trans-Caffeate (BioDeep_00000897404)

   


代谢物信息卡片


trans-Caffeate

化学式: C9H7O4- (179.0344322)
中文名称:
谱图信息: 最多检出来源 Viridiplantae(plant) 55.56%

分子结构信息

SMILES: C1=CC(=C(C=C1C=CC(=O)O)O)[O-]
InChI: InChI=1S/C9H8O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1-5,10-11H,(H,12,13)/p-1/b4-2+

描述信息

The conjugate base of trans-caffeic acid; major species at pH 7.3.

同义名列表

1 个代谢物同义名

trans-Caffeate



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(4)

PlantCyc(5)

代谢反应

7 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(6)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Ehsan Ahmadifar, Sedigheh Mohammadzadeh, Naser Kalhor, Farzin Salehi, Mahboubeh Eslami, Amine Zaretabar, Mohsen S Moghadam, Seyed H Hoseinifar, Hien Van Doan. Effects of caffeic acid on the growth performance, growth genes, digestive enzyme activity, and serum immune parameters of beluga (Huso huso). Journal of experimental zoology. Part A, Ecological and integrative physiology. 2022 08; 337(7):715-723. doi: 10.1002/jez.2607. [PMID: 35652427]
  • Veronica F Salau, Ochuko L Erukainure, Omamuyovwi M Ijomone, Md Shahidul Islam. Caffeic acid regulates glucose homeostasis and inhibits purinergic and cholinergic activities while abating oxidative stress and dyslipidaemia in fructose-streptozotocin-induced diabetic rats. The Journal of pharmacy and pharmacology. 2022 Jul; 74(7):973-984. doi: 10.1093/jpp/rgac021. [PMID: 35640634]
  • Jingyang Hong, Taihua Mu, Hongnan Sun, Christophe Blecker, Aurore Richel. Photoprotective effects of sweet potato leaf polyphenols and caffeic acid against UV-induced skin-damage in BALB/C nude mice. Food & function. 2022 Jul; 13(13):7075-7087. doi: 10.1039/d2fo00425a. [PMID: 35695741]
  • Raghda Abdelnasser Singab, Nooran Sherif Elleboudy, Walid Faisal Elkhatib, Mahmoud Abdulmegead Yassein, Nadia Adelhaleem Hassouna. Improvement of caffeic acid biotransformation into para-hydroxybenzoic acid by Candida albicans CI-24 via gamma irradiation and model-based optimization. Biotechnology and applied biochemistry. 2022 Apr; 69(2):469-478. doi: 10.1002/bab.2124. [PMID: 33576532]
  • Maria Kuznowicz, Tomasz Rębiś, Artur Jędrzak, Grzegorz Nowaczyk, Mirosław Szybowicz, Teofil Jesionowski. Glucose determination using amperometric non-enzymatic sensor based on electroactive poly(caffeic acid)@MWCNT decorated with CuO nanoparticles. Mikrochimica acta. 2022 03; 189(4):159. doi: 10.1007/s00604-022-05256-y. [PMID: 35348884]
  • Sabeeha Ali, Manzar Alam, Fatima Khatoon, Urooj Fatima, Abdelbaset Mohamed Elasbali, Mohd Adnan, Asimul Islam, Md Imtaiyaz Hassan, Mejdi Snoussi, Vincenzo De Feo. Natural products can be used in therapeutic management of COVID-19: Probable mechanistic insights. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022 Mar; 147(?):112658. doi: 10.1016/j.biopha.2022.112658. [PMID: 35066300]
  • Solomon E Owumi, Chioma E Irozuru, Uche O Arunsi, Adegboyega K Oyelere. Caffeic acid protects against DNA damage, oxidative and inflammatory mediated toxicities, and upregulated caspases activation in the hepatorenal system of rats treated with aflatoxin B1. Toxicon : official journal of the International Society on Toxinology. 2022 Feb; 207(?):1-12. doi: 10.1016/j.toxicon.2021.12.021. [PMID: 34995555]
  • David S Goldstein, Patti Sullivan, Abraham Corrales, Risa Isonaka, Janna Gelsomino, Jamie Cherup, Genessis Castillo, Courtney Holmes. Multiple catechols in human plasma after drinking caffeinated or decaffeinated coffee. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2021 Nov; 1185(?):122988. doi: 10.1016/j.jchromb.2021.122988. [PMID: 34731744]
  • Isadora Caruso Fontana Oliveira, Edson Hideaki Yoshida, Murilo Melo Juste Dini, Ana Beatriz Olívio Paschoal, José Carlos Cogo, Maria Alice da Cruz-Höfling, Stephen Hyslop, Yoko Oshima-Franco. Evaluation of Protection by Caffeic Acid, Chlorogenic Acid, Quercetin and Tannic Acid against the In Vitro Neurotoxicity and In Vivo Lethality of Crotalus durissus terrificus (South American Rattlesnake) Venom. Toxins. 2021 11; 13(11):. doi: 10.3390/toxins13110801. [PMID: 34822584]
  • Maryam Dehdashti Moghadam, Hasan Baghshani, Hamideh Ghodrati Azadi, Zahra Moosavi. Ameliorative Effects of Caffeic Acid Against Arsenic-Induced Testicular Injury in Mice. Biological trace element research. 2021 Oct; 199(10):3772-3780. doi: 10.1007/s12011-020-02518-9. [PMID: 33394308]
