PYRIDINE-2,6-dicarboxylate (BioDeep_00000898317)
代谢物信息卡片
化学式: C7H3NO4-2 (165.0062)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=NC(=C1)C(=O)[O-])C(=O)[O-]
InChI: InChI=1S/C7H5NO4/c9-6(10)4-2-1-3-5(8-4)7(11)12/h1-3H,(H,9,10)(H,11,12)/p-2
描述信息
D064449 - Sequestering Agents > D002614 - Chelating Agents
D004791 - Enzyme Inhibitors
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(4)
PlantCyc(0)
代谢反应
4 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(4)
- Metabolism and regulation:
ATP + CoA + propionate ⟶ AMP + PPi + PROP-CoA
- Amino acid metabolism:
ATP + CoA + propionate ⟶ AMP + PPi + PROP-CoA
- Amino acid biosynthesis:
ATP + CoA + propionate ⟶ AMP + PPi + PROP-CoA
- Lysine biosynthesis II:
H2O + N-acetyl-L,L-2,6-diaminopimelate ⟶ CH3COO- + L,L-diaminopimelate
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Su-Yan Wang, Yi-Bo Pang, Yuan Tao, Xin-Chi Shi, Zhang Yun-Jiao, Yan-Xia Wang, Jiang Yong-Hui, Xin-Yu Ji, Bing-Lin Wang, Daniela D Herrera-Balandrano, Pedro Laborda. Dipicolinic acid enhances kiwifruit resistance to Botrytis cinerea by promoting phenolics accumulation.
Pest management science.
2023 Apr; ?(?):. doi:
10.1002/ps.7496
. [PMID: 37024430] - Ting Wang, Kaiju Xu, Liyun Zhao, Rongsheng Tong, Liang Xiong, Jianyou Shi. Recent research and development of NDM-1 inhibitors.
European journal of medicinal chemistry.
2021 Nov; 223(?):113667. doi:
10.1016/j.ejmech.2021.113667
. [PMID: 34225181] - Xiaoqing Li, Junjun Luo, Xingxing Jiang, Minghui Yang, Avraham Rasooly. Gold nanocluster-europium(III) ratiometric fluorescence assay for dipicolinic acid.
Mikrochimica acta.
2021 01; 188(1):26. doi:
10.1007/s00604-020-04667-z
. [PMID: 33404771] - Chen-Xi Zhao, Xiao-Ping Zhang, Yang Shu, Jian-Hua Wang. Europium-Pyridinedicarboxylate-Adenine Light-Up Fluorescence Nanoprobes for Selective Detection of Phosphate in Biological Fluids.
ACS applied materials & interfaces.
2020 May; 12(20):22593-22600. doi:
10.1021/acsami.0c04318
. [PMID: 32345010] - Yongquan Luo, Lei Zhang, Lingyi Zhang, Bohao Yu, Yajie Wang, Weibing Zhang. Multiporous Terbium Phosphonate Coordination Polymer Microspheres as Fluorescent Probes for Trace Anthrax Biomarker Detection.
ACS applied materials & interfaces.
2019 May; 11(17):15998-16005. doi:
10.1021/acsami.9b01123
. [PMID: 30951283] - Kanmani Anandan, Ravishankar Rai Vittal. Endophytic Paenibacillus amylolyticus KMCLE06 Extracted Dipicolinic Acid as Antibacterial Agent Derived via Dipicolinic Acid Synthetase Gene.
Current microbiology.
2019 Feb; 76(2):178-186. doi:
10.1007/s00284-018-1605-y
. [PMID: 30498942] - Debanjana Biswal, Nikhil Ranjan Pramanik, Syamal Chakrabarti, Michael G B Drew, Krishnendu Acharya, Swarnendu Chandra. Syntheses, crystal structures, DFT calculations, protein interaction and anticancer activities of water soluble dipicolinic acid-imidazole based oxidovanadium(iv) complexes.
Dalton transactions (Cambridge, England : 2003).
2017 Dec; 46(47):16682-16702. doi:
10.1039/c7dt02903a
. [PMID: 29168865] - Keying Cai, Mulan Zeng, Fenfen Liu, Nan Liu, Zhenzhong Huang, Yonghai Song, Li Wang. BSA-AuNPs@Tb-AMP metal-organic frameworks for ratiometric fluorescence detection of DPA and Hg2.
Luminescence : the journal of biological and chemical luminescence.
2017 Nov; 32(7):1277-1282. doi:
10.1002/bio.3321
. [PMID: 28569414] - Peter Setlow, Shiwei Wang, Yong-Qing Li. Germination of Spores of the Orders Bacillales and Clostridiales.
Annual review of microbiology.
