Flavin mononucleotide(3-) (BioDeep_00000897860)

   


代谢物信息卡片


Flavin mononucleotide(3-)

化学式: C17H18N4O9P-3 (453.0811)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 100%

分子结构信息

SMILES: CC1=CC2=C(C=C1C)N(C3=NC(=NC(=O)C3=N2)[O-])CC(C(C(COP(=O)([O-])[O-])O)O)O
InChI: InChI=1S/C17H21N4O9P/c1-7-3-9-10(4-8(7)2)21(15-13(18-9)16(25)20-17(26)19-15)5-11(22)14(24)12(23)6-30-31(27,28)29/h3-4,11-12,14,22-24H,5-6H2,1-2H3,(H,20,25,26)(H2,27,28,29)/p-3/t11-,12+,14-/m0/s1

描述信息

D018977 - Micronutrients > D014815 - Vitamins
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同义名列表

1 个代谢物同义名

Flavin mononucleotide(3-)



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(31)

BioCyc(45)

PlantCyc(10)

代谢反应

263 个相关的代谢反应过程信息。

Reactome(228)

BioCyc(34)

WikiPathways(1)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Xiaoying Jing, Shanchao Hong, Jian Zhang, Xue Yang, Xianlong Geng, Yan Ye, Zhigang Hu. A rapid and quantitative detection method for plasma soluble growth stimulating gene protein 2 based on time resolved fluorescence immunochromatography. Analytical methods : advancing methods and applications. 2022 06; 14(22):2179-2187. doi: 10.1039/d2ay00120a. [PMID: 35608240]
  • Changjing Zhang, Leilei Zhu, Shuaifei Lu, Mengyuan Li, Ming Bai, Yucheng Li, Erping Xu. The antidepressant-like effect of formononetin on chronic corticosterone-treated mice. Brain research. 2022 05; 1783(?):147844. doi: 10.1016/j.brainres.2022.147844. [PMID: 35218705]
  • E V Ekusheva, V B Voitenkov, O A Rizakhanova. [The effectiveness of cytoflavin in complex therapy of patients with the coronavirus infection COVID-19]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2021; 121(12):33-39. doi: 10.17116/jnevro202112112133. [PMID: 35041310]
  • M V Putilina, N V Teplova, K I Bairova, A E Petrikeeva, N I Shabalina. [The result of prospective randomized study CITADEL - the efficacy and safety of drug cytoflavin in postcovid rehabilitation]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2021; 121(10):45-51. doi: 10.17116/jnevro202112110145. [PMID: 34874654]
  • Sweta Narayanan Iyer, Nemeshwaree Behary, Vincent Nierstrasz, Jinping Guan. Glow-in-the-Dark Patterned PET Nonwoven Using Air-Atmospheric Plasma Treatment and Vitamin B2-Derivative (FMN). Sensors (Basel, Switzerland). 2020 Nov; 20(23):. doi: 10.3390/s20236816. [PMID: 33260671]
  • M Cicuéndez, V S Silva, J Santos, A Coimbra, H Oliveira, M Ayán-Varela, J I Paredes, S Villar-Rodil, M Vila. MoS2 flakes stabilized with DNA/RNA nucleotides: In vitro cell response. Materials science & engineering. C, Materials for biological applications. 2019 Jul; 100(?):11-22. doi: 10.1016/j.msec.2019.02.002. [PMID: 30948045]
  • Yujie Liu, Wei Wu, Zhongzhou Chen. Structures of glycolate oxidase from Nicotiana benthamiana reveal a conserved pH sensor affecting the binding of FMN. Biochemical and biophysical research communications. 2018 09; 503(4):3050-3056. doi: 10.1016/j.bbrc.2018.08.092. [PMID: 30143257]
  • Benjamin Ricken, Boris A Kolvenbach, Christian Bergesch, Dirk Benndorf, Kevin Kroll, Hynek Strnad, Čestmír Vlček, Ricardo Adaixo, Frederik Hammes, Patrick Shahgaldian, Andreas Schäffer, Hans-Peter E Kohler, Philippe F-X Corvini. FMNH2-dependent monooxygenases initiate catabolism of sulfonamides in Microbacterium sp. strain BR1 subsisting on sulfonamide antibiotics. Scientific reports. 2017 Nov; 7(1):15783. doi: 10.1038/s41598-017-16132-8. [PMID: 29150672]
