4,4-Diisothiocyanostilbene-2,2-disulfonate (BioDeep_00000898499)
代谢物信息卡片
4,4-Diisothiocyanostilbene-2,2-disulfonate
化学式: C16H8N2O6S4-2 (451.9265228)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=C(C=C1N=C=S)S(=O)(=O)[O-])C=CC2=C(C=C(C=C2)N=C=S)S(=O)(=O)[O-]
InChI: InChI=1S/C16H10N2O6S4/c19-27(20,21)15-7-13(17-9-25)5-3-11(15)1-2-12-4-6-14(18-10-26)8-16(12)28(22,23)24/h1-8H,(H,19,20,21)(H,22,23,24)/p-2/b2-1+
数据库引用编号
3 个数据库交叉引用编号
- PubChem: 6146472
- ChEMBL: CHEMBL133930
- MeSH: 4,4-Diisothiocyanostilbene-2,2-Disulfonic Acid
分类词条
相关代谢途径
Reactome(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
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10.2478/s11658-007-0019-9. [PMID: 17457523] - Valentina Benfenati, Grazia Paola Nicchia, Maria Svelto, Carmela Rapisarda, Antonio Frigeri, Stefano Ferroni. Functional down-regulation of volume-regulated anion channels in AQP4 knockdown cultured rat cortical astrocytes.
Journal of neurochemistry.
2007 Jan; 100(1):87-104. doi:
10.1111/j.1471-4159.2006.04164.x. [PMID: 17064359] - Julia E Raftos, Stephney Whillier, Bogdan E Chapman, Philip W Kuchel. Kinetics of uptake and deacetylation of N-acetylcysteine by human erythrocytes.
The international journal of biochemistry & cell biology.
2007; 39(9):1698-706. doi:
10.1016/j.biocel.2007.04.014. [PMID: 17544838] - L Bernucci, M Henríquez, P Díaz, G Riquelme. Diverse calcium channel types are present in the human placental syncytiotrophoblast basal membrane.
Placenta.
2006 Nov; 27(11-12):1082-95. doi:
10.1016/j.placenta.2005.12.007. [PMID: 16564089] - In-Ra Seo, Sang Hyun Moh, Eun Hui Lee, Gerhard Meissner, Do Han Kim. Aldolase potentiates DIDS activation of the ryanodine receptor in rabbit skeletal sarcoplasmic reticulum.
The Biochemical journal.
2006 Oct; 399(2):325-33. doi:
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American journal of physiology. Cell physiology.
2006 Oct; 291(4):C788-801. doi:
10.1152/ajpcell.00094.2006. [PMID: 16707554] - Alexander C Whitley, Douglas H Sweet, Thomas Walle. Site-specific accumulation of the cancer preventive dietary polyphenol ellagic acid in epithelial cells of the aerodigestive tract.
The Journal of pharmacy and pharmacology.
2006 Sep; 58(9):1201-9. doi:
10.1211/jpp.58.9.0006. [PMID: 16945178] - Felix Knauf, Nilufar Mohebbi, Carsten Teichert, Diana Herold, Blanka Rogina, Stephen Helfand, Maik Gollasch, Friedrich C Luft, Peter S Aronson. The life-extending gene Indy encodes an exchanger for Krebs-cycle intermediates.
The Biochemical journal.
2006 Jul; 397(1):25-9. doi:
10.1042/bj20060409. [PMID: 16608441] - Fukashi Ishibashi. Chronic high glucose inhibits albumin reabsorption by lysosomal alkalinization in cultured porcine proximal tubular epithelial cells (LLC-PK1).
Diabetes research and clinical practice.
2006 Jun; 72(3):223-30. doi:
10.1016/j.diabres.2005.10.019. [PMID: 16313995] - Rossella Elisei, Agnese Vivaldi, Raffaele Ciampi, Pinuccia Faviana, Fulvio Basolo, Ferruccio Santini, Claudio Traino, Furio Pacini, Aldo Pinchera. Treatment with drugs able to reduce iodine efflux significantly increases the intracellular retention time in thyroid cancer cells stably transfected with sodium iodide symporter complementary deoxyribonucleic acid.
The Journal of clinical endocrinology and metabolism.
2006 Jun; 91(6):2389-95. doi:
10.1210/jc.2005-2480. [PMID: 16537683] - Weifeng Song, Siriporn C Chattipakorn, Lori L McMahon. Glycine-gated chloride channels depress synaptic transmission in rat hippocampus.
Journal of neurophysiology.
2006 Apr; 95(4):2366-79. doi:
10.1152/jn.00386.2005. [PMID: 16381810] - Roger J Thompson, Hillary C S R Akana, Claire Finnigan, Kathryn E Howell, John H Caldwell. Anion channels transport ATP into the Golgi lumen.
American journal of physiology. Cell physiology.
2006 Feb; 290(2):C499-514. doi:
10.1152/ajpcell.00585.2004. [PMID: 16403948] - Yvonne Neye, Martina Düfer, Gisela Drews, Peter Krippeit-Drews. HIV protease inhibitors: suppression of insulin secretion by inhibition of voltage-dependent K+ currents and anion currents.
The Journal of pharmacology and experimental therapeutics.
2006 Jan; 316(1):106-12. doi:
10.1124/jpet.105.090589. [PMID: 16162820] - Astrid Stumpf, Joana Almaca, Karl Kunzelmann, Kerstin Wenners-Epping, Stephan M Huber, Johannes Haberle, Sabine Falk, Angelika Duebbers, Mike Walte, Hans Oberleithner, Hermann Schillers. IADS, a decomposition product of DIDS activates a cation conductance in Xenopus oocytes and human erythrocytes: new compound for the diagnosis of cystic fibrosis.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.
2006; 18(4-5):243-52. doi:
10.1159/000097671. [PMID: 17167229] - Takashi Araki, Matsuhiko Hayashi, Takao Saruta. Anion-exchange blocker enhances cytoplasmic vacuole formation and cell death in serum-deprived mouse kidney epithelial cells in mice.
Cell biology international.
2006 Jan; 30(1):93-100. doi:
10.1016/j.cellbi.2005.10.020. [PMID: 16376114] - Min Xia, Mengjun Hou, Huilian Zhu, Jing Ma, Zhihong Tang, Qing Wang, Yan Li, Dongsheng Chi, Xiaoping Yu, Ting Zhao, Pinghua Han, Xiaodong Xia, Wenhua Ling. Anthocyanins induce cholesterol efflux from mouse peritoneal macrophages: the role of the peroxisome proliferator-activated receptor {gamma}-liver X receptor {alpha}-ABCA1 pathway.
The Journal of biological chemistry.
2005 Nov; 280(44):36792-801. doi:
10.1074/jbc.m505047200. [PMID: 16107338] - Kimberly Matulef, Merritt Maduke. Side-dependent inhibition of a prokaryotic ClC by DIDS.
Biophysical journal.
2005 Sep; 89(3):1721-30. doi:
10.1529/biophysj.105.066522. [PMID: 15994902] - Sachar Lambert, Johannes Oberwinkler. Characterization of a proton-activated, outwardly rectifying anion channel.
The Journal of physiology.
2005 Aug; 567(Pt 1):191-213. doi:
10.1113/jphysiol.2005.089888. [PMID: 15961423] - David Pérez-Morga, Benoit Vanhollebeke, Françoise Paturiaux-Hanocq, Derek P Nolan, Laurence Lins, Fabrice Homblé, Luc Vanhamme, Patricia Tebabi, Annette Pays, Philippe Poelvoorde, Alain Jacquet, Robert Brasseur, Etienne Pays. Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes.
Science (New York, N.Y.).
2005 Jul; 309(5733):469-72. doi:
10.1126/science.1114566. [PMID: 16020735] - Pauline Cavelier, David Attwell. Tonic release of glutamate by a DIDS-sensitive mechanism in rat hippocampal slices.
The Journal of physiology.
2005 Apr; 564(Pt 2):397-410. doi:
10.1113/jphysiol.2004.082131. [PMID: 15695241] - Solange Abdulnour-Nakhoul, Nazih L Nakhoul, Scott A Wheeler, Paul Wang, Eric R Swenson, Roy C Orlando. HCO3- secretion in the esophageal submucosal glands.
American journal of physiology. Gastrointestinal and liver physiology.
2005 Apr; 288(4):G736-44. doi:
10.1152/ajpgi.00055.2004. [PMID: 15576627] - Marie Vanková, Vladimir A Snetkov, Greg A Knock, Philip I Aaronson, Jeremy P T Ward. Euhydric hypercapnia increases vasoreactivity of rat pulmonary arteries via HCO3- transport and depolarisation.
Cardiovascular research.
2005 Feb; 65(2):505-12. doi:
10.1016/j.cardiores.2004.10.038. [PMID: 15639490] - Wen-Zhi Lan, Houria Abbas, Hung D Lam, Anne-Marie Lemay, Ceredwyn E Hill. Contribution of a time-dependent and hyperpolarization-activated chloride conductance to currents of resting and hypotonically shocked rat hepatocytes.
American journal of physiology. Gastrointestinal and liver physiology.
