Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu (BioDeep_00000897444)
代谢物信息卡片
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu
化学式: C62H89N17O14 (1295.6774574)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=CN=CN4)C(=O)NC(CC(C)C)C(=O)[O-])NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)C(C(C)C)NC(=O)C(CCC[NH+]=C(N)N)NC(=O)C(CC(=O)[O-])[NH3+]
InChI: InChI=1S/C62H89N17O14/c1-7-35(6)51(78-56(87)44(25-37-17-19-40(80)20-18-37)74-58(89)50(34(4)5)77-53(84)42(15-11-21-68-62(64)65)71-52(83)41(63)28-49(81)82)59(90)75-46(27-39-30-67-32-70-39)60(91)79-22-12-16-48(79)57(88)73-43(24-36-13-9-8-10-14-36)54(85)72-45(26-38-29-66-31-69-38)55(86)76-47(61(92)93)23-33(2)3/h8-10,13-14,17-20,29-35,41-48,50-51,80H,7,11-12,15-16,21-28,63H2,1-6H3,(H,66,69)(H,67,70)(H,71,83)(H,72,85)(H,73,88)(H,74,89)(H,75,90)(H,76,86)(H,77,84)(H,78,87)(H,81,82)(H,92,93)(H4,64,65,68)/t35-,41-,42-,43-,44-,45-,46-,47-,48-,50-,51-/m0/s1
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Longyue Zhou, Shankang Chen, Yuanyi Wei, Yihui Sun, Yifan Yang, Bingqi Lin, Yuhao Li, Chunxia Wang. Glycyrrhizic acid restores the downregulated hepatic ACE2 signaling in the attenuation of mouse steatohepatitis.
European journal of pharmacology.
2024 Feb; ?(?):176365. doi:
10.1016/j.ejphar.2024.176365. [PMID: 38316247] - Na Li, Qiongyu Zhang, Shiyu Dai, Wenzhuo Rao, Haitao Shi, Li Ding, Meiling Hong. Angiotensin-(1-7) plays an important role in regulating spermatogenesis in Trachemys scripta elegans under salinity stress.
The Journal of experimental biology.
2024 Jan; 227(2):. doi:
10.1242/jeb.246742. [PMID: 38149682] - Dan Ye, Jiamin Liu, Long Lin, Pengwei Hou, Tianshun Feng, Shousen Wang. The Ang-(1-7)/MasR axis ameliorates neuroinflammation in hypothermic traumatic brain injury in mice by modulating phenotypic transformation of microglia.
PloS one.
2024; 19(5):e0303150. doi:
10.1371/journal.pone.0303150. [PMID: 38728304] - Jose A Godoy-Lugo, Dora A Mendez, Ruben Rodriguez, Akira Nishiyama, Daisuke Nakano, Jose G Soñanez-Organis, Rudy M Ortiz. Improved lipogenesis gene expression in liver is associated with elevated plasma angiotensin 1-7 after AT1 receptor blockade in insulin-resistant OLETF rats.
Molecular and cellular endocrinology.
2022 09; 555(?):111729. doi:
10.1016/j.mce.2022.111729. [PMID: 35921918] - Xin-Yue Liu, Jing-Chao Su, Xin-Fang Zhang, Shui-Ying Xiang, Chun-Mei Yi, Yu-Wen Wang, Cai-Yun Wang, Zi-Bing Liu. [Electroacupuncture preconditioning improves pulmonary function via inhibiting inflammatory response and up-regulating expression of ACE2 and Ang (1-7) in lipopolysaccharide-induced acute lung injury rats].
Zhen ci yan jiu = Acupuncture research.
2022 Aug; 47(8):684-9. doi:
10.13702/j.1000-0607.20210979. [PMID: 36036101] - Santoshi Sahu, C R Patil, Sachin Kumar, Subbu Apparsundaram, Ramesh K Goyal. Role of ACE2-Ang (1-7)-Mas axis in post-COVID-19 complications and its dietary modulation.
Molecular and cellular biochemistry.
