Lovenox (BioDeep_00000897165)

   


代谢物信息卡片


Lovenox

化学式: C26H42N2O37S5 (1134.0069962000002)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)OC4C(C(C(C(O4)C(=O)O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O
InChI: InChI=1S/C26H42N2O37S5/c1-4(30)27-7-9(31)13(6(56-23(7)39)3-55-67(43,44)45)58-26-19(65-70(52,53)54)12(34)16(20(62-26)22(37)38)60-24-8(28-66(40,41)42)15(63-68(46,47)48)14(5(2-29)57-24)59-25-18(64-69(49,50)51)11(33)10(32)17(61-25)21(35)36/h5-20,23-26,28-29,31-34,39H,2-3H2,1H3,(H,27,30)(H,35,36)(H,37,38)(H,40,41,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)

描述信息

B - Blood and blood forming organs > B01 - Antithrombotic agents > B01A - Antithrombotic agents > B01AB - Heparin group
C78275 - Agent Affecting Blood or Body Fluid > C263 - Anticoagulant Agent > C2578 - Low Molecular Weight Heparin
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同义名列表

1 个代谢物同义名

Lovenox



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在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Sophie Maiocchi, Jacqueline Ku, Tom Hawtrey, Irene De Silvestro, Ernst Malle, Martin Rees, Shane R Thomas, Jonathan C Morris. Polyamine-Conjugated Nitroxides Are Efficacious Inhibitors of Oxidative Reactions Catalyzed by Endothelial-Localized Myeloperoxidase. Chemical research in toxicology. 2021 06; 34(6):1681-1692. doi: 10.1021/acs.chemrestox.1c00094. [PMID: 34085520]
  • Ning Tang, Huan Bai, Xing Chen, Jiale Gong, Dengju Li, Ziyong Sun. Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy. Journal of thrombosis and haemostasis : JTH. 2020 05; 18(5):1094-1099. doi: 10.1111/jth.14817. [PMID: 32220112]
  • Koichi Arakawa, Yugo Ikeyama, Tomoyuki Sato, Masahiro Segawa, Shuichi Sekine, Kousei Ito. Functional modulation of liver mitochondria in lipopolysaccharide/drug co-treated rat liver injury model. The Journal of toxicological sciences. 2019; 44(12):833-843. doi: 10.2131/jts.44.833. [PMID: 31813902]
  • Manuela Donalisio, Valeria Cagno, Andrea Civra, Davide Gibellini, Giuseppina Musumeci, Massimo Rittà, Manik Ghosh, David Lembo. The traditional use of Vachellia nilotica for sexually transmitted diseases is substantiated by the antiviral activity of its bark extract against sexually transmitted viruses. Journal of ethnopharmacology. 2018 Mar; 213(?):403-408. doi: 10.1016/j.jep.2017.11.039. [PMID: 29203273]
  • Zoi Piperigkou, Konstantina Karamanou, Nikolaos A Afratis, Panagiotis Bouris, Chrysostomi Gialeli, Celso L R Belmiro, Mauro S G Pavão, Dimitrios H Vynios, Aristidis M Tsatsakis. Biochemical and toxicological evaluation of nano-heparins in cell functional properties, proteasome activation and expression of key matrix molecules. Toxicology letters. 2016 Jan; 240(1):32-42. doi: 10.1016/j.toxlet.2015.10.005. [PMID: 26476401]
  • Yi Qian, Shuping Zhang, Wenli Guo, Juan Ma, Yue Chen, Lei Wang, Meirong Zhao, Sijin Liu. Polychlorinated biphenyls (PCBs) inhibit hepcidin expression through an estrogen-like effect associated with disordered systemic iron homeostasis. Chemical research in toxicology. 2015 Apr; 28(4):629-40. doi: 10.1021/tx500428r. [PMID: 25686467]
  • Elif Küpeli, Gaye Ulubay, Ilgaz Doğrul, Özlem Birben, Pınar Seyfettin, Aylin Özsancak Uğurlu, Füsun Öner Eyüboğlu, Mehmet Haberal. Long-term risk of pulmonary embolism in solid-organ transplant recipients. Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation. 2015 Apr; 13 Suppl 1(?):223-7. doi: . [PMID: 25894159]
  • Marta Correia-da-Silva, Emília Sousa, Bárbara Duarte, Franklim Marques, Félix Carvalho, Luís M Cunha-Ribeiro, Madalena M M Pinto. Flavonoids with an oligopolysulfated moiety: a new class of anticoagulant agents. Journal of medicinal chemistry. 2011 Jan; 54(1):95-106. doi: 10.1021/jm1013117. [PMID: 21138266]
