cis,cis-Muconate (BioDeep_00000898184)
代谢物信息卡片
化学式: C6H4O4-2 (140.0109584)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 56%
分子结构信息
SMILES: C(=CC(=O)[O-])C=CC(=O)[O-]
InChI: InChI=1S/C6H6O4/c7-5(8)3-1-2-4-6(9)10/h1-4H,(H,7,8)(H,9,10)/p-2/b3-1-,4-2-
相关代谢途径
Reactome(0)
BioCyc(6)
PlantCyc(0)
代谢反应
16 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(16)
- superpathway of aromatic compound degradation via 3-oxoadipate:
O2 + catechol ⟶ H+ + HMS
- superpathway of salicylate degradation:
O2 + catechol ⟶ H+ + cis,cis-muconate
- aromatic compounds degradation via β-ketoadipate:
O2 + catechol ⟶ H+ + cis,cis-muconate
- catechol degradation III (ortho-cleavage pathway):
O2 + catechol ⟶ H+ + cis,cis-muconate
- catechol degradation to β-ketoadipate:
O2 + catechol ⟶ H+ + cis,cis-muconate
- mandelate degradation to acetyl-CoA:
O2 + catechol ⟶ H+ + HMS
- catechol degradation to β-ketoadipate:
O2 + catechol ⟶ H+ + cis,cis-muconate
- catechol degradation to β-ketoadipate:
O2 + catechol ⟶ H+ + cis,cis-muconate
- catechol degradation to β-ketoadipate:
O2 + catechol ⟶ H+ + cis,cis-muconate
- aromatic compounds degradation via β-ketoadipate:
O2 + protocatechuate ⟶ 3-carboxy-cis,cis-muconate + H+
- catechol degradation to β-ketoadipate:
O2 + catechol ⟶ H+ + cis,cis-muconate
- catechol degradation III (ortho-cleavage pathway):
O2 + catechol ⟶ H+ + cis,cis-muconate
- superpathway of aromatic compound degradation via 3-oxoadipate:
O2 + trp ⟶ N-formylkynurenine
- catechol degradation to β-ketoadipate:
O2 + catechol ⟶ H+ + cis,cis-muconate
- catechol degradation to β-ketoadipate:
O2 + catechol ⟶ H+ + cis,cis-muconate
- superpathway of aromatic compound degradation:
O2 + protocatechuate ⟶ 3-carboxy-cis,cis-muconate + H+
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Avery C Vilbert, Wayne S Kontur, Derek Gille, Daniel R Noguera, Timothy J Donohue. Engineering Novosphingobium aromaticivorans to produce cis,cis-muconic acid from biomass aromatics.
Applied and environmental microbiology.
2024 Jan; 90(1):e0166023. doi:
10.1128/aem.01660-23
. [PMID: 38117061] - Sepideh Abbaszadeh, Saeed Yousefinejad, Saeed Jafari, Esmaeel Soleimani. In-syringe ionic liquid-dispersive liquid-liquid microextraction coupled with HPLC for the determination of trans,trans-muconic acid in human urine sample.
Journal of separation science.
2021 Aug; 44(16):3126-3136. doi:
10.1002/jssc.202100044
. [PMID: 34114310] - Marcia Domínguez, Juan F Blandez, Beatriz Lozano-Torres, Cristina de la Torre, Maurizio Licchelli, Carlo Mangano, Valeria Amendola, Félix Sancenón, Ramón Martínez-Máñez. A Nanoprobe Based on Gated Mesoporous Silica Nanoparticles for The Selective and Sensitive Detection of Benzene Metabolite t,t-Muconic Acid in Urine.
Chemistry (Weinheim an der Bergstrasse, Germany).
2021 Jan; 27(4):1306-1310. doi:
10.1002/chem.202004272
. [PMID: 33064343] - Sunisa Chaiklieng, Pornnapa Suggaravetsiri, Herman Autrup. Biomatrix of health risk assessment of benzene-exposed workers at Thai gasoline stations.