2022 Jan; 477(1):225-240. doi:
10.1007/s11010-021-04275-2. [PMID: 34655418] - Hala Attia, Norah Albekairi, Layal Albdeirat, Arwa Soliman, Reem Rajab, Hend Alotaibi, Rehab Ali, Amira Badr. Chrysin Attenuates Fructose-Induced Nonalcoholic Fatty Liver in Rats via Antioxidant and Anti-Inflammatory Effects: The Role of Angiotensin-Converting Enzyme 2/Angiotensin (1-7)/Mas Receptor Axis.
Oxidative medicine and cellular longevity.
2022; 2022(?):9479456. doi:
10.1155/2022/9479456. [PMID: 35720181] - Li Zhu, Zhen Liu, Li-Ping Huang, Hou-Rong Zhou, Yu Cao, Xue-Ping Yang, Bing-Jin Wang, Zi-Li Yang, Jing Chen. Angiotensin (1-7) Alleviates Postresuscitation Myocardial Dysfunction by Suppressing Oxidative Stress Through the Phosphoinositide 3-Kinase, Protein Kinase B, and Endothelial Nitric Oxide Synthase Signaling Pathway.
Journal of cardiovascular pharmacology.
2021 07; 78(1):e65-e76. doi:
10.1097/fjc.0000000000001037. [PMID: 33929390] - Chengliang Wang, Liying Ren, Shankang Chen, Huihui Zheng, Yifan Yang, Tieguang Gu, Yuhao Li, Chunxia Wang. Longdan Xiegan Tang attenuates liver injury and hepatic insulin resistance by regulating the angiotensin-converting enzyme 2/Ang (1-7)/Mas axis-mediated anti-inflammatory pathway in rats.
Journal of ethnopharmacology.
2021 Jun; 274(?):114072. doi:
10.1016/j.jep.2021.114072. [PMID: 33781876] - Nan-Nan Sha, Jia-Li Zhang, Christina Chui-Wa Poon, Wen-Xiong Li, Yue Li, Yi-Fei Wang, Wei Shi, Fu-Hui Lin, Wen-Ping Lin, Yong-Jun Wang, Yan Zhang. Differential responses of bone to angiotensin II and angiotensin(1-7): beneficial effects of ANG(1-7) on bone with exposure to high glucose.
American journal of physiology. Endocrinology and metabolism.
2021 01; 320(1):E55-E70. doi:
10.1152/ajpendo.00158.2020. [PMID: 33103451] - Li-Ni Song, Jing-Yi Liu, Ting-Ting Shi, Yi-Chen Zhang, Zhong Xin, Xi Cao, Jin-Kui Yang. Angiotensin-(1-7), the product of ACE2 ameliorates NAFLD by acting through its receptor Mas to regulate hepatic mitochondrial function and glycolipid metabolism.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2020 12; 34(12):16291-16306. doi:
10.1096/fj.202001639r. [PMID: 33078906] - Xihao Du, Xuejiao Zeng, Jia Zhang, Kun Pan, Liying Song, Ji Zhou, Li Zhou, Yuquan Xie, Qinghua Sun, Wenzhen Ge, Renjie Chen, Jinzhuo Zhao, Haidong Kan. Ambient fine particulate matter induced the elevation of blood pressure through ACE2/Ang(1-7) pathway: The evidence from urine metabolites.
Ecotoxicology and environmental safety.
2020 Oct; 203(?):111044. doi:
10.1016/j.ecoenv.2020.111044. [PMID: 32888613] - Hongguan Zhang, Yude Liu, Lian Rao, Yanyou Cen, Kaili Cheng. Upregulation of the angiotensin-converting enzyme 2-angiotensin-(1-7)-Mas receptor axis by a combination of Yinyanghuo (Herba Epimedii Brevicornus) and Cheqianzi (Semen Plantaginis) improves erectile function in spontaneously hypertensive rats.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan.