  • Jianshe Lang, Ning Yang, Jiejie Deng, Kangtai Liu, Peng Yang, Guigen Zhang, Chengyu Jiang. Inhibition of SARS pseudovirus cell entry by lactoferrin binding to heparan sulfate proteoglycans. PloS one. 2011; 6(8):e23710. doi: 10.1371/journal.pone.0023710. [PMID: 21887302]
  • T B Di Giacomo, T P Hussein, D G Souza, P R Criado. Frequency of thrombophilia determinant factors in patients with livedoid vasculopathy and treatment with anticoagulant drugs--a prospective study. Journal of the European Academy of Dermatology and Venereology : JEADV. 2010 Nov; 24(11):1340-6. doi: 10.1111/j.1468-3083.2010.03646.x. [PMID: 20337814]
  • Lunyin Yu, Hari G Garg, Boyangzi Li, Robert J Linhardt, Charles A Hales. Antitumor effect of butanoylated heparin with low anticoagulant activity on lung cancer growth in mice and rats. Current cancer drug targets. 2010 Mar; 10(2):229-41. doi: 10.2174/156800910791054176. [PMID: 20201787]
  • Y Zhang, Z Hua, K Zhang, K Meng, Y Hu. Therapeutic effects of anticoagulant agents on preeclampsia in a murine model induced by phosphatidylserine/phosphatidylcholine microvesicles. Placenta. 2009 Dec; 30(12):1065-70. doi: 10.1016/j.placenta.2009.09.004. [PMID: 19837457]
  • Tomi Niemi, Marja Silvasti-Lundell, Elina Armstrong, Juha Hernesniemi. The Janus face of thromboprophylaxis in patients with high risk for both thrombosis and bleeding during intracranial surgery: report of five exemplary cases. Acta neurochirurgica. 2009 Oct; 151(10):1289-94. doi: 10.1007/s00701-009-0419-x. [PMID: 19513580]
  • Hiroyuki Kobinata, Mamoru Yamamoto, Seiji Ishikawa, Tokujiro Uchida, Koichi Nakazawa, Koshi Makita. [Case of anosmia which appeared after anaphylactic shock due to intravenous heparin]. Masui. The Japanese journal of anesthesiology. 2009 Aug; 58(8):997-9. doi: NULL. [PMID: 19702217]
  • Patrick J Shaw, Aaron M Fullerton, Michael A Scott, Patricia E Ganey, Robert A Roth. The role of the hemostatic system in murine liver injury induced by coexposure to lipopolysaccharide and trovafloxacin, a drug with idiosyncratic liability. Toxicology and applied pharmacology. 2009 May; 236(3):293-300. doi: 10.1016/j.taap.2009.01.018. [PMID: 19367693]
  • Kenji Suda, Masahiko Mastumoto, Setsuko Miyanishi. Intermittent heparin infusion in children with ischemic heart disease caused by Kawasaki disease. International journal of cardiology. 2009 Apr; 133(3):417-9. doi: 10.1016/j.ijcard.2007.12.021. [PMID: 18243369]
  • Robert Kramer, Payson Oberg-Higgins, Louis Russo, John H Braxton. Heparin-induced thrombocytopenia with thrombosis syndrome managed with plasmapheresis. Interactive cardiovascular and thoracic surgery. 2009 Apr; 8(4):439-41. doi: 10.1510/icvts.2008.193177. [PMID: 19129243]
  • Wei Zou, Sachin S Devi, Erica Sparkenbaugh, Husam S Younis, Robert A Roth, Patricia E Ganey. Hepatotoxic interaction of sulindac with lipopolysaccharide: role of the hemostatic system. Toxicological sciences : an official journal of the Society of Toxicology. 2009 Mar; 108(1):184-93. doi: 10.1093/toxsci/kfn259. [PMID: 19074762]
  • Weijun Luo, Hailu Shitaye, Michael Friedman, Christina N Bennett, Joshua Miller, Ormond A Macdougald, Kurt D Hankenson. Disruption of cell-matrix interactions by heparin enhances mesenchymal progenitor adipocyte differentiation. Experimental cell research. 2008 Nov; 314(18):3382-91. doi: 10.1016/j.yexcr.2008.07.003. [PMID: 18674534]
  • Wataru Abe, Kenichi Ikejima, Tie Lang, Kyoko Okumura, Nobuyuki Enomoto, Tsuneo Kitamura, Yoshiyuki Takei, Nobuhiro Sato. Low molecular weight heparin prevents hepatic fibrogenesis caused by carbon tetrachloride in the rat. Journal of hepatology. 2007 Feb; 46(2):286-94. doi: 10.1016/j.jhep.2006.08.023. [PMID: 17166617]
