Serotonin(1+) (BioDeep_00000897293)
代谢物信息卡片
Serotonin(1+)
化学式: C10H13N2O+ (177.1028)
中文名称:
谱图信息:
最多检出来源 Viridiplantae(plant) 58.72%
分子结构信息
SMILES: C1=CC2=C(C=C1O)C(=CN2)CC[NH3+]
InChI: InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2/p+1
描述信息
An ammonium ion that is the conjugate acid of serotonin; major species at pH 7.3.
COVID info from COVID-19 Disease Map
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(25)
- Metabolism
- Biological oxidations
- Phase I - Functionalization of compounds
- Disease
- Amino acid and derivative metabolism
- Diseases of metabolism
- Transport of small molecules
- SLC-mediated transmembrane transport
- Transport of bile salts and organic acids, metal ions and amine compounds
- Signaling Pathways
- Amine Oxidase reactions
- Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB
- Neuronal System
- Transmission across Chemical Synapses
- Neurotransmitter release cycle
- Neurotransmitter clearance
- Signaling by GPCR
- GPCR ligand binding
- Class A/1 (Rhodopsin-like receptors)
- GPCR downstream signalling
- G alpha (i) signalling events
- Clearance of seratonin
- Metabolism of serotonin
- Metabolic disorders of biological oxidation enzymes
- Metabolism of amine-derived hormones
PlantCyc(0)
代谢反应
141 个相关的代谢反应过程信息。
Reactome(129)
- Signaling Pathways:
ADORA2A,B + Ade-Rib ⟶ ADORA2A,B:Ade-Rib - Signaling by GPCR:
ADORA2A,B + Ade-Rib ⟶ ADORA2A,B:Ade-Rib - GPCR downstream signalling:
H2O + cAMP ⟶ AMP - G alpha (q) signalling events:
GTP + Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) ⟶ GDP + Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) - Signaling Pathways:
AcK685- p-Y705,S727-STAT3 dimer + H2O ⟶ CH3COO- + p-Y705,S727-STAT3 dimer - Signaling by GPCR:
Ade-Rib ⟶ ADORA2A,B:Ade-Rib - GPCR downstream signalling:
Heterotrimeric G-protein Gi (inactive) + Ligand:GPCR complexes that activate Gi ⟶ Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) - G alpha (q) signalling events:
Heterotrimeric G-protein Gq/11 (inactive) + Ligand:GPCR complexes that activate Gq/11 ⟶ Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) - Signaling Pathways:
AcK685- p-Y705,S727-STAT3 dimer + H2O ⟶ CH3COO- + p-Y705,S727-STAT3 dimer - Signaling by GPCR:
ADORA1,3 + Ade-Rib ⟶ ADORA1,3:Ade-Rib - GPCR downstream signalling:
Heterotrimeric G-protein Gi (inactive) + Ligand:GPCR complexes that activate Gi ⟶ Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) - G alpha (q) signalling events:
Heterotrimeric G-protein Gq/11 (inactive) + Ligand:GPCR complexes that activate Gq/11 ⟶ Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) - Signaling Pathways:
AcK685- p-Y705,S727-STAT3 dimer + H2O ⟶ CH3COO- + p-Y705,S727-STAT3 dimer - Signaling by GPCR:
Ade-Rib ⟶ ADORA1,3:Ade-Rib - Signaling Pathways:
AcK685- p-Y705,S727-STAT3 dimer + H2O ⟶ CH3COO- + p-Y705,S727-STAT3 dimer - Signaling by GPCR:
Ade-Rib + AdoR ⟶ ADORA1,3:Ade-Rib - GPCR downstream signalling:
Heterotrimeric G-protein Gi (inactive) + Ligand:GPCR complexes that activate Gi ⟶ Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) - G alpha (q) signalling events:
Heterotrimeric G-protein Gq/11 (inactive) + Ligand:GPCR complexes that activate Gq/11 ⟶ Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) - Signaling Pathways:
AcK685- p-Y705,S727-STAT3 dimer + H2O ⟶ CH3COO- + p-Y705,S727-STAT3 dimer - Signaling by GPCR:
ADORA1,3 + Ade-Rib ⟶ ADORA1,3:Ade-Rib - GPCR downstream signalling:
Heterotrimeric G-protein Gi (inactive) + Ligand:GPCR complexes that activate Gi ⟶ Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) - G alpha (q) signalling events:
GTP + Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) ⟶ GDP + Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) - Signaling Pathways:
AcK685- p-Y705,S727-STAT3 dimer + H2O ⟶ CH3COO- + p-Y705,S727-STAT3 dimer - Signaling by GPCR:
ADORA1,3 + Ade-Rib ⟶ ADORA1,3:Ade-Rib - GPCR downstream signalling:
Heterotrimeric G-protein Gi (inactive) + Ligand:GPCR complexes that activate Gi ⟶ Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) - G alpha (q) signalling events:
Heterotrimeric G-protein Gq/11 (inactive) + Ligand:GPCR complexes that activate Gq/11 ⟶ Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) - Signaling Pathways:
AcK685- p-Y705,S727-STAT3 dimer + H2O ⟶ CH3COO- + p-Y705,S727-STAT3 dimer - Signaling by GPCR:
ADORA2A,B + Ade-Rib ⟶ ADORA2A,B:Ade-Rib - GPCR downstream signalling:
Heterotrimeric G-protein Gi (inactive) + Ligand:GPCR complexes that activate Gi ⟶ Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) - G alpha (q) signalling events:
Heterotrimeric G-protein Gq/11 (inactive) + Ligand:GPCR complexes that activate Gq/11 ⟶ Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) - Signaling Pathways:
AcK685- p-Y705,S727-STAT3 dimer + H2O ⟶ CH3COO- + p-Y705,S727-STAT3 dimer - Signaling by GPCR:
ADORA1,3 + Ade-Rib ⟶ ADORA1,3:Ade-Rib - Signaling Pathways:
AcK685- p-Y705,S727-STAT3 dimer + H2O ⟶ CH3COO- + p-Y705,S727-STAT3 dimer - Signaling by GPCR:
ADORA1,3 + Ade-Rib ⟶ ADORA1,3:Ade-Rib - GPCR downstream signalling:
Heterotrimeric G-protein Gi (inactive) + Ligand:GPCR complexes that activate Gi ⟶ Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) - G alpha (q) signalling events:
Heterotrimeric G-protein Gq/11 (inactive) + Ligand:GPCR complexes that activate Gq/11 ⟶ Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) - G alpha (i) signalling events:
ATP ⟶ PPi + cAMP - G alpha (i) signalling events:
Heterotrimeric G-protein Gi (inactive) + Ligand:GPCR complexes that activate Gi ⟶ Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) - G alpha (i) signalling events:
Heterotrimeric G-protein Gi (inactive) + Ligand:GPCR complexes that activate Gi ⟶ Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) - G alpha (i) signalling events:
Heterotrimeric G-protein Gi (inactive) + Ligand:GPCR complexes that activate Gi ⟶ Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) - G alpha (i) signalling events:
Heterotrimeric G-protein Gi (inactive) + Ligand:GPCR complexes that activate Gi ⟶ Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) - Signaling Pathways:
AcK685- p-Y705,S727-STAT3 dimer + H2O ⟶ CH3COO- + p-Y705,S727-STAT3 dimer - Signaling by GPCR:
ADORA1,3 + Ade-Rib ⟶ ADORA1,3:Ade-Rib - GPCR downstream signalling:
PKA tetramer + cAMP ⟶ PKA tetramer:4xcAMP - G alpha (q) signalling events:
GTP + Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) ⟶ GDP + Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) - Metabolism:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA - Biological oxidations:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN - Phase I - Functionalization of compounds:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN - Amine Oxidase reactions:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Neuronal System:
DA + SAM ⟶ 3MT + SAH - Transmission across Chemical Synapses:
DA + SAM ⟶ 3MT + SAH - Neurotransmitter clearance:
DA + SAM ⟶ 3MT + SAH - Clearance of seratonin:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Metabolism of serotonin:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Neuronal System:
DA + SAM ⟶ 3MT + SAH - Transmission across Chemical Synapses:
DA + SAM ⟶ 3MT + SAH - Neurotransmitter clearance:
DA + SAM ⟶ 3MT + SAH - Clearance of seratonin:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Metabolism of serotonin:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Biological oxidations:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN - Phase I - Functionalization of compounds:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN - Amine Oxidase reactions:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Metabolism:
ATP + PROP-CoA + carbon dioxide ⟶ ADP + MEMA-CoA + Pi - Biological oxidations:
H+ + Oxygen + TPNH + aflatoxin B1 ⟶ AFXBO + H2O + TPN - Phase I - Functionalization of compounds:
CH3CHO + H2O + NAD ⟶ CH3COO- + H+ + NADH - Amine Oxidase reactions:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Neuronal System:
3MT + H2O + Oxygen ⟶ H2O2 + HVA + ammonia - Transmission across Chemical Synapses:
3MT + H2O + Oxygen ⟶ H2O2 + HVA + ammonia - Neurotransmitter clearance:
3MT + H2O + Oxygen ⟶ H2O2 + HVA + ammonia - Clearance of seratonin:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Metabolism of serotonin:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Neuronal System:
DA + SAM ⟶ 3MT + SAH - Transmission across Chemical Synapses:
DA + SAM ⟶ 3MT + SAH - Neurotransmitter clearance:
DA + SAM ⟶ 3MT + SAH - Clearance of seratonin:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Metabolism of serotonin:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Biological oxidations:
H+ + Oxygen + TPNH + progesterone ⟶ 11DCORST + H2O + TPN - Phase I - Functionalization of compounds:
H+ + Oxygen + TPNH + progesterone ⟶ 11DCORST + H2O + TPN - Amine Oxidase reactions:
H2O + Oxygen + TYR ⟶ H2O2 + HPHAC + ammonia - Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB:
H2O + Oxygen + TYR ⟶ H2O2 + HPHAC + ammonia - Metabolism:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA - Biological oxidations:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN - Phase I - Functionalization of compounds:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN - Amine Oxidase reactions:
H2O + Oxygen + TYR ⟶ H2O2 + HPHAC + ammonia - Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB:
H2O + Oxygen + TYR ⟶ H2O2 + HPHAC + ammonia - Neuronal System:
DA + SAM ⟶ 3MT + SAH - Transmission across Chemical Synapses:
DA + SAM ⟶ 3MT + SAH - Neurotransmitter clearance:
DA + SAM ⟶ 3MT + SAH - Clearance of seratonin:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Metabolism of serotonin:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Biological oxidations:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN - Phase I - Functionalization of compounds:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN - Amine Oxidase reactions:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Neuronal System:
DA + SAM ⟶ 3MT + SAH - Transmission across Chemical Synapses:
DA + SAM ⟶ 3MT + SAH - Neurotransmitter clearance:
DA + SAM ⟶ 3MT + SAH - Clearance of seratonin:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Metabolism of serotonin:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Biological oxidations:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN - Phase I - Functionalization of compounds:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN - Amine Oxidase reactions:
H2O + Oxygen + TYR ⟶ H2O2 + HPHAC + ammonia - Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB:
H2O + Oxygen + TYR ⟶ H2O2 + HPHAC + ammonia - Neuronal System:
DA + SAM ⟶ 3MT + SAH - Transmission across Chemical Synapses:
DA + SAM ⟶ 3MT + SAH - Neurotransmitter clearance:
DA + SAM ⟶ 3MT + SAH - Clearance of seratonin:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Metabolism of serotonin:
5HT + H2O + Oxygen ⟶ 5HIALD + H2O2 + ammonia - Metabolism:
ATP + PROP-CoA + carbon dioxide ⟶ ADP + MEMA-CoA + Pi - Biological oxidations:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN - Phase I - Functionalization of compounds:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN - Amine Oxidase reactions:
H2O + Oxygen + TYR ⟶ H2O2 + HPHAC + ammonia - Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB:
H2O + Oxygen + TYR ⟶ H2O2 + HPHAC + ammonia - Neuronal System:
DA + SAM ⟶ 3MT + SAH - Transmission across Chemical Synapses:
DA + SAM ⟶ 3MT + SAH - Neurotransmitter clearance:
DA + SAM ⟶ 3MT + SAH - Clearance of seratonin:
HIALD + NAD ⟶ H+ + HIAA + NADH - Metabolism of serotonin:
HIALD + NAD ⟶ H+ + HIAA + NADH - G alpha (i) signalling events:
Heterotrimeric G-protein Gi (inactive) + Ligand:GPCR complexes that activate Gi ⟶ Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) - G alpha (i) signalling events:
PKA tetramer + cAMP ⟶ PKA tetramer:4xcAMP - G alpha (i) signalling events:
Heterotrimeric G-protein Gi (inactive) + Ligand:GPCR complexes that activate Gi ⟶ Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) - G alpha (i) signalling events:
Heterotrimeric G-protein Gi (inactive) + Ligand:GPCR complexes that activate Gi ⟶ Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive)
BioCyc(5)
- superpathway of tryptophan utilization:
N-formylkynurenine + H2O ⟶ H+ + L-kynurenine + formate - serotonin degradation:
H2O + O2 + serotonin ⟶ 5-hydroxyindole acetaldehyde + ammonium + hydrogen peroxide - serotonin degradation:
5-hydroxytryptophol + NAD+ ⟶ 5-hydroxyindole acetaldehyde + H+ + NADH - serotonin degradation:
H2O + O2 + serotonin ⟶ 5-hydroxyindole acetaldehyde + H+ + ammonia + hydrogen peroxide - hydroxycinnamic acid serotonin amides biosynthesis:
trans-feruloyl-CoA + serotonin ⟶ H+ + coenzyme A + feruloylserotonin
WikiPathways(0)
Plant Reactome(3)
- Metabolism and regulation:
ATP + CoA + propionate ⟶ AMP + PPi + PROP-CoA - Secondary metabolism:
GPP + H2O ⟶ PPi + geraniol - Serotonin biosynthesis:
H+ + NAD(P)H + Oxygen + tryptamine ⟶ 5HT + NAD(P)+ + dihydrogen
INOH(0)
PlantCyc(3)
- hydroxycinnamic acid serotonin amides biosynthesis:
H+ + trp ⟶ CO2 + tryptamine - hydroxycinnamic acid serotonin amides biosynthesis:
H+ + trp ⟶ CO2 + tryptamine - hydroxycinnamic acid serotonin amides biosynthesis:
trans-feruloyl-CoA + serotonin ⟶ H+ + coenzyme A + feruloylserotonin
COVID-19 Disease Map(1)
- @COVID-19 Disease
Map["name"]:
2-Methyl-3-acetoacetyl-CoA + Coenzyme A ⟶ Acetyl-CoA + Propanoyl-CoA
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
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