2020 10; 40(5):836-844. doi:
10.19852/j.cnki.jtcm.2020.05.014. [PMID: 33000585] - Thaiany G Souza-Silva, Diego F Vilas-Boas, Elda Gonçalves-Santos, Ana Lia Mazzeti, Ivo S Caldas, Reggiani V Gonçalves, Lívia F Diniz, Rômulo D Novaes. Impact of diminazene aceturate on renin-angiotensin system, infectious myocarditis and skeletal myositis in mice: An in vitro and in vivo study.
Life sciences.
2020 Sep; 257(?):118067. doi:
10.1016/j.lfs.2020.118067. [PMID: 32652140] - Omeed Rahimi, Jay Kirby, Jasmina Varagic, Brian Westwood, E Ann Tallant, Patricia E Gallagher. Angiotensin-(1-7) reduces doxorubicin-induced cardiac dysfunction in male and female Sprague-Dawley rats through antioxidant mechanisms.
American journal of physiology. Heart and circulatory physiology.
2020 04; 318(4):H883-H894. doi:
10.1152/ajpheart.00224.2019. [PMID: 32083974] - Zhancui Dang, Shanshan Su, Guoen Jin, Xingmei Nan, Lan Ma, Zhanqiang Li, Dianxiang Lu, Rili Ge. Tsantan Sumtang attenuated chronic hypoxia-induced right ventricular structure remodeling and fibrosis by equilibrating local ACE-AngII-AT1R/ACE2-Ang1-7-Mas axis in rat.
Journal of ethnopharmacology.
2020 Mar; 250(?):112470. doi:
10.1016/j.jep.2019.112470. [PMID: 31862407] - Bonan Zhang, Hong Xu, Yi Zhang, Xue Yi, Guizhen Zhang, Xin Zhang, Dingjie Xu, Xuemin Gao, Shifeng Li, Ying Zhu, Hui Zhang, Zhongqiu Wei, Shumin Li, Lijuan Zhang, Ruimin Wang, Fang Yang. Targeting the RAS axis alleviates silicotic fibrosis and Ang II-induced myofibroblast differentiation via inhibition of the hedgehog signaling pathway.
Toxicology letters.
2019 Oct; 313(?):30-41. doi:
10.1016/j.toxlet.2019.05.023. [PMID: 31181250] - Xuemin Gao, Hong Xu, Bonan Zhang, Tao Tao, Yalou Liu, Dingjie Xu, Wenchen Cai, Zhongqiu Wei, Shifeng Li, Hui Zhang, Na Mao, Guizhen Zhang, Dan Li, Fuyu Jin, Shumin Li, Lijuan Zhang, Heliang Liu, Xiaohui Hao, Fang Yang. Interaction of N-acetyl-seryl-aspartyl-lysyl-proline with the angiotensin-converting enzyme 2-angiotensin-(1-7)-Mas axis attenuates pulmonary fibrosis in silicotic rats.
Experimental physiology.
2019 10; 104(10):1562-1574. doi:
10.1113/ep087515. [PMID: 31290182] - Juexiao Gong, Yihui Shen, Peng Li, Kun Zhao, Xuguan Chen, Yong Li, Yanhui Sheng, Bin Zhou, Xiangqing Kong. Superoxide anions mediate the effects of angiotensin (1-7) analog, alamandine, on blood pressure and sympathetic activity in the paraventricular nucleus.
Peptides.
2019 08; 118(?):170101. doi:
10.1016/j.peptides.2019.170101. [PMID: 31199949] - Qiuhua Chen, Junjun Liu, Wanqiu Wang, Suzi Liu, Xiaoting Yang, Mingqi Chen, Lu Cheng, Jun Lu, Tao Guo, Fengjie Huang. Sini decoction ameliorates sepsis-induced acute lung injury via regulating ACE2-Ang (1-7)-Mas axis and inhibiting the MAPK signaling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2019 Jul; 115(?):108971. doi:
10.1016/j.biopha.2019.108971. [PMID: 31102910] - Deborah de Farias Lelis, Daniela Fernanda de Freitas, Amanda Souto Machado, Thaísa Soares Crespo, Sérgio Henrique Sousa Santos. Angiotensin-(1-7), Adipokines and Inflammation.