  • Nebojsa M Antonijevic, Nebojsa B Savic, Jovan Perunicic, Mirjana Kovac, Danijela Mikovic, Milica Stanojevic, Branko Calija, Rajko A Milosevic, Slobodan D Obradovic, Zorana Vasiljevic. Salvage late plasmapheresis in a patient with pulmonary embolism caused by heparin-induced thrombocytopenia primarily resistant to danaparoid sodium and lepirudin. Journal of clinical apheresis. 2006 Dec; 21(4):252-5. doi: 10.1002/jca.20099. [PMID: 16933276]
  • M P Reilly, S M Taylor, C Franklin, B S Sachais, D B Cines, K J Williams, S E McKenzie. Prothrombotic factors enhance heparin-induced thrombocytopenia and thrombosis in vivo in a mouse model. Journal of thrombosis and haemostasis : JTH. 2006 Dec; 4(12):2687-94. doi: 10.1111/j.1538-7836.2006.02201.x. [PMID: 16961586]
  • Wencai Li, Jinsheng Zhang, Quangcun Huang, Hongguang Zhu, Xuerong Zhang. Long-term administering low anticoagulant activity heparin can lessen rat hepatic fibrosis induced by either CCl(4) or porcine serum injection. Hepatology research : the official journal of the Japan Society of Hepatology. 2006 Oct; 36(2):115-23. doi: 10.1016/j.hepres.2006.07.004. [PMID: 16904936]
  • María A Campanero-Rhodes, Margarita Menéndez, José L Saiz, Libia Sanz, Juan J Calvete, Dolores Solís. Zinc ions induce the unfolding and self-association of boar spermadhesin PSP-I, a protein with a single CUB domain architecture, and promote its binding to heparin. Biochemistry. 2006 Jul; 45(27):8227-35. doi: 10.1021/bi052621g. [PMID: 16819821]
  • James P Luyendyk, Lois D Lehman-McKeeman, David M Nelson, Vasanthi M Bhaskaran, Timothy P Reilly, Bruce D Car, Glenn H Cantor, Xiaomin Deng, Jane F Maddox, Patricia E Ganey, Robert A Roth. Coagulation-dependent gene expression and liver injury in rats given lipopolysaccharide with ranitidine but not with famotidine. The Journal of pharmacology and experimental therapeutics. 2006 May; 317(2):635-43. doi: 10.1124/jpet.105.096305. [PMID: 16401727]
  • Hadef Skouri, Raoudha Gandouz, Saoussen Abroug, Imen Kraiem, Henda Euch, Jalel Gargouri, Abdelaziz Harbi. A prospective study of the prevalence of heparin-induced antibodies and other associated thromboembolic risk factors in pediatric patients undergoing hemodialysis. American journal of hematology. 2006 May; 81(5):328-34. doi: 10.1002/ajh.20614. [PMID: 16628723]
  • Niels H H Heegaard, Steen I Hansen, Jan Holm. A novel specific heparin-binding activity of bovine folate-binding protein characterized by capillary electrophoresis. Electrophoresis. 2006 Mar; 27(5-6):1122-7. doi: 10.1002/elps.200500719. [PMID: 16470783]
  • P R Deepa, P Varalakshmi. Influence of a low-molecular-weight heparin derivative on the nitric oxide levels and apoptotic DNA damage in adriamycin-induced cardiac and renal toxicity. Toxicology. 2006 Jan; 217(2-3):176-83. doi: 10.1016/j.tox.2005.09.009. [PMID: 16242830]
  • Orhan Kursat Poyrazoglu, Ayhan Dogukan, Mehmet Yalniz, Dilara Seckin, Ali Lhsan Gunal. Acute effect of standard heparin versus low molecular weight heparin on oxidative stress and inflammation in hemodialysis patients. Renal failure. 2006; 28(8):723-7. doi: 10.1080/08860220600925594. [PMID: 17162433]
  • Xijie Yu, Omar A Ibrahimi, Regina Goetz, Fuming Zhang, Siobhan I Davis, Holly J Garringer, Robert J Linhardt, David M Ornitz, Moosa Mohammadi, Kenneth E White. Analysis of the biochemical mechanisms for the endocrine actions of fibroblast growth factor-23. Endocrinology. 2005 Nov; 146(11):4647-56. doi: 10.1210/en.2005-0670. [PMID: 16081635]
  • Michel Baum, Susan Schiavi, Vangipuram Dwarakanath, Raymond Quigley. Effect of fibroblast growth factor-23 on phosphate transport in proximal tubules. Kidney international. 2005 Sep; 68(3):1148-53. doi: 10.1111/j.1523-1755.2005.00506.x. [PMID: 16105045]
