(3-Carboxy-2-octanoyloxypropyl)-trimethylazanium (BioDeep_00000896750)

   


代谢物信息卡片


(3-Carboxy-2-octanoyloxypropyl)-trimethylazanium

化学式: C15H30NO4+ (288.217472)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCCCC(=O)OC(CC(=O)O)C[N+](C)(C)C
InChI: InChI=1S/C15H29NO4/c1-5-6-7-8-9-10-15(19)20-13(11-14(17)18)12-16(2,3)4/h13H,5-12H2,1-4H3/p+1

描述信息

同义名列表

1 个代谢物同义名

(3-Carboxy-2-octanoyloxypropyl)-trimethylazanium



数据库引用编号

2 个数据库交叉引用编号

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相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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INOH(0)

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0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Brian J Koos, Jeffrey A Gornbein. Early pregnancy metabolites predict gestational diabetes mellitus: implications for fetal programming. American journal of obstetrics and gynecology. 2021 02; 224(2):215.e1-215.e7. doi: 10.1016/j.ajog.2020.07.050. [PMID: 32739399]
  • Eugenio Zoni, Martina Minoli, Cédric Bovet, Anne Wehrhan, Salvatore Piscuoglio, Charlotte K Y Ng, Peter C Gray, Martin Spahn, George N Thalmann, Marianna Kruithof-de Julio. Preoperative plasma fatty acid metabolites inform risk of prostate cancer progression and may be used for personalized patient stratification. BMC cancer. 2019 Dec; 19(1):1216. doi: 10.1186/s12885-019-6418-2. [PMID: 31842810]
  • Yanhan Li, Ruoxin Zhu, Yi Liu, Jinqing Song, Jing Xu, Yanling Yang. Medium-chain acyl-coenzyme A dehydrogenase deficiency: Six cases in the Chinese population. Pediatrics international : official journal of the Japan Pediatric Society. 2019 Jun; 61(6):551-557. doi: 10.1111/ped.13872. [PMID: 31033143]
  • Jiwon Park, Yumi Shin, Tae Hyun Kim, Dong-Hyun Kim, Anbok Lee. Plasma metabolites as possible biomarkers for diagnosis of breast cancer. PloS one. 2019; 14(12):e0225129. doi: 10.1371/journal.pone.0225129. [PMID: 31794572]
  • Bjørn Waagsbø, Asbjørn Svardal, Thor Ueland, Linn Landrø, Olav Øktedalen, Rolf K Berge, Trude H Flo, Pål Aukrust, Jan K Damås. Low levels of short- and medium-chain acylcarnitines in HIV-infected patients. European journal of clinical investigation. 2016 May; 46(5):408-17. doi: 10.1111/eci.12609. [PMID: 26913383]
  • Minjoo Kim, Saem Jung, Sang-Hyun Lee, Jong Ho Lee. Association between arterial stiffness and serum L-octanoylcarnitine and lactosylceramide in overweight middle-aged subjects: 3-year follow-up study. PloS one. 2015; 10(3):e0119519. doi: 10.1371/journal.pone.0119519. [PMID: 25781947]
  • Anthony J Donato, Grant D Henson, Corey R Hart, Gwenael Layec, Joel D Trinity, R Colton Bramwell, Ryley A Enz, R Garrett Morgan, Kelly D Reihl, Sugata Hazra, Ashley E Walker, Russell S Richardson, Lisa A Lesniewski. The impact of ageing on adipose structure, function and vasculature in the B6D2F1 mouse: evidence of significant multisystem dysfunction. The Journal of physiology. 2014 Sep; 592(18):4083-96. doi: 10.1113/jphysiol.2014.274175. [PMID: 25038241]
  • Jan-Willem Schoonen, Vincent van Duinen, Amar Oedit, Paul Vulto, Thomas Hankemeier, Petrus W Lindenburg. Continuous-flow microelectroextraction for enrichment of low abundant compounds. Analytical chemistry. 2014 Aug; 86(16):8048-56. doi: 10.1021/ac500707v. [PMID: 24892382]
  • Réjane Morand, Massimiliano Donzelli, Manuel Haschke, Stephan Krähenbühl. Quantification of plasma carnitine and acylcarnitines by high-performance liquid chromatography-tandem mass spectrometry using online solid-phase extraction. Analytical and bioanalytical chemistry. 2013 Nov; 405(27):8829-36. doi: 10.1007/s00216-013-7309-z. [PMID: 23995505]