Metabolism: clinical and experimental.
2019 06; 95(?):36-45. doi:
10.1016/j.metabol.2019.03.006. [PMID: 30905634] - Qiong-Feng Chen, Hua Hao, Xiao-Dong Kuang, Quan-Dong Hu, Yong-Hong Huang, Xiao-Yan Zhou. BML-111, a lipoxin receptor agonist, protects against acute injury via regulating the renin angiotensin-aldosterone system.
Prostaglandins & other lipid mediators.
2019 02; 140(?):9-17. doi:
10.1016/j.prostaglandins.2018.11.001. [PMID: 30412790] - Vivian Paulino Figueiredo, Maria Andrea Barbosa, Uberdan Guilherme Mendes de Castro, Aline Cruz Zacarias, Frank Silva Bezerra, Renata Guerra de Sá, Wanderson Geraldo de Lima, Robson Augusto Souza Dos Santos, Andréia Carvalho Alzamora. Antioxidant Effects of Oral Ang-(1-7) Restore Insulin Pathway and RAS Components Ameliorating Cardiometabolic Disturbances in Rats.
Oxidative medicine and cellular longevity.
2019; 2019(?):5868935. doi:
10.1155/2019/5868935. [PMID: 31396301] - In-Ae Jang, Eun Nim Kim, Ji Hee Lim, Min Young Kim, Tae Hyun Ban, Hye Eun Yoon, Cheol Whee Park, Yoon Sik Chang, Bum Soon Choi. Effects of Resveratrol on the Renin-Angiotensin System in the Aging Kidney.
Nutrients.
2018 Nov; 10(11):. doi:
10.3390/nu10111741. [PMID: 30424556] - Wenfei Ding, Xue Li, Weihua Wu, Hongyan He, Ying Li, Lichao Gao, Linwang Gan, Mengping Wang, Santao Ou, Jian Liu. [Aliskiren inhibits angiotensin II/angiotensin 1-7(Ang II/Ang1-7) signal pathway in rats with diabetic nephropathy].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology.
2018 Oct; 34(10):891-895. doi:
. [PMID: 30554582] - Junjun Liu, Qiuhua Chen, Suzi Liu, Xiaoting Yang, Yan Zhang, Fengjie Huang. Sini decoction alleviates E. coli induced acute lung injury in mice via equilibrating ACE-AngII-AT1R and ACE2-Ang-(1-7)-Mas axis.
Life sciences.
2018 Sep; 208(?):139-148. doi:
10.1016/j.lfs.2018.07.013. [PMID: 29990483] - Xuebo Pan, Yihui Shao, Fan Wu, Yuan Wang, Rongrong Xiong, Jujia Zheng, Haishan Tian, Baile Wang, Yanfang Wang, Yi Zhang, Zongsheng Han, Aijuan Qu, Haixia Xu, Aihua Lu, Tianxin Yang, Xiaokun Li, Aimin Xu, Jie Du, Zhuofeng Lin. FGF21 Prevents Angiotensin II-Induced Hypertension and Vascular Dysfunction by Activation of ACE2/Angiotensin-(1-7) Axis in Mice.
Cell metabolism.
2018 Jun; 27(6):1323-1337.e5. doi:
10.1016/j.cmet.2018.04.002. [PMID: 29706566] - Brenda de Oliveira da Silva, Luciane Carla Alberici, Letícia Ferreira Ramos, Caio Mateus Silva, Marina Bonfogo da Silveira, Carlos R P Dechant, Scott L Friedman, Kumiko Koibuchi Sakane, Letícia Rocha Gonçalves, Karen C M Moraes. Altered global microRNA expression in hepatic stellate cells LX-2 by angiotensin-(1-7) and miRNA-1914-5p identification as regulator of pro-fibrogenic elements and lipid metabolism.
The international journal of biochemistry & cell biology.
