L-Malate (BioDeep_00000897385)
代谢物信息卡片
L-Malate
化学式: C4H4O5-2 (132.0059)
中文名称:
谱图信息:
最多检出来源 Viridiplantae(plant) 94.74%
分子结构信息
SMILES: C(C(C(=O)[O-])O)C(=O)[O-]
InChI: InChI=1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/p-2/t2-/m0/s1
相关代谢途径
Reactome(18)
- Metabolism
- Amino acid and derivative metabolism
- Metabolism of lipids
- Transport of small molecules
- SLC-mediated transmembrane transport
- Transport of inorganic cations/anions and amino acids/oligopeptides
- Fatty acid metabolism
- The tricarboxylic acid cycle
- Carbohydrate metabolism
- Glucose metabolism
- Fatty acyl-CoA biosynthesis
- The citric acid (TCA) cycle and respiratory electron transport
- Pyruvate metabolism and Citric Acid (TCA) cycle
- Citric acid cycle (TCA cycle)
- Sulfur amino acid metabolism
- Degradation of cysteine and homocysteine
- Gluconeogenesis
- Lipid metabolism
BioCyc(30)
- anaerobic energy metabolism (invertebrates, mitochondrial)
- superpathway of anaerobic energy metabolism (invertebrates)
- superpathway of glycol metabolism and degradation
- superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle
- glycolate and glyoxylate degradation II
- formaldehyde assimilation I (serine pathway)
- superpathway of pentose and pentitol degradation
- chitin degradation to ethanol
- superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass
- TCA cycle I (prokaryotic)
- mixed acid fermentation
- superpathway of glyoxylate bypass and TCA
- superpathway of central carbon metabolism
- gluconeogenesis I
- TCA cycle VI (obligate autotrophs)
- Methanobacterium thermoautotrophicum biosynthetic metabolism
- ethylmalonyl-CoA pathway
- methylaspartate cycle
- crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (engineered)
- TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)
- L-malate degradation I
- L-carnitine degradation III
- reductive TCA cycle I
- anaerobic energy metabolism (invertebrates, cytosol)
- L-malate degradation II
- C4 photosynthetic carbon assimilation cycle, NAD-ME type
- superpathway of glycolysis, pyruvate dehydrogenase and TCA cycle
- superpathway of glyoxylate cycle
- respiration (anaerobic)
- oxaloacetate degradation to pyruvate
PlantCyc(4)
代谢反应
110 个相关的代谢反应过程信息。
Reactome(58)
- Metabolism:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA - The citric acid (TCA) cycle and respiratory electron transport:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Pyruvate metabolism and Citric Acid (TCA) cycle:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Citric acid cycle (TCA cycle):
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Metabolism:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA - The citric acid (TCA) cycle and respiratory electron transport:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Pyruvate metabolism and Citric Acid (TCA) cycle:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Citric acid cycle (TCA cycle):
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - The citric acid (TCA) cycle and respiratory electron transport:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Pyruvate metabolism and Citric Acid (TCA) cycle:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Citric acid cycle (TCA cycle):
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - The citric acid (TCA) cycle and respiratory electron transport:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Pyruvate metabolism and Citric Acid (TCA) cycle:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Citric acid cycle (TCA cycle):
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - The citric acid (TCA) cycle and respiratory electron transport:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Pyruvate metabolism and Citric Acid (TCA) cycle:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Citric acid cycle (TCA cycle):
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - The citric acid (TCA) cycle and respiratory electron transport:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Pyruvate metabolism and Citric Acid (TCA) cycle:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Citric acid cycle (TCA cycle):