  • Monika Maciejczyk-Pencuła, Grzegorz Polak, Jan Kotarski. Serum acute phase protein concentrations after hysterectomy with and without low-molecular-weight heparin thrombosis prophylaxis. Acta obstetricia et gynecologica Scandinavica. 2005 Aug; 84(8):752-5. doi: 10.1111/j.0001-6349.2005.00722.x. [PMID: 16026400]
  • Menno V Huisman, Henri Bounameaux. Treating patients with venous thromboembolism: initial strategies and long-term secondary prevention. Seminars in vascular medicine. 2005 Aug; 5(3):276-84. doi: 10.1055/s-2005-916167. [PMID: 16123915]
  • A M Visser, M C Kappers-Klunne, J J Cornelissen, M J van den Bent, W Taal. [A patient with sinus thrombosis associated with paroxysmal nocturnal hemoglobinuria]. Nederlands tijdschrift voor geneeskunde. 2005 Jul; 149(27):1528-32. doi: NULL. [PMID: 16032999]
  • A S Mathis, V Rao. Deep vein thrombosis during rabbit antithymocyte globulin administration. Transplantation proceedings. 2004 Dec; 36(10):3250-1. doi: 10.1016/j.transproceed.2004.09.086. [PMID: 15686740]
  • L-A Smith, M Harkness. A case of two adverse reactions. Postgraduate medical journal. 2004 Aug; 80(946):484-6. doi: 10.1136/pgmj.2003.017020. [PMID: 15299161]
  • Tatsuyuki Hayashi, Yuki Suyama, Mitsunobu Kaneko, Juri Okamura, Yutaka Nakao, Yasunobu Nonaka, Takeo Nomura. Heparin-induced thrombocytopenia and thrombosis in a patient with polycythemia vera. Internal medicine (Tokyo, Japan). 2004 Jul; 43(7):587-9. doi: 10.2169/internalmedicine.43.587. [PMID: 15335186]
  • Shinobu Miyazawa, Osamu Hotta, Naoko Doi, Yumiko Natori, Kiyotaka Nishikawa, Yasuhiro Natori. Role of mast cells in the development of renal fibrosis: use of mast cell-deficient rats. Kidney international. 2004 Jun; 65(6):2228-37. doi: 10.1111/j.1523-1755.2004.00629.x. [PMID: 15149336]
  • Omar A Ibrahimi, Fuming Zhang, Sybil C Lang Hrstka, Moosa Mohammadi, Robert J Linhardt. Kinetic model for FGF, FGFR, and proteoglycan signal transduction complex assembly. Biochemistry. 2004 Apr; 43(16):4724-30. doi: 10.1021/bi0352320. [PMID: 15096041]
  • L Kristin Newby, Manjushri V Bhapkar, Harvey D White, David J Moliterno, Nancy M Allen LaPointe, David E Kandzari, Freek W A Verheugt, Judith M Kramer, Paul W Armstrong, Robert M Califf. Aspirin use post-acute coronary syndromes: intolerance, bleeding and discontinuation. Journal of thrombosis and thrombolysis. 2003 Dec; 16(3):119-28. doi: 10.1023/b:thro.0000024050.78728.35. [PMID: 15087598]
  • P R Deepa, P Varalakshmi. Protective effect of low molecular weight heparin on oxidative injury and cellular abnormalities in adriamycin-induced cardiac and hepatic toxicity. Chemico-biological interactions. 2003 Oct; 146(2):201-10. doi: 10.1016/j.cbi.2003.08.003. [PMID: 14597133]
  • H J Ng, L P Koh, L H Lee. Successful control of postsurgical bleeding by recombinant factor VIIa in a renal failure patient given low molecular weight heparin and aspirin. Annals of hematology. 2003 Apr; 82(4):257-8. doi: 10.1007/s00277-003-0633-1. [PMID: 12707733]
  • Quan Dong Nguyen, Diana Van Do, Gilbert T Feke, Zareh Nazareth Demirjian, Kameran Lashkari. Heparin-induced antiheparin-platelet antibody associated with retinal venous thrombosis. Ophthalmology. 2003 Mar; 110(3):600-3. doi: 10.1016/s0161-6420(02)01766-9. [PMID: 12623829]
  • R V Thomas, H Bessos, M L Turner, E H Horn, C A Ludlam. The successful use of plasma exchange and immunosuppression in the management of acquired Glanzmann's thrombasthenia. British journal of haematology. 2002 Dec; 119(3):878-80. doi: 10.1046/j.1365-2141.2002.03870_4.x. [PMID: 12437677]
  • Britt-Marie Loo, Markku Salmivirta. Heparin/Heparan sulfate domains in binding and signaling of fibroblast growth factor 8b. The Journal of biological chemistry. 2002 Sep; 277(36):32616-23. doi: 10.1074/jbc.m204961200. [PMID: 12077148]
