(5-Hydroxy-4,6-dimethylpyridin-3-yl)methyl phosphate (BioDeep_00000897196)
代谢物信息卡片
(5-Hydroxy-4,6-dimethylpyridin-3-yl)methyl phosphate
化学式: C8H10NO5P-2 (231.0297)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(C(=NC=C1COP(=O)([O-])[O-])C)O
InChI: InChI=1S/C8H12NO5P/c1-5-7(4-14-15(11,12)13)3-9-6(2)8(5)10/h3,10H,4H2,1-2H3,(H2,11,12,13)/p-2
描述信息
D018977 - Micronutrients > D014815 - Vitamins
同义名列表
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Man Yuan, Feng Wang, Tieqiang Sun, Xiangyu Bian, Yuxian Zhang, Changjiang Guo, Lixia Yu, Zhanxin Yao. Vitamin B6 alleviates chronic sleep deprivation-induced hippocampal ferroptosis through CBS/GSH/GPX4 pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2024 May; 174(?):116547. doi:
10.1016/j.biopha.2024.116547. [PMID: 38599059] - Samah Ali, Marwa Dayo, Sana Alahmadi, Amr Mohamed. Chitosan-Supported ZnO Nanoparticles: Their Green Synthesis, Characterization, and Application for the Removal of Pyridoxine HCl (Vitamin B6) from Aqueous Media.
Molecules (Basel, Switzerland).
2024 Feb; 29(4):. doi:
10.3390/molecules29040828. [PMID: 38398580] - Fanghua Guo, Hua Xiong, Rong Tsao, Fereidoon Shahidi, Xushen Wen, Jiahua Liu, Li Jiang, Yong Sun. Green Pea (Pisum sativum L.) Hull Polyphenol Extract Alleviates NAFLD through VB6/TLR4/NF-κB and PPAR Pathways.
Journal of agricultural and food chemistry.
2023 Nov; 71(43):16067-16078. doi:
10.1021/acs.jafc.3c02337. [PMID: 37861789] - Priscille Steensma, Marion Eisenhut, Maite Colinas, Laise Rosado-Souza, Alisdair R Fernie, Andreas P M Weber, Teresa B Fitzpatrick. PYRIDOX(AM)INE 5'-PHOSPHATE OXIDASE3 of Arabidopsis thaliana maintains carbon/nitrogen balance in distinct environmental conditions.
Plant physiology.
2023 09; 193(2):1433-1455. doi:
10.1093/plphys/kiad411. [PMID: 37453131] - S Palacios, C Mustata, J M Rizo, P A Regidor. Improvement in menopausal symptoms with a nutritional product containing evening primrose oil, hop extract, saffron, tryptophan, vitamins B6, D3, K2, B12, and B9.
European review for medical and pharmacological sciences.
2023 Sep; 27(17):8180-8189. doi:
10.26355/eurrev_202309_33578. [PMID: 37750646] - Shuchen Wang, Xiaoyi Zhang, Zhichao Zhang, Yun Chen, Qing Tian, Dandan Zeng, Miao Xu, Yan Wang, Suomeng Dong, Zhonghua Ma, Yuanchao Wang, Xiaobo Zheng, Wenwu Ye. Fusarium-produced vitamin B6 promotes the evasion of soybean resistance by Phytophthora sojae.
Journal of integrative plant biology.
2023 May; ?(?):. doi:
10.1111/jipb.13505. [PMID: 37171031] - Xiaomeng Cheng, Yuanlong Hu, Zhishen Ruan, Guodong Zang, Xianhai Chen, Zhanjun Qiu. Association between B-vitamins intake and frailty among patients with chronic obstructive pulmonary disease.
Aging clinical and experimental research.
2023 Apr; 35(4):793-801. doi:
10.1007/s40520-023-02353-7. [PMID: 36719551] - Je Won Ko, Sookyoung Jeon, Young Hye Kwon. Dietary vitamin B6 restriction aggravates neurodegeneration in mice fed a high-fat diet.
Life sciences.
2022 Nov; 309(?):121041. doi:
10.1016/j.lfs.2022.121041. [PMID: 36208656] - Hanxia Wang, Qiaoyun Ma, Fuhua Shan, Liping Tian, Jie Gong, Wei Quan, Weibing Yang, Qiling Hou, Fengting Zhang, Shengquan Zhang. Transcriptional regulation mechanism of wheat varieties with different nitrogen use efficiencies in response to nitrogen deficiency stress.
BMC genomics.
2022 Oct; 23(1):727. doi:
10.1186/s12864-022-08948-0. [PMID: 36289540] - Qian Zhang, Xiaoli Zhou, Jingshu Zhang, Qian Li, Zhiyong Qian. Selenium and vitamin B6 cosupplementation improves dyslipidemia and fatty liver syndrome by SIRT1/SREBP-1c pathway in hyperlipidemic Sprague-Dawley rats induced by high-fat diet.
Nutrition research (New York, N.Y.).
2022 10; 106(?):101-118. doi:
10.1016/j.nutres.2022.06.010. [PMID: 36183668] - Serap Andac-Ozturk, Gökçen Garipoğlu, Jale Çatak, Mustafa Yaman. Investigation of the vitamins B1, B2, and B6 vitamers bioaccessibilities of canned, dried legumes after in vitro gastrointestinal digestion system.
Food research international (Ottawa, Ont.).