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Metabolism:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA - The citric acid (TCA) cycle and respiratory electron transport:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Pyruvate metabolism and Citric Acid (TCA) cycle:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Citric acid cycle (TCA cycle):
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - The citric acid (TCA) cycle and respiratory electron transport:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Pyruvate metabolism and Citric Acid (TCA) cycle:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Citric acid cycle (TCA cycle):
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - The citric acid (TCA) cycle and respiratory electron transport:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Pyruvate metabolism and Citric Acid (TCA) cycle:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Citric acid cycle (TCA cycle):
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Metabolism:
ATP + PROP-CoA + carbon dioxide ⟶ ADP + MEMA-CoA + Pi - The citric acid (TCA) cycle and respiratory electron transport:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Pyruvate metabolism and Citric Acid (TCA) cycle:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Citric acid cycle (TCA cycle):
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - The citric acid (TCA) cycle and respiratory electron transport:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Pyruvate metabolism and Citric Acid (TCA) cycle:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Citric acid cycle (TCA cycle):
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Metabolism:
ATP + PROP-CoA + carbon dioxide ⟶ ADP + MEMA-CoA + Pi - The citric acid (TCA) cycle and respiratory electron transport:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Pyruvate metabolism and Citric Acid (TCA) cycle:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Citric acid cycle (TCA cycle):
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Metabolism:
H2O + PBG ⟶ HMBL + ammonia - The tricarboxylic acid cycle:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Metabolism:
CAR + propionyl CoA ⟶ CoA-SH + Propionylcarnitine - The citric acid (TCA) cycle and respiratory electron transport:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Pyruvate metabolism and Citric Acid (TCA) cycle:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Citric acid cycle (TCA cycle):
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Metabolism:
GAA + SAM ⟶ CRET + H+ + SAH - The citric acid (TCA) cycle and respiratory electron transport:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Pyruvate metabolism and Citric Acid (TCA) cycle:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Citric acid cycle (TCA cycle):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
BioCyc(29)
- superpathway of glyoxylate cycle:
ATP + a fatty acid + coenzyme A ⟶ AMP + H+ + a 2,3,4-saturated fatty acyl CoA + diphosphate - glyoxylate cycle:
H2O + acetyl-CoA + glyoxylate ⟶ (S)-malate + H+ + coenzyme A - superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass:
ATP + H2O + pyruvate ⟶ AMP + H+ + phosphate + phosphoenolpyruvate - superpathway of glyoxylate bypass and TCA:
2-oxoglutarate + NAD+ + coenzyme A ⟶ CO2 + NADH + succinyl-CoA - formaldehyde assimilation I (serine pathway):
L-malyl-CoA ⟶ acetyl-CoA + glyoxylate - sinapate ester biosynthesis:
1-O-sinapoyl-β-D-glucose + choline ⟶ O-sinapoylcholine + D-glucopyranose - sinapate ester biosynthesis:
1-O-sinapoyl-β-D-glucose + choline ⟶ O-sinapoylcholine + D-glucopyranose - TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase):
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - L-malate degradation I:
(S)-malate + H+ ⟶ (S)-lactate + CO2 - L-carnitine degradation III:
H+ + L-carnitine + NAD(P)H + O2 ⟶ H2O + L-malic semialdehyde + NAD(P)+ + trimethylamine - anaerobic energy metabolism (invertebrates, mitochondrial):
ATP + hydrogencarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - superpathway of anaerobic energy metabolism (invertebrates):
ATP + hydrogencarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - gluconeogenesis I:
β-D-fructose 1,6-bisphosphate ⟶ D-glyceraldehyde 3-phosphate + DHAP - L-malate degradation II:
(S)-malate + NAD+ ⟶ CO2 + NADH + pyruvate - C4 photosynthetic carbon assimilation cycle, NAD-ME type:
H+ + hydrogencarbonate ⟶ CO2 + H2O - gluconeogenesis I:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - aspartate degradation II:
2-oxoglutarate + asp ⟶ glt + oxaloacetate - respiration (anaerobic):
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - pyruvate fermentation to propionate I:
(S)-methylmalonyl-CoA + pyruvate ⟶ oxaloacetate + propanoyl-CoA - TCA cycle:
2-oxoglutarate + NAD+ + coenzyme A ⟶ CO2 + NADH + succinyl-CoA - gluconeogenesis I:
ATP + H2O + pyruvate ⟶ AMP + H+ + phosphate + phosphoenolpyruvate - gluconeogenesis I:
ATP + H2O + pyruvate ⟶ AMP + H+ + phosphate + phosphoenolpyruvate - oxaloacetate degradation to pyruvate:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - succinic fermentation pathway:
(S)-malate ⟶ H2O + fumarate - superpathway of central carbon metabolism:
ATP + H2O + pyruvate ⟶ AMP + H+ + phosphate + phosphoenolpyruvate - respiration (anaerobic):
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - TCA cycle:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - superpathway of glycolysis, pyruvate dehydrogenase and TCA cycle:
ATP + H2O + pyruvate ⟶ AMP + H+ + phosphate + phosphoenolpyruvate - formaldehyde assimilation I (serine pathway):
H+ + oxaloacetate + phosphate ⟶ CO2 + H2O + phosphoenolpyruvate
Plant Reactome(3)
- Metabolism and regulation:
ATP + CoA + propionate ⟶ AMP + PPi + PROP-CoA - Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
INOH(0)
PlantCyc(19)
- phaselate biosynthesis:
(S)-malate + trans-caffeoyl-CoA ⟶ coenzyme A + phaselate - phaselate biosynthesis:
4-coumarate + ATP + coenzyme A ⟶ (E)-4-coumaroyl-CoA + AMP + diphosphate - phaselate biosynthesis:
4-coumarate + ATP + coenzyme A ⟶ (E)-4-coumaroyl-CoA + AMP + diphosphate - sinapate ester biosynthesis:
1-O-sinapoyl-β-D-glucose + choline ⟶ O-sinapoylcholine + D-glucopyranose - sinapate ester biosynthesis:
(S)-malate + 1-O-sinapoyl-β-D-glucose ⟶ D-glucopyranose + sinapoyl-(S)-malate - sinapate ester biosynthesis:
O-sinapoylcholine + H2O ⟶ H+ + choline + sinapate - sinapate ester biosynthesis:
1-O-sinapoyl-β-D-glucose ⟶ 1,2-di-O-sinapoyl-β-D-glucose + D-glucopyranose - sinapate ester biosynthesis:
(S)-malate + 1-O-sinapoyl-β-D-glucose ⟶ D-glucopyranose + sinapoyl-(S)-malate - sinapate ester biosynthesis:
1-O-sinapoyl-β-D-glucose + choline ⟶ O-sinapoylcholine + D-glucopyranose - sinapate ester biosynthesis:
1-O-sinapoyl-β-D-glucose + choline ⟶ O-sinapoylcholine + D-glucopyranose - sinapate ester biosynthesis:
1-O-sinapoyl-β-D-glucose + choline ⟶ O-sinapoylcholine + D-glucopyranose - sinapate ester biosynthesis:
1-O-sinapoyl-β-D-glucose ⟶ 1,2-di-O-sinapoyl-β-D-glucose + D-glucopyranose - sinapate ester biosynthesis:
1-O-sinapoyl-β-D-glucose + choline ⟶ O-sinapoylcholine + D-glucopyranose - sinapate ester biosynthesis:
1-O-sinapoyl-β-D-glucose + choline ⟶ O-sinapoylcholine + D-glucopyranose - sinapate ester biosynthesis:
O-sinapoylcholine + H2O ⟶ H+ + choline + sinapate - sinapate ester biosynthesis:
(S)-malate + 1-O-sinapoyl-β-D-glucose ⟶ D-glucopyranose + sinapoyl-(S)-malate - sinapate ester biosynthesis:
(S)-malate + 1-O-sinapoyl-β-D-glucose ⟶ D-glucopyranose + sinapoyl-(S)-malate - sinapate ester biosynthesis:
O-sinapoylcholine + H2O ⟶ H+ + choline + sinapate - C4 photosynthetic carbon assimilation cycle, NAD-ME type:
H+ + hydrogencarbonate ⟶ CO2 + H2O
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PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
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