2018 05; 98(?):137-155. doi:
10.1016/j.biocel.2018.02.018. [PMID: 29524604] - Mostafa A Rabie, Mai A Abd El Fattah, Noha N Nassar, Hanan S El-Abhar, Dalaal M Abdallah. Angiotensin 1-7 ameliorates 6-hydroxydopamine lesions in hemiparkinsonian rats through activation of MAS receptor/PI3K/Akt/BDNF pathway and inhibition of angiotensin II type-1 receptor/NF-κB axis.
Biochemical pharmacology.
2018 05; 151(?):126-134. doi:
10.1016/j.bcp.2018.01.047. [PMID: 29428223] - Hidechika Morimoto, Jun Mori, Hisakazu Nakajima, Yasuhiro Kawabe, Yusuke Tsuma, Shota Fukuhara, Kazuki Kodo, Kazuya Ikoma, Satoaki Matoba, Gavin Y Oudit, Hajime Hosoi. Angiotensin 1-7 stimulates brown adipose tissue and reduces diet-induced obesity.
American journal of physiology. Endocrinology and metabolism.
2018 02; 314(2):E131-E138. doi:
10.1152/ajpendo.00192.2017. [PMID: 29066463] - Joao Marcus Oliveira Andrade, Deborah de Farias Lelis, Valeria Mafra, Junio Cota. The Angiotensin Converting Enzyme 2 (ACE2), Gut Microbiota, and Cardiovascular Health.
Protein and peptide letters.
2017 Nov; 24(9):827-832. doi:
10.2174/0929866524666170728145333. [PMID: 28758592] - Eliete Dalla Corte Frantz, Renata Frauches Medeiros, Isabele Gomes Giori, Juliana Bittencourt Silveira Lima, Thais Bento-Bernardes, Thaiane Gadioli Gaique, Caroline Fernandes-Santos, Tiago Fernandes, Edilamar Menezes Oliveira, Carla Paulo Vieira, Carlos Adam Conte-Junior, Karen Jesus Oliveira, Antonio Claudio Lucas Nobrega. Exercise training modulates the hepatic renin-angiotensin system in fructose-fed rats.
Experimental physiology.
2017 09; 102(9):1208-1220. doi:
10.1113/ep085924. [PMID: 28626963] - Quandong Hu, Zhenzhen Hu, Qiongfeng Chen, Yonghong Huang, Zi Mao, Fangyun Xu, Xiaoyan Zhou. BML-111 equilibrated ACE-AngII-AT1R and ACE2-Ang-(1-7)-Mas axis to protect hepatic fibrosis in rats.
Prostaglandins & other lipid mediators.
2017 07; 131(?):75-82. doi:
10.1016/j.prostaglandins.2017.08.008. [PMID: 28822808] - Mohammad Yaseen Khan, Vimal Kumar. Mechanism of antihypertensive effect of Mucuna pruriens L. seed extract and its isolated compounds.
Journal of complementary & integrative medicine.
2017 Jun; 14(4):. doi:
10.1515/jcim-2017-0014. [PMID: 28640753] - Carolina Campos Lima Moreira, Fabíola Cesário Lourenço, Érica Guilhen Mario, Robson Augusto Souza Santos, Leida Maria Botion, Valéria Ernestânia Chaves. Long-term effects of angiotensin-(1-7) on lipid metabolism in the adipose tissue and liver.
Peptides.
2017 06; 92(?):16-22. doi:
10.1016/j.peptides.2017.04.004. [PMID: 28438644] - Ying Mu, Zhaohui Xu, Xuanxuan Zhou, Huinan Zhang, Qian Yang, Yunlong Zhang, Yanhua Xie, Juan Kang, Feng Li, Siwang Wang. 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside Attenuates Ischemia/Reperfusion-Induced Brain Injury in Rats by Promoting Angiogenesis.
Planta medica.