2022 10; 160(?):111671. doi:
10.1016/j.foodres.2022.111671. [PMID: 36076445] - Joanna L Clasen, Alicia K Heath, Heleen Van Puyvelde, Inge Huybrechts, Jin Young Park, Pietro Ferrari, Ghislaine Scelo, Arve Ulvik, Øivind Midttun, Per Magne Ueland, Kim Overvad, Anne Kirstine Eriksen, Anne Tjønneland, Rudolf Kaaks, Verena Katzke, Matthias B Schulze, Domenico Palli, Claudia Agnoli, Paolo Chiodini, Rosario Tumino, Carlotta Sacerdote, Raul Zamora-Ros, Miguel Rodriguez-Barranco, Carmen Santiuste, Eva Ardanaz, Pilar Amiano, Julie A Schmidt, Elisabete Weiderpass, Marc Gunter, Elio Riboli, Amanda J Cross, Mattias Johansson, David C Muller. Biomarkers of the transsulfuration pathway and risk of renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC) study.
International journal of cancer.
2022 09; 151(5):708-716. doi:
10.1002/ijc.34009. [PMID: 35366005] - Kursat Gundogan, Faruk S Yucesoy, Nurhayat T Ozer, Sahin Temel, Serap Sahin, Gulsah G Sahin, Murat Sungur, Aliye Esmaoglu, Tutkun Talih, Cevat Yazici, Daniel P Griffith, Thomas R Ziegler. Serum micronutrient levels in critically ill patients receiving continuous renal replacement therapy: A prospective, observational study.
JPEN. Journal of parenteral and enteral nutrition.
2022 07; 46(5):1141-1148. doi:
10.1002/jpen.2378. [PMID: 35383966] - Christopher J Cifelli, Sanjiv Agarwal, Victor L Fulgoni Iii. Association between Intake of Total Dairy and Individual Dairy Foods and Markers of Folate, Vitamin B6 and Vitamin B12 Status in the U.S. Population.
Nutrients.
2022 Jun; 14(12):. doi:
10.3390/nu14122441. [PMID: 35745171] - Lei Xu, Yu-Jing Fang, Meng-Meng Che, Alinuer Abulimiti, Chu-Yi Huang, Cai-Xia Zhang. Association of Serum Pyridoxal-5'-Phosphate, Pyridoxal, and PAr with Colorectal Cancer Risk: A Large-Scale Case-Control Study.
Nutrients.
2022 Jun; 14(12):. doi:
10.3390/nu14122389. [PMID: 35745119] - Hyojung Kim, Evelyn B Enrione, Vijaya Narayanan, Tan Li, Adriana Campa. Associations of Vitamin B6 Intake and Plasma Pyridoxal 5'-Phosphate with Plasma Polyunsaturated Fatty Acids in US Older Adults: Findings from NHANES 2003-2004.
Nutrients.
2022 Jun; 14(11):. doi:
10.3390/nu14112336. [PMID: 35684138] - Francesco Landi, Anna Maria Martone, Francesca Ciciarello, Vincenzo Galluzzo, Giulia Savera, Riccardo Calvani, Anna Picca, Emanuele Marzetti, Matteo Tosato, On Behalf Of Gemelli Against Covid-Post-Acute Care Team. Effects of a New Multicomponent Nutritional Supplement on Muscle Mass and Physical Performance in Adult and Old Patients Recovered from COVID-19: A Pilot Observational Case-Control Study.
Nutrients.
2022 May; 14(11):. doi:
10.3390/nu14112316. [PMID: 35684113] - Haifeng Liu, Chongchong Lu, Yang Li, Tao Wu, Baogang Zhang, Baoyou Liu, Wenjie Feng, Qian Xu, Hansong Dong, Shengyang He, Zhaohui Chu, Xinhua Ding. The bacterial effector AvrRxo1 inhibits vitamin B6 biosynthesis to promote infection in rice.
Plant communications.
2022 05; 3(3):100324. doi:
10.1016/j.xplc.2022.100324. [PMID: 35576156] - Ying Liu, Rodolfo A Maniero, Ricardo F H Giehl, Michael Melzer, Priscille Steensma, Gabriel Krouk, Teresa B Fitzpatrick, Nicolaus von Wirén. PDX1.1-dependent biosynthesis of vitamin B6 protects roots from ammonium-induced oxidative stress.
Molecular plant.
2022 05; 15(5):820-839. doi:
10.1016/j.molp.2022.01.012. [PMID: 35063660] - Sarah L Stewart, Simone Thomas, Erol Höke, David Simpson, J Robinson Singleton, Ahmet Höke. Vitamin B6 levels do not correlate with severity of neuropathy in chronic idiopathic axonal polyneuropathy.
Journal of the peripheral nervous system : JPNS.
2022 03; 27(1):31-37. doi:
10.1111/jns.12480. [PMID: 34931740] - Kyeoung-Hwa Kim, Kyung-Ah Lee. Metabolic Rewiring by Human Placenta-Derived Mesenchymal Stem Cell Therapy Promotes Rejuvenation in Aged Female Rats.
International journal of molecular sciences.
2022 Jan; 23(1):. doi:
10.3390/ijms23010566. [PMID: 35008991] - Michael P Whyte, Fan Zhang, Deborah Wenkert, Karen E Mack, Vinieth N Bijanki, Karen L Ericson, Stephen P Coburn. Hypophosphatasia: Vitamin B6 status of affected children and adults.
Bone.
2022 01; 154(?):116204. doi:
10.1016/j.bone.2021.116204. [PMID: 34547524] - Jin-Peng Zhu, Hao Gong, Faiza Labreche, Xiao-Hong Kou, Cai-E Wu, Gong-Jian Fan, Ting-Ting Li, Jia-Hong Wang, Dong-Bei Shen. Age-dependent alteration in metabolism of vitamin B6 , neurotransmitters, and amino acids after 4'-O-methylpyridoxine administration in rats.
Journal of food science.