  • Tetsuo Yamashita, Morichika Konishi, Ayumi Miyake, Ken-ichi Inui, Nobuyuki Itoh. Fibroblast growth factor (FGF)-23 inhibits renal phosphate reabsorption by activation of the mitogen-activated protein kinase pathway. The Journal of biological chemistry. 2002 Aug; 277(31):28265-70. doi: 10.1074/jbc.m202527200. [PMID: 12032146]
  • Nick R Bijsterveld, Arno H Moons, Joost C M Meijers, Jan G P Tijssen, Harry R Büller, Marcel Levi, Ron J G Peters. Rebound thrombin generation after heparin therapy in unstable angina. A randomized comparison between unfractionated and low-molecular-weight heparin. Journal of the American College of Cardiology. 2002 Mar; 39(5):811-7. doi: 10.1016/s0735-1097(01)01825-3. [PMID: 11869846]
  • Markus Schmugge, Lorenz Risch, Andreas R Huber, Anne Benn, Joachim E Fischer. Heparin-induced thrombocytopenia-associated thrombosis in pediatric intensive care patients. Pediatrics. 2002 Jan; 109(1):E10. doi: 10.1542/peds.109.1.e10. [PMID: 11773578]
  • Anil K Saxena, B R Panhotra, Mohammed Naguib. Sudden irreversible sensory-neural hearing loss in a patient with diabetes receiving amikacin as an antibiotic-heparin lock. Pharmacotherapy. 2002 Jan; 22(1):105-8. doi: 10.1592/phco.22.1.105.33507. [PMID: 11794420]
  • P Weyrich, B Balletshofer, S Hoeft, H U Häring, P P Nawroth. Acute adrenocortical insufficiency due to heparin-induced thrombocytopenia with subsequent bilateral haemorrhagic infarction of the adrenal glands. VASA. Zeitschrift fur Gefasskrankheiten. 2001 Nov; 30(4):285-8. doi: 10.1024/0301-1526.30.4.285. [PMID: 11771214]
  • L T Busby, A Weyman, G M Rodgers. Excessive anticoagulation in patients with mild renal insufficiency receiving long-term therapeutic enoxaparin. American journal of hematology. 2001 May; 67(1):54-6. doi: 10.1002/ajh.1077. [PMID: 11279659]
  • S Benchetrit, E Golan, E Podjarny, J Green, G Rashid, J Bernheim, R Hershkovitz, J Bernheim. Low molecular weight heparin reduces proteinuria and modulates glomerular TNF-alpha production in the early phase of adriamycin nephropathy. Nephron. 2001 Feb; 87(2):155-60. doi: 10.1159/000045905. [PMID: 11244311]
  • Y Ishikawa, T Konta, M Kitamura. Spontaneous shift in transcriptional profile of explanted glomeruli via activation of the MAP kinase family. American journal of physiology. Renal physiology. 2000 Nov; 279(5):F954-9. doi: 10.1152/ajprenal.2000.279.5.f954. [PMID: 11053056]
  • V H Thourani, S S Brar, T P Kennedy, L R Thornton, J A Watts, R S Ronson, Z Q Zhao, A L Sturrock, J R Hoidal, J Vinten-Johansen. Nonanticoagulant heparin inhibits NF-kappaB activation and attenuates myocardial reperfusion injury. American journal of physiology. Heart and circulatory physiology. 2000 Jun; 278(6):H2084-93. doi: 10.1152/ajpheart.2000.278.6.h2084. [PMID: 10843908]
  • J D Berná, I Zuazu, M Madrigal, V García-Medina, C Fernández, F Guirado. Conservative treatment of large rectus sheath hematoma in patients undergoing anticoagulant therapy. Abdominal imaging. 2000 May; 25(3):230-4. doi: 10.1007/s002610000007. [PMID: 10823439]
  • S Ait Ben Ali, S Hilmani, M Choukri, A Sami, A El Azhari, M Achouri, A Ouboukhlik, A El Kamar, M Boucetta. [Multiple cerebral hydatic cysts of cardiac origin. A case report]. Neuro-Chirurgie. 1999 Dec; 45(5):426-9. doi: NULL. [PMID: 10717596]
  • W Jy, W W Mao, L L Horstman, P A Valant, Y S Ahn. A flow cytometric assay of platelet activation marker P-selectin (CD62P) distinguishes heparin-induced thrombocytopenia (HIT) from HIT with thrombosis (HITT). Thrombosis and haemostasis. 1999 Oct; 82(4):1255-9. doi: 10.1055/s-0037-1614371. [PMID: 10544909]
  • H Stricker, G Mombelli. [Skin necroses, thrombocytopenia and deep venous thrombosis in subcutaneous thromboembolism prophylaxis with heparin: heparin-induced thrombocytopenia (HIT) type II]. Therapeutische Umschau. Revue therapeutique. 1999 Sep; 56(9):484-6. doi: 10.1024/0040-5930.56.9.484. [PMID: 10517114]