  • Tahany Saad Abdelwahab, Rania Ellisy Abdelhamed, Eman Noaman Ali, Nahla Ahmed Mansour, Mohga Shafik Abdalla. Evaluation of Silver Nanoparticles Caffeic Acid Complex Compound as New Potential Therapeutic Agent against Cancer Incidence in Mice. Asian Pacific journal of cancer prevention : APJCP. 2021 Oct; 22(10):3189-3201. doi: 10.31557/apjcp.2021.22.10.3189. [PMID: 34710995]
  • Cheng-Wei Huang, Shih-Yi Lee, Tzu-Tang Wei, Yueh-Hsiung Kuo, Shao-Tung Wu, Hui-Chun Ku. A novel caffeic acid derivative prevents renal remodeling after ischemia/reperfusion injury. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2021 Oct; 142(?):112028. doi: 10.1016/j.biopha.2021.112028. [PMID: 34399201]
  • Nellysha Namela Muhammad Abdul Kadar, Fairus Ahmad, Seong Lin Teoh, Mohamad Fairuz Yahaya. Caffeic Acid on Metabolic Syndrome: A Review. Molecules (Basel, Switzerland). 2021 Sep; 26(18):. doi: 10.3390/molecules26185490. [PMID: 34576959]
  • Halil Ibrahim Guler, Gizem Tatar, Oktay Yildiz, Ali Osman Belduz, Sevgi Kolayli. Investigation of potential inhibitor properties of ethanolic propolis extracts against ACE-II receptors for COVID-19 treatment by molecular docking study. Archives of microbiology. 2021 Aug; 203(6):3557-3564. doi: 10.1007/s00203-021-02351-1. [PMID: 33950349]
  • Isabel Cristina da Costa Araldi, Thiele Piber de Souza, Marina de Souza Vencato, Thainara de Andrade Fortes, Camila Benaduce Emanuelli Mello, Juliana Sorraila de Oliveira, Guilherme Lopes Dornelles, Cinthia Melazzo de Andrade, Roberto Marinho Maciel, Cristiane Cademartori Danesi, Amanda Leitão Gindri, Alencar Kolinski Machado, Liliane de Freitas Bauermann. Preclinical safety assessment of the crude extract from Sida rhombifolia L. aerial parts in experimental models of acute and repeated-dose 28 days toxicity in rats. Regulatory toxicology and pharmacology : RTP. 2021 Aug; 124(?):104974. doi: 10.1016/j.yrtph.2021.104974. [PMID: 34139276]
  • Milagros Fanny Vera Castro, Naiara Stefanello, Charles Elias Assmann, Jucimara Baldissarelli, Margarete Dulce Bagatini, Aniélen Dutra da Silva, Pauline da Costa, Loren Borba, Ivana Beatrice Mânica da Cruz, Vera Maria Morsch, Maria Rosa Chitolina Schetinger. Modulatory effects of caffeic acid on purinergic and cholinergic systems and oxi-inflammatory parameters of streptozotocin-induced diabetic rats. Life sciences. 2021 Jul; 277(?):119421. doi: 10.1016/j.lfs.2021.119421. [PMID: 33785337]
  • Jingyu Ren, Yanzhong Zhen, Jian Wang, Jie Li. Catalytic degradation of caffeic acid by DBD plasma and Mn doped cobalt oxyhydroxide catalyst. Chemosphere. 2021 Jul; 275(?):130101. doi: 10.1016/j.chemosphere.2021.130101. [PMID: 33984910]
  • Caigui Xiang, Moting Liu, Qiukai Lu, Chen Fan, Huimin Lu, Chunlan Feng, Xiaoqian Yang, Heng Li, Wei Tang. Blockade of TLRs-triggered macrophage activation by caffeic acid exerted protective effects on experimental ulcerative colitis. Cellular immunology. 2021 07; 365(?):104364. doi: 10.1016/j.cellimm.2021.104364. [PMID: 33932876]
  • Lin Sun, Ananya Srinivas, Ron C Runnebaum. Understanding the Impact of Key Wine Components on the Use of a Non-Swelling Ion-Exchange Resin for Wine Protein Fining Treatment. Molecules (Basel, Switzerland). 2021 Jun; 26(13):. doi: 10.3390/molecules26133905. [PMID: 34206735]
  • Maizatul Hasyima Omar, Rocío González Barrio, Gema Pereira-Caro, Tahani Mazyad Almutairi, Alan Crozier. In vitro catabolism of 3',4'-dihydroxycinnamic acid by human colonic microbiota. International journal of food sciences and nutrition. 2021 Jun; 72(4):511-517. doi: 10.1080/09637486.2020.1850650. [PMID: 33238790]
  • Nada Oršolić, Damir Sirovina, Dyana Odeh, Goran Gajski, Vedran Balta, Lidija Šver, Maja Jazvinšćak Jembrek. Efficacy of Caffeic Acid on Diabetes and Its Complications in the Mouse. Molecules (Basel, Switzerland). 2021 May; 26(11):. doi: 10.3390/molecules26113262. [PMID: 34071554]
  • Şevki Adem, Volkan Eyupoglu, Iqra Sarfraz, Azhar Rasul, Ameer Fawad Zahoor, Muhammad Ali, Mohnad Abdalla, Ibrahim M Ibrahim, Abdo A Elfiky. Caffeic acid derivatives (CAFDs) as inhibitors of SARS-CoV-2: CAFDs-based functional foods as a potential alternative approach to combat COVID-19. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2021 May; 85(?):153310. doi: 10.1016/j.phymed.2020.153310. [PMID: 32948420]
  • SiYu Li, WenHan Pei, Tailin Guo, Hui Zhang. Distributions of eight bioactive components in rat tissues administered Marsdenia tenacissima extract orally detected through UPLC-MS/MS. Biomedical chromatography : BMC. 2021 Apr; 35(4):e5034. doi: 10.1002/bmc.5034. [PMID: 33226666]