2022 Jan; 87(1):466-480. doi:
10.1111/1750-3841.15997. [PMID: 34914095] - Gloria Olaso-Gonzalez, Marco Inzitari, Giuseppe Bellelli, Alessandro Morandi, Núria Barcons, José Viña. Impact of supplementation with vitamins B6 , B12 , and/or folic acid on the reduction of homocysteine levels in patients with mild cognitive impairment: A systematic review.
IUBMB life.
2022 01; 74(1):74-84. doi:
10.1002/iub.2507. [PMID: 34058062] - Yanhua Liu, Kunli Yang, Ling Wang, Jinfang Yang, Yang Wang, Hu Luo, Peng Li, Yaling Yin. Vitamin B6 prevents Isocarbophos-induced posterior cerebral artery injury in offspring rats through up-regulating S1P receptor expression.
Acta biochimica et biophysica Sinica.
2021 Dec; 53(12):1691-1701. doi:
10.1093/abbs/gmab150. [PMID: 34718372] - Xian Wu, Per M Ueland, Jatin Roper, Gar Yee Koh, Xu Liang, Jimmy W Crott, Ömer H Yilmaz, Roderick T Bronson, Joel B Mason. Combined Supplementation with Vitamin B-6 and Curcumin is Superior to Either Agent Alone in Suppressing Obesity-Promoted Colorectal Tumorigenesis in Mice.
The Journal of nutrition.
2021 12; 151(12):3678-3688. doi:
10.1093/jn/nxab320. [PMID: 34590119] - Irina V Novikova, Mowei Zhou, Chen Du, Marcelina Parra, Doo Nam Kim, Zachary L VanAernum, Jared B Shaw, Hanjo Hellmann, Vicki H Wysocki, James E Evans. Tunable Heteroassembly of a Plant Pseudoenzyme-Enzyme Complex.
ACS chemical biology.
2021 11; 16(11):2315-2325. doi:
10.1021/acschembio.1c00475. [PMID: 34520180] - Kamilla Stach, Wojciech Stach, Katarzyna Augoff. Vitamin B6 in Health and Disease.
Nutrients.
2021 Sep; 13(9):. doi:
10.3390/nu13093229. [PMID: 34579110] - Martina Tynes, Matthias Hepprich, Katharina Timper. Regular intake of energy drinks and multivitamin supplements is associated with elevated plasma vitamin B6 levels in post-bariatric patients.
Scientific reports.
2021 09; 11(1):17830. doi:
10.1038/s41598-021-97205-7. [PMID: 34497284] - Chuxi Pan, Alexandra Zimmer, Megha Shah, Minh Sang Huynh, Christine Chieh-Lin Lai, Brandon Sit, Yogesh Hooda, David M Curran, Trevor F Moraes. Actinobacillus utilizes a binding protein-dependent ABC transporter to acquire the active form of vitamin B6.
The Journal of biological chemistry.
2021 09; 297(3):101046. doi:
10.1016/j.jbc.2021.101046. [PMID: 34358566] - Michael P Whyte, Jennifer D May, William H McAlister, Katherine Burgener, Samuel R Cortez, Raymond Kreienkamp, Olivia Castro, Rachel Verzola, Ana Solis Zavala, Christopher C McPherson, Gary S Gottesman, Karen L Ericson, Stephen P Coburn, Ana Maria Arbelaez. Vitamin B6 deficiency with normal plasma levels of pyridoxal 5'-phosphate in perinatal hypophosphatasia.
Bone.
2021 09; 150(?):116007. doi:
10.1016/j.bone.2021.116007. [PMID: 34000433] - Donghui Yang, Yan Liu, Yafeng Wang, Yudiyang Ma, Jianjun Bai, Chuanhua Yu. Association of Serum Vitamin B6 with All-Cause and Cause-Specific Mortality in a Prospective Study.
Nutrients.
2021 Aug; 13(9):. doi:
10.3390/nu13092977. [PMID: 34578855] - Ching-Ti Liu, David Karasik, Hanfei Xu, Yanhua Zhou, Kerry Broe, L Adrienne Cupples, Lisette Cpgm de Groot, Annelies Ham, Marian T Hannan, Yi-Hsiang Hsu, Paul Jacques, Robert R McLean, Ligi Paul, Jacob Selhub, Katerina Trajanoska, Nathalie van der Velde, Natasja van Schoor, Douglas P Kiel. Genetic variants modify the associations of concentrations of methylmalonic acid, vitamin B-12, vitamin B-6, and folate with bone mineral density.
The American journal of clinical nutrition.
2021 08; 114(2):578-587. doi:
10.1093/ajcn/nqab093. [PMID: 33964857] - Sundus M Sallabi, Aishah Alhmoudi, Manal Alshekaili, Iltaf Shah. Determination of Vitamin B3 Vitamer (Nicotinamide) and Vitamin B6 Vitamers in Human Hair Using LC-MS/MS.
Molecules (Basel, Switzerland).
2021 Jul; 26(15):. doi:
10.3390/molecules26154487. [PMID: 34361640] - Mathias D G Van den Eynde, Jean L J M Scheijen, Coen D A Stehouwer, Toshio Miyata, Casper G Schalkwijk. Quantification of the B6 vitamers in human plasma and urine in a study with pyridoxamine as an oral supplement; pyridoxamine as an alternative for pyridoxine.
Clinical nutrition (Edinburgh, Scotland).
2021 07; 40(7):4624-4632. doi:
10.1016/j.clnu.2021.05.028. [PMID: 34229268] - Shuai Yuan, Paul Carter, Mathew Vithayathil, Siddhartha Kar, Amy M Mason, Stephen Burgess, Susanna C Larsson. Genetically predicted circulating B vitamins in relation to digestive system cancers.
British journal of cancer.