  • Attilio Naccarato, Sacha Moretti, Giovanni Sindona, Antonio Tagarelli. Identification and assay of underivatized urinary acylcarnitines by paper spray tandem mass spectrometry. Analytical and bioanalytical chemistry. 2013 Oct; 405(25):8267-76. doi: 10.1007/s00216-013-7232-3. [PMID: 23907684]
  • Anelise M Tonin, Mateus Grings, Lisiane A Knebel, Ângela Zanatta, Alana P Moura, César A J Ribeiro, Guilhian Leipnitz, Moacir Wajner. Disruption of redox homeostasis in cerebral cortex of developing rats by acylcarnitines accumulating in medium-chain acyl-CoA dehydrogenase deficiency. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2012 Aug; 30(5):383-90. doi: 10.1016/j.ijdevneu.2012.03.238. [PMID: 22472139]
  • David A Rudnick, Nicholas O Davidson. Functional Relationships between Lipid Metabolism and Liver Regeneration. International journal of hepatology. 2012; 2012(?):549241. doi: 10.1155/2012/549241. [PMID: 22319652]
  • Dominik Pesta, Florian Hoppel, Christian Macek, Hubert Messner, Martin Faulhaber, Conrad Kobel, Walther Parson, Martin Burtscher, Michael Schocke, Erich Gnaiger. Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans. American journal of physiology. Regulatory, integrative and comparative physiology. 2011 Oct; 301(4):R1078-87. doi: 10.1152/ajpregu.00285.2011. [PMID: 21775647]
  • Lena Burri, Bodil Bjørndal, Hege Wergedahl, Kjetil Berge, Pavol Bohov, Asbjørn Svardal, Rolf K Berge. Tetradecylthioacetic acid increases hepatic mitochondrial β-oxidation and alters fatty acid composition in a mouse model of chronic inflammation. Lipids. 2011 Aug; 46(8):679-89. doi: 10.1007/s11745-011-3536-2. [PMID: 21479675]
  • S Larsen, N Stride, M Hey-Mogensen, C N Hansen, J L Andersen, S Madsbad, D Worm, J W Helge, F Dela. Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes. Diabetologia. 2011 Jun; 54(6):1427-36. doi: 10.1007/s00125-011-2098-4. [PMID: 21424396]
  • Mette Skovbro, Robert Boushel, Christina Neigaard Hansen, Jørn Wulff Helge, Flemming Dela. High-fat feeding inhibits exercise-induced increase in mitochondrial respiratory flux in skeletal muscle. Journal of applied physiology (Bethesda, Md. : 1985). 2011 Jun; 110(6):1607-14. doi: 10.1152/japplphysiol.01341.2010. [PMID: 21415171]
  • Guy L Weinberg, Richard Ripper, Sarah Bern, Bocheng Lin, Lucas Edelman, Guido Digregorio, Mariann Piano, Douglas L Feinstein. Pioglitazone attenuates acute cocaine toxicity in rat isolated heart: potential protection by metabolic modulation. Anesthesiology. 2011 Jun; 114(6):1389-95. doi: 10.1097/aln.0b013e318218a7f6. [PMID: 21487283]
  • Hye In Woo, Hyung-Doo Park, Yong-Wha Lee, Dong Hwan Lee, Chang-Seok Ki, Soo-Youn Lee, Jong-Won Kim. Clinical, biochemical and genetic analyses in two Korean patients with medium-chain acyl-CoA dehydrogenase deficiency. The Korean journal of laboratory medicine. 2011 Jan; 31(1):54-60. doi: 10.3343/kjlm.2011.31.1.54. [PMID: 21239873]
  • Juliet Oerton, Javaria M Khalid, Guy Besley, R Neil Dalton, Melanie Downing, Anne Green, Mick Henderson, Steve Krywawych, James Leonard, Brage S Andresen, Carol Dezateux. Newborn screening for medium chain acyl-CoA dehydrogenase deficiency in England: prevalence, predictive value and test validity based on 1.5 million screened babies. Journal of medical screening. 2011; 18(4):173-81. doi: 10.1258/jms.2011.011086. [PMID: 22166308]
  • Shelley Kennedy, Beth K Potter, Kumanan Wilson, Lawrence Fisher, Michael Geraghty, Jennifer Milburn, Pranesh Chakraborty. The first three years of screening for medium chain acyl-CoA dehydrogenase deficiency (MCADD) by newborn screening ontario. BMC pediatrics. 2010 Nov; 10(?):82. doi: 10.1186/1471-2431-10-82. [PMID: 21083904]
