by cultured kidney cells (LLC PK1) and their presence in kidney in vivo.
The Biochemical journal.
1984 May; 219(3):713-7. doi:
10.1042/bj2190713. [PMID: 6547601] - S Ishizuka, S Ishimoto, A W Norman. Isolation and identification of 1 alpha,25-dihydroxy-24-oxovitamin D3, 1 alpha,25-dihydroxyvitamin D3 26,23-lactone, and 1 alpha,24(S),25-trihydroxyvitamin D3: in vivo metabolites of 1 alpha,25-dihydroxyvitamin D3.
Biochemistry.
1984 Mar; 23(7):1473-8. doi:
10.1021/bi00302a021. [PMID: 6547052] - K Hove. Effects of 1 alpha-hydroxylated metabolites of cholecalciferol on intestinal radiocalcium absorption in goats.
The British journal of nutrition.
1984 Jan; 51(1):157-64. doi:
10.1079/bjn19840017. [PMID: 6546296] - R L Prince, J D Wark, J A Eisman, J A Danks, R G Larkins. Opposing effects of cyclic adenosine-3',5'-monophosphate and cyclic guanosine-3',5'-monophosphate on the metabolism of 24-hydroxyvitamin D3 in isolated chick renal tubules.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
1983 Aug; 15(8):399-403. doi:
10.1055/s-2007-1018734. [PMID: 6311708] - R L Horst, K Hove, E T Littledike, T A Reinhardt, M R Uskokovic, J J Partridge. Plasma concentrations of 1,25-dihydroxyvitamin D, 1,24R,25-trihydroxyvitamin D3, and 2,25,26-trihydroxyvitamin D3 after their administration to dairy cows.
Journal of dairy science.
1983 Jul; 66(7):1455-60. doi:
10.3168/jds.s0022-0302(83)81959-6. [PMID: 6688433] - K Hove, R L Horst, E T Littledike. Effects of 1 alpha-hydroxyvitamin D3, 1,25-dihydroxyvitamin D3, 1,24,25-trihydroxyvitamin D3, and 1,25,26-trihydroxyvitamin D3 on mineral metabolism and 1,25-dihydroxyvitamin D concentrations in dairy cows.
Journal of dairy science.
1983 Jan; 66(1):59-66. doi:
10.3168/jds.s0022-0302(83)81753-6. [PMID: 6687602] - T L Clemens, L J Fraher, L M Sandler, J L O'Riordan. Demonstration of circulating 1,24,25-trihydroxyvitamin D3 in man by radioimmunoassay.
Clinical endocrinology.
1982 Apr; 16(4):337-43. doi:
10.1111/j.1365-2265.1982.tb00725.x. [PMID: 6284410] - J S Chandler, J W Pike, M R Haussler. Biosynthesis, purification and receptor binding properties of high specific radioactivity 1 alpha, 24(R),25-trihydroxy-[26,27-methyl-3H]-vitamin D3.
Journal of steroid biochemistry.
1982 Feb; 16(2):303-10. doi:
10.1016/0022-4731(82)90181-9. [PMID: 6281579] - J M Garel, A C Delorme, P Marche, T M Nguyen, M Garabedian. Vitamin D3 metabolite injections to thyroparathyroidectomized pregnant rats: effects on calcium-binding proteins of maternal duodenum and of fetoplacental unit.
Endocrinology.
1981 Jul; 109(1):284-9. doi:
10.1210/endo-109-1-284. [PMID: 6263587] - S Ishizuka, T Naruchi, Y Hashimoto, H Orimo. Radioreceptor assay for 1 alpha,24(R)25-trihydroxyvitamin D3 in human serum.
Journal of nutritional science and vitaminology.
1981; 27(1):71-5. doi:
10.3177/jnsv.27.71. [PMID: 6974773] - A Boris, J F Hurley, T Trmal. In vivo mobilization of bone calcium in thyroparathyroidectomized rats by 1 alpha, 25-dihydroxycholecalciferol (calcitriol) and related compounds.
The Journal of nutrition.
1980 Nov; 110(11):2291-6. doi:
10.1093/jn/110.11.2291. [PMID: 6893603] - D D Bikle. Studies of the chick renal mitochondrial 25-hydroxyvitamin D-3 24-hydroxylase.
Biochimica et biophysica acta.
1980 Sep; 615(1):208-22. doi:
10.1016/0005-2744(80)90024-8. [PMID: 6775702] - M R Haussler, J S Chandler, L A Hagan, J W Pike. Use of chick kidney to enzymatically generate radiolabeled 1,25-dihydroxyvitamin D and other vitamin D metabolites.
Methods in enzymology.
1980; 67(?):529-42. doi:
10.1016/s0076-6879(80)67066-9. [PMID: 6966030] - Y Tanaka, L Castillo, H F DeLuca. The 24-hydroxylation of 1,25-dihydroxyvitamin D3.
The Journal of biological chemistry.
1977 Feb; 252(4):1421-4. doi:
. [PMID: 838723]