Journal of occupational health.
2021 Jan; 63(1):e12307. doi:
10.1002/1348-9585.12307
. [PMID: 34957641] - Barbara Rodrigues Geraldino, Rafaella Ferreira Nascimento Nunes, Juliana Barroso Gomes, Isabela Giardini, Paula Vieira Baptista da Silva, Élida Campos, Katia Soares da Poça, Rocio Hassan, Ubirani Barros Otero, Marcia Sarpa. Analysis of Benzene Exposure in Gas Station Workers Using Trans,Trans-Muconic Acid.
International journal of environmental research and public health.
2020 07; 17(15):. doi:
10.3390/ijerph17155295
. [PMID: 32717818] - Luigi De Maria, Caterina Ledda, Antonio Caputi, Francesca Mansi, Enza Sabrina Silvana Cannone, Stefania Sponselli, Domenica Cavone, Francesco Birtolo, Emanuele Cannizzaro, Giovanni Maria Ferri, Venerando Rapisarda, Luigi Vimercati. Biological Monitoring of Exposure to Benzene in Port Workers.
Frontiers in public health.
2020; 8(?):271. doi:
10.3389/fpubh.2020.00271
. [PMID: 32766192] - Sunisa Chaiklieng, Pornnapa Suggaravetsiri, Norbert Kaminski, Herman Autrup. Factors Affecting Urinary tt-Muconic Acid Detection among Benzene Exposed Workers at Gasoline Stations.
International journal of environmental research and public health.
2019 10; 16(21):. doi:
10.3390/ijerph16214209
. [PMID: 31671611] - Cheng Zhang, Xinglu Pan, Xiaomao Wu, Fengshou Dong, Xingang Liu, Jun Xu, Xiaohu Wu, Ming Li, Yongquan Zheng. Removal of dimethachlon from soils using immobilized cells and enzymes of a novel potential degrader Providencia stuartii JD.
Journal of hazardous materials.
2019 10; 378(?):120606. doi:
10.1016/j.jhazmat.2019.04.089
. [PMID: 31326122] - Karl Forsell, Ingrid Liljelind, Göran Ljungkvist, Rolf Nordlinder, Eva Andersson, Ralph Nilsson. Benzene Exposure and Biomarkers in Alveolar Air and Urine Among Deck Crews on Tankers Transporting Gasoline.
Annals of work exposures and health.
2019 10; 63(8):890-897. doi:
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Annals of global health.
2019 07; 85(1):. doi:
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Environmental science and pollution research international.
2018 Dec; 25(34):34046-34052. doi:
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Toxicology letters.
2018 Dec; 298(?):70-75. doi:
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Industrial health.
2018 Jul; 56(4):346-355. doi:
10.2486/indhealth.2017-0225
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International journal of environmental research and public health.
2018 04; 15(4):. doi:
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Metabolic engineering.
2018 03; 46(?):13-19. doi:
10.1016/j.ymben.2018.02.002
. [PMID: 29474840] - Christine Brückner, Mislav Oreb, Gotthard Kunze, Eckhard Boles, Joanna Tripp. An expanded enzyme toolbox for production of cis, cis-muconic acid and other shikimate pathway derivatives in Saccharomyces cerevisiae.
FEMS yeast research.
2018 03; 18(2):. doi:
10.1093/femsyr/foy017
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Journal of separation science.
2018 Jan; 41(2):501-508. doi:
10.1002/jssc.201700685
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Chemico-biological interactions.
2017 Dec; 278(?):256-268. doi:
10.1016/j.cbi.2017.09.002
. [PMID: 28899792] - Lucía G Pruneda-Alvarez, Tania Ruíz-Vera, Angeles C Ochoa-Martínez, Iván N Pérez-Maldonado. Urinary trans-trans muconic acid (exposure biomarker to benzene) and hippuric acid (exposure biomarker to toluene) concentrations in Mexican women living in high-risk scenarios of air pollution.
Archives of environmental & occupational health.