  • Salvio Suárez-García, Tullio V F Esposito, Jenna Neufeld-Peters, Marta Bergamo, Hua Yang, Katayoun Saatchi, Paul Schaffer, Urs O Häfeli, Daniel Ruiz-Molina, Cristina Rodríguez-Rodríguez, Fernando Novio. Hybrid Metal-Phenol Nanoparticles with Polydopamine-like Coating for PET/SPECT/CT Imaging. ACS applied materials & interfaces. 2021 Mar; 13(9):10705-10718. doi: 10.1021/acsami.0c20612. [PMID: 33635046]
  • Gyeong Yun Jeon, Mi-Hyun Nam, Kwang-Won Lee. Inhibitory effect of caffeic acid on advanced glycation end product-induced renal fibrosis in vitro: A potential therapeutic target. Journal of food science. 2021 Feb; 86(2):579-586. doi: 10.1111/1750-3841.15588. [PMID: 33448051]
  • Xiangyang Wang, Yuexin Qian, Xue Li, Xue Jia, Zhexuan Yan, Min Han, Miao Qiao, Xiaohui Ma, Yang Chu, Shuiping Zhou, Wenzhi Yang. Rapid determination of rosmarinic acid and its two bioactive metabolites in the plasma of rats by LC-MS/MS and application to a pharmacokinetics study. Biomedical chromatography : BMC. 2021 Feb; 35(2):e4984. doi: 10.1002/bmc.4984. [PMID: 33025603]
  • Shubhada Mangrulkar, Pranav Shah, Sonali Navnage, Priyanka Mazumdar, Dinesh Chaple. Phytophospholipid Complex of Caffeic Acid: Development, In vitro Characterization, and In Vivo Investigation of Antihyperlipidemic and Hepatoprotective Action in Rats. AAPS PharmSciTech. 2021 Jan; 22(1):28. doi: 10.1208/s12249-020-01887-7. [PMID: 33404939]
  • Tao Wang, Hin Kiu Lee, Grace Gar Lee Yue, Arthur Chi Kong Chung, Clara Bik San Lau, Zongwei Cai. A novel binary matrix consisting of graphene oxide and caffeic acid for the analysis of scutellarin and its metabolites in mouse kidney by MALDI imaging. The Analyst. 2021 Jan; 146(1):289-295. doi: 10.1039/d0an01539c. [PMID: 33140762]
  • Deep Bhowmik, Rajat Nandi, Rahul Jagadeesan, Niranjan Kumar, Amresh Prakash, Diwakar Kumar. Identification of potential inhibitors against SARS-CoV-2 by targeting proteins responsible for envelope formation and virion assembly using docking based virtual screening, and pharmacokinetics approaches. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 2020 10; 84(?):104451. doi: 10.1016/j.meegid.2020.104451. [PMID: 32640381]
  • Ali Soleimanzadeh, Naseh Talavi, Vahid Shafiepour Yourdshahi, Mustafa Numan Bucak. Caffeic acid improves microscopic sperm parameters and antioxidant status of buffalo (Bubalus bubalis) bull semen following freeze-thawing process. Cryobiology. 2020 08; 95(?):29-35. doi: 10.1016/j.cryobiol.2020.06.010. [PMID: 32590017]
  • Ishfaq Ahmed, Hong Lin, Lili Xu, Shuang Li, Joana Costa, Isabel Mafra, Guanzhi Chen, Xiang Gao, Zhenxing Li. Immunomodulatory Effect of Laccase/Caffeic Acid and Transglutaminase in Alleviating Shrimp Tropomyosin (Met e 1) Allergenicity. Journal of agricultural and food chemistry. 2020 Jul; 68(29):7765-7778. doi: 10.1021/acs.jafc.0c02366. [PMID: 32609503]
  • Mei Xue, Yong Bian, Yalin Liu, Junjie Zhou, Jianjun Xu, Liang Zhang, Xi Huang. Danggui Buxue decoction ameliorates lipid metabolic defects involved in the initiation of diabetic atherosclerosis; identification of active compounds. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. 2020 06; 40(3):414-421. doi: 10.19852/j.cnki.jtcm.2020.03.009. [PMID: 32506855]
  • Izabela Grabska-Kobylecka, Justyna Kaczmarek-Bak, Malgorzata Figlus, Anna Prymont-Przyminska, Anna Zwolinska, Agata Sarniak, Anna Wlodarczyk, Andrzej Glabinski, Dariusz Nowak. The Presence of Caffeic Acid in Cerebrospinal Fluid: Evidence That Dietary Polyphenols Can Cross the Blood-Brain Barrier in Humans. Nutrients. 2020 May; 12(5):. doi: 10.3390/nu12051531. [PMID: 32466115]
  • Waseem Feeroze Bhat, Azaj Ahmed, Shabeena Abbass, Mohammad Afsar, Bilqees Bano, Akbar Masood. Deciphering the Nature of Caffeic Acid to Inhibit the HSA Aggregation Induced by Glyoxal. Protein and peptide letters. 2020; 27(8):725-735. doi: 10.2174/0929866527666200129105141. [PMID: 32003651]
  • Hui Xia, Qin He, Hong Wang, Yongming Wang, Yang Yang, Yuke Li, Jiahua Zhang, Zhihao Chen, Junqing Yang. Treatment with either COX-2 inhibitor or 5-LOX inhibitor causes no compensation between COX-2 pathway and 5-LOX pathway in chronic aluminum overload-induced liver injury in rats. Fundamental & clinical pharmacology. 2019 Oct; 33(5):535-543. doi: 10.1111/fcp.12465. [PMID: 30903708]