2017 May; 83(8):676-683. doi:
10.1055/s-0042-120544. [PMID: 27894149] - Bae Huey Tee, See Ziau Hoe, Swee Hung Cheah, Sau Kuen Lam. Effects of Root Extracts of Eurycoma longifolia Jack on Corpus Cavernosum of Rat.
Medical principles and practice : international journal of the Kuwait University, Health Science Centre.
2017; 26(3):258-265. doi:
10.1159/000464363. [PMID: 28226311] - Luz Ibarra-Lara, Leonardo Del Valle-Mondragón, Elizabeth Soria-Castro, Juan C Torres-Narváez, Francisca Pérez-Severiano, María Sánchez-Aguilar, Margarita Ramírez-Ortega, Luz G Cervantes-Pérez, Gustavo S Pastelín-Hernández, Víctor H Oidor-Chan, Gabriela Zarco-Olvera, Alicia Sánchez-Mendoza. Peroxisome proliferator-activated receptor-α stimulation by clofibrate favors an antioxidant and vasodilator environment in a stressed left ventricle.
Pharmacological reports : PR.
2016 Aug; 68(4):692-702. doi:
10.1016/j.pharep.2016.03.002. [PMID: 27110876] - Luan Kelves M Souza, Lucas A D Nicolau, Nayara A Sousa, Thiago S L Araújo, Francisca Beatriz M Sousa, Douglas S Costa, Fabiana M Souza, Dvison M Pacífico, Conceição S Martins, Renan O Silva, Marcellus H L P Souza, Gilberto S Cerqueira, Jand Venes R Medeiros. Diminazene aceturate, an angiotensin-converting enzyme II activator, prevents gastric mucosal damage in mice: Role of the angiotensin-(1-7)/Mas receptor axis.
Biochemical pharmacology.
2016 07; 112(?):50-9. doi:
10.1016/j.bcp.2016.05.010. [PMID: 27241079] - Diego A Luna-Vital, Katie Liang, Elvira González de Mejía, Guadalupe Loarca-Piña. Dietary peptides from the non-digestible fraction of Phaseolus vulgaris L. decrease angiotensin II-dependent proliferation in HCT116 human colorectal cancer cells through the blockade of the renin-angiotensin system.
Food & function.
2016 May; 7(5):2409-19. doi:
10.1039/c6fo00093b. [PMID: 27156533] - Anna M Papinska, Maira Soto, Christopher J Meeks, Kathleen E Rodgers. Long-term administration of angiotensin (1-7) prevents heart and lung dysfunction in a mouse model of type 2 diabetes (db/db) by reducing oxidative stress, inflammation and pathological remodeling.
Pharmacological research.
2016 05; 107(?):372-380. doi:
10.1016/j.phrs.2016.02.026. [PMID: 26956523] - Xi Cao, Fangyuan Yang, Tingting Shi, Mingxia Yuan, Zhong Xin, Rongrong Xie, Sen Li, Hongbing Li, Jin-Kui Yang. Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis activates Akt signaling to ameliorate hepatic steatosis.
Scientific reports.
2016 Feb; 6(?):21592. doi:
10.1038/srep21592. [PMID: 26883384] - Teshome Aboye, Christopher J Meeks, Subhabrata Majumder, Alexander Shekhtman, Kathleen Rodgers, Julio A Camarero. Design of a MCoTI-Based Cyclotide with Angiotensin (1-7)-Like Activity.
Molecules (Basel, Switzerland).
2016 Jan; 21(2):152. doi:
10.3390/molecules21020152. [PMID: 26821010] - M K A, N M Aziz, M A E, R A Rifaai. Possible contribution of nitric oxide and prostaglandin in the protective effect of angiotensin (1-7) against stress induced gastric ulceration in adult male albino rats.
Bratislavske lekarske listy.
2016; 117(12):715-721. doi:
10.4149/bll_2016_137. [PMID: 28127968] - Bae Huey Tee, See Ziau Hoe, Swee Hung Cheah, Sau Kuen Lam. First Report of Eurycoma longifolia Jack Root Extract Causing Relaxation of Aortic Rings in Rats.
BioMed research international.