2021 06; 124(12):1997-2003. doi:
10.1038/s41416-021-01383-0. [PMID: 33837300] - Paula Schorgg, Till Bärnighausen, Sabine Rohrmann, Aedin Cassidy, Nena Karavasiloglou, Tilman Kühn. Vitamin B6 Status among Vegetarians: Findings from a Population-Based Survey.
Nutrients.
2021 May; 13(5):. doi:
10.3390/nu13051627. [PMID: 34066199] - Kazuya Toriumi, Mitsuhiro Miyashita, Kazuhiro Suzuki, Nao Yamasaki, Misako Yasumura, Yasue Horiuchi, Akane Yoshikawa, Mai Asakura, Noriyoshi Usui, Masanari Itokawa, Makoto Arai. Vitamin B6 deficiency hyperactivates the noradrenergic system, leading to social deficits and cognitive impairment.
Translational psychiatry.
2021 05; 11(1):262. doi:
10.1038/s41398-021-01381-z. [PMID: 33941768] - Leslie Y Chiang, Brett Baumann, Kamila Romanowski, Divjot Kumar, Jonathon R Campbell, Ognjenka Djurdjev, Muhammad Morshed, Inna Sekirov, Victoria J Cook, Adeera Levin, James C Johnston. Latent Tuberculosis Therapy Outcomes in Dialysis Patients: A Retrospective Cohort.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2021 05; 77(5):696-703. doi:
10.1053/j.ajkd.2020.06.017. [PMID: 32818551] - Benjamin Warren, Jerome Sarris, Roger T Mulder, Julia J Rucklidge. Pyroluria: Fact or Fiction?.
Journal of alternative and complementary medicine (New York, N.Y.).
2021 May; 27(5):407-415. doi:
10.1089/acm.2020.0151. [PMID: 33902305] - Jamaji C Nwanaji-Enwerem, Elena Colicino, Xu Gao, Cuicui Wang, Pantel Vokonas, Edward W Boyer, Andrea A Baccarelli, Joel Schwartz. Associations of Plasma Folate and Vitamin B6 With Blood DNA Methylation Age: An Analysis of One-Carbon Metabolites in the VA Normative Aging Study.
The journals of gerontology. Series A, Biological sciences and medical sciences.
2021 04; 76(5):760-769. doi:
10.1093/gerona/glaa257. [PMID: 33027507] - Mark M Kushnir, Boya Song, Evelyn Yang, Elizabeth L Frank. Development and Clinical Evaluation of a High-Throughput LC-MS/MS Assay for Vitamin B6 in Human Plasma and Serum.
The journal of applied laboratory medicine.
2021 04; 6(3):702-714. doi:
10.1093/jalm/jfaa166. [PMID: 33279978] - Ali O Alqarni, Saad A Alkahtani, Ashraf M Mahmoud, Mohamed M El-Wekil. Design of 'Turn On' fluorometric nanoprobe based on nitrogen doped graphene quantum dots modified with β-cyclodextrin and vitamin B6 cofactor for selective sensing of dopamine in human serum.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2021 Mar; 248(?):119180. doi:
10.1016/j.saa.2020.119180. [PMID: 33234475] - Stephanie Andraos, Beatrix Jones, Clare Wall, Eric Thorstensen, Martin Kussmann, David Cameron-Smith, Katherine Lange, Susan Clifford, Richard Saffery, David Burgner, Melissa Wake, Justin O'Sullivan. Plasma B Vitamers: Population Epidemiology and Parent-Child Concordance in Children and Adults.
Nutrients.
2021 Mar; 13(3):. doi:
10.3390/nu13030821. [PMID: 33801409] - Aitor Benedicto, Iera Hernandez-Unzueta, Eduardo Sanz, Joana Márquez. Ocoxin Increases the Antitumor Effect of BRAF Inhibition and Reduces Cancer Associated Fibroblast-Mediated Chemoresistance and Protumoral Activity in Metastatic Melanoma.
Nutrients.
2021 Feb; 13(2):. doi:
10.3390/nu13020686. [PMID: 33669949] - Wenxue Guan, Ge Wang, Feng Hu, Xiaoyan Peng. Partial regression of foveoschisis following vitamin B6 supplementary therapy for gyrate atrophy in a Chinese girl.
BMC ophthalmology.
2021 Feb; 21(1):93. doi:
10.1186/s12886-021-01862-1. [PMID: 33602140] - Filippo Rossi, Giorgia Spigno, Gloria Luzzani, Maria Elisabetta Bozzoni, Gianluca Donadini, Jessica Rolla, Terenzio Bertuzzi. Effects of the intake of craft or industrial beer on serum homocysteine.
International journal of food sciences and nutrition.
2021 Feb; 72(1):93-98. doi:
10.1080/09637486.2020.1760219. [PMID: 32366139] - Qinati Feyissa, Fei Xu, Zina Ibrahim, Ying Li, Kevin L Xu, Zihan Guo, Justen Ahmad, Jaroslav G Vostal. Synergistic bactericidal effects of pairs of photosensitizer molecules activated by ultraviolet A light against bacteria in plasma.
Transfusion.
2021 02; 61(2):594-602. doi:
10.1111/trf.16180. [PMID: 33219568] - Yaling Lu, Xiangping Wu, Lei Yuan, Yingdi Li, Penghui Wang, Jianna Yu, Pingfang Tian, Wenjie Liu. A rapid liquid chromatography-electrospray ionization-ion mobility spectrometry method for monitoring nine representative metabolites in the seedlings of cucumber and wheat.
Journal of separation science.
2021 Feb; 44(3):709-716. doi:
10.1002/jssc.202000811. [PMID: 33245598] - Kristie Searcy, Sarah Rainwater, Majed Jeroudi, Radhakrishna Baliga. Erythropoietin-stimulating agent-resistant vitamin B6 deficiency anemia in a pediatric patient on hemodialysis.