  • T O Ajiboye, R A Ajala-Lawal, A B Adeyiga. Caffeic acid abrogates 1,3-dichloro-2-propanol-induced hepatotoxicity by upregulating nuclear erythroid-related factor 2 and downregulating nuclear factor-kappa B. Human & experimental toxicology. 2019 Sep; 38(9):1092-1101. doi: 10.1177/0960327119851257. [PMID: 31142131]
  • Canan Sevimli-Gur, Ozlem Yesil-Celiktas. Cytotoxicity screening of supercritical fluid extracted seaweeds and phenylpropanoids. Molecular biology reports. 2019 Aug; 46(4):3691-3699. doi: 10.1007/s11033-019-04812-9. [PMID: 31004301]
  • Mahtab Amiri, Jafar Navabi, Yalda Shokoohinia, Fatemeh Heydarpour, Gholamreza Bahrami, Leila Behbood, Padide Derakhshandeh, Saeideh Momtaz, Mohammad Hosein Farzaei. Efficacy and safety of a standardized extract from Achillea wilhelmsii C. Koch in patients with ulcerative colitis: A randomized double blind placebo-controlled clinical trial. Complementary therapies in medicine. 2019 Aug; 45(?):262-268. doi: 10.1016/j.ctim.2019.05.001. [PMID: 31331572]
  • Kiran George, Nisha Susan Thomas, Raman Malathi. Modulatory Effect of Selected Dietary Phytochemicals on Delayed Rectifier K+ Current in Human Prostate Cancer Cells. The Journal of membrane biology. 2019 06; 252(2-3):195-206. doi: 10.1007/s00232-019-00070-9. [PMID: 31165179]
  • Wanqing Zhang, Lukuan Zong, Shanqin Liu, Shuai Pei, Yongsheng Zhang, Xiaoman Ding, Bo Jiang, Yuping Zhang. An electrochemical sensor based on electro-polymerization of caffeic acid and Zn/Ni-ZIF-8-800 on glassy carbon electrode for the sensitive detection of acetaminophen. Biosensors & bioelectronics. 2019 Apr; 131(?):200-206. doi: 10.1016/j.bios.2019.01.069. [PMID: 30844596]
  • Bruna Taciane da Silva Bortoleti, Fernanda Tomiotto-Pellissier, Manoela Daiele Gonçalves, Milena Menegazzo Miranda-Sapla, João Paulo Assolini, Amanda Cristina Carloto, Débora Messagi Lima, Guilherme Ferreira Silveira, Ricardo Sergio Almeida, Idessania Nazareth Costa, Ivete Conchon-Costa, Wander Rogério Pavanelli. Caffeic acid has antipromastigote activity by apoptosis-like process; and anti-amastigote by TNF-α/ROS/NO production and decreased of iron availability. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2019 Apr; 57(?):262-270. doi: 10.1016/j.phymed.2018.12.035. [PMID: 30802712]
  • Sevdan Yilmaz. Effects of dietary caffeic acid supplement on antioxidant, immunological and liver gene expression responses, and resistance of Nile tilapia, Oreochromis niloticus to Aeromonas veronii. Fish & shellfish immunology. 2019 Mar; 86(?):384-392. doi: 10.1016/j.fsi.2018.11.068. [PMID: 30502464]
  • Tássia B Pessato, Natália C de Carvalho, Daniella de Figueiredo, Talita C Colomeu, Luís Gustavo R Fernandes, Flavia M Netto, Ricardo de L Zollner. Complexation of whey protein with caffeic acid or (-)-epigallocatechin-3-gallate as a strategy to induce oral tolerance to whey allergenic proteins. International immunopharmacology. 2019 Mar; 68(?):115-123. doi: 10.1016/j.intimp.2018.12.047. [PMID: 30620923]
  • Xuemei Mu, Xike Xu, Xin Guo, Peiming Yang, Jiang Du, Nan Mi, Taofang Cheng, Lu Lu, Xiaopo Qi, Xinyu Wang, Jing Ning, Weidong Zhang, Ji Ye. Identification and characterization of chemical constituents in Dengzhan Shengmai Capsule and their metabolites in rat plasma by ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2019 Feb; 1108(?):54-64. doi: 10.1016/j.jchromb.2019.01.010. [PMID: 30682539]
  • Ya-Li Wang, Qian Zhang, Shi-Jun Yin, Liang Cai, Yu-Xiu Yang, Wen-Jing Liu, Yuan-Jia Hu, Hua Chen, Feng-Qing Yang. Screening of blood-activating active components from Danshen-Honghua herbal pair by spectrum-effect relationship analysis. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2019 Feb; 54(?):149-158. doi: 10.1016/j.phymed.2018.09.176. [PMID: 30668364]
  • Manas Kinra, Devinder Arora, Jayesh Mudgal, K S R Pai, Chamallamudi Mallikarjuna Rao, Madhavan Nampoothiri. Effect of Caffeic Acid on Ischemia-Reperfusion-Induced Acute Renal Failure in Rats. Pharmacology. 2019; 103(5-6):315-319. doi: 10.1159/000497474. [PMID: 30870859]
  • Zhao Namula, Maki Hirata, Manita Wittayarat, Fuminori Tanihara, Nhien Thi Nguyen, Takayuki Hirano, Masahiro Nii, Takeshige Otoi. Effects of chlorogenic acid and caffeic acid on the quality of frozen-thawed boar sperm. Reproduction in domestic animals = Zuchthygiene. 2018 Dec; 53(6):1600-1604. doi: 10.1111/rda.13288. [PMID: 30053311]
