1-Tuberculosinyladenosine (BioDeep_00000898260)
代谢物信息卡片
化学式: C30H46N5O4+ (540.355)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(lipidsearch) 41.54%
分子结构信息
SMILES: CC1CC=C2C(C1(C)CCC(=CC[N+]3=C(C4=C(N=C3)N(C=N4)C5C(C(C(O5)CO)O)O)N)C)CCCC2(C)C
InChI: InChI=1S/C30H45N5O4/c1-18(10-13-30(5)19(2)8-9-20-21(30)7-6-12-29(20,3)4)11-14-34-16-33-27-23(26(34)31)32-17-35(27)28-25(38)24(37)22(15-36)39-28/h9,11,16-17,19,21-22,24-25,28,31,36-38H,6-8,10,12-15H2,1-5H3/p+1/b18-11+/t19-,21+,22+,24+,25+,28+,30+/m0/s1
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Marwan Ghanem, Jean-Yves Dubé, Joyce Wang, Fiona McIntosh, Daniel Houle, Pilar Domenech, Michael B Reed, Sahadevan Raman, Jeffrey Buter, Adriaan J Minnaard, D Branch Moody, Marcel A Behr. Heterologous Production of 1-Tuberculosinyladenosine in Mycobacterium kansasii Models Pathoevolution towards the Transcellular Lifestyle of Mycobacterium tuberculosis.
mBio.
2020 10; 11(5):. doi:
10.1128/mbio.02645-20. [PMID: 33082253] - Jeffrey Buter, Tan-Yun Cheng, Marwan Ghanem, Anita E Grootemaat, Sahadevan Raman, Xinxin Feng, Ashmir R Plantijn, Thomas Ennis, Joyce Wang, Rachel N Cotton, Emilie Layre, Alexandrea K Ramnarine, Jacob A Mayfield, David C Young, Amanda Jezek Martinot, Noman Siddiqi, Shoko Wakabayashi, Helene Botella, Roger Calderon, Megan Murray, Sabine Ehrt, Barry B Snider, Michael B Reed, Eric Oldfield, Shumin Tan, Eric J Rubin, Marcel A Behr, Nicole N van der Wel, Adriaan J Minnaard, D Branch Moody. Mycobacterium tuberculosis releases an antacid that remodels phagosomes.
Nature chemical biology.
2019 09; 15(9):889-899. doi:
10.1038/s41589-019-0336-0. [PMID: 31427817] - David C Young, Emilie Layre, Shih-Jung Pan, Asa Tapley, John Adamson, Chetan Seshadri, Zhongtao Wu, Jeffrey Buter, Adriaan J Minnaard, Mireia Coscolla, Sebastien Gagneux, Richard Copin, Joel D Ernst, William R Bishai, Barry B Snider, D Branch Moody. In vivo biosynthesis of terpene nucleosides provides unique chemical markers of Mycobacterium tuberculosis infection.
Chemistry & biology.
2015 Apr; 22(4):516-526. doi:
10.1016/j.chembiol.2015.03.015. [PMID: 25910243] - Emilie Layre, Ho Jun Lee, David C Young, Amanda Jezek Martinot, Jeffrey Buter, Adriaan J Minnaard, John W Annand, Sarah M Fortune, Barry B Snider, Isamu Matsunaga, Eric J Rubin, Tom Alber, D Branch Moody. Molecular profiling of Mycobacterium tuberculosis identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378c.
Proceedings of the National Academy of Sciences of the United States of America.
2014 Feb; 111(8):2978-83. doi:
10.1073/pnas.1315883111. [PMID: 24516143]