  • Congyun Jin, Yoshiaki Yao, Atsushi Yonezawa, Satoshi Imai, Hiroki Yoshimatsu, Yuki Otani, Tomohiro Omura, Shunsaku Nakagawa, Takayuki Nakagawa, Kazuo Matsubara. Riboflavin Transporters RFVT/SLC52A Mediate Translocation of Riboflavin, Rather than FMN or FAD, across Plasma Membrane. Biological & pharmaceutical bulletin. 2017; 40(11):1990-1995. doi: 10.1248/bpb.b17-00292. [PMID: 29093349]
  • A V Deriugina, A V Shumilova. [An influence of cytoflavin on oxidative stress and activity of Na/K-ATPase of erythrocytes after brain trauma]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2017 ; 117(11):51-55. doi: 10.17116/jnevro201711711151-55. [PMID: 29265087]
  • Jiansong Ren, Gwen Murphy, Jinhu Fan, Sanford M Dawsey, Philip R Taylor, Jacob Selhub, Youlin Qiao, Christian C Abnet. Prospective study of serum B vitamins levels and oesophageal and gastric cancers in China. Scientific reports. 2016 10; 6(?):35281. doi: 10.1038/srep35281. [PMID: 27748414]
  • V A Dorovskikh, O N Li, N V Simonova, M A Shtarberg. [EFFECT OF CITOFLAVIN ON THE PARAMETERS OF LIPID PEROXIDATION IN BLOOD PLASMA OF RATS UNDER COLD STRESS CONDITIONS.]. Eksperimental'naia i klinicheskaia farmakologiia. 2016; 79(7):29-34. doi: . [PMID: 29782743]
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  • I V Zadnipryanyi, O S Tretyakova, T P Sataeva. [Investigation of the antioxidant activity and cardioprotective effect of reamberin and cytoflavin in newborn rats exposed to chronic hemic hypoxia]. Arkhiv patologii. 2015 Nov; 77(6):39-44. doi: 10.17116/patol201577639-44. [PMID: 26841648]
  • I V Gatskikh, O F Veselova, I N Brikman, T P Shalda, E L Varygina, M N Kuznetsov, A V Shul'min, M M Petrova. [EFFECTIVENESS OF CYTOFLAVIN FOR THE CORRECTION OF COGNITIVE IMPAIRMENTS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS]. Eksperimental'naia i klinicheskaia farmakologiia. 2015; 78(11):21-5. doi: . [PMID: 27017701]
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  • N I Zhernakova, T V Gorbach, O V Romashchenko, V V Rumbesht. Age-related features of Cytoflavin effectiveness during experimental myocardial ischemia. Bulletin of experimental biology and medicine. 2014 Apr; 156(6):785-8. doi: 10.1007/s10517-014-2450-z. [PMID: 24824697]
  • N V Tsygan, A P Trashkov. [Brain functional state and cytoprotective potential in model of acute cerebral hypoxia (experimental research)]. Patologicheskaia fiziologiia i eksperimental'naia terapiia. 2013 Oct; ?(4):10-6. doi: NULL. [PMID: 24640767]
  • Abhigyan Sengupta, Wilbee D Sasikala, Arnab Mukherjee, Partha Hazra. Comparative study of flavins binding with human serum albumin: a fluorometric, thermodynamic, and molecular dynamics approach. Chemphyschem : a European journal of chemical physics and physical chemistry. 2012 Jun; 13(8):2142-53. doi: 10.1002/cphc.201200044. [PMID: 22532419]