  • Xiaoman Xu, Guanhong Xu, Fangdi Wei, Yao Cen, Menglan Shi, Xia Cheng, Yuying Chai, Muhammad Sohail, Qin Hu. Carbon dots coated with molecularly imprinted polymers: A facile bioprobe for fluorescent determination of caffeic acid. Journal of colloid and interface science. 2018 Nov; 529(?):568-574. doi: 10.1016/j.jcis.2018.06.050. [PMID: 29960234]
  • Pedram Shokouh, Per Bendix Jeppesen, Kjeld Hermansen, Christoffer Laustsen, Hans Stødkilde-Jørgensen, Stephen Jacques Hamilton-Dutoit, Mette Søndergaard Schmedes, Haiyun Qi, Thomas Stokholm Nørlinger, Søren Gregersen. Effects of Unfiltered Coffee and Bioactive Coffee Compounds on the Development of Metabolic Syndrome Components in a High-Fat-/High-Fructose-Fed Rat Model. Nutrients. 2018 Oct; 10(10):. doi: 10.3390/nu10101547. [PMID: 30347674]
  • Yuting Fan, Yuexiang Liu, Luyu Gao, Yuzhu Zhang, Jiang Yi. Improved chemical stability and cellular antioxidant activity of resveratrol in zein nanoparticle with bovine serum albumin-caffeic acid conjugate. Food chemistry. 2018 Sep; 261(?):283-291. doi: 10.1016/j.foodchem.2018.04.055. [PMID: 29739595]
  • Rui Tada, Daisuke Yamanaka, Miki Ogasawara, Momoko Saito, Naohito Ohno, Hiroshi Kiyono, Jun Kunisawa, Yukihiko Aramaki. Polymeric Caffeic Acid Is a Safer Mucosal Adjuvant That Augments Antigen-Specific Mucosal and Systemic Immune Responses in Mice. Molecular pharmaceutics. 2018 09; 15(9):4226-4234. doi: 10.1021/acs.molpharmaceut.8b00648. [PMID: 30107747]
  • Amany M Gad. Study on the influence of caffeic acid against sodium valproate-induced nephrotoxicity in rats. Journal of biochemical and molecular toxicology. 2018 Aug; 32(8):e22175. doi: 10.1002/jbt.22175. [PMID: 29968957]
  • Dragana Dekanski, Biljana Spremo-Potparević, Vladan Bajić, Lada Živković, Dijana Topalović, Dušan N Sredojević, Vesna Lazić, Jovan M Nedeljković. Acute toxicity study in mice of orally administrated TiO2 nanoparticles functionalized with caffeic acid. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2018 May; 115(?):42-48. doi: 10.1016/j.fct.2018.02.064. [PMID: 29510221]
  • Fauzia Yasir, Atia-Tul- Wahab, M Iqbal Choudhary. Protective effect of dietary polyphenol caffeic acid on ethylene glycol-induced kidney stones in rats. Urolithiasis. 2018 Apr; 46(2):157-166. doi: 10.1007/s00240-017-0982-1. [PMID: 28616648]
  • Pedram Shokouh, Per Bendix Jeppesen, Kjeld Hermansen, Natalja P Nørskov, Christoffer Laustsen, Stephen Jacques Hamilton-Dutoit, Haiyun Qi, Hans Stødkilde-Jørgensen, Søren Gregersen. A Combination of Coffee Compounds Shows Insulin-Sensitizing and Hepatoprotective Effects in a Rat Model of Diet-Induced Metabolic Syndrome. Nutrients. 2017 Dec; 10(1):. doi: 10.3390/nu10010006. [PMID: 29271886]
  • Bruna Aline Michelotto Cantelli, Tamires Aparecida Bitencourt, Tatiana Takahasi Komoto, Rene Oliveira Beleboni, Mozart Marins, Ana Lúcia Fachin. Caffeic acid and licochalcone A interfere with the glyoxylate cycle of Trichophyton rubrum. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2017 Dec; 96(?):1389-1394. doi: 10.1016/j.biopha.2017.11.051. [PMID: 29174577]
  • Daniela Moura de Oliveira, Geni Rodrigues Sampaio, Carolina Bonin Pinto, Rodrigo Ramos Catharino, Deborah H Markowicz Bastos. Bioavailability of chlorogenic acids in rats after acute ingestion of maté tea (Ilex paraguariensis) or 5-caffeoylquinic acid. European journal of nutrition. 2017 Dec; 56(8):2541-2556. doi: 10.1007/s00394-016-1290-1. [PMID: 27535559]
  • Yuan Gao, Shuai Ma, Meng Wang, Xiao-Yuan Feng. Characterization of Free, Conjugated, and Bound Phenolic Acids in Seven Commonly Consumed Vegetables. Molecules (Basel, Switzerland). 2017 Nov; 22(11):. doi: 10.3390/molecules22111878. [PMID: 29104269]
  • Syed Haris Omar, Philip G Kerr, Christopher J Scott, Adam S Hamlin, Hassan K Obied. Olive (Olea europaea L.) Biophenols: A Nutriceutical against Oxidative Stress in SH-SY5Y Cells. Molecules (Basel, Switzerland). 2017 Oct; 22(11):. doi: 10.3390/molecules22111858. [PMID: 29109370]
  • Snehasis Jana, Himanshu Rastogi. Effects of Caffeic Acid and Quercetin on In Vitro Permeability, Metabolism and In Vivo Pharmacokinetics of Melatonin in Rats: Potential for Herb-Drug Interaction. European journal of drug metabolism and pharmacokinetics. 2017 Oct; 42(5):781-791. doi: 10.1007/s13318-016-0393-7. [PMID: 28070878]