  • Ronald J A Wanders, Jos P N Ruiter, Lodewijk IJLst, Hans R Waterham, Sander M Houten. The enzymology of mitochondrial fatty acid beta-oxidation and its application to follow-up analysis of positive neonatal screening results. Journal of inherited metabolic disease. 2010 Oct; 33(5):479-94. doi: 10.1007/s10545-010-9104-8. [PMID: 20490924]
  • Roman Yusupov, David N Finegold, Edwin W Naylor, Inderneel Sahai, Susan Waisbren, Harvey L Levy. Sudden death in medium chain acyl-coenzyme a dehydrogenase deficiency (MCADD) despite newborn screening. Molecular genetics and metabolism. 2010 Sep; 101(1):33-9. doi: 10.1016/j.ymgme.2010.05.007. [PMID: 20580581]
  • Joris Hoeks, Noud A van Herpen, Marco Mensink, Esther Moonen-Kornips, Denis van Beurden, Matthijs K C Hesselink, Patrick Schrauwen. Prolonged fasting identifies skeletal muscle mitochondrial dysfunction as consequence rather than cause of human insulin resistance. Diabetes. 2010 Sep; 59(9):2117-25. doi: 10.2337/db10-0519. [PMID: 20573749]
  • Rainer Lehmann, Xinjie Zhao, Cora Weigert, Perikles Simon, Elvira Fehrenbach, Jens Fritsche, Jürgen Machann, Fritz Schick, Jiangshan Wang, Miriam Hoene, Erwin D Schleicher, Hans-Ulrich Häring, Guowang Xu, Andreas M Niess. Medium chain acylcarnitines dominate the metabolite pattern in humans under moderate intensity exercise and support lipid oxidation. PloS one. 2010 Jul; 5(7):e11519. doi: 10.1371/journal.pone.0011519. [PMID: 20634953]
  • Emily H Smith, Cheryl Thomas, David McHugh, Dimitar Gavrilov, Kimiyo Raymond, Piero Rinaldo, Silvia Tortorelli, Dietrich Matern, W Edward Highsmith, Devin Oglesbee. Allelic diversity in MCAD deficiency: the biochemical classification of 54 variants identified during 5 years of ACADM sequencing. Molecular genetics and metabolism. 2010 Jul; 100(3):241-50. doi: 10.1016/j.ymgme.2010.04.001. [PMID: 20434380]
  • Walter E Gall, Kirk Beebe, Kay A Lawton, Klaus-Peter Adam, Matthew W Mitchell, Pamela J Nakhle, John A Ryals, Michael V Milburn, Monica Nannipieri, Stefania Camastra, Andrea Natali, Ele Ferrannini. alpha-hydroxybutyrate is an early biomarker of insulin resistance and glucose intolerance in a nondiabetic population. PloS one. 2010 May; 5(5):e10883. doi: 10.1371/journal.pone.0010883. [PMID: 20526369]
  • Hiroki Tsuchida, Naohiko Anzai, Ho J Shin, Michael F Wempe, Promsuk Jutabha, Atsushi Enomoto, Seok H Cha, Takeo Satoh, Masashi Ishida, Hiroyuki Sakurai, Hitoshi Endou. Identification of a novel organic anion transporter mediating carnitine transport in mouse liver and kidney. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 2010; 25(4-5):511-22. doi: 10.1159/000303060. [PMID: 20332632]
  • Min Sun Lee, Byung Hwa Jung, Bong Chul Chung, Sung Hee Cho, Ki Young Kim, Oh Seoung Kwon, Boya Nugraha, Young-Joo Lee. Metabolomics study with gas chromatography-mass spectrometry for predicting valproic acid-induced hepatotoxicity and discovery of novel biomarkers in rat urine. International journal of toxicology. 2009 Sep; 28(5):392-404. doi: 10.1177/1091581809340329. [PMID: 19605889]
  • E M Maier, J Pongratz, A C Muntau, B Liebl, U Nennstiel-Ratzel, U Busch, R Fingerhut, B Olgemöller, A A Roscher, W Röschinger. Dissection of biochemical borderline phenotypes in carriers and genetic variants of medium-chain acyl-CoA dehyrogenase deficiency: implications for newborn screening [corrected]. Clinical genetics. 2009 Aug; 76(2):179-87. doi: 10.1111/j.1399-0004.2009.01217.x. [PMID: 19780764]
  • Frank ter Veld, Martina Mueller, Simone Kramer, Ulrike Haussmann, Diran Herebian, Ertan Mayatepek, Maurice D Laryea, Sonja Primassin, Ute Spiekerkoetter. A novel tandem mass spectrometry method for rapid confirmation of medium- and very long-chain acyl-CoA dehydrogenase deficiency in newborns. PloS one. 2009 Jul; 4(7):e6449. doi: 10.1371/journal.pone.0006449. [PMID: 19649258]
