(2E,6E,10E)-3,7,11,15-Tetramethylhexadeca-2,6,10,14-tetraen-1-yl diphosphate (BioDeep_00000897432)

   


代谢物信息卡片


(2E,6E,10E)-3,7,11,15-Tetramethylhexadeca-2,6,10,14-tetraen-1-yl diphosphate

化学式: C20H33O7P2-3 (447.1701428)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 95.65%

分子结构信息

SMILES: CC(=CCCC(=CCCC(=CCCC(=CCOP(=O)([O-])OP(=O)([O-])[O-])C)C)C)C
InChI: InChI=1S/C20H36O7P2/c1-17(2)9-6-10-18(3)11-7-12-19(4)13-8-14-20(5)15-16-26-29(24,25)27-28(21,22)23/h9,11,13,15H,6-8,10,12,14,16H2,1-5H3,(H,24,25)(H2,21,22,23)/p-3/b18-11+,19-13+,20-15+

描述信息

COVID info from COVID-19 Disease Map
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

1 个代谢物同义名

(2E,6E,10E)-3,7,11,15-Tetramethylhexadeca-2,6,10,14-tetraen-1-yl diphosphate



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(4)

BioCyc(28)

PlantCyc(14)

代谢反应

335 个相关的代谢反应过程信息。

Reactome(48)

BioCyc(26)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(261)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Xuan Song, Yao-Guo Qin, Yi-Han Zhang, Yu-Bei Zhou, Zheng-Xi Li. Farnesyl/geranylgeranyl diphosphate synthases regulate the biosynthesis of alarm pheromone in a unique manner in the vetch aphid Megoura viciae. Insect molecular biology. 2022 Dec; ?(?):. doi: 10.1111/imb.12826. [PMID: 36533988]
  • Xin Shu, Jiaqi Wu, Tao Zhang, Xiaoyu Ma, Zuoqin Du, Jin Xu, Jingcan You, Liqun Wang, Ni Chen, Mao Luo, Jianbo Wu. Statin-Induced Geranylgeranyl Pyrophosphate Depletion Promotes PCSK9-Dependent Adipose Insulin Resistance. Nutrients. 2022 Dec; 14(24):. doi: 10.3390/nu14245314. [PMID: 36558473]
  • Xin Shu, Jiaqi Wu, Tao Zhang, Xiaoyu Ma, Zuoqin Du, Jin Xu, Jingcan You, Liqun Wang, Ni Chen, Mao Luo, Jianbo Wu. Statin-Induced Geranylgeranyl Pyrophosphate Depletion Promotes Ferroptosis-Related Senescence in Adipose Tissue. Nutrients. 2022 Oct; 14(20):. doi: 10.3390/nu14204365. [PMID: 36297049]
  • Feifei Xu, Zining Wang, Hongxia Zhang, Jiemin Chen, Xiaojuan Wang, Lei Cui, Chunyuan Xie, Mengyun Li, Fang Wang, Penghui Zhou, Jinyun Liu, Peng Huang, Xiaodong Xia, Xiaojun Xia. Mevalonate Blockade in Cancer Cells Triggers CLEC9A+ Dendritic Cell-Mediated Antitumor Immunity. Cancer research. 2021 09; 81(17):4514-4528. doi: 10.1158/0008-5472.can-20-3977. [PMID: 34266895]
  • Sarah Ötzkan, Walter E Muller, W Gibson Wood, Gunter P Eckert. Effects of 7,8-Dihydroxyflavone on Lipid Isoprenoid and Rho Protein Levels in Brains of Aged C57BL/6 Mice. Neuromolecular medicine. 2021 03; 23(1):130-139. doi: 10.1007/s12017-020-08640-0. [PMID: 33377988]
  • Marie Chantal Lemfack, Wolfgang Brandt, Katja Krüger, Alexandra Gurowietz, Jacky Djifack, Jan-Philip Jung, Marius Hopf, Heiko Noack, Björn Junker, Stephan von Reuß, Birgit Piechulla. Reaction mechanism of the farnesyl pyrophosphate C-methyltransferase towards the biosynthesis of pre-sodorifen pyrophosphate by Serratia plymuthica 4Rx13. Scientific reports. 2021 02; 11(1):3182. doi: 10.1038/s41598-021-82521-9. [PMID: 33542330]
  • Chi Zhang, Dan-Dan Jin, Xi-Ying Wang, Lian Lou, Jian Yang. Key Enzymes for the Mevalonate Pathway in the Cardiovascular System. Journal of cardiovascular pharmacology. 2021 02; 77(2):142-152. doi: 10.1097/fjc.0000000000000952. [PMID: 33538531]
  • Lisha Wei, Yan-Yan Zheng, Jie Sun, Pei Wang, Tao Tao, Yeqiong Li, Xin Chen, Yongjuan Sang, Danyang Chong, Wei Zhao, Yuwei Zhou, Ye Wang, Zhihui Jiang, Tiantian Qiu, Chao-Jun Li, Min-Sheng Zhu, Xuena Zhang. GGPP depletion initiates metaflammation through disequilibrating CYB5R3-dependent eicosanoid metabolism. The Journal of biological chemistry. 2020 11; 295(47):15988-16001. doi: 10.1074/jbc.ra120.015020. [PMID: 32913122]
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  • Ramasamy P Kumar, Benjamin R Morehouse, Jason O Matos, Karan Malik, Hongkun Lin, Isaac J Krauss, Daniel D Oprian. Structural Characterization of Early Michaelis Complexes in the Reaction Catalyzed by (+)-Limonene Synthase from Citrus sinensis Using Fluorinated Substrate Analogues. Biochemistry. 2017 03; 56(12):1716-1725. doi: 10.1021/acs.biochem.7b00144. [PMID: 28272876]
  • Sibongile Mafu, Prema Sambandaswami Karunanithi, Teresa Ann Palazzo, Bronwyn Lee Harrod, Selina Marakana Rodriguez, Iris Natalie Mollhoff, Terrence Edward O'Brien, Shen Tong, Oliver Fiehn, Dean J Tantillo, Jörg Bohlmann, Philipp Zerbe. Biosynthesis of the microtubule-destabilizing diterpene pseudolaric acid B from golden larch involves an unusual diterpene synthase. Proceedings of the National Academy of Sciences of the United States of America. 2017 01; 114(5):974-979. doi: 10.1073/pnas.1612901114. [PMID: 28096378]
  • Yu-Sheng Yeh, Tsuyoshi Goto, Nobuyuki Takahashi, Kahori Egawa, Haruya Takahashi, Huei-Fen Jheng, Young-Il Kim, Teruo Kawada. Geranylgeranyl pyrophosphate performs as an endogenous regulator of adipocyte function via suppressing the LXR pathway. Biochemical and biophysical research communications. 2016 09; 478(3):1317-22. doi: 10.1016/j.bbrc.2016.08.119. [PMID: 27569282]
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  • Meng Zhang, Ping Su, Yong-Jin Zhou, Xiu-Juan Wang, Yu-Jun Zhao, Yu-Jia Liu, Yu-Ru Tong, Tian-Yuan Hu, Lu-Qi Huang, Wei Gao. Identification of geranylgeranyl diphosphate synthase genes from Tripterygium wilfordii. Plant cell reports. 2015 Dec; 34(12):2179-88. doi: 10.1007/s00299-015-1860-3. [PMID: 26449416]
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