GDP-Glucose (BioDeep_00000897221)

Main id: BioDeep_00000014486

 

PANOMIX_OTCML-2023


代谢物信息卡片


[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] hydrogen phosphate

  化学式: C16H25N5O16P2 (605.0772)
中文名称: 鸟苷酸二磷酸葡萄糖
  谱图信息: 最多检出来源 () %

分子结构信息

SMILES: C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)OP(=O)(O)OP(=O)(O)OC[C@@H]1[C@H]([C@H]([C@H](n2cnc3c2nc(N)[nH]c3=O)O1)O)O)O)O)O)O
InChI: InChI=1S/C16H25N5O16P2/c17-16-19-12-6(13(28)20-16)18-3-21(12)14-10(26)8(24)5(34-14)2-33-38(29,30)37-39(31,32)36-15-11(27)9(25)7(23)4(1-22)35-15/h3-5,7-11,14-15,22-27H,1-2H2,(H,29,30)(H,31,32)(H3,17,19,20,28)/t4-,5-,7-,8-,9+,10-,11-,14-,15-/m1/s1


描述信息

同义名列表

34 个代谢物同义名

GDP-Glucose; (((2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl)methoxy-hydroxyphosphoryl) ((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl) hydrogen phosphate; (((2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl)methoxy)(((hydroxy((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxy))phosphoryl)oxy))phosphinic acid; (GDP-Glc)1; [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl dihydrogen diphosphate (non-preferred name); [[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] hydrogen phosphate; {[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[hydroxy({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy})phosphoryl]oxy})phosphinic acid; GDG; Gdp glucose; GDP-a-D-Glucose; GDP-alpha-D-glucose; GDP-alpha-delta-glucose; GDP-I+--D-glucose; GDPG; Guanosine 5-(trihydrogen diphosphate); Guanosine 5-pyrophosphate; guanosine 5'-(3-(alpha-D-glucopyranosyl) dihydrogen diphosphate); Guanosine 5'-(trihydrogen diphosphate), P'-a-D-glucopyranosyl ester; Guanosine 5'-(trihydrogen diphosphate), P'-alpha-D-glucopyranosyl ester; Guanosine 5'-(trihydrogen diphosphate), P'-I+--D-glucopyranosyl ester; Guanosine 5'-(trihydrogen diphosphoric acid), P'-a-D-glucopyranosyl ester; Guanosine 5'-(trihydrogen diphosphoric acid), P'-alpha-D-glucopyranosyl ester; Guanosine 5'-(trihydrogen diphosphoric acid), P'-I+--D-glucopyranosyl ester; guanosine 5'-[3-(alpha-D-glucopyranosyl) dihydrogen diphosphate]; Guanosine 5'-diphosphate glucose; Guanosine 5'-diphosphate-D-glucose; Guanosine diphosphate D-glucose; guanosine diphosphate glucose; guanosine diphosphate glucose, (D)-isomer; guanosine diphosphate glucose, 14C-labeled; guanosine diphosphoglucose; Guanosine diphosphoric acid glucose; P-alpha-D-glucopyranosyl ester; P-alpha-delta-glucopyranosyl ester



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome()

BioCyc()

PlantCyc()

代谢反应

2 个相关的代谢反应过程信息。

Reactome()

BioCyc()

WikiPathways()

Plant Reactome()

INOH()

PlantCyc(2)

COVID-19 Disease Map()

PathBank()

PharmGKB()

个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Jenny C Mortimer, Xiaolan Yu, Sandra Albrecht, Francesca Sicilia, Mariela Huichalaf, Diego Ampuero, Louise V Michaelson, Alex M Murphy, Toshiro Matsunaga, Samantha Kurz, Elaine Stephens, Timothy C Baldwin, Tadashi Ishii, Johnathan A Napier, Andreas P M Weber, Michael G Handford, Paul Dupree. Abnormal glycosphingolipid mannosylation triggers salicylic acid-mediated responses in Arabidopsis. The Plant cell. 2013 May; 25(5):1881-94. doi: 10.1105/tpc.113.111500. [PMID: 23695979]
  • Hyojin Ko, Ingrid Fricks, Andrei A Ivanov, T Kendall Harden, Kenneth A Jacobson. Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor. Journal of medicinal chemistry. 2007 May; 50(9):2030-9. doi: 10.1021/jm061222w. [PMID: 17407275]
  • H Y Kim, D Thomas, M R Hanley. Stimulation of Ca(2+)-dependent membrane currents in Xenopus oocytes by microinjection of pyrimidine nucleotide-glucose conjugates. Molecular pharmacology. 1996 Feb; 49(2):360-4. doi: . [PMID: 8632770]
  • G Piro, A Zuppa, G Dalessandro, D H Northcote. Glucomannan synthesis in pea epicotyls: the mannose and glucose transferases. Planta. 1993; 190(2):206-20. doi: 10.1007/bf00196613. [PMID: 7685647]
  • R E Campbell, C T Brett, J R Hillman. A xylosyltransferase involved in the synthesis of a protein-associated xyloglucan in suspension-cultured dwarf-French-bean (Phaseolus vulgaris) cells and its interaction with a glucosyltransferase. The Biochemical journal. 1988 Aug; 253(3):795-800. doi: 10.1042/bj2530795. [PMID: 2460084]
  • C M Chadwick, D H Northcote. Glucosylation of phosphorylpolyisoprenol and sterol at the plasma membrane of soya-bean (Glycine max) protoplasts. The Biochemical journal. 1980 Feb; 186(2):411-21. doi: 10.1042/bj1860411. [PMID: 6445731]