  • A Oksa, P Pontuch, H Kratochvilova. [The effect of glycosaminoglycan sulodexide on albuminuria in patients with diabetes mellitus]. Bratislavske lekarske listy. 1999 Sep; 100(9):486-9. doi: NULL. [PMID: 10645038]
  • P Poullin, P A Pietri, P Lefèvre. [Heparin-induced thrombopenia: rapid regression of thrombopenia and thrombosis after plasma exchange. Case report]. La Revue de medecine interne. 1998 Nov; 19(11):819-22. doi: 10.1016/s0248-8663(98)80386-x. [PMID: 9864780]
  • P Poullin, P A Pietri, P Lefèvre. Heparin-induced thrombocytopenia with thrombosis: successful treatment with plasma exchange. British journal of haematology. 1998 Jul; 102(2):630-1. doi: 10.1046/j.1365-2141.1998.0847b.x. [PMID: 9695986]
  • Y Seki, H Takahashi, Y Aizawa. [Hemostatic evaluation of a patient with haloperidol-induced neuroleptic malignant syndrome associated with disseminated intravascular coagulation]. [Rinsho ketsueki] The Japanese journal of clinical hematology. 1998 May; 39(5):374-8. doi: NULL. [PMID: 9637888]
  • A Chen, L F Sheu, Y S Ho, Y F Lin, W Y Chou, J Y Wang, W H Lee. Administration of dexamethasone induces proteinuria of glomerular origin in mice. American journal of kidney diseases : the official journal of the National Kidney Foundation. 1998 Mar; 31(3):443-52. doi: 10.1053/ajkd.1998.v31.pm9506681. [PMID: 9506681]
  • U Hedin, G Daum, A W Clowes. Heparin inhibits thrombin-induced mitogen-activated protein kinase signaling in arterial smooth muscle cells. Journal of vascular surgery. 1998 Mar; 27(3):512-20. doi: 10.1016/s0741-5214(98)70326-x. [PMID: 9546238]
  • T E Warkentin, L J Elavathil, C P Hayward, M A Johnston, J I Russett, J G Kelton. The pathogenesis of venous limb gangrene associated with heparin-induced thrombocytopenia. Annals of internal medicine. 1997 Nov; 127(9):804-12. doi: 10.7326/0003-4819-127-9-199711010-00005. [PMID: 9382401]
  • D Ganzer, A Gutezeit, G Mayer, A Greinacher, P Eichler. [Prevention of thromboembolism as a cause of thromboembolic complications. A study of the incidence of heparin-induced thrombocytopenia type II]. Zeitschrift fur Orthopadie und ihre Grenzgebiete. 1997 Nov; 135(6):543-9. doi: 10.1055/s-2008-1039743. [PMID: 9499523]
  • M Antczak-Marczak, P Kuna. [The influence of heparin on histamine level in plasma during the early reaction phase of asthma]. Polskie Archiwum Medycyny Wewnetrznej. 1997 Jan; 97(1):7-14. doi: NULL. [PMID: 9235556]
  • H Engelberg. Evidence that endogenous heparin activity deficiency may be an important factor in atherogenesis. Seminars in thrombosis and hemostasis. 1997; 23(2):159-66. doi: 10.1055/s-2007-996085. [PMID: 9200341]
  • O Moen, K Høgåsen, E Fosse, E Dregelid, V Brockmeier, P Venge, M Harboe, T E Mollnes. Attenuation of changes in leukocyte surface markers and complement activation with heparin-coated cardiopulmonary bypass. The Annals of thoracic surgery. 1997 Jan; 63(1):105-11. doi: 10.1016/s0003-4975(96)00743-6. [PMID: 8993250]
  • M Kalinowski, K Pawlak, M Myśliwiec, A Popławski. [Use of low-molecular weight heparin during hemodialysis]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego. 1997 Jan; 2(9):208-10. doi: NULL. [PMID: 10907031]
  • L O Lathan, S L Staggers. Ancrod: the use of snake venom in the treatment of patients with heparin-induced thrombocytopenia and thrombosis undergoing coronary artery bypass grafting: nursing management. Heart & lung : the journal of critical care. 1996 Nov; 25(6):451-60; quiz 461. doi: 10.1016/s0147-9563(96)80046-x. [PMID: 8950124]
  • H M Olsen, C R Parish, J G Altin. Histidine-rich glycoprotein binding to T-cell lines and its effect on T-cell substratum adhesion is strongly potentiated by zinc. Immunology. 1996 Jun; 88(2):198-206. doi: 10.1111/j.1365-2567.1996.tb00005.x. [PMID: 8690451]