2016; 2016(?):1361508. doi:
10.1155/2016/1361508. [PMID: 27800486] - Qiong-ying Wang, Wei Liang, Cheng Jiang, Ning-yin Li, Han Xu, Mi-na Yang, Xin Lin, Heng Yu, Peng Chang, Jing Yu. [Effect of Astragali Radix in improving early renal damage in metabolic syndrome rats through ACE2/Mas pathway].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2015 Nov; 40(21):4245-50. doi:
. [PMID: 27071265] - Kai Y Mak, Ruth Chin, Sharon C Cunningham, Miriam R Habib, Joseph Torresi, Alexandra F Sharland, Ian E Alexander, Peter W Angus, Chandana B Herath. ACE2 Therapy Using Adeno-associated Viral Vector Inhibits Liver Fibrosis in Mice.
Molecular therapy : the journal of the American Society of Gene Therapy.
2015 Sep; 23(9):1434-43. doi:
10.1038/mt.2015.92. [PMID: 25997428] - Hai-Yan Jin, Lai-Jiang Chen, Zhen-Zhou Zhang, Ying-Le Xu, Bei Song, Ran Xu, Gavin Y Oudit, Ping-Jin Gao, Ding-Liang Zhu, Jiu-Chang Zhong. Deletion of angiotensin-converting enzyme 2 exacerbates renal inflammation and injury in apolipoprotein E-deficient mice through modulation of the nephrin and TNF-alpha-TNFRSF1A signaling.
Journal of translational medicine.
2015 Aug; 13(?):255. doi:
10.1186/s12967-015-0616-8. [PMID: 26245758] - Rodrigo A Fraga-Silva, Fabiana P Costa-Fraga, Fabrizio Montecucco, Mikael Sturny, Younoss Faye, François Mach, Graziano Pelli, Vinayak Shenoy, Rafaela F da Silva, Mohan K Raizada, Robson A S Santos, Nikolaos Stergiopulos. Diminazene protects corpus cavernosum against hypercholesterolemia-induced injury.
The journal of sexual medicine.
2015 Feb; 12(2):289-302. doi:
10.1111/jsm.12757. [PMID: 25411084] - Yaning Zheng, Lin Tang, Wenhan Huang, Ruyu Yan, Feifeng Ren, Lei Luo, Ling Zhang. Anti-Inflammatory Effects of Ang-(1-7) in Ameliorating HFD-Induced Renal Injury through LDLr-SREBP2-SCAP Pathway.
PloS one.
2015; 10(8):e0136187. doi:
10.1371/journal.pone.0136187. [PMID: 26291618] - Vinayak Shenoy, Kwang-Chul Kwon, Anandharajan Rathinasabapathy, Shina Lin, Guiying Jin, Chunjuan Song, Pollob Shil, Anand Nair, Yanfei Qi, Qiuhong Li, Joseph Francis, Michael J Katovich, Henry Daniell, Mohan K Raizada. Oral delivery of Angiotensin-converting enzyme 2 and Angiotensin-(1-7) bioencapsulated in plant cells attenuates pulmonary hypertension.
Hypertension (Dallas, Tex. : 1979).
2014 Dec; 64(6):1248-59. doi:
10.1161/hypertensionaha.114.03871. [PMID: 25225206] - Pollob K Shil, Kwang-Chul Kwon, Ping Zhu, Amrisha Verma, Henry Daniell, Qiuhong Li. Oral delivery of ACE2/Ang-(1-7) bioencapsulated in plant cells protects against experimental uveitis and autoimmune uveoretinitis.
Molecular therapy : the journal of the American Society of Gene Therapy.
2014 Dec; 22(12):2069-2082. doi:
10.1038/mt.2014.179. [PMID: 25228068] - Yan Gao, Jian Ping Gao, Chang Xun Chen, Hui Lin Wang, Juan Guo, Rong Wu. Beneficial effects of houttuynin on ventricular remodeling induced by coronary artery ligation in rats.
European journal of pharmacology.
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