2017 Nov; 72(6):351-358. doi:
10.1080/19338244.2016.1272539
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La Clinica terapeutica.
2017 Nov; 168(6):e380-e387. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2017 Sep; 1061-1062(?):65-71. doi:
10.1016/j.jchromb.2017.07.008
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Bulletin of environmental contamination and toxicology.
2017 Aug; 99(2):258-263. doi:
10.1007/s00128-017-2130-6
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International journal of pediatric otorhinolaryngology.
2017 Feb; 93(?):157-162. doi:
10.1016/j.ijporl.2016.12.036
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PloS one.
2017; 12(9):e0183602. doi:
10.1371/journal.pone.0183602
. [PMID: 28886060] - Miguel Suástegui, Zengyi Shao. Yeast factories for the production of aromatic compounds: from building blocks to plant secondary metabolites.
Journal of industrial microbiology & biotechnology.
2016 11; 43(11):1611-1624. doi:
10.1007/s10295-016-1824-9
. [PMID: 27581441] - Piero Lovreglio, Denise Doria, Maria Enrica Fracasso, Anna Barbieri, Laura Sabatini, Ignazio Drago, Francesco S Violante, Leonardo Soleo. DNA damage and repair capacity in workers exposed to low concentrations of benzene.
Environmental and molecular mutagenesis.
2016 Mar; 57(2):151-8. doi:
10.1002/em.21990
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Environmental toxicology and pharmacology.
2016 Jan; 41(?):54-61. doi:
10.1016/j.etap.2015.11.004
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Environment international.
2015 Feb; 75(?):136-43. doi:
10.1016/j.envint.2014.10.028
. [PMID: 25461422] - Elisabetta Chellini, Maria Cristina Fondelli, Maria Teresa Maurello, Gianfranco Sciarra, Maria Cristina Aprea, Giulia Carreras. [Pollutants from a plant which burns toxic waste in the Province of Arezzo (Tuscany Region, Central Italy): human biomonitoring pilot study to evaluate the possible type of environmental exposure].
Epidemiologia e prevenzione.
2015 Jan; 39(1):28-35. doi:
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. [PMID: 25855544] - Gabriela Göethel, Natália Brucker, Angela M Moro, Mariele F Charão, Rafael Fracasso, Anelise Barth, Guilherme Bubols, Juliano Durgante, Sabrina Nascimento, Marília Baierle, Paulo H Saldiva, Solange C Garcia. Evaluation of genotoxicity in workers exposed to benzene and atmospheric pollutants.
Mutation research. Genetic toxicology and environmental mutagenesis.
2014 Aug; 770(?):61-5. doi:
10.1016/j.mrgentox.2014.05.008
. [PMID: 25344165] - Piero Lovreglio, Francesca Maffei, Mariella Carrieri, Maria N D'Errico, Ignazio Drago, Patrizia Hrelia, Giovanni B Bartolucci, Leonardo Soleo. Evaluation of chromosome aberration and micronucleus frequencies in blood lymphocytes of workers exposed to low concentrations of benzene.
Mutation research. Genetic toxicology and environmental mutagenesis.
2014 Aug; 770(?):55-60. doi:
10.1016/j.mrgentox.2014.04.022
. [PMID: 25344164] - Yoon-Hyeong Choi, Jin Hee Kim, Bo-Eun Lee, Yun-Chul Hong. Urinary benzene metabolite and insulin resistance in elderly adults.
The Science of the total environment.
2014 Jun; 482-483(?):260-8. doi:
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Toxicology and industrial health.
2014 Jun; 30(5):467-74. doi:
10.1177/0748233712458141
. [PMID: 22933555] - Neng-Zhong Xie, Hong Liang, Ri-Bo Huang, Ping Xu. Biotechnological production of muconic acid: current status and future prospects.
Biotechnology advances.
2014 May; 32(3):615-22. doi:
10.1016/j.biotechadv.2014.04.001
. [PMID: 24751381] - Hualiang Liu, Baoli Zhu, Junwen Shi. [Determination of urinary 8-hydroxy-2'-deoxyguanosine, trans, trans-muconic acid, and S-phenylmercapturic acid by liquid chromatography-mass spectrometry].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases.