  • F P Peters, P A Doevendans, F L Erdkamp, F W Van Der Ent, F De Heer. Low molecular weight heparin-induced thrombocytopenia and thrombosis. European journal of haematology. 1996 May; 56(5):329-30. doi: 10.1111/j.1600-0609.1996.tb00726.x. [PMID: 8641411]
  • F Renaud, S Desset, L Oliver, G Gimenez-Gallego, E Van Obberghen, Y Courtois, M Laurent. The neurotrophic activity of fibroblast growth factor 1 (FGF1) depends on endogenous FGF1 expression and is independent of the mitogen-activated protein kinase cascade pathway. The Journal of biological chemistry. 1996 Feb; 271(5):2801-11. doi: 10.1074/jbc.271.5.2801. [PMID: 8576258]
  • M H El Habbal, L Smith, M J Elliott, S Strobel. Effect of heparin anticoagulation on neutrophil adhesion molecules and release of IL8: C3 is not essential. Cardiovascular research. 1995 Nov; 30(5):676-81. doi: 10.1016/0008-6363(95)00069-0. [PMID: 8595612]
  • D Jellinek, L S Green, C Bell, C K Lynott, N Gill, C Vargeese, G Kirschenheuter, D P McGee, P Abesinghe, W A Pieken. Potent 2'-amino-2'-deoxypyrimidine RNA inhibitors of basic fibroblast growth factor. Biochemistry. 1995 Sep; 34(36):11363-72. doi: 10.1021/bi00036a009. [PMID: 7547864]
  • NULL. Randomized trial of intravenous heparin versus recombinant hirudin for acute coronary syndromes. The Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) IIa Investigators. Circulation. 1994 Oct; 90(4):1631-7. doi: 10.1161/01.cir.90.4.1631. [PMID: 7923645]
  • H A Heck, C L Lutcher, D G Falls. Fatal thrombocytopenic coagulopathy after cardiopulmonary bypass: clinicopathologic correlations implicating heparin. Southern medical journal. 1994 Aug; 87(8):789-93. doi: 10.1097/00007611-199408000-00004. [PMID: 8052884]
  • A K Cheung, B Faezi-Jenkin, J K Leypoldt. Effect of thrombosis on complement activation and neutrophil degranulation during in vitro hemodialysis. Journal of the American Society of Nephrology : JASN. 1994 Jul; 5(1):110-5. doi: 10.1681/asn.v51110. [PMID: 7948777]
  • S J Lamme, P D de Rooij, P C Huijgens, J A Rauwerda. [The HITT syndrome: heparin-induced thrombocytopenia and thrombosis as a cause of paradoxically occurring thromboembolisms]. Nederlands tijdschrift voor geneeskunde. 1994 Jan; 138(4):189-93. doi: NULL. [PMID: 8107919]
  • G P Visentin, S E Ford, J P Scott, R H Aster. Antibodies from patients with heparin-induced thrombocytopenia/thrombosis are specific for platelet factor 4 complexed with heparin or bound to endothelial cells. The Journal of clinical investigation. 1994 Jan; 93(1):81-8. doi: 10.1172/jci116987. [PMID: 8282825]
  • R M Lidón, P Théroux, D Robitaille. Antithrombin-III plasma activity during and after prolonged use of heparin in unstable angina. Thrombosis research. 1993 Oct; 72(1):23-32. doi: 10.1016/0049-3848(93)90169-o. [PMID: 8122184]
  • D L Somers, C Sotolongo, J A Bertolatus. White clot syndrome associated with renal failure. Journal of the American Society of Nephrology : JASN. 1993 Aug; 4(2):137-41. doi: 10.1681/asn.v42137. [PMID: 8400075]
  • L R Toupin, D G Blanchard. Acute anuric renal failure: a complication of combined thrombolytic and antithrombotic therapy. International journal of cardiology. 1993 Jul; 40(3):283-5. doi: 10.1016/0167-5273(93)90012-6. [PMID: 8225663]
  • J Floege, E Eng, B A Young, W G Couser, R J Johnson. Heparin suppresses mesangial cell proliferation and matrix expansion in experimental mesangioproliferative glomerulonephritis. Kidney international. 1993 Feb; 43(2):369-80. doi: 10.1038/ki.1993.55. [PMID: 8441232]
  • G M Vogel, R G van Amsterdam, W J Kop, D G Meuleman. Pentasaccharide and Orgaran arrest, whereas heparin delays thrombus formation in a rat arteriovenous shunt. Thrombosis and haemostasis. 1993 Jan; 69(1):29-34. doi: 10.1055/s-0038-1651543. [PMID: 8446935]
