3-Hydroxypalmitate (BioDeep_00000898198)
代谢物信息卡片
化学式: C16H31O3- (271.2273)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCCCCCCC(CC(=O)[O-])O
InChI: InChI=1S/C16H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-15(17)14-16(18)19/h15,17H,2-14H2,1H3,(H,18,19)/p-1
描述信息
A 3-hydroxy fatty acid anion that is the conjugate base of 3-hydroxypalmitic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3.
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Yumeto Ujita, Megumi Sakata, Ayaka Yoshihara, Yasufumi Hikichi, Kenji Kai. Signal Production and Response Specificity in the phc Quorum Sensing Systems of Ralstonia solanacearum Species Complex.
ACS chemical biology.
2019 10; 14(10):2243-2251. doi:
10.1021/acschembio.9b00553. [PMID: 31513382] - Myung Hwan Lee, Raees Khan, Weixin Tao, Kihyuck Choi, Seung Yeup Lee, Jae Wook Lee, Eul Chul Hwang, Seon-Woo Lee. Soil metagenome-derived 3-hydroxypalmitic acid methyl ester hydrolases suppress extracellular polysaccharide production in Ralstonia solanacearum.
Journal of biotechnology.
2018 Mar; 270(?):30-38. doi:
10.1016/j.jbiotec.2018.01.023. [PMID: 29407418] - Cristiane Cecatto, Kálita Dos Santos Godoy, Janaína Camacho da Silva, Alexandre Umpierrez Amaral, Moacir Wajner. Disturbance of mitochondrial functions provoked by the major long-chain 3-hydroxylated fatty acids accumulating in MTP and LCHAD deficiencies in skeletal muscle.
Toxicology in vitro : an international journal published in association with BIBRA.
2016 Oct; 36(?):1-9. doi:
10.1016/j.tiv.2016.06.007. [PMID: 27371118] - Cristiane Cecatto, Fernanda H Hickmann, Marília D N Rodrigues, Alexandre U Amaral, Moacir Wajner. Deregulation of mitochondrial functions provoked by long-chain fatty acid accumulating in long-chain 3-hydroxyacyl-CoA dehydrogenase and mitochondrial permeability transition deficiencies in rat heart--mitochondrial permeability transition pore opening as a potential contributing pathomechanism of cardiac alterations in these disorders.
The FEBS journal.
2015 Dec; 282(24):4714-26. doi:
10.1111/febs.13526. [PMID: 26408230] - Kenji Kai, Hideyuki Ohnishi, Mika Shimatani, Shiho Ishikawa, Yuka Mori, Akinori Kiba, Kouhei Ohnishi, Mitsuaki Tabuchi, Yasufumi Hikichi. Methyl 3-Hydroxymyristate, a Diffusible Signal Mediating phc Quorum Sensing in Ralstonia solanacearum.
Chembiochem : a European journal of chemical biology.
2015 Nov; 16(16):2309-18. doi:
10.1002/cbic.201500456. [PMID: 26360813] - G A Achari, R Ramesh. Characterization of bacteria degrading 3-hydroxy palmitic acid methyl ester (3OH-PAME), a quorum sensing molecule of Ralstonia solanacearum.
Letters in applied microbiology.
2015 May; 60(5):447-55. doi:
10.1111/lam.12389. [PMID: 25580768] - Anelise Miotti Tonin, Alexandre Umpierrez Amaral, Estela Natacha Busanello, Juciano Gasparotto, Daniel P Gelain, Niels Gregersen, Moacir Wajner. Mitochondrial bioenergetics deregulation caused by long-chain 3-hydroxy fatty acids accumulating in LCHAD and MTP deficiencies in rat brain: a possible role of mPTP opening as a pathomechanism in these disorders?.
Biochimica et biophysica acta.
2014 Sep; 1842(9):1658-67. doi:
10.1016/j.bbadis.2014.06.011. [PMID: 24946182] - Anelise M Tonin, Mateus Grings, Estela N B Busanello, Alana P Moura, Gustavo C Ferreira, Carolina M Viegas, Carolina G Fernandes, Patrícia F Schuck, Moacir Wajner. Long-chain 3-hydroxy fatty acids accumulating in LCHAD and MTP deficiencies induce oxidative stress in rat brain.
Neurochemistry international.
2010 Jul; 56(8):930-6. doi:
10.1016/j.neuint.2010.03.025. [PMID: 20381565] - David W Johnson, Minh-Uyen Trinh. Analysis of isomeric long-chain hydroxy fatty acids by tandem mass spectrometry: application to the diagnosis of long-chain 3-hydroxyacyl CoA dehydrogenase deficiency.
Rapid communications in mass spectrometry : RCM.
2003; 17(2):171-5. doi:
10.1002/rcm.889. [PMID: 12512097] - R P Garg, W Yindeeyoungyeon, A Gilis, T P Denny, D Van Der Lelie, M A Schell. Evidence that Ralstonia eutropha (Alcaligenes eutrophus) contains a functional homologue of the Ralstonia solanacearum Phc cell density sensing system.
Molecular microbiology.
2000 Oct; 38(2):359-67. doi:
10.1046/j.1365-2958.2000.02131.x. [PMID: 11069661] - A B Flavier, S J Clough, M A Schell, T P Denny. Identification of 3-hydroxypalmitic acid methyl ester as a novel autoregulator controlling virulence in Ralstonia solanacearum.
Molecular microbiology.
1997 Oct; 26(2):251-9. doi:
10.1046/j.1365-2958.1997.5661945.x. [PMID: 9383151] - A Fjellbirkeland, H Kleivdal, C Joergensen, H Thestrup, H B Jensen. Outer membrane proteins of Methylococcus capsulatus (Bath).
Archives of microbiology.
1997 Aug; 168(2):128-35. doi:
10.1007/s002030050478. [PMID: 9238104]