  • Naseer Ali Shah, Muhammad Rashid Khan, Dereje Nigussie. Phytochemical investigation and nephroprotective potential of Sida cordata in rat. BMC complementary and alternative medicine. 2017 Aug; 17(1):388. doi: 10.1186/s12906-017-1896-8. [PMID: 28778164]
  • Xiudan Hou, Xusheng Wang, Yingxin Sun, Licheng Wang, Yong Guo. Graphene oxide for solid-phase extraction of bioactive phenolic acids. Analytical and bioanalytical chemistry. 2017 May; 409(14):3541-3549. doi: 10.1007/s00216-017-0291-0. [PMID: 28401287]
  • Yuan-Yuan Cheng, Dan Luo, Zhengyuan Xia, Hung-Fat Tse, Xuechen Li, Jianhui Rong. In Vivo Cardioprotective Effects and Pharmacokinetic Profile of N-Propyl Caffeamide Against Ischemia Reperfusion Injury. Archivum immunologiae et therapiae experimentalis. 2017 Apr; 65(2):145-156. doi: 10.1007/s00005-016-0413-y. [PMID: 27480649]
  • Vanderson S Bispo, Lucas S Dantas, Adriano B Chaves, Isabella F D Pinto, Railmara P DA Silva, Felipe A M Otsuka, Rodrigo B Santos, Aline C Santos, Danielle J Trindade, Humberto R Matos. Reduction of the DNA damages, Hepatoprotective Effect and Antioxidant Potential of the Coconut Water, ascorbic and Caffeic Acids in Oxidative Stress Mediated by Ethanol. Anais da Academia Brasileira de Ciencias. 2017 Apr; 89(2):1095-1109. doi: 10.1590/0001-3765201720160581. [PMID: 28513780]
  • W Chaturi Prasadani, Chaturi M Senanayake, Nimanthi Jayathilaka, Sagarika Ekanayake, Kapila N Seneviratne. Effect of three edible oils on the intestinal absorption of caffeic acid: An in vivo and in vitro study. PloS one. 2017; 12(6):e0179292. doi: 10.1371/journal.pone.0179292. [PMID: 28617858]
  • Esmail Lutfi, Patrick J Babin, Joaquim Gutiérrez, Encarnación Capilla, Isabel Navarro. Caffeic acid and hydroxytyrosol have anti-obesogenic properties in zebrafish and rainbow trout models. PloS one. 2017; 12(6):e0178833. doi: 10.1371/journal.pone.0178833. [PMID: 28570659]
  • Chun Pang, Liang Shi, Yuchen Sheng, Zhiyong Zheng, Hai Wei, Zhengtao Wang, Lili Ji. Caffeic acid attenuated acetaminophen-induced hepatotoxicity by inhibiting ERK1/2-mediated early growth response-1 transcriptional activation. Chemico-biological interactions. 2016 Dec; 260(?):186-195. doi: 10.1016/j.cbi.2016.10.009. [PMID: 27720869]
  • Maryam Salami, Mehdi Rahimmalek, Mohammad Hossein Ehtemam. Inhibitory effect of different fennel (Foeniculum vulgare) samples and their phenolic compounds on formation of advanced glycation products and comparison of antimicrobial and antioxidant activities. Food chemistry. 2016 Dec; 213(?):196-205. doi: 10.1016/j.foodchem.2016.06.070. [PMID: 27451172]
  • Yuhong Xiang, Lili Duan, Qiang Ma, Zizheng Lv, Zhu Ruohua, Zhuoyong Zhang. Fluorescence spectroscopy and molecular simulation on the interaction of caffeic acid with human serum albumin. Luminescence : the journal of biological and chemical luminescence. 2016 Dec; 31(8):1496-1502. doi: 10.1002/bio.3135. [PMID: 27072745]
  • Sanchari Basu Mallik, Jayesh Mudgal, Madhavan Nampoothiri, Susan Hall, Shailendra Anoopkumar- Dukie, Gary Grant, C Mallikarjuna Rao, Devinder Arora. Caffeic acid attenuates lipopolysaccharide-induced sickness behaviour and neuroinflammation in mice. Neuroscience letters. 2016 Oct; 632(?):218-23. doi: 10.1016/j.neulet.2016.08.044. [PMID: 27597761]
  • Zhanli Liu, Xunyang Zheng, Yanlei Guo, Weihan Qin, Lei Hua, Yong Yang. Quantitatively metabolic profiles of salvianolic acids in rats after gastric-administration of Salvia miltiorrhiza extract. Fitoterapia. 2016 Sep; 113(?):27-34. doi: 10.1016/j.fitote.2016.06.017. [PMID: 27370098]
  • Shaoshan Mai, Qin He, Hong Wang, Xinyue Hu, Ying Luo, Yang Yang, Shengnan Kuang, Xiaoyan Tian, Jie Ma, Junqing Yang. 5-lipoxygenase activation is involved in the mechanisms of chronic hepatic injury in a rat model of chronic aluminum overload exposure. Toxicology and applied pharmacology. 2016 08; 305(?):259-266. doi: 10.1016/j.taap.2016.06.029. [PMID: 27368151]
  • Lingyu Zhou, Tianyu Zhang, Bin Lu, Zengyang Yu, Xiyu Mei, Palida Abulizi, Lili Ji. Lonicerae Japonicae Flos attenuates diabetic retinopathy by inhibiting retinal angiogenesis. Journal of ethnopharmacology. 2016 Aug; 189(?):117-25. doi: 10.1016/j.jep.2016.05.039. [PMID: 27196298]
  • Anna Zasowska-Nowak, Piotr J Nowak, Piotr Bialasiewicz, Anna Prymont-Przyminska, Anna Zwolinska, Agata Sarniak, Anna Wlodarczyk, Jaroslaw Markowski, Krzysztof P Rutkowski, Dariusz Nowak. Strawberries Added to the Usual Diet Suppress Fasting Plasma Paraoxonase Activity and Have a Weak Transient Decreasing Effect on Cholesterol Levels in Healthy Nonobese Subjects. Journal of the American College of Nutrition. 2016 07; 35(5):422-35. doi: 10.1080/07315724.2015.1065523. [PMID: 26934671]
