2-[[(4R)-4-[(3R,5S,7S,10S,13R,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid (BioDeep_00000896798)
代谢物信息卡片
化学式: C26H43NO5 (449.31410680000005)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(CCC(=O)NCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C
InChI: InChI=1S/C26H43NO5/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32)/t15-,16+,17-,18-,19?,20?,21+,24?,25+,26-/m1/s1
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Michelle L Manni, Victoria A Heinrich, Gregory J Buchan, James P O'Brien, Crystal Uvalle, Veronika Cechova, Adolf Koudelka, Dharti Ukani, Mohamad Rawas-Qalaji, Tim D Oury, Renee Hart, Madeline Ellgass, Steven J Mullett, Merritt L Fajt, Sally E Wenzel, Fernando Holguin, Bruce A Freeman, Stacy G Wendell. Nitroalkene fatty acids modulate bile acid metabolism and lung function in obese asthma.
Scientific reports.
2021 09; 11(1):17788. doi:
10.1038/s41598-021-96471-9. [PMID: 34493738] - Lele Cheng, Tao Chen, Manyun Guo, Peining Liu, Xiangrui Qiao, Yuanyuan Wei, Jianqing She, Bolin Li, Wen Xi, Juan Zhou, Zuyi Yuan, Yue Wu, Junhui Liu. Glycoursodeoxycholic acid ameliorates diet-induced metabolic disorders with inhibiting endoplasmic reticulum stress.
Clinical science (London, England : 1979).
2021 07; 135(14):1689-1706. doi:
10.1042/cs20210198. [PMID: 34236076] - Lien Van den Bossche, Pieter Hindryckx, Lindsey Devisscher, Sarah Devriese, Sophie Van Welden, Tom Holvoet, Ramiro Vilchez-Vargas, Marius Vital, Dietmar H Pieper, Julie Vanden Bussche, Lynn Vanhaecke, Tom Van de Wiele, Martine De Vos, Debby Laukens. Ursodeoxycholic Acid and Its Taurine- or Glycine-Conjugated Species Reduce Colitogenic Dysbiosis and Equally Suppress Experimental Colitis in Mice.
Applied and environmental microbiology.
2017 04; 83(7):. doi:
10.1128/aem.02766-16. [PMID: 28115375] - Shyamchand Mayengbam, James D House, Michel Aliani. Investigation of vitamin B₆ inadequacy, induced by exposure to the anti-B₆ factor 1-amino D-proline, on plasma lipophilic metabolites of rats: a metabolomics approach.
European journal of nutrition.
2016 Apr; 55(3):1213-23. doi:
10.1007/s00394-015-0934-x. [PMID: 26009005] - Mark Mapstone, Amrita K Cheema, Massimo S Fiandaca, Xiaogang Zhong, Timothy R Mhyre, Linda H MacArthur, William J Hall, Susan G Fisher, Derick R Peterson, James M Haley, Michael D Nazar, Steven A Rich, Dan J Berlau, Carrie B Peltz, Ming T Tan, Claudia H Kawas, Howard J Federoff. Plasma phospholipids identify antecedent memory impairment in older adults.
Nature medicine.
2014 Apr; 20(4):415-8. doi:
10.1038/nm.3466. [PMID: 24608097] - Maria A Brito, Sílvia Lima, Adelaide Fernandes, Ana S Falcão, Rui F M Silva, D Allan Butterfield, Dora Brites. Bilirubin injury to neurons: contribution of oxidative stress and rescue by glycoursodeoxycholic acid.
Neurotoxicology.
2008 Mar; 29(2):259-69. doi:
10.1016/j.neuro.2007.11.002. [PMID: 18164405] - B L Strom, R D Soloway, J Rios-Dalenz, H A Rodriguez-Martinez, S L West, J L Kinman, R S Crowther, D Taylor, M Polansky, J A Berlin. Biochemical epidemiology of gallbladder cancer.
Hepatology (Baltimore, Md.).
1996 Jun; 23(6):1402-11. doi:
10.1002/hep.510230616. [PMID: 8675157] - A Roda, E Roda, E Marchi, P Simoni, C Cerrè, A Pistillo, C Polimeni. Improved intestinal absorption of an enteric-coated sodium ursodeoxycholate formulation.
Pharmaceutical research.
1994 May; 11(5):642-7. doi:
10.1023/a:1018907825281. [PMID: 8058630] - C Marteau, H Portugal, S Mathieu, A M Pauli, A Gérolami. Effect of various bile salts on calcium concentration and calcium carbonate saturation of rat bile.
Journal of hepatology.
1988 Aug; 7(1):57-62. doi:
10.1016/s0168-8278(88)80506-3. [PMID: 3183351]