Carminomycin(1+) (BioDeep_00000898497)
代谢物信息卡片
化学式: C26H28NO10+ (514.1713)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)O)O)(C(=O)C)O)[NH3+])O
InChI: InChI=1S/C26H27NO10/c1-9-21(30)13(27)6-16(36-9)37-15-8-26(35,10(2)28)7-12-18(15)25(34)20-19(23(12)32)22(31)11-4-3-5-14(29)17(11)24(20)33/h3-5,9,13,15-16,21,29-30,32,34-35H,6-8,27H2,1-2H3/p+1/t9-,13-,15-,16-,21+,26-/m0/s1
描述信息
An anthracyline cation that is the conjugate acid of carminomycin, obtained by protonation of the amino group.
D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059005 - Topoisomerase II Inhibitors
D004791 - Enzyme Inhibitors
同义名列表
1 个代谢物同义名
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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INOH(0)
PlantCyc(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- N G Prokof'eva, M M Anisimov, M I Kiseleva, N M Rebachuk, N D Pokhilo. [Cytotoxic activity of dammarane triterpenoids from birch leaves].
Izvestiia Akademii nauk. Seriia biologicheskaia.
2002 Nov; ?(6):645-9. doi:
". [PMID: 12561324] - Y Sato, L Eddy, P Hochstein. Comparative cardiotoxicity of doxorubicin and a morpholino anthracycline derivative (KRN8602).
Biochemical pharmacology.
1991 Nov; 42(12):2283-7. doi:
10.1016/0006-2952(91)90231-s. [PMID: 1764113] - Sh S Tazhibaev, E G Lenskaia, N R Alekseeva, Zh S Sisemalieva, B V Monakhov. [The influence on tumor growth and the function of the thiol-dependent systems of the liver of excess cooking fat and vitamin E in the diet. The effects of carminomycin].
Voprosy pitaniia.
1990 May; ?(3):47-51. doi:
". [PMID: 2399682] - P P Constantinides, Y Y Wang, T G Burke, T R Tritton. Transverse location of anthracyclines in lipid bilayers. Paramagnetic quenching studies.
Biophysical chemistry.
1990 Apr; 35(2-3):259-64. doi:
10.1016/0301-4622(90)80013-w. [PMID: 2168766] - J Kuratsu, Y Mihara, M Kochi, S Takaki, Y Ushio. [Antitumor effect of a new anthracycline derivative, MX2, against human glioma cells].
Gan to kagaku ryoho. Cancer & chemotherapy.
1989 Mar; 16(3 Pt 1):399-403. doi:
. [PMID: 2930204] - Sh S Tazhibaev, E G Lenskaia, K Kh Khasenova, N M Karsybekova, N R Alekseeva. [Effect of carminomycin on the enzyme systems of the metabolism of active forms of oxygen and on free-radical lipid oxidation in August rats with Walker carcinosarcoma 256].
Eksperimental'naia onkologiia.
1989; 11(4):66-70. doi:
". [PMID: 2759014] - S Izumoto, N Arita, Y Ushio, T Hayakawa, T Ohnishi, T Taki, H Yamamoto, Y Oku, H Mogami, N Komeshima. [Effect of MX-2, a morpholino anthracycline derivative, against human and rat glioma cells and experimental leptomeningeal tumors in rats].
Gan to kagaku ryoho. Cancer & chemotherapy.
1988 May; 15(5):1765-9. doi:
. [PMID: 3369870] - A I Suslova, I A Gorskaia, I D Sheveleva, T V Kaverinskaia, L M Tsofina. [Relation between respiration and swelling of liver mitochondria induced by anthracycline antibiotics].
Biokhimiia (Moscow, Russia).
1988 Feb; 53(2):227-32. doi:
. [PMID: 3163503] - T G Burke, T R Tritton. Ligand self-association at the surface of liposomes: a complication during equilibrium-binding studies.
Analytical biochemistry.
1984 Nov; 143(1):135-40. doi:
10.1016/0003-2697(84)90567-0. [PMID: 6597683] - N P Chuchalina, E D Gol'dberg, B Iu Sal'nik, V A Telesheva. [Role of the adrenal glands in the cytostatic action mechanism of antitumor antibiotics].
Antibiotiki.
1978 Apr; 23(4):362-5. doi:
NULL. [PMID: 646337] - M E Wall, M C Wani, H Taylor. Isolation and chemical characterization of antitumor agents from plants.
Cancer treatment reports.
1976 Aug; 60(8):1011-30. doi:
". [PMID: 991155] - O A Lapchinskaya, T A Saburova, V I Ponomarenko. Production of carminomycin by auxotrophic mutants of Actinomadura carminata.
Zeitschrift fur allgemeine Mikrobiologie.
1975; 15(5):383-5. doi:
". [PMID: 1189475]