  • Esther M Maier, Søren W Gersting, Kristina F Kemter, Johanna M Jank, Maria Reindl, Dunja D Messing, Marietta S Truger, Christian P Sommerhoff, Ania C Muntau. Protein misfolding is the molecular mechanism underlying MCADD identified in newborn screening. Human molecular genetics. 2009 May; 18(9):1612-23. doi: 10.1093/hmg/ddp079. [PMID: 19224950]
  • Paul E Minkler, Maria S K Stoll, Stephen T Ingalls, Shuming Yang, Janos Kerner, Charles L Hoppel. Quantification of carnitine and acylcarnitines in biological matrices by HPLC electrospray ionization-mass spectrometry. Clinical chemistry. 2008 Sep; 54(9):1451-62. doi: 10.1373/clinchem.2007.099226. [PMID: 18678604]
  • Julie H Rennison, Tracy A McElfresh, Isidore C Okere, Hiral V Patel, Amy B Foster, Kalpana K Patel, Maria S Stoll, Paul E Minkler, Hisashi Fujioka, Brian D Hoit, Martin E Young, Charles L Hoppel, Margaret P Chandler. Enhanced acyl-CoA dehydrogenase activity is associated with improved mitochondrial and contractile function in heart failure. Cardiovascular research. 2008 Jul; 79(2):331-40. doi: 10.1093/cvr/cvn066. [PMID: 18339649]
  • Gabriella A Horvath, A G F Davidson, Sylvia G Stockler-Ipsiroglu, Yolanda P Lillquist, Paula J Waters, S Olpin, B S Andresen, Jan Palaty, Judie Nelson, Hilary Vallance. Newborn screening for MCAD deficiency: experience of the first three years in British Columbia, Canada. Canadian journal of public health = Revue canadienne de sante publique. 2008 Jul; 99(4):276-80. doi: . [PMID: 18767270]
  • T G J Derks, T S Boer, A van Assen, T Bos, J Ruiter, H R Waterham, K E Niezen-Koning, R J A Wanders, J M M Rondeel, J G Loeber, L P Ten Kate, G P A Smit, D-J Reijngoud. Neonatal screening for medium-chain acyl-CoA dehydrogenase (MCAD) deficiency in The Netherlands: the importance of enzyme analysis to ascertain true MCAD deficiency. Journal of inherited metabolic disease. 2008 Feb; 31(1):88-96. doi: 10.1007/s10545-007-0492-3. [PMID: 18188679]
  • J M Khalid, J Oerton, M Cortina-Borja, B S Andresen, G Besley, R N Dalton, M Downing, A Green, M Henderson, J Leonard, C Dezateux. Ethnicity of children with homozygous c.985A>G medium-chain acyl-CoA dehydrogenase deficiency: findings from screening approximately 1.1 million newborn infants. Journal of medical screening. 2008; 15(3):112-7. doi: 10.1258/jms.2008.008043. [PMID: 18927092]
  • Kyoko Yokoi, Tetsuya Ito, Yasuhiro Maeda, Yoko Nakajima, Akihito Ueta, Takayasu Nomura, Norihisa Koyama, Ineko Kato, Satoshi Suzuki, Yukihisa Kurono, Naruji Sugiyama, Hajime Togari. Acylcarnitine profiles during carnitine loading and fasting tests in a Japanese patient with medium-chain acyl-CoA dehydrogenase deficiency. The Tohoku journal of experimental medicine. 2007 Dec; 213(4):351-9. doi: 10.1620/tjem.213.351. [PMID: 18075239]
  • L Santos, A Patterson, S M Moreea, C M Lippiatt, J Walter, M Henderson. Acute liver failure in pregnancy associated with maternal MCAD deficiency. Journal of inherited metabolic disease. 2007 Feb; 30(1):103. doi: 10.1007/s10545-006-0520-8. [PMID: 17186412]
  • H H Huidekoper, J Schneider, T Westphal, F M Vaz, M Duran, F A Wijburg. Prolonged moderate-intensity exercise without and with L-carnitine supplementation in patients with MCAD deficiency. Journal of inherited metabolic disease. 2006 Oct; 29(5):631-6. doi: 10.1007/s10545-006-0355-3. [PMID: 16972171]
  • William J Rhead. Newborn screening for medium-chain acyl-CoA dehydrogenase deficiency: a global perspective. Journal of inherited metabolic disease. 2006 Apr; 29(2-3):370-7. doi: 10.1007/s10545-006-0292-1. [PMID: 16763904]