  • A H Lee, L 'b Tan, N Hiramatsu, A Ishisaka, H Alfonso, A Tanaka, N Uemura, Y Fujiwara, R Takechi. Plasma concentrations of coffee polyphenols and plasma biomarkers of diabetes risk in healthy Japanese women. Nutrition & diabetes. 2016 Jun; 6(?):e212. doi: 10.1038/nutd.2016.19. [PMID: 27270110]
  • Ali Asghar Hatamnia, Arman Rostamzad, Parviz Malekzadeh, Reza Darvishzadeh, Nasser Abbaspour, Mohammadyar Hosseini, Khoshnood Nourollahi, Reza Sheikh Akbari Mehr. Antioxidant activity of different parts of Pistacia khinjuk Stocks fruit and its correlation to phenolic composition. Natural product research. 2016 Jun; 30(12):1445-50. doi: 10.1080/14786419.2015.1060593. [PMID: 26166043]
  • Zhan Zhang, Xinyue Wu, Shuyuan Cao, Li Wang, Di Wang, Hui Yang, Yiming Feng, Shoulin Wang, Lei Li. Caffeic acid ameliorates colitis in association with increased Akkermansia population in the gut microbiota of mice. Oncotarget. 2016 May; 7(22):31790-9. doi: 10.18632/oncotarget.9306. [PMID: 27177331]
  • Chunli Gan, Lu Liu, Yan Du, Liqian Wang, Mingjie Gao, Lijun Wu, Chunjuan Yang. Simultaneous determination and pharmacokinetic study of four phenol compounds in rat plasma by ultra-high performance liquid chromatography with tandem mass spectrometry after oral administration of Echinacea purpurea extract. Journal of separation science. 2016 May; 39(9):1628-37. doi: 10.1002/jssc.201600051. [PMID: 26924074]
  • Yoshiki Nimiya, Weicang Wang, Zheyuan Du, Elvira Sukamtoh, Julia Zhu, Eric Decker, Guodong Zhang. Redox modulation of curcumin stability: Redox active antioxidants increase chemical stability of curcumin. Molecular nutrition & food research. 2016 Mar; 60(3):487-94. doi: 10.1002/mnfr.201500681. [PMID: 26608515]
  • Gloria M Agudelo-Ochoa, Isabel C Pulgarín-Zapata, Claudia M Velásquez-Rodriguez, Mauricio Duque-Ramírez, Mauricio Naranjo-Cano, Mónica M Quintero-Ortiz, Oscar J Lara-Guzmán, Katalina Muñoz-Durango. Coffee Consumption Increases the Antioxidant Capacity of Plasma and Has No Effect on the Lipid Profile or Vascular Function in Healthy Adults in a Randomized Controlled Trial. The Journal of nutrition. 2016 Mar; 146(3):524-31. doi: 10.3945/jn.115.224774. [PMID: 26843588]
  • Rocío García-Villalba, Francisco A Tomás-Barberán, Pascale Fança-Berthon, Marc Roller, Pilar Zafrilla, Nicolas Issaly, María-Teresa García-Conesa. Targeted and Untargeted Metabolomics to Explore the Bioavailability of the Secoiridoids from a Seed/Fruit Extract (Fraxinus angustifolia Vahl) in Human Healthy Volunteers: A Preliminary Study. Molecules (Basel, Switzerland). 2015 Dec; 20(12):22202-19. doi: 10.3390/molecules201219845. [PMID: 26690403]
  • Annelies Breynaert, Douwina Bosscher, Ariane Kahnt, Magda Claeys, Paul Cos, Luc Pieters, Nina Hermans. Development and Validation of an in vitro Experimental GastroIntestinal Dialysis Model with Colon Phase to Study the Availability and Colonic Metabolisation of Polyphenolic Compounds. Planta medica. 2015 Aug; 81(12-13):1075-83. doi: 10.1055/s-0035-1546154. [PMID: 26166134]
  • Isabella F D Pinto, Railmara P Silva, Adriano de B Chaves Filho, Lucas S Dantas, Vanderson S Bispo, Isaac A Matos, Felipe A M Otsuka, Aline C Santos, Humberto Reis Matos. Study of Antiglycation, Hypoglycemic, and Nephroprotective Activities of the Green Dwarf Variety Coconut Water (Cocos nucifera L.) in Alloxan-Induced Diabetic Rats. Journal of medicinal food. 2015 Jul; 18(7):802-9. doi: 10.1089/jmf.2014.0046. [PMID: 25651375]
  • Qi Sun, Nicole M Wedick, Shelley S Tworoger, An Pan, Mary K Townsend, Aedin Cassidy, Adrian A Franke, Eric B Rimm, Frank B Hu, Rob M van Dam. Urinary Excretion of Select Dietary Polyphenol Metabolites Is Associated with a Lower Risk of Type 2 Diabetes in Proximate but Not Remote Follow-Up in a Prospective Investigation in 2 Cohorts of US Women. The Journal of nutrition. 2015 Jun; 145(6):1280-8. doi: 10.3945/jn.114.208736. [PMID: 25904735]
  • Xiangyang Wang, Wei Li, Xiaohui Ma, Yang Chu, Shuming Li, Jiahua Guo, Yumeng Jia, Shuiping Zhou, Yonghong Zhu, Changxiao Liu. Simultaneous determination of caffeic acid and its major pharmacologically active metabolites in rat plasma by LC-MS/MS and its application in pharmacokinetic study. Biomedical chromatography : BMC. 2015 Apr; 29(4):552-9. doi: 10.1002/bmc.3313. [PMID: 25164780]