Pediatric nephrology (Berlin, Germany).
2021 02; 36(2):473-476. doi:
10.1007/s00467-020-04810-1. [PMID: 33156411] - Hyojung Kim, Evelyn B Enrione, Vijaya Narayanan, Tan Li, Adriana Campa. Gender Differences in the Associations of Plasma Pyridoxal 5'-Phosphate with Plasma Polyunsaturated Fatty Acids among US Young and Middle-Aged Adults: NHANES 2003-2004.
Nutrients.
2021 Jan; 13(2):. doi:
10.3390/nu13020477. [PMID: 33572554] - Jessica Hoffmann, Stefan Busse, Franz von Hoff, Katrin Borucki, Thomas Frodl, Mandy Busse. Association Between Homocysteine and Vitamin Levels in Demented Patients.
Journal of Alzheimer's disease : JAD.
2021; 81(4):1781-1792. doi:
10.3233/jad-201481. [PMID: 33998538] - Qian Zhang, Da-Long Zhang, Xiao-Li Zhou, Qian Li, Ning He, Jing Zhang, Qing Gu, Zhi-Yong Qian. Antihyperlipidemic and Hepatoprotective Properties of Vitamin B6 Supplementation in Rats with High-Fat Diet-Induced Hyperlipidemia.
Endocrine, metabolic & immune disorders drug targets.
2021; 21(12):2260-2272. doi:
10.2174/1871530321666210809152555. [PMID: 34370653] - Irina Alexandrovna Lapik, Rajesh Ranjit, Alexey Vladimirovich Galchenko. Impact of KCNJ11 rs5219, UCP2 rs659366, and MTHFR rs1801133 Polymorphisms on Type 2 Diabetes: A Cross-Sectional Study.
The review of diabetic studies : RDS.
2021; 17(1):21-29. doi:
10.1900/rds.2021.17.21. [PMID: 34289004] - Hui Han, Feng Wang, Juanjuan Chen, Xingxing Li, Gaoqing Fu, Jiawei Zhou, Dongsheng Zhou, Wei Wu, Haimin Chen. Changes in Biothiol Levels Are Closely Associated with Alzheimer's Disease.
Journal of Alzheimer's disease : JAD.
2021; 82(2):527-540. doi:
10.3233/jad-210021. [PMID: 34024827] - Aitor Benedicto, Eduardo Sanz, Joana Márquez. Ocoxin as a complement to first line treatments in cancer.
International journal of medical sciences.
2021; 18(3):835-845. doi:
10.7150/ijms.50122. [PMID: 33437220] - Joanna L Clasen, Alicia K Heath, Ghislaine Scelo, David C Muller. Components of one-carbon metabolism and renal cell carcinoma: a systematic review and meta-analysis.
European journal of nutrition.
2020 Dec; 59(8):3801-3813. doi:
10.1007/s00394-020-02211-6. [PMID: 32162043] - Manoela T da Silva, Maria F Mujica-Coopman, Amanda C C Figueiredo, Daniela Hampel, Luna S Vieira, Dayana R Farias, Setareh Shahab-Ferdows, Lindsay H Allen, Alex Brito, Yvonne Lamers, Gilberto Kac, Juliana S Vaz. Maternal plasma folate concentration is positively associated with serum total cholesterol and low-density lipoprotein across the three trimesters of pregnancy.
Scientific reports.
2020 11; 10(1):20141. doi:
10.1038/s41598-020-77231-7. [PMID: 33214613] - Yogendra Singh, Gaurav Gupta, Imran Kazmi, Fahad A Al-Abbasi, Poonam Negi, Dinesh Kumar Chellappan, Kamal Dua. SARS CoV-2 aggravates cellular metabolism mediated complications in COVID-19 infection.
Dermatologic therapy.
2020 11; 33(6):e13871. doi:
10.1111/dth.13871. [PMID: 32558055] - Alexandra Jungert, Helene McNulty, Leane Hoey, Mary Ward, J J Strain, Catherine F Hughes, Liadhan McAnena, Monika Neuhäuser-Berthold, Kristina Pentieva. Riboflavin Is an Important Determinant of Vitamin B-6 Status in Healthy Adults.
The Journal of nutrition.
2020 10; 150(10):2699-2706. doi:
10.1093/jn/nxaa225. [PMID: 32805038] - Jie Zhu, Cheng Chen, Liping Lu, Kefeng Yang, Jared Reis, Ka He. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to Diabetes Incidence Among American Young Adults: A 30-Year Follow-up Study.
Diabetes care.
2020 10; 43(10):2426-2434. doi:
10.2337/dc20-0828. [PMID: 32737139] - Thomas Bachmann, Andrea Maurer, Michael Rychlik. Development of a LC-MS/MS method using stable isotope dilution for the quantification of individual B6 vitamers in fruits, vegetables, and cereals.
Analytical and bioanalytical chemistry.
2020 Oct; 412(26):7237-7252. doi:
10.1007/s00216-020-02857-5. [PMID: 32797304] - Isidor Minović, Lyanne M Kieneker, Ron T Gansevoort, Manfred Eggersdorfer, Daan J Touw, Albert-Jan Voerman, Margery A Connelly, Rudolf A de Boer, Eelko Hak, Jens Bos, Robin P F Dullaart, Ido P Kema, Stephan J L Bakker. Vitamin B6, Inflammation, and Cardiovascular Outcome in a Population-Based Cohort: The Prevention of Renal and Vascular End-Stage Disease (PREVEND) Study.
Nutrients.