  • Leigh Waddell, Veronica Wiley, Kevin Carpenter, Bruce Bennetts, Lyn Angel, Brage S Andresen, Bridget Wilcken. Medium-chain acyl-CoA dehydrogenase deficiency: genotype-biochemical phenotype correlations. Molecular genetics and metabolism. 2006 Jan; 87(1):32-9. doi: 10.1016/j.ymgme.2005.09.020. [PMID: 16291504]
  • D R de Assis, R C Maria, G C Ferreira, P F Schuck, A Latini, C S Dutra-Filho, C M D Wannmacher, A T S Wyse, M Wajner. Na+, K+ ATPase activity is markedly reduced by cis-4-decenoic acid in synaptic plasma membranes from cerebral cortex of rats. Experimental neurology. 2006 Jan; 197(1):143-9. doi: 10.1016/j.expneurol.2005.09.002. [PMID: 16203000]
  • Judit Bene, Katalin Komlósi, Beáta Gasztonyi, Márk Juhász, Zsolt Tulassay, Béla Melegh. Plasma carnitine ester profile in adult celiac disease patients maintained on long-term gluten free diet. World journal of gastroenterology. 2005 Nov; 11(42):6671-5. doi: 10.3748/wjg.v11.i42.6671. [PMID: 16425363]
  • Regina Ensenauer, Jennifer L Winters, Patricia A Parton, David F Kronn, Jong-Won Kim, Dietrich Matern, Piero Rinaldo, Si Houn Hahn. Genotypic differences of MCAD deficiency in the Asian population: novel genotype and clinical symptoms preceding newborn screening notification. Genetics in medicine : official journal of the American College of Medical Genetics. 2005 May; 7(5):339-43. doi: 10.1097/01.gim.0000164548.54482.9d. [PMID: 15915086]
  • Francisco A Moreno, Helen Macey, Brian Schreiber. Carnitine levels in valproic acid-treated psychiatric patients: a cross-sectional study. The Journal of clinical psychiatry. 2005 May; 66(5):555-8. doi: 10.4088/jcp.v66n0502. [PMID: 15986510]
  • P J Lee, E L Harrison, M G Jones, S Jones, J V Leonard, R A Chalmers. L-carnitine and exercise tolerance in medium-chain acyl-coenzyme A dehydrogenase (MCAD) deficiency: a pilot study. Journal of inherited metabolic disease. 2005; 28(2):141-52. doi: 10.1007/s10545-005-5262-5. [PMID: 15877203]
  • P Mueller, A Schulze, I Schindler, T Ethofer, P Buehrdel, U Ceglarek. Validation of an ESI-MS/MS screening method for acylcarnitine profiling in urine specimens of neonates, children, adolescents and adults. Clinica chimica acta; international journal of clinical chemistry. 2003 Jan; 327(1-2):47-57. doi: 10.1016/s0009-8981(02)00327-3. [PMID: 12482618]
  • K Carpenter, V Wiley, K G Sim, D Heath, B Wilcken. Evaluation of newborn screening for medium chain acyl-CoA dehydrogenase deficiency in 275 000 babies. Archives of disease in childhood. Fetal and neonatal edition. 2001 Sep; 85(2):F105-9. doi: 10.1136/fn.85.2.f105. [PMID: 11517203]
  • P E Minkler, C L Hoppel. Quantification of free carnitine, individual short- and medium-chain acylcarnitines, and total carnitine in plasma by high-performance liquid chromatography. Analytical biochemistry. 1993 Aug; 212(2):510-8. doi: 10.1006/abio.1993.1361. [PMID: 8214594]
  • J L Van Hove, W Zhang, S G Kahler, C R Roe, Y T Chen, N Terada, D H Chace, A K Iafolla, J H Ding, D S Millington. Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency: diagnosis by acylcarnitine analysis in blood. American journal of human genetics. 1993 May; 52(5):958-66. doi: NULL. [PMID: 8488845]
  • E Schmidt-Sommerfeld, D Penn, M Duran, M J Bennett, R Santer, C A Stanley. Detection of inborn errors of fatty acid oxidation from acylcarnitine analysis of plasma and blood spots with the radioisotopic exchange-high-performance liquid chromatographic method. The Journal of pediatrics. 1993 May; 122(5 Pt 1):708-14. doi: 10.1016/s0022-3476(06)80009-0. [PMID: 8496747]
  • E Schmidt-Sommerfeld, D Penn, P Rinