Cefepime conjugate acid (BioDeep_00000897284)
代谢物信息卡片
化学式: C19H25N6O5S2+ (481.13277800000003)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C[N+]1(CCCC1)CC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)O
InChI: InChI=1S/C19H24N6O5S2/c1-25(5-3-4-6-25)7-10-8-31-17-13(16(27)24(17)14(10)18(28)29)22-15(26)12(23-30-2)11-9-32-19(20)21-11/h9,13,17H,3-8H2,1-2H3,(H3-,20,21,22,26,28,29)/p+1/b23-12-/t13-,17-/m1/s1
描述信息
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01D - Other beta-lactam antibacterials > J01DE - Fourth-generation cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Gisele Canan-Rochenbach, Marco A B Barreiros, André O S Lima, Pascale Bauda, Eric Sanches-Simões, Wendell Pimentel-Almeida, Rafael Ariente-Neto, Cleder A Somensi, Tito C M Almeida, Rogério Corrêa, Claudemir M Radetski. Characterization of bacterial resistance in treated hospital wastewater.
Environmental technology.
2024 Jan; 45(1):120-128. doi:
10.1080/09593330.2022.2100282. [PMID: 35802062] - Jiaojiao Fu, Fangting He, Jinming Xiao, Zhengyue Liao, Liying He, Jing He, Jinlin Guo, Sijing Liu. Rapid AMR prediction in Pseudomonas aeruginosa combining MALDI-TOF MS with DNN model.
Journal of applied microbiology.
2023 Nov; 134(11):. doi:
10.1093/jambio/lxad248. [PMID: 37930836] - Muriel Masi, Julia Vergalli, Ishan Ghai, Andrea Barba-Bon, Thérèse Schembri, Werner M Nau, Daniel Lafitte, Mathias Winterhalter, Jean-Marie Pagès. Cephalosporin translocation across enterobacterial OmpF and OmpC channels, a filter across the outer membrane.
Communications biology.
2022 10; 5(1):1059. doi:
10.1038/s42003-022-04035-y. [PMID: 36198902] - Mohamed Aboubakr, Afaf Abdelkader, Ola A Habotta, Nisreen Adel, Mahmoud A Emam, Ehab Y Abdelhiee, Obeid Shanab, Khaled Shoghy, Heba Elnoury, Mohamed M Soliman, Samah F Ibrahim, Ahmed Abdeen. Cefepime and diclofenac sodium combined treatment-potentiated multiple organ injury: Role of oxidative damage and disrupted lipid metabolism.
Journal of biochemical and molecular toxicology.
2021 Dec; 35(12):e22929. doi:
10.1002/jbt.22929. [PMID: 34676623] - Xiaocong Liu, Qingfan Wei, Xiaowei Yang, Xiaojie Wang, Jiamei Zhang, Rui Xu, Haoluo Zhang, Shaomin Wang, Xuemei Wan, Linhong Jiang, Yuman He, Shu Li, Rong Chen, Yonghai Wang, Yaxing Chen, Feng Qin, Yuanyuan Chen, Yanping Dai, Hongchun Li, Ying Zhao, Huaqin Zhang, Qian Bu, Hongbo Wang, Jingwei Tian, Yinglan Zhao, Xiaobo Cen. Lipidomics Reveals Dysregulated Glycerophospholipid Metabolism in the Corpus Striatum of Mice Treated with Cefepime.
ACS chemical neuroscience.
2021 12; 12(23):4449-4464. doi:
10.1021/acschemneuro.1c00608. [PMID: 34762393] - Xiaojiong Jia, Weijia Ma, Jianchun He, Xiaolang Tian, Hang Liu, Hua Zou, Si Cheng. Heteroresistance to cefepime in Pseudomonas aeruginosa bacteraemia.
International journal of antimicrobial agents.
2020 Mar; 55(3):105832. doi:
10.1016/j.ijantimicag.2019.10.013. [PMID: 31669739] - Edyta Konecka, Joanna Mokracka, Sylwia Krzymińska, Adam Kaznowski. Evaluation of The Pathogenic Potential of Insecticidal Serratia marcescens Strains to Humans.
Polish journal of microbiology.
2019; 68(2):185-191. doi:
10.21307/pjm-2019-018. [PMID: 31257791] - Supriya Ponnapula, Joseph M Swanson, G Christopher Wood, Bradley A Boucher, Diana L Wells, Martin A Croce, Timothy C Fabian. Treatment of Rhizobium radiobacter bacteremia in a critically ill trauma patient.
The Annals of pharmacotherapy.
2013 Nov; 47(11):1584-7. doi:
10.1177/1060028013500942. [PMID: 24259594] - V V Shepelevich, E A Kiprianova, L V Iaroshenko, L V Avdeeva. [Sensitivity of Pseudomonas chlororaphis to antibiotics and chemical tools of plant protection].
Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993).
2012 Nov; 74(6):24-8. doi:
". [PMID: 23293823] - Ilkay Erdogan Orhan, Berrin Ozcelik, Yüksel Kan, Murat Kartal. Inhibitory effects of various essential oils and individual components against extended-spectrum beta-lactamase (ESBL) produced by Klebsiella pneumoniae and their chemical compositions.
Journal of food science.
2011 Oct; 76(8):M538-46. doi:
10.1111/j.1750-3841.2011.02363.x. [PMID: 22417594] - Wipa Suginta, Kozhinjampara R Mahendran, Watcharin Chumjan, Eric Hajjar, Albert Schulte, Mathias Winterhalter, Helge Weingart. Molecular analysis of antimicrobial agent translocation through the membrane porin BpsOmp38 from an ultraresistant Burkholderia pseudomallei strain.
Biochimica et biophysica acta.
2011 Jun; 1808(6):1552-9. doi:
10.1016/j.bbamem.2010.10.018. [PMID: 21078354] - V K Dwivedi, A Soni, M Chaudhary, C P Singh, S M Shrivastava. Fixed-dose combination of cefepime plus amikacin (potentox) inhibits pneumonia infection.
Experimental lung research.
2009 Sep; 35(7):621-9. doi:
10.1080/01902140902833269. [PMID: 19842849] - Manu Chaudhary, Arvind Soni, Vivek Kumar Dwivedi. Fixed dose combination of cefepime plus amikacin prevent oxidative stress in liver of Mus musculus mice.
Current clinical pharmacology.
2008 Sep; 3(3):211-4. doi:
10.2174/157488408785747683. [PMID: 18781908] - Jérôme Bredin, Nathalie Saint, Monique Malléa, Emmanuelle Dé, Gérard Molle, Jean-Marie Pagès, Valérie Simonet. Alteration of pore properties of Escherichia coli OmpF induced by mutation of key residues in anti-loop 3 region.
The Biochemical journal.
2002 May; 363(Pt 3):521-8. doi:
10.1042/0264-6021:3630521. [PMID: 11964152]