2020 Sep; 12(9):. doi:
10.3390/nu12092711. [PMID: 32899820] - Shuraku Son, Makoto Arai, Jun Miyata, Kazuya Toriumi, Hiroto Mizuta, Takuya Hayashi, Toshihiko Aso, Masanari Itokawa, Toshiya Murai. Enhanced carbonyl stress and disrupted white matter integrity in schizophrenia.
Schizophrenia research.
2020 09; 223(?):242-248. doi:
10.1016/j.schres.2020.08.007. [PMID: 32843203] - Yukiko Tomioka, Makoto Kinoshita, Hidehiro Umehara, Tomohiko Nakayama, Shin-Ya Watanabe, Masahito Nakataki, Shusuke Numata, Tetsuro Ohmori. Association between serum folate levels and schizophrenia based on sex.
Psychiatry and clinical neurosciences.
2020 Sep; 74(9):466-471. doi:
10.1111/pcn.13074. [PMID: 32445495] - Ana Rojo-Sebastián, Cristina González-Robles, Justo García de Yébenes. Vitamin B6 Deficiency in Patients With Parkinson Disease Treated With Levodopa/Carbidopa.
Clinical neuropharmacology.
2020 Sep; 43(5):151-157. doi:
10.1097/wnf.0000000000000408. [PMID: 32947426] - Dinesh Talwar, Anthony Catchpole, John M Wadsworth, Barry J Toole, Donald C McMillan. The relationship between plasma albumin, alkaline phosphatase and pyridoxal phosphate concentrations in plasma and red cells: Implications for assessing vitamin B6 status.
Clinical nutrition (Edinburgh, Scotland).
2020 09; 39(9):2824-2831. doi:
10.1016/j.clnu.2019.12.012. [PMID: 31883613] - Mirco Dindo, Giorgia Mandrile, Carolina Conter, Rosa Montone, Daniela Giachino, Alessandra Pelle, Claudio Costantini, Barbara Cellini. The ILE56 mutation on different genetic backgrounds of alanine:glyoxylate aminotransferase: Clinical features and biochemical characterization.
Molecular genetics and metabolism.
2020 Sep; 131(1-2):171-180. doi:
10.1016/j.ymgme.2020.07.012. [PMID: 32792227] - Yinjie Zhu, Isidor Minović, Louise H Dekker, Manfred L Eggersdorfer, Sander K R van Zon, Sijmen A Reijneveld, Jenny E Kootstra-Ros, Ido P Kema, Stephan J L Bakker, Gerjan J Navis, Ineke J Riphagen. Vitamin Status and Diet in Elderly with Low and High Socioeconomic Status: The Lifelines-MINUTHE Study.
Nutrients.
2020 Aug; 12(9):. doi:
10.3390/nu12092659. [PMID: 32878227] - Atanasio Pandiella-Alonso, Elena Díaz-Rodríguez, Eduardo Sanz. Antitumoral Properties of the Nutritional Supplement Ocoxin Oral Solution: A Comprehensive Review.
Nutrients.
2020 Aug; 12(9):. doi:
10.3390/nu12092661. [PMID: 32878230] - Min Zhu, Xiujing Liu, Changhui Zhou, Juan Li. Effect of sodium cantharidinate/vitamin B6 injection on survival, liver function, immune function, and quality of life in patients with hepatocellular carcinoma: Protocol for a meta-analysis.
Medicine.
2020 Aug; 99(34):e21952. doi:
10.1097/md.0000000000021952. [PMID: 32846865] - Lionel Noah, Gisele Pickering, Andre Mazur, Claude Dubray, Simon Hitier, Christian Dualé, Etienne Pouteau. Impact of magnesium supplementation, in combination with vitamin B6, on stress and magnesium status: secondary data from a randomized controlled trial.
Magnesium research.
2020 Aug; 33(3):45-57. doi:
10.1684/mrh.2020.0468. [PMID: 33210604] - Natalie Keller, Natalia Mendoza-Ferreira, Reza Maroofian, Viorica Chelban, Youssef Khalil, Philippa B Mills, Reza Boostani, Paria Najarzadeh Torbati, Ehsan Ghayoor Karimiani, Holger Thiele, Henry Houlden, Brunhilde Wirth, Mert Karakaya. Hereditary polyneuropathy with optic atrophy due to PDXK variant leading to impaired Vitamin B6 metabolism.
Neuromuscular disorders : NMD.
2020 07; 30(7):583-589. doi:
10.1016/j.nmd.2020.04.004. [PMID: 32522499] - Guoqing Yan, Ran Chen, Nanchi Xiong, Jiayu Song, Xin Wang, Rupei Tang. pH-sensitive small molecule nanodrug self-assembled from amphiphilic vitamin B6-E analogue conjugate for targeted synergistic cancer therapy.
Colloids and surfaces. B, Biointerfaces.
2020 Jul; 191(?):111000. doi:
10.1016/j.colsurfb.2020.111000. [PMID: 32247946] - Malkanthi Evans, Abdul M Sulley, David C Crowley, Jamie Langston, Najla Guthrie. Pain Bloc-R Alleviates Unresolved, Non-Pathological Aches and Discomfort in Healthy Adults-A Randomized, Double-Blind, Placebo-Controlled, Crossover Study.
Nutrients.
2020 Jun; 12(6):. doi:
10.3390/nu12061831. [PMID: 32575480] - Shahla Teimouri, Stefan Kasapis. Morphology of genipin-crosslinked BSA networks yields a measurable effect on the controlled release of vitamin B6.
Food chemistry.
2020 Jun; 314(?):126204. doi:
10.1016/j.foodchem.2020.126204. [PMID: 31978719] - Saleem Ali Banihani, Shefa' Muneer Aljabali. Seminal plasma vitamin B6 levels in men with asthenozoospermia and men with normal sperm motility, a measurement using liquid chromatography with tandem mass spectrometry.