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  • Shu-Chun Chuang, Rachael Stolzenberg-Solomon, Per Magne Ueland, Stein Emil Vollset, Øivind Midttun, Anja Olsen, Anne Tjønneland, Kim Overvad, Marie-Christine Boutron-Ruault, Sophie Morois, Françoise Clavel-Chapelon, Birgit Teucher, Rudolf Kaaks, Cornelia Weikert, Heiner Boeing, Antonia Trichopoulou, Vassiliki Benetou, Androniki Naska, Mazda Jenab, Nadia Slimani, Isabelle Romieu, Dominique S Michaud, Domenico Palli, Sabina Sieri, Salvatore Panico, Carlotta Sacerdote, Rosario Tumino, Guri Skeie, Eric J Duell, Laudina Rodriguez, Esther Molina-Montes, José Marı A Huerta, Nerea Larrañaga, Aurelio Barricarte Gurrea, Dorthe Johansen, Jonas Manjer, Weimin Ye, Malin Sund, Petra H M Peeters, Suzanne Jeurnink, Nicholas Wareham, Kay-Tee Khaw, Francesca Crowe, Elio Riboli, Bas Bueno-de-Mesquita, Paolo Vineis. A U-shaped relationship between plasma folate and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition. European journal of cancer (Oxford, England : 1990). 2011 Aug; 47(12):1808-16. doi: 10.1016/j.ejca.2011.02.007. [PMID: 21411310]
  • Rajender Kumar, Vinita Hooda, C S Pundir. Purification and partial characterization of oxalate oxidase from leaves of forage Sorghum (Sorghum vulgare var. KH-105) seedlings. Indian journal of biochemistry & biophysics. 2011 Feb; 48(1):42-6. doi: . [PMID: 21469601]
  • S O Rogatkin, N N Volodin, M G Degtiareva, O V Grebennikova, M Sh Marganiia, N D Serova. [Current approaches to cerebroprotective treatment of premature newborns in reanimation and intensive care departments]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2011; 111(1):27-32. doi: NULL. [PMID: 21350408]
  • I V Gordiushina, R P Savchenko, D S Sukhanov, A Iu Petrov, M G Romantsov. [Antioxidant and membranoprotector treatment of chronic pyelonephritis]. Eksperimental'naia i klinicheskaia farmakologiia. 2011; 74(4):27-30. doi: NULL. [PMID: 21678656]
  • E V Silina, S A Rumiantseva, S B Bolevich, N I Men'shova. [Course of free radical processes and prognosis of ischemic and hemorrhagic stroke]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2011; 111(12 Pt 2):36-42. doi: NULL. [PMID: 22792747]
  • Aikaterini T Vasilaki, Donald C McMillan, John Kinsella, Andrew Duncan, Denis St J O'Reilly, Dinesh Talwar. Relation between riboflavin, flavin mononucleotide and flavin adenine dinucleotide concentrations in plasma and red cells in patients with critical illness. Clinica chimica acta; international journal of clinical chemistry. 2010 Nov; 411(21-22):1750-5. doi: 10.1016/j.cca.2010.07.024. [PMID: 20667447]
  • S N Karpishchenko, S N Zheregelia, S I Glushkov. [Using cytoflavin for correcting x-ray contrasting agent-induced nephropathy]. Eksperimental'naia i klinicheskaia farmakologiia. 2010 Oct; 73(10):40-2. doi: NULL. [PMID: 21254514]
  • V A Kashuro, S I Glushkov, L V Minaeva, T M Novikova. [Experimental study on cytoflavin pharmacological correction of cyclophosphamide-induced toxic affections of the liver and kidneys]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 2010; 55(9-10):29-32. doi: NULL. [PMID: 21400751]
  • Benjamin Yazdanpanah, Katja Wiegmann, Vladimir Tchikov, Oleg Krut, Carola Pongratz, Michael Schramm, Andre Kleinridders, Thomas Wunderlich, Hamid Kashkar, Olaf Utermöhlen, Jens C Brüning, Stefan Schütze, Martin Krönke. Riboflavin kinase couples TNF receptor 1 to NADPH oxidase. Nature. 2009 Aug; 460(7259):1159-63. doi: 10.1038/nature08206. [PMID: 19641494]