2017 09; 71(?):459-477. doi:
10.1146/annurev-micro-090816-093558
. [PMID: 28697670] - Marat R Sadykov, Jong-Sam Ahn, Todd J Widhelm, Valerie M Eckrich, Jennifer L Endres, Adam Driks, Gregory E Rutkowski, Kevin L Wingerd, Kenneth W Bayles. Poly(3-hydroxybutyrate) fuels the tricarboxylic acid cycle and de novo lipid biosynthesis during Bacillus anthracis sporulation.
Molecular microbiology.
2017 Jun; 104(5):793-803. doi:
10.1111/mmi.13665
. [PMID: 28299860] - Shiwei Wang, Christopher J Doona, Peter Setlow, Yong-Qing Li. Use of Raman Spectroscopy and Phase-Contrast Microscopy To Characterize Cold Atmospheric Plasma Inactivation of Individual Bacterial Spores.
Applied and environmental microbiology.
2016 10; 82(19):5775-84. doi:
10.1128/aem.01669-16
. [PMID: 27422840] - Sofia Nestora, Franck Merlier, Elise Prost, Karsten Haupt, Claire Rossi, Bernadette Tse Sum Bui. Solid-phase extraction of betanin and isobetanin from beetroot extracts using a dipicolinic acid molecularly imprinted polymer.
Journal of chromatography. A.
2016 Sep; 1465(?):47-54. doi:
10.1016/j.chroma.2016.08.069
. [PMID: 27592611] - Mesay Mulugeta Wolle, Timothy Fahrenholz, G M Mizanur Rahman, Matt Pamuku, H M 'Skip' Kingston, Damien Browne. Method development for the redox speciation analysis of iron by ion chromatography-inductively coupled plasma mass spectrometry and carryover assessment using isotopically labeled analyte analogues.
Journal of chromatography. A.
2014 Jun; 1347(?):96-103. doi:
10.1016/j.chroma.2014.04.066
. [PMID: 24819017] - Audra G Sostarecz, Ernestas Gaidamauskas, Steve Distin, Sandra J Bonetti, Nancy E Levinger, Debbie C Crans. Correlation of insulin-enhancing properties of vanadium-dipicolinate complexes in model membrane systems: phospholipid langmuir monolayers and AOT reverse micelles.
Chemistry (Weinheim an der Bergstrasse, Germany).
2014 Apr; 20(17):5149-59. doi:
10.1002/chem.201201803
. [PMID: 24615733] - Elise Dumont, Guillaume Pompidor, Anthony D'Aléo, Jean Vicat, Loïc Toupet, Richard Kahn, Eric Girard, Olivier Maury, Nicolas Giraud. Exploration of the supramolecular interactions involving tris-dipicolinate lanthanide complexes in protein crystals by a combined biostructural, computational and NMR study.
Physical chemistry chemical physics : PCCP.
2013 Nov; 15(41):18235-42. doi:
10.1039/c3cp53671h
. [PMID: 24064912] - Sameena Mehtab, Gisela Gonçalves, Somnath Roy, Ana Isabel Tomaz, Teresa Santos-Silva, Marino F A Santos, Maria J Romão, Tamás Jakusch, Tamás Kiss, João Costa Pessoa. Interaction of vanadium(IV) with human serum apo-transferrin.
Journal of inorganic biochemistry.
2013 Apr; 121(?):187-95. doi:
10.1016/j.jinorgbio.2012.12.020
. [PMID: 23411030] - Letícia Christina Pires Gonçalves, Sandra Maria Da Silva, Paul C DeRose, Rômulo Augusto Ando, Erick Leite Bastos. Beetroot-pigment-derived colorimetric sensor for detection of calcium dipicolinate in bacterial spores.
PloS one.
2013; 8(9):e73701. doi:
10.1371/journal.pone.0073701
. [PMID: 24019934] - S Roth, J Feichtinger, C Hertel. Characterization of Bacillus subtilis spore inactivation in low-pressure, low-temperature gas plasma sterilization processes.
Journal of applied microbiology.
2010 Feb; 108(2):521-31. doi:
10.1111/j.1365-2672.2009.04453.x
. [PMID: 19659696] - Nejat Düzgüneş, Henrique Faneca, Maria C Lima. Methods to monitor liposome fusion, permeability, and interaction with cells.
Methods in molecular biology (Clifton, N.J.).
2010; 606(?):209-32. doi:
10.1007/978-1-60761-447-0_16
. [PMID: 20013400] - Ming Li, Wenjun Ding, Jason J Smee, Bharat Baruah, Gail R Willsky, Debbie C Crans. Anti-diabetic effects of vanadium(III, IV, V)-chlorodipicolinate complexes in streptozotocin-induced diabetic rats.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine.