  • Vishnu Vignesh Kanagaraj, Lakshmikanthan Panneerselvam, Vimal Govindarajan, Jaishabanu Ameeramja, Ekambaram Perumal. Caffeic acid, a phyto polyphenol mitigates fluoride induced hepatotoxicity in rats: A possible mechanism. BioFactors (Oxford, England). 2015 Mar; 41(2):90-100. doi: 10.1002/biof.1203. [PMID: 25845575]
  • Pei Wang, Huadong Chen, Yingdong Zhu, Jennifer McBride, Junsheng Fu, Shengmin Sang. Oat avenanthramide-C (2c) is biotransformed by mice and the human microbiota into bioactive metabolites. The Journal of nutrition. 2015 Feb; 145(2):239-45. doi: 10.3945/jn.114.206508. [PMID: 25644343]
  • Valentina Sinisi, Cristina Forzato, Nicola Cefarin, Luciano Navarini, Federico Berti. Interaction of chlorogenic acids and quinides from coffee with human serum albumin. Food chemistry. 2015 Feb; 168(?):332-40. doi: 10.1016/j.foodchem.2014.07.080. [PMID: 25172718]
  • Massimiliano Migliori, Vincenzo Cantaluppi, Claudio Mannari, Alberto A E Bertelli, Davide Medica, Alessandro Domenico Quercia, Victor Navarro, Alessia Scatena, Luca Giovannini, Luigi Biancone, Vincenzo Panichi. Caffeic acid, a phenol found in white wine, modulates endothelial nitric oxide production and protects from oxidative stress-associated endothelial cell injury. PloS one. 2015; 10(4):e0117530. doi: 10.1371/journal.pone.0117530. [PMID: 25853700]
  • Pamela Somers, Annelies Roosens, Filip De Somer, Maria Cornelissen, Guido Van Nooten. Non-Cytotoxic Crosslinkers for Heart Valve Tissue Engineering. The Journal of heart valve disease. 2015 Jan; 24(1):92-100. doi: . [PMID: 26182626]
  • Carlos A H Fernandes, Fábio Florença Cardoso, Walter G L Cavalcante, Andreimar M Soares, Maeli Dal-Pai, Marcia Gallacci, Marcos R M Fontes. Structural Basis for the Inhibition of a Phospholipase A2-Like Toxin by Caffeic and Aristolochic Acids. PloS one. 2015; 10(7):e0133370. doi: 10.1371/journal.pone.0133370. [PMID: 26192963]
  • Yuxin An, Qian Li, Jiejun Chen, Xiaokang Gao, Hongwei Chen, Chaoni Xiao, Liujiao Bian, Jianbin Zheng, Xinfeng Zhao, Xiaohui Zheng. Binding of caffeic acid to human serum albumin by the retention data and frontal analysis. Biomedical chromatography : BMC. 2014 Dec; 28(12):1881-6. doi: 10.1002/bmc.3238. [PMID: 24828401]
  • Shihua Xing, Ying Peng, Mengyue Wang, Daofeng Chen, Xiaobo Li. In vitro human fecal microbial metabolism of Forsythoside A and biological activities of its metabolites. Fitoterapia. 2014 Dec; 99(?):159-65. doi: 10.1016/j.fitote.2014.09.018. [PMID: 25281775]
  • Su-Jun Wang, Jie Zeng, Ben-Kun Yang, Yun-Ming Zhong. Bioavailability of caffeic acid in rats and its absorption properties in the Caco-2 cell model. Pharmaceutical biology. 2014 Sep; 52(9):1150-7. doi: 10.3109/13880209.2013.879906. [PMID: 24635458]
  • Angélique Stalmach, Gary Williamson, Alan Crozier. Impact of dose on the bioavailability of coffee chlorogenic acids in humans. Food & function. 2014 Aug; 5(8):1727-37. doi: 10.1039/c4fo00316k. [PMID: 24947504]
  • Wei Zhou, Jinjun Shan, Shouquan Wang, Wenzheng Ju, Minxin Meng, Baochang Cai, Liuqing Di. Simultaneous determination of caffeic acid derivatives by UPLC-MS/MS in rat plasma and its application in pharmacokinetic study after oral administration of Flos Lonicerae-Fructus Forsythiae herb combination. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2014 Feb; 949-950(?):7-15. doi: 10.1016/j.jchromb.2013.12.035. [PMID: 24441018]
  • Chongming Wu, Hong Luan, Xue Zhang, Shuai Wang, Xiaopo Zhang, Xiaobo Sun, Peng Guo. Chlorogenic acid protects against atherosclerosis in ApoE-/- mice and promotes cholesterol efflux from RAW264.7 macrophages. PloS one. 2014; 9(9):e95452. doi: 10.1371/journal.pone.0095452. [PMID: 25187964]
  • Chung-Chia Liao, Ting-Tsz Ou, Cheng-Hsun Wu, Chau-Jong Wang. Prevention of diet-induced hyperlipidemia and obesity by caffeic acid in C57BL/6 mice through regulation of hepatic lipogenesis gene expression. Journal of agricultural and food chemistry. 2013 Nov; 61(46):11082-8. doi: 10.1021/jf4026647. [PMID: 24156384]
  • Guo-Liang Dai, Shi-Tang Ma, Shi-Jia Liu, Xiao-Gui Cheng, Yu-Xin Zang, Wen-Zheng Ju, Heng-Shan Tan. [Study on determination of caffeic acid, chlorogenic acid in rat plasma and their pharmacokinetics with LC-MS/MS]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2013 Nov; 38(21):3753-7. doi: NULL. [PMID: 24494567]