2005 Feb; 288(2):G221-9. doi:
10.1152/ajpgi.00226.2004. [PMID: 15358597] - Florian Nolte, Oliver Friedrich, Markus Rojewski, Rainer H A Fink, Hubert Schrezenmeier, Sixten Körper. Depolarisation of the plasma membrane in the arsenic trioxide (As2O3)-and anti-CD95-induced apoptosis in myeloid cells.
FEBS letters.
2004 Dec; 578(1-2):85-9. doi:
10.1016/j.febslet.2004.10.075. [PMID: 15581621] - Byung-Hyun Park, Young Lee, Marlei Walton, Laurence Duplomb, Roger H Unger. Demonstration of reverse fatty acid transport from rat cardiomyocytes.
Journal of lipid research.
2004 Nov; 45(11):1992-9. doi:
10.1194/jlr.m400237-jlr200. [PMID: 15342682] - Philip A Knauf, Foon-Yee Law, Tze-Wah Vivian Leung, Stephen J Atherton. Relocation of the disulfonic stilbene sites of AE1 (band 3) on the basis of fluorescence energy transfer measurements.
Biochemistry.
2004 Sep; 43(38):11917-31. doi:
10.1021/bi048622a. [PMID: 15379532] - J M Kristensen, M Kristensen, C Juel. Expression of Na+/HCO3- co-transporter proteins (NBCs) in rat and human skeletal muscle.
Acta physiologica Scandinavica.
2004 Sep; 182(1):69-76. doi:
10.1111/j.1365-201x.2004.01297.x. [PMID: 15329059] - P Settle, K Mynett, P Speake, E Champion, I M Doughty, C P Sibley, S W D'Souza, J Glazier. Polarized lactate transporter activity and expression in the syncytiotrophoblast of the term human placenta.
Placenta.
2004 Jul; 25(6):496-504. doi:
10.1016/j.placenta.2003.11.009. [PMID: 15135232] - Xiao-Gai Yang, Xiao-Da Yang, Lan Yuan, Kui Wang, Debbie C Crans. The permeability and cytotoxicity of insulin-mimetic vanadium compounds.
Pharmaceutical research.
2004 Jun; 21(6):1026-33. doi:
10.1023/b:pham.0000029293.89113.d5. [PMID: 15212169] - Alessandra Picollo, Antonella Liantonio, Maria Paola Didonna, Laura Elia, Diana Conte Camerino, Michael Pusch. Molecular determinants of differential pore blocking of kidney CLC-K chloride channels.
EMBO reports.
2004 Jun; 5(6):584-9. doi:
10.1038/sj.embor.7400169. [PMID: 15167890] - Ling Wei, Ai Ying Xiao, Chun Jin, Aizhen Yang, Zhong Yang Lu, Shan Ping Yu. Effects of chloride and potassium channel blockers on apoptotic cell shrinkage and apoptosis in cortical neurons.
Pflugers Archiv : European journal of physiology.
2004 Jun; 448(3):325-34. doi:
10.1007/s00424-004-1277-2. [PMID: 15057559] - K M Gilmour, P R Desforges, S F Perry. Buffering limits plasma HCO3- dehydration when red blood cell anion exchange is inhibited.
Respiratory physiology & neurobiology.
2004 May; 140(2):173-87. doi:
10.1016/j.resp.2004.02.001. [PMID: 15134665] - Jeppe Praetorius, Young-Hee Kim, Elena V Bouzinova, Sebastian Frische, Aleksandra Rojek, Christian Aalkjaer, Søren Nielsen. NBCn1 is a basolateral Na+-HCO3- cotransporter in rat kidney inner medullary collecting ducts.
American journal of physiology. Renal physiology.
2004 May; 286(5):F903-12. doi:
10.1152/ajprenal.00437.2002. [PMID: 15075186] - Wen-Hao Zhang, N Alan Walker, John W Patrick, Stephen D Tyerman. Pulsing Cl- channels in coat cells of developing bean seeds linked to hypo-osmotic turgor regulation.
Journal of experimental botany.
2004 May; 55(399):993-1001. doi:
10.1093/jxb/erh120. [PMID: 15047765] - Ha-Van Nguyen, Alan Stuart-Tilley, Seth L Alper, James E Melvin. Cl(-)/HCO(3)(-) exchange is acetazolamide sensitive and activated by a muscarinic receptor-induced [Ca(2+)](i) increase in salivary acinar cells.
American journal of physiology. Gastrointestinal and liver physiology.
2004 Feb; 286(2):G312-20. doi:
10.1152/ajpgi.00158.2003. [PMID: 12958022]