2014 Feb; 32(2):142-4. doi:
NULL
. [PMID: 24630023] - Bidisha Mukherjee, Anindita Dutta, Saswati Chowdhury, Sanghita Roychoudhury, Manas Ranjan Ray. Reduction of DNA mismatch repair protein expression in airway epithelial cells of premenopausal women chronically exposed to biomass smoke.
Environmental science and pollution research international.
2014 Feb; 21(4):2826-36. doi:
10.1007/s11356-013-2218-4
. [PMID: 24146321] - Sébastien Gagné. Determination of trans,trans-muconic acid in workers' urine through ultra-performance liquid chromatography coupled to tandem mass spectrometry.
Biomedical chromatography : BMC.
2013 May; 27(5):664-8. doi:
10.1002/bmc.2844
. [PMID: 23225372] - T Tunsaringkarn, S Soogarun, A Palasuwan. Occupational exposure to benzene and changes in hematological parameters and urinary trans, trans-muconic acid.
The international journal of occupational and environmental medicine.
2013 Jan; 4(1):45-9. doi:
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. [PMID: 23279797] - Mohana Krishna Reddy Mudiam, Abhishek Chauhan, Krishna P Singh, Shailendra K Gupta, Rajeev Jain, Ratnasekhar Ch, R C Murthy. Determination of t,t-muconic acid in urine samples using a molecular imprinted polymer combined with simultaneous ethyl chloroformate derivatization and pre-concentration by dispersive liquid-liquid microextraction.
Analytical and bioanalytical chemistry.
2013 Jan; 405(1):341-9. doi:
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The Science of the total environment.
2012 Oct; 435-436(?):115-23. doi:
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La Medicina del lavoro.
2012 Sep; 103(5):338-46. doi:
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La Medicina del lavoro.
2012 Sep; 103(5):324-37. doi:
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Toxicology letters.
2012 Aug; 213(1):63-8. doi:
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Toxicology letters.
2012 Aug; 213(1):57-62. doi:
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The Analyst.
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Chemosphere.
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Indoor air.
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International archives of occupational and environmental health.
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Environmental health perspectives.
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Journal of environmental monitoring : JEM.
2011 Oct; 13(10):2921-8. doi:
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Journal of occupational and environmental medicine.
2011 Oct; 53(10):1194-8. doi:
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Environmental and molecular mutagenesis.
2011 May; 52(4):310-8. doi:
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Giornale italiano di medicina del lavoro ed ergonomia.
2011 Apr; 33(2):117-24. doi:
NULL
. [PMID: 21796919] - P Lovreglio, M Carrieri, A Barbieri, L Sabatini, M E Fracasso, D Doria, S Iavicoli, I Drago, M N D'errico, M Imbriani, F S Violante, G B Bartolucci, L Soleo. Applicability of urinary benzene to biological monitoring of occupational and environmental exposure to very low benzene concentrations.
Giornale italiano di medicina del lavoro ed ergonomia.
2011 Jan; 33(1):41-6. doi:
NULL
. [PMID: 21417138] - Tanasorn Tunsaringkarn, Jamsai Suwansaksri, Suphan Soogarun, Wattasit Siriwong, Anusorn Rungsiyothin, Kalaya Zapuang, Mark Robson. Genotoxic monitoring and benzene exposure assessment of gasoline station workers in metropolitan Bangkok: sister chromatid exchange (SCE) and urinary trans, trans-muconic acid (t,t-MA).
Asian Pacific journal of cancer prevention : APJCP.
2011; 12(1):223-7. doi:
NULL
. [PMID: 21517262] - Jin Hee Kim, Jae Yong Moon, Eun-Young Park, Kwan-Hee Lee, Yun-Chul Hong. Changes in oxidative stress biomarker and gene expression levels in workers exposed to volatile organic compounds.
Industrial health.
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Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
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