  • Carmen G Gherasim, Uzma Zaman, Ashraf Raza, Ruma Banerjee. Impeded electron transfer from a pathogenic FMN domain mutant of methionine synthase reductase and its responsiveness to flavin supplementation. Biochemistry. 2008 Nov; 47(47):12515-22. doi: 10.1021/bi8008328. [PMID: 18980384]
  • G A Livanov, A N Lodiagin, I P Nikolaeva, B V Batotsyrenov. [The diagnosis and treatment of pulmonary hyperhydration in critically ill patients with acute poisoning by neurotropic agents]. Anesteziologiia i reanimatologiia. 2008 Nov; ?(6):27-30. doi: NULL. [PMID: 19227289]
  • Slavica Mijatovic, Giovanni Gadda. Oxidation of alkyl nitronates catalyzed by 2-nitropropane dioxygenase from Hansenula mrakii. Archives of biochemistry and biophysics. 2008 May; 473(1):61-8. doi: 10.1016/j.abb.2008.02.029. [PMID: 18329375]
  • Masayuki Akimoto, Yuko Sato, Toshimi Okubo, Hiroaki Todo, Tetsuya Hasegawa, Kenji Sugibayashi. Conversion of FAD to FMN and riboflavin in plasma: effects of measuring method. Biological & pharmaceutical bulletin. 2006 Aug; 29(8):1779-82. doi: 10.1248/bpb.29.1779. [PMID: 16880644]
  • Jean-Yves Hautem, Claire Morel, Rémy Couderc, Fathi Moussa. Liquid chromatographic determination of B(2) vitamers in human plasma and whole blood. Clinical chemistry. 2006 May; 52(5):907-8. doi: 10.1373/clinchem.2005.065920. [PMID: 16638966]
  • Horatiu Olteanu, Kirsten R Wolthers, Andrew W Munro, Nigel S Scrutton, Ruma Banerjee. Kinetic and thermodynamic characterization of the common polymorphic variants of human methionine synthase reductase. Biochemistry. 2004 Feb; 43(7):1988-97. doi: 10.1021/bi035910i. [PMID: 14967039]
  • Astrid Lorenz, Ralf Kaldenhoff, Rainer Hertel. A major integral protein of the plant plasma membrane binds flavin. Protoplasma. 2003 May; 221(1-2):19-30. doi: 10.1007/s00709-002-0066-z. [PMID: 12768338]
  • Friederike Traunmüller, Michael Ramharter, Heimo Lagler, Florian Thalhammer, Peter G Kremsner, Wolfgang Graninger, Stefan Winkler. Normal riboflavin status in malaria patients in Gabon. The American journal of tropical medicine and hygiene. 2003 Feb; 68(2):182-5. doi: . [PMID: 12641409]
  • José Mauro Granjeiro, Carmen Verissima Ferreira, Paulo Afonso Granjeiro, Cinthia Celestino Da Silva, Eulázio Mikio Taga, Pedro Luiz Onofre Volpe, Hiroshi Aoyama. Inhibition of bovine kidney low molecular mass phosphotyrosine protein phosphatase by uric acid. Journal of enzyme inhibition and medicinal chemistry. 2002 Oct; 17(5):345-50. doi: 10.1080/1475636021000013939. [PMID: 12683751]
  • Steinar Hustad, Michelle C McKinley, Helene McNulty, Jørn Schneede, J J Strain, John M Scott, Per Magne Ueland. Riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in human plasma and erythrocytes at baseline and after low-dose riboflavin supplementation. Clinical chemistry. 2002 Sep; 48(9):1571-7. doi: . [PMID: 12194936]
  • O Sawada, T Ishida, K Horiike. Frontal gel chromatographic analysis of the interaction of a protein with self-associating ligands: aberrant saturation in the binding of flavins to bovine serum albumin. Journal of biochemistry. 2001 Jun; 129(6):899-907. doi: 10.1093/oxfordjournals.jbchem.a002935. [PMID: 11388904]
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