2-Methylbutyrate (BioDeep_00000898114)
代谢物信息卡片
2-Methylbutyrate
化学式: C5H9O2- (101.0602514)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 9.52%
分子结构信息
SMILES: CCC(C)C(=O)[O-]
InChI: InChI=1S/C5H10O2/c1-3-4(2)5(6)7/h4H,3H2,1-2H3,(H,6,7)/p-1
相关代谢途径
Reactome(0)
BioCyc(2)
代谢反应
6 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(1)
- epoxypseudoisoeugenol-2-methylbutanoate biosynthesis:
2-methylbutanoate + pseudoisoeugenol ⟶ epoxypseudoisoeugenol-2-methylbutanoate
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(5)
- epoxypseudoisoeugenol-2-methylbutanoate biosynthesis:
2-methylbutanoate + pseudoisoeugenol ⟶ epoxypseudoisoeugenol-2-methylbutanoate - adlupulone and adhumulone biosynthesis:
2-methylbutanoate + ATP + coenzyme A ⟶ 2-methylbutanoyl-CoA + AMP + diphosphate - superpathway of bitter acids biosynthesis:
A(H2) + O2 + deoxyhumulone ⟶ A + H2O + humulone - adlupulone and adhumulone biosynthesis:
A(H2) + O2 + deoxyadlupulone ⟶ A + H2O + adhumulone - superpathway of bitter acids biosynthesis:
ATP + coenzyme A + isobutanoate ⟶ AMP + diphosphate + isobutanoyl-CoA
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Honggang Guo, Xia Shi, Jie Han, Qianhui Ren, Zhangtai Gao, Aihuan Zhang, Haixiang Wang, Yanli Du. VOCs from fungi infected-apples attract and increase the oviposition of yellow peach moth Conogethes punctiferalis.
Pest management science.
2023 Aug; ?(?):. doi:
10.1002/ps.7727. [PMID: 37591815] - Ping-Hsun Wu, Yi-Wen Chiu, Hsin-Bai Zou, Cheng-Chih Hsu, Su-Chu Lee, Yi-Ting Lin, Yi-Chun Tsai, Mei-Chuan Kuo, Shang-Jyh Hwang. Exploring the Benefit of 2-Methylbutyric Acid in Patients Undergoing Hemodialysis Using a Cardiovascular Proteomics Approach.
Nutrients.
2019 Dec; 11(12):. doi:
10.3390/nu11123033. [PMID: 31842275] - Maoxuan Liu, Daniëlle Copmans, Jing-Guang Lu, Ming-Rong Yang, Jo Sourbron, Annelii Ny, Zhi-Hong Jiang, Peter A M de Witte, Walter Luyten. Bioassay-guided isolation of anti-seizure principles from Semen Pharbitidis using a zebrafish pentylenetetrazol seizure model.
Journal of ethnopharmacology.
2019 Mar; 232(?):130-134. doi:
10.1016/j.jep.2018.12.024. [PMID: 30572093] - C Wang, Q Liu, G Guo, W J Huo, C X Pei, S L Zhang, H Wang. Effects of concentrate-to-forage ratios and 2-methylbutyrate supplementation on ruminal fermentation, bacteria abundance and urinary excretion of purine derivatives in Chinese Simmental steers.
Journal of animal physiology and animal nutrition.
2018 Aug; 102(4):901-909. doi:
10.1111/jpn.12915. [PMID: 29717516] - C Wang, Q Liu, G Guo, W J Huo, C X Pei, S L Zhang, W Z Yang. Effects of dietary protein levels and 2-methylbutyrate on ruminal fermentation, nutrient degradability, bacterial populations and urinary purine derivatives in Simmental steers.
Journal of animal physiology and animal nutrition.
2018 Jun; 102(3):611-619. doi:
10.1111/jpn.12797. [PMID: 29095532] - Katrin Matheis, Michael Granvogl. Characterization of Key Odorants Causing a Fusty/Musty Off-Flavor in Native Cold-Pressed Rapeseed Oil by Means of the Sensomics Approach.
Journal of agricultural and food chemistry.