2009 Dec; 22(6):895-905. doi:
10.1007/s10534-009-9241-4
. [PMID: 19404749] - James Gardiner, Anita V Thomae, Raveendra I Mathad, Dieter Seebach, Stefanie D Krämer. Comparison of permeation through phosphatidylcholine bilayers of N-dipicolinyl-alpha- and -beta-oligopeptides.
Chemistry & biodiversity.
2006 Nov; 3(11):1181-201. doi:
10.1002/cbdv.200690120
. [PMID: 17193232] - Nobuko Watanabe, Maki Hattori, Eiji Yokoyama, Shigeki Isomura, Minoru Ujita, Akira Hara. Entomogenous fungi that produce 2,6-pyridine dicarboxylic acid (dipicolinic acid).
Journal of bioscience and bioengineering.
2006 Oct; 102(4):365-8. doi:
10.1263/jbb.102.365
. [PMID: 17116586] - Debbie C Crans, Bharat Baruah, Nancy E Levinger. Oxovanadates: a novel probe for studying lipid-water interfaces.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2006 May; 60(4):174-81. doi:
10.1016/j.biopha.2006.02.006
. [PMID: 16600566] - Fumitaka Kawai, Hiroshi Hara, Hiromu Takamatsu, Kazuhito Watabe, Kouji Matsumoto. Cardiolipin enrichment in spore membranes and its involvement in germination of Bacillus subtilis Marburg.
Genes & genetic systems.
2006 Apr; 81(2):69-76. doi:
10.1266/ggs.81.69
. [PMID: 16755131] - Anita V Thomae, Heidi Wunderli-Allenspach, Stefanie D Krämer. Permeation of aromatic carboxylic acids across lipid bilayers: the pH-partition hypothesis revisited.
Biophysical journal.
2005 Sep; 89(3):1802-11. doi:
10.1529/biophysj.105.060871
. [PMID: 15951388] - Péter Buglyó, Debbie C Crans, Eszter M Nagy, Ruby Lisa Lindo, Luqin Yang, Jason J Smee, Wenzheng Jin, Lai-Har Chi, Michael E Godzala Iii, Gail R Willsky. Aqueous chemistry of the vanadium(III) (V(III)) and the V(III)-dipicolinate systems and a comparison of the effect of three oxidation states of vanadium compounds on diabetic hyperglycemia in rats.
Inorganic chemistry.
2005 Jul; 44(15):5416-27. doi:
10.1021/ic048331q
. [PMID: 16022540] - Keiko Murakami, Yasuko Tanemura, Masataka Yoshino. Dipicolinic acid prevents the copper-dependent oxidation of low density lipoprotein.
The Journal of nutritional biochemistry.
2003 Feb; 14(2):99-103. doi:
10.1016/s0955-2863(02)00252-8
. [PMID: 12667601] - Z J Ma, M Yamaguchi. Stimulatory effect of zinc on deoxyribonucleic acid synthesis in bone growth of newborn rats: enhancement with zinc and insulin-like growth factor-I.
Calcified tissue international.
2001 Sep; 69(3):158-63. doi:
10.1007/s00223-001-2010-1
. [PMID: 11683530] - J M Rausch, W C Wimley. A high-throughput screen for identifying transmembrane pore-forming peptides.
Analytical biochemistry.
2001 Jun; 293(2):258-63. doi:
10.1006/abio.2001.5137
. [PMID: 11399041] - P D Thackray, J Behravan, T W Southworth, A Moir. GerN, an antiporter homologue important in germination of Bacillus cereus endospores.
Journal of bacteriology.
2001 Jan; 183(2):476-82. doi:
10.1128/jb.183.2.476-482.2001
. [PMID: 11133940] - Z Chen, C Tang, J Xu. Non-suppressed conductivity and indirect UV detection of carboxylic acids in environmental samples by ion-exclusion chromatography using 2,6-pyridinedicarboxylic acidic eluent.
Journal of chromatography. A.
1999 Oct; 859(2):173-81. doi:
10.1016/s0021-9673(99)00885-7
. [PMID: 10574210] - J E Jackman, C R Raetz, C A Fierke. UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase of Escherichia coli is a zinc metalloenzyme.
Biochemistry.
1999 Feb; 38(6):1902-11. doi:
10.1021/bi982339s
. [PMID: 10026271] - A Tricerri, B Córsico, J D Toledo, H A Garda, R R Brenner. Conformation of apolipoprotein AI in reconstituted lipoprotein particles and particle-membrane interaction: effect of cholesterol.
Biochimica et biophysica acta.