Andrologia.
2020 May; 52(4):e13556. doi:
10.1111/and.13556. [PMID: 32129519] - Gauri Desai, Marie Vahter, Elena I Queirolo, Fabiana Peregalli, Nelly Mañay, Amy E Millen, Jihnhee Yu, Richard W Browne, Katarzyna Kordas. Vitamin B-6 Intake Is Modestly Associated with Arsenic Methylation in Uruguayan Children with Low-Level Arsenic Exposure.
The Journal of nutrition.
2020 05; 150(5):1223-1229. doi:
10.1093/jn/nxz331. [PMID: 31913474] - Keewan Kim, James L Mills, Kara A Michels, Ellen N Chaljub, Jean Wactawski-Wende, Torie C Plowden, Sunni L Mumford. Dietary Intakes of Vitamin B-2 (Riboflavin), Vitamin B-6, and Vitamin B-12 and Ovarian Cycle Function among Premenopausal Women.
Journal of the Academy of Nutrition and Dietetics.
2020 05; 120(5):885-892. doi:
10.1016/j.jand.2019.10.013. [PMID: 31879178] - Maria Cappuccilli, Camilla Bergamini, Floriana A Giacomelli, Giuseppe Cianciolo, Gabriele Donati, Diletta Conte, Teresa Natali, Gaetano La Manna, Irene Capelli. Vitamin B Supplementation and Nutritional Intake of Methyl Donors in Patients with Chronic Kidney Disease: A Critical Review of the Impact on Epigenetic Machinery.
Nutrients.
2020 Apr; 12(5):. doi:
10.3390/nu12051234. [PMID: 32349312] - Małgorzata Szczuko, Viktoria Hawryłkowicz, Justyna Kikut, Arleta Drozd. The implications of vitamin content in the plasma in reference to the parameters of carbohydrate metabolism and hormone and lipid profiles in PCOS.
The Journal of steroid biochemistry and molecular biology.
2020 04; 198(?):105570. doi:
10.1016/j.jsbmb.2019.105570. [PMID: 31883924] - Natsuki Tsujita, Yasunori Akamatsu, Márcio Makoto Nishida, Tatsuya Hayashi, Toshio Moritani. Physical Activity, Nutritional Status, and Autonomic Nervous System Activity in Healthy Young Adults with Higher Levels of Depressive Symptoms and Matched Controls without Depressive Symptoms: A Cross-Sectional Study.
Nutrients.
2020 Mar; 12(3):. doi:
10.3390/nu12030690. [PMID: 32143525] - Mei-Rong Shan, Sheng-Nan Zhou, Chang-Ning Fu, Jia-Wen Song, Xue-Qing Wang, Wen-Wu Bai, Peng Li, Ping Song, Mo-Li Zhu, Zhi-Min Ma, Zhan Liu, Jian Xu, Bo Dong, Chao Liu, Tao Guo, Cheng Zhang, Shuang-Xi Wang. Vitamin B6 inhibits macrophage activation to prevent lipopolysaccharide-induced acute pneumonia in mice.
Journal of cellular and molecular medicine.
2020 03; 24(5):3139-3148. doi:
10.1111/jcmm.14983. [PMID: 31970902] - Pariya Behrouzi, Pol Grootswagers, Paul L C Keizer, Ellen T H C Smeets, Edith J M Feskens, Lisette C P G M de Groot, Fred A van Eeuwijk. Dietary Intakes of Vegetable Protein, Folate, and Vitamins B-6 and B-12 Are Partially Correlated with Physical Functioning of Dutch Older Adults Using Copula Graphical Models.
The Journal of nutrition.
2020 03; 150(3):634-643. doi:
10.1093/jn/nxz269. [PMID: 31858107] - Alexandra Jungert, Monika Neuhäuser-Berthold. Determinants of Vitamin B6 Status in Community-Dwelling Older Adults: A Longitudinal Study Over a Period of 18 Years.
The journals of gerontology. Series A, Biological sciences and medical sciences.
2020 01; 75(2):374-379. doi:
10.1093/gerona/glz010. [PMID: 30657862] - Alexandra Jungert, Jakob Linseisen, Karl-Heinz Wagner, Margrit Richter. Revised D-A-CH Reference Values for the Intake of Vitamin B6.
Annals of nutrition & metabolism.
2020; 76(4):213-222. doi:
10.1159/000508618. [PMID: 32690847] - Arve Ulvik, Øivind Midttun, Adrian McCann, Klaus Meyer, Grethe Tell, Ottar Nygård, Per M Ueland. Tryptophan catabolites as metabolic markers of vitamin B-6 status evaluated in cohorts of healthy adults and cardiovascular patients.
The American journal of clinical nutrition.
2020 01; 111(1):178-186. doi:
10.1093/ajcn/nqz228. [PMID: 31557280] - Oleksandr I Smiyan, Yuliia A Man'ko, Andrii M Loboda, Sergii V Popov, Igor Yu Vysots'kyy, Victoria O Petrashenko, Igor M Martsovenko, Kateryna O Smiian, Valentina A Plakhuta, Volodymyr M Serhiyenko, Olena L Ovsyanko, Tatiana O Aleksakhina, Al-Rawashdeh Bara. Influence of magnesium on the state of the cardiovascular system in children with chronic tonsilitis.
Wiadomosci lekarskie (Warsaw, Poland : 1960).
2020; 73(5):904-908. doi:
10.36740/wlek202005112. [PMID: 32386366] - Nan Nan, Jie Wang, Yuejie Shi, Yangwen Qian, Long Jiang, Shuangzhan Huang, Yutong Liu, Ying Wu, Bao Liu, Zheng-Yi Xu. Rice plastidial NAD-dependent malate dehydrogenase 1 negatively regulates salt stress response by reducing the vitamin B6 content.