2016 Nov; 64(43):8168-8178. doi:
10.1021/acs.jafc.6b03527. [PMID: 27712066] - Lisiane Aurélio Knebel, Ângela Zanatta, Anelise Miotti Tonin, Mateus Grings, Leonardo de Moura Alvorcem, Moacir Wajner, Guilhian Leipnitz. 2-Methylbutyrylglycine induces lipid oxidative damage and decreases the antioxidant defenses in rat brain.
Brain research.
2012 Oct; 1478(?):74-82. doi:
10.1016/j.brainres.2012.08.039. [PMID: 22967964] - Juan Wang, Yufeng Ma, Wen Li, Fangdi Hu, Tongqiang Chen, Xiaoli Shen, Shilan Feng. Study on pharmacokinetics and tissue distribution of pteryxin in mice by ultra-pressure liquid chromatography with tandem mass spectrometry.
Biomedical chromatography : BMC.
2012 Jul; 26(7):802-7. doi:
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Journal of food science.
2008 Aug; 73(6):C500-5. doi:
10.1111/j.1750-3841.2008.00851.x. [PMID: 19241541] - C Wyss. Fatty acids synthesized by oral treponemes in chemically defined media.
FEMS microbiology letters.
2007 Apr; 269(1):70-6. doi:
10.1111/j.1574-6968.2006.00609.x. [PMID: 17229060] - Gregory Kaler, David M Truong, Derina E Sweeney, Darren W Logan, Megha Nagle, Wei Wu, Satish A Eraly, Sanjay K Nigam. Olfactory mucosa-expressed organic anion transporter, Oat6, manifests high affinity interactions with odorant organic anions.
Biochemical and biophysical research communications.
2006 Dec; 351(4):872-6. doi:
10.1016/j.bbrc.2006.10.136. [PMID: 17094945] - Yukiko Tokitomo, Martin Steinhaus, Andrea Büttner, Peter Schieberle. Odor-active constituents in fresh pineapple (Ananas comosus [L.] Merr.) by quantitative and sensory evaluation.
Bioscience, biotechnology, and biochemistry.
2005 Jul; 69(7):1323-30. doi:
10.1271/bbb.69.1323. [PMID: 16041138] - Stanley H Korman, Brage S Andresen, Avraham Zeharia, Alisa Gutman, Avihu Boneh, James J Pitt. 2-ethylhydracrylic aciduria in short/branched-chain acyl-CoA dehydrogenase deficiency: application to diagnosis and implications for the R-pathway of isoleucine oxidation.
Clinical chemistry.
2005 Mar; 51(3):610-7. doi:
10.1373/clinchem.2004.043265. [PMID: 15615815] - Márta Dregus, Hans-Georg Schmarr, Eisuke Takahisa, Karl-Heinz Engel. Enantioselective analysis of methyl-branched alcohols and acids in rhubarb (Rheum rhabarbarum L.) stalks.
Journal of agricultural and food chemistry.
2003 Nov; 51(24):7086-91. doi:
10.1021/jf030466b. [PMID: 14611176] - Ana G Pérez, Raquel Olías, Pilar Luaces, Carlos Sanz. Biosynthesis of strawberry aroma compounds through amino acid metabolism.
Journal of agricultural and food chemistry.
2002 Jul; 50(14):4037-42. doi:
10.1021/jf011465r. [PMID: 12083879] - B A Annous, L A Becker, D O Bayles, D P Labeda, B J Wilkinson. Critical role of anteiso-C15:0 fatty acid in the growth of Listeria monocytogenes at low temperatures.
Applied and environmental microbiology.
1997 Oct; 63(10):3887-94. doi:
10.1128/aem.63.10.3887-3894.1997. [PMID: 9327552] - T Tsujita, A Nakagawa, K Shirai, Y Saito, H Okuda. Methyl butyrate-hydrolyzing activity of hepatic triglyceride lipase from rat post-heparin plasma.
The Journal of biological chemistry.
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NULL. [PMID: 6469999] - M J COON, N S B ABRAHAMSEN, G S GREENE. The relation of alpha-methyl-butyrate to isoleucine metabolism. II. Propionate formation.
The Journal of biological chemistry.
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