5alpha,9alpha,10beta-Labda-8(20),13-dien-15-yl diphosphate(3-) (BioDeep_00000898810)

   


代谢物信息卡片


5alpha,9alpha,10beta-Labda-8(20),13-dien-15-yl diphosphate(3-)

化学式: C20H33O7P2-3 (447.1701428)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 66.67%

分子结构信息

SMILES: CC(=CCOP(=O)([O-])OP(=O)([O-])[O-])CCC1C(=C)CCC2C1(CCCC2(C)C)C
InChI: InChI=1S/C20H36O7P2/c1-15(11-14-26-29(24,25)27-28(21,22)23)7-9-17-16(2)8-10-18-19(3,4)12-6-13-20(17,18)5/h11,17-18H,2,6-10,12-14H2,1,3-5H3,(H,24,25)(H2,21,22,23)/p-3/b15-11+/t17-,18-,20+/m0/s1

描述信息

同义名列表

1 个代谢物同义名

5alpha,9alpha,10beta-Labda-8(20),13-dien-15-yl diphosphate(3-)



数据库引用编号

2 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(2)

PlantCyc(2)

代谢反应

14 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(6)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(8)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Jianduo Zhang, Lu Zhang, Chengwei Zhang, Yongxing Yang, Huayin Liu, Lu Li, Shengxue Zhang, Xianggan Li, Xinxiang Liu, Ya Liu, Jin Wang, Guangyu Yang, Qingyou Xia, Weiguang Wang, Jinxiao Yang. Developing an efficient and visible prime editing system to restore tobacco 8-hydroxy-copalyl diphosphate gene for labdane diterpene Z-abienol biosynthesis. Science China. Life sciences. 2023 Dec; 66(12):2910-2921. doi: 10.1007/s11427-022-2396-x. [PMID: 37460713]
  • Jeffrey D Rudolf, Liao-Bin Dong, Hongnan Cao, Catherine Hatzos-Skintges, Jerzy Osipiuk, Michael Endres, Chin-Yuan Chang, Ming Ma, Gyorgy Babnigg, Andrzej Joachimiak, George N Phillips, Ben Shen. Structure of the ent-Copalyl Diphosphate Synthase PtmT2 from Streptomyces platensis CB00739, a Bacterial Type II Diterpene Synthase. Journal of the American Chemical Society. 2016 08; 138(34):10905-15. doi: 10.1021/jacs.6b04317. [PMID: 27490479]
  • Xin Zhan, Søren Spanner Bach, Nikolaj Lervad Hansen, Christina Lunde, Henrik Toft Simonsen. Additional diterpenes from Physcomitrella patens synthesized by copalyl diphosphate/kaurene synthase (PpCPS/KS). Plant physiology and biochemistry : PPB. 2015 Nov; 96(?):110-4. doi: 10.1016/j.plaphy.2015.07.011. [PMID: 26248039]
  • Manami Shimane, Yohei Ueno, Keiko Morisaki, Shingo Oogami, Masahiro Natsume, Ken-Ichiro Hayashi, Hiroshi Nozaki, Hiroshi Kawaide. Molecular evolution of the substrate specificity of ent-kaurene synthases to adapt to gibberellin biosynthesis in land plants. The Biochemical journal. 2014 Sep; 462(3):539-46. doi: 10.1042/bj20140134. [PMID: 24983886]
  • Philipp Zerbe, Angela Chiang, Harpreet Dullat, Mark O'Neil-Johnson, Courtney Starks, Björn Hamberger, Jörg Bohlmann. Diterpene synthases of the biosynthetic system of medicinally active diterpenoids in Marrubium vulgare. The Plant journal : for cell and molecular biology. 2014 Sep; 79(6):914-27. doi: 10.1111/tpj.12589. [PMID: 24990389]
  • Jun-Ling Li, Qian-Qian Chen, Qiu-Ping Jin, Juan Gao, Pei-Ji Zhao, Shan Lu, Ying Zeng. IeCPS2 is potentially involved in the biosynthesis of pharmacologically active Isodon diterpenoids rather than gibberellin. Phytochemistry. 2012 Apr; 76(?):32-9. doi: 10.1016/j.phytochem.2011.12.021. [PMID: 22284743]
  • Philipp Zerbe, Angela Chiang, Jörg Bohlmann. Mutational analysis of white spruce (Picea glauca) ent-kaurene synthase (PgKS) reveals common and distinct mechanisms of conifer diterpene synthases of general and specialized metabolism. Phytochemistry. 2012 Feb; 74(?):30-9. doi: 10.1016/j.phytochem.2011.11.004. [PMID: 22177479]
  • Matthew R Siebert, Jiaxu Zhang, Srirangam V Addepalli, Dean J Tantillo, William L Hase. The need for enzymatic steering in abietic acid biosynthesis: gas-phase chemical dynamics simulations of carbocation rearrangements on a bifurcating potential energy surface. Journal of the American Chemical Society. 2011 Jun; 133(21):8335-43. doi: 10.1021/ja201730y. [PMID: 21548620]
  • Dana Morrone, Matthew L Hillwig, Matthew E Mead, Luke Lowry, D Bruce Fulton, Reuben J Peters. Evident and latent plasticity across the rice diterpene synthase family with potential implications for the evolution of diterpenoid metabolism in the cereals. The Biochemical journal. 2011 May; 435(3):589-95. doi: 10.1042/bj20101429. [PMID: 21323642]
  • Reuben J Peters, Ora A Carter, Yan Zhang, Brian W Matthews, Rodney B Croteau. Bifunctional abietadiene synthase: mutual structural dependence of the active sites for protonation-initiated and ionization-initiated cyclizations. Biochemistry. 2003 Mar; 42(9):2700-7. doi: 10.1021/bi020492n. [PMID: 12614165]
  • Matthew M Ravn, Reuben J Peters, Robert M Coates, Rodney Croteau. Mechanism of abietadiene synthase catalysis: stereochemistry and stabilization of the cryptic pimarenyl carbocation intermediates. Journal of the American Chemical Society. 2002 Jun; 124(24):6998-7006. doi: 10.1021/ja017734b. [PMID: 12059223]