Plant biotechnology journal.
2020 01; 18(1):172-184. doi:
10.1111/pbi.13184. [PMID: 31161713] - Chenbo Zhang, Jianfeng Luo, Changzheng Yuan, Ding Ding. Vitamin B12, B6, or Folate and Cognitive Function in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis.
Journal of Alzheimer's disease : JAD.
2020; 77(2):781-794. doi:
10.3233/jad-200534. [PMID: 32773392] - L A Marchenkova, A D Fesyun, M Yu Gerasimenko, E V Makarova. [The effect of administration of dietary supplement with calcium and vitamins D3 and B6 on calcium homeostasis and falls incidence in patients with high fracture risk undergoing medical rehabilitation].
Voprosy pitaniia.
2020 ; 89(5):89-100. doi:
10.24411/0042-8833-2020-10069. [PMID: 33211921] - Yachana Upadhyay, Shilpa Bothra, Rajender Kumar, Ashok Kumar Sk, Suban K Sahoo. Mimicking biological process to detect alkaline phosphatase activity using the vitamin B6 cofactor conjugated bovine serum albumin capped CdS quantum dots.
Colloids and surfaces. B, Biointerfaces.
2020 Jan; 185(?):110624. doi:
10.1016/j.colsurfb.2019.110624. [PMID: 31711735] - Fahimeh Khorasani, Hossein Aryan, Abousaleh Sobhi, Reihaneh Aryan, Arefeh Abavi-Sani, Masumeh Ghazanfarpour, Masumeh Saeidi, Fatemeh Rajab Dizavandi. A systematic review of the efficacy of alternative medicine in the treatment of nausea and vomiting of pregnancy.
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology.
2020 Jan; 40(1):10-19. doi:
10.1080/01443615.2019.1587392. [PMID: 31215276] - Akram A Da'dara, Manal Elzoheiry, Samar N El-Beshbishi, Patrick J Skelly. Vitamin B6 Acquisition and Metabolism in Schistosoma mansoni.
Frontiers in immunology.
2020; 11(?):622162. doi:
10.3389/fimmu.2020.622162. [PMID: 33613557] - Fábio V Ued, Mariana G Mathias, Roseli B D Toffano, Tamiris T Barros, Maria Olímpia R V Almada, Roberta G Salomão, Carolina A Coelho-Landell, Elaine Hillesheim, Joyce M Camarneiro, José Simon Camelo-Junior, Davi C Aragon, Sofia Moco, Martin Kussmann, Jim Kaput, Jacqueline P Monteiro. Vitamin B2 and Folate Concentrations are Associated with ARA, EPA and DHA Fatty Acids in Red Blood Cells of Brazilian Children and Adolescents.
Nutrients.
2019 Dec; 11(12):. doi:
10.3390/nu11122918. [PMID: 31810311] - Alina Vrieling, H Bas Bueno-De-Mesquita, Martine M Ros, Ellen Kampman, Katja K Aben, Frederike L Büchner, Eugène H Jansen, Nina Roswall, Anne Tjønneland, Marie-Christine Boutron-Ruault, Claire Cadeau, Jenny Chang-Claude, Rudolf Kaaks, Steffen Weikert, Heiner Boeing, Antonia Trichopoulou, Pagona Lagiou, Dimitrios Trichopoulos, Sabina Sieri, Domenico Palli, Salvatore Panico, Petra H Peeters, Elisabete Weiderpass, Guri Skeie, Paula Jakszyn, María-Dolores Chirlaque, Eva Ardanaz, María-José Sánchez, Roy Ehrnström, Johan Malm, Börje Ljungberg, Kay-Tee Khaw, Nick J Wareham, Paul Brennan, Mattias Johansson, Elio Riboli, Lambertus A Kiemeney. One-carbon metabolism biomarkers and risk of urothelial cell carcinoma in the European prospective investigation into cancer and nutrition.
International journal of cancer.
2019 11; 145(9):2349-2359. doi:
10.1002/ijc.32165. [PMID: 30694528] - Yu An, Lingli Feng, Xiaona Zhang, Ying Wang, Yushan Wang, Lingwei Tao, Zhongsheng Qin, Rong Xiao. Dietary intakes and biomarker patterns of folate, vitamin B6, and vitamin B12 can be associated with cognitive impairment by hypermethylation of redox-related genes NUDT15 and TXNRD1.
Clinical epigenetics.
2019 10; 11(1):139. doi:
10.1186/s13148-019-0741-y. [PMID: 31601260] - Kirsty M Porter, Mary Ward, Catherine F Hughes, Maurice O'Kane, Leane Hoey, Adrian McCann, Anne M Molloy, Conal Cunningham, Miriam C Casey, Fergal Tracey, Sean Strain, Kevin McCarroll, Eamon Laird, Alison M Gallagher, Helene McNulty. Hyperglycemia and Metformin Use Are Associated With B Vitamin Deficiency and Cognitive Dysfunction in Older Adults.
The Journal of clinical endocrinology and metabolism.
2019 10; 104(10):4837-4847. doi:
10.1210/jc.2018-01791. [PMID: 30920623] - Nathalie Mangel, Jared B Fudge, Kuan-Te Li, Ting-Ying Wu, Takayuki Tohge, Alisdair R Fernie, Boris Szurek, Teresa B Fitzpatrick, Wilhelm Gruissem, Hervé Vanderschuren. Enhancement of vitamin B6 levels in rice expressing Arabidopsis vitamin B6 biosynthesis de novo genes.
The Plant journal : for cell and molecular biology.
2019 09; 99(6):1047-1065. doi:
10.1111/tpj.14379. [PMID: 31063672]