1998 Mar; 1391(1):67-78. doi:
10.1016/s0005-2760(97)00187-2
. [PMID: 9518555] - S Vincenzetti, A Cambi, E Balducci, P Natalini, R Volpini, A Vita. Human placenta cytidine deaminase: a zinc metalloprotein.
Biochemistry and molecular biology international.
1997 Jul; 42(3):469-76. doi:
10.1080/15216549700202871
. [PMID: 9247704] - W A Talbot, L X Zheng, B R Lentz. Acyl chain unsaturation and vesicle curvature alter outer leaflet packing and promote poly(ethylene glycol)-mediated membrane fusion.
Biochemistry.
1997 May; 36(19):5827-36. doi:
10.1021/bi962437i
. [PMID: 9153423] - M Yamaguchi, Y Ehara. Zinc decrease and bone metabolism in the femoral-metaphyseal tissues of rats with skeletal unloading.
Calcified tissue international.
1995 Sep; 57(3):218-23. doi:
10.1007/bf00310262
. [PMID: 8574940] - J B Lamture, T G Wensel. Intensely luminescent immunoreactive conjugates of proteins and dipicolinate-based polymeric Tb (III) chelates.
Bioconjugate chemistry.
1995 Jan; 6(1):88-92. doi:
10.1021/bc00031a010
. [PMID: 7711110] - A R Viguera, M Mencía, F M Goñi. Time-resolved and equilibrium measurements of the effects of poly(ethylene glycol) on small unilamellar phospholipid vesicles.
Biochemistry.
1993 Apr; 32(14):3708-13. doi:
10.1021/bi00065a024
. [PMID: 8466910] - W Ma, K J Hwang, V H Lee. A fluorescence quenching method for estimating chelating groups in chelate-conjugated macromolecules.
Pharmaceutical research.
1993 Feb; 10(2):204-7. doi:
10.1023/a:1018974424624
. [PMID: 8456066] - K Nam, S Kimura, H Fujiki, Y Imanishi. Effects of phorbol ester and teleocidin on Ca2+-induced fusion of liposomes.
Biochemical and biophysical research communications.
1989 Dec; 165(3):1256-61. doi:
10.1016/0006-291x(89)92737-x
. [PMID: 2610691] - M Yamaguchi, R Matsui. Effect of dipicolinate, a chelator of zinc, on bone protein synthesis in tissue culture. The essential role of zinc.
Biochemical pharmacology.
1989 Dec; 38(24):4485-9. doi:
10.1016/0006-2952(89)90660-6
. [PMID: 2604749] - L Corazzi, G Fratto, R Pistolesi, G Arienti. Fusion of liposomes and rat brain microsomes examined by two assays.
The Journal of membrane biology.
1989 Dec; 112(2):123-9. doi:
10.1007/bf01871273
. [PMID: 2621744] - R Nagaraj, M Joseph, G L Reddy. Perturbation of the lipid bilayer of model membranes by synthetic signal peptides.
Biochimica et biophysica acta.
1987 Oct; 903(3):465-72. doi:
10.1016/0005-2736(87)90053-8
. [PMID: 3311164] - M Bental, J Wilschut, J Scholma, S Nir. Ca2+-induced fusion of large unilamellar phosphatidylserine/cholesterol vesicles.
Biochimica et biophysica acta.
1987 Apr; 898(2):239-47. doi:
10.1016/0005-2736(87)90043-5
. [PMID: 3828344] - I Krieger, R Cash, G W Evans. Picolinic acid in acrodermatitis enteropathica: evidence for a disorder of tryptophan metabolism.
Journal of pediatric gastroenterology and nutrition.
1984; 3(1):62-8. doi:
10.1097/00005176-198401000-00014
. [PMID: 6694049] - W T Johnson, G W Evans. Tissue uptake of zinc in rats following the administration of zinc dipicolinate or zinc histidinate.
The Journal of nutrition.
1982 May; 112(5):914-9. doi:
10.1093/jn/112.5.914
. [PMID: 7077422] - G W Evans, E C Johnson. Zinc concentration of liver and kidneys from rat pups nursing dams fed supplemented zinc dipicolinate or zinc acetate.
The Journal of nutrition.
1980 Oct; 110(10):2121-4. doi:
10.1093/jn/110.10.2121
. [PMID: 7420212] - I E YOUNG. CHARACTERISTICS OF AN ABORTIVELY DISPORIC VARIANT OF BACILLUS CEREUS.
Journal of bacteriology.
1964 Jul; 88(?):242-54. doi:
10.1128/jb.88.1.242-254.1964
. [PMID: 14197894] - J F POWELL, R E STRANGE. Synthesis of dipicolinic acid from 2,6-diketopimelic acid.
Nature.
1959 Sep; 184(?):878-80. doi:
10.1038/184878a0
. [PMID: 14434559]