  • G Castaman, M Ruggeri, R Girardello, F Rodeghiero. An unusually prolonged case of heparin-induced thrombocytopenia and disseminated intravascular coagulation. Haematologica. 1992 Mar; 77(2):174-6. doi: NULL. [PMID: 1398304]
  • Y P Au, R D Kenagy, A W Clowes. Heparin selectively inhibits the transcription of tissue-type plasminogen activator in primate arterial smooth muscle cells during mitogenesis. The Journal of biological chemistry. 1992 Feb; 267(5):3438-44. doi: 10.1016/s0021-9258(19)50750-5. [PMID: 1310687]
  • A Greinacher, W Drost, I Michels, J Leitl, M Gottsmann, H J Kohl, M Glaser, C Mueller-Eckhardt. Heparin-associated thrombocytopenia: successful therapy with the heparinoid Org 10172 in a patient showing cross-reaction to LMW heparins. Annals of hematology. 1992 Jan; 64(1):40-2. doi: 10.1007/bf01811470. [PMID: 1310879]
  • V D Mohr, J Lenz. [Heparin-associated thrombocytopenia, thrombosis and embolism. Side effects of thromboembolism prevention with low molecular weight heparin enoxaparin?]. Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen. 1991 Sep; 62(9):686-90. doi: NULL. [PMID: 1660803]
  • P A Casthely, D Yoganathan, B Karyanis, M Salem, T Yoganathan, C Komer, M Uribe, S Sclafani, A Hudak. Histamine blockade and cardiovascular changes following heparin administration during cardiac surgery. Journal of cardiothoracic anesthesia. 1990 Dec; 4(6):711-4. doi: 10.1016/s0888-6296(09)90009-6. [PMID: 2131900]
  • S Storti, L Pagano, R Marra, A Grilli, G Falappa, A M De Gaetano, A M Ferrante, B Bizzi. Urokinase and AT-III concentrate treatment in inferior vena cava thrombosis associated with nephrotic syndrome. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis. 1990 Dec; 1(6):743-5. doi: NULL. [PMID: 2133253]
  • G Montalescot, W M Zapol, A Carvalho, D R Robinson, A Torres, E Lowenstein. Neutralization of low molecular weight heparin by polybrene prevents thromboxane release and severe pulmonary hypertension in awake sheep. Circulation. 1990 Nov; 82(5):1754-64. doi: 10.1161/01.cir.82.5.1754. [PMID: 2171807]
  • S J Teasdale, V J Zulys, T Mycyk, R J Baird, M F Glynn. Ancrod anticoagulation for cardiopulmonary bypass in heparin-induced thrombocytopenia and thrombosis. The Annals of thoracic surgery. 1989 Nov; 48(5):712-3. doi: 10.1016/0003-4975(89)90800-x. [PMID: 2818066]
  • J R Kappa, C A Fisher, V P Addonizio. Heparin-induced platelet activation: the role of thromboxane A2 synthesis and the extent of platelet granule release in two patients. Journal of vascular surgery. 1989 Apr; 9(4):574-9. doi: . [PMID: 2709525]
  • F Fourrier, A Marey, J P Muller, P Lestavel, J Goudemand, C Chopin. [Multiple thrombosis and thrombocytopenia due to heparin occurring after plasma exchange]. Presse medicale (Paris, France : 1983). 1989 Feb; 18(7):359. doi: NULL. [PMID: 2522633]
  • E Herrera, M A Lasunción, M Castro, D Gómez-Coronado, A Martín, G Quack. Studies with etofibrate in the rat. Part I: Effects on glycerol, free fatty acid and triacylglycerol metabolism. Biochimica et biophysica acta. 1988 Nov; 963(1):42-52. doi: 10.1016/0005-2760(88)90336-0. [PMID: 3179329]
  • H Stricker, B Lämmle, M Furlan, I Sulzer. Heparin-dependent in vitro aggregation of normal platelets by plasma of a patient with heparin-induced skin necrosis: specific diagnostic test for a rare side effect. The American journal of medicine. 1988 Nov; 85(5):721-4. doi: 10.1016/s0002-9343(88)80250-x. [PMID: 3189376]
  • J R Kappa, E D Cottrell, H D Berkowitz, C A Fisher, M Sobel, N Ellison, V P Addonizio. Carotid endarterectomy in patients with heparin-induced platelet activation: comparative efficacy of aspirin and iloprost (ZK36374). Journal of vascular surgery. 1987 May; 5(5):693-701. doi: NULL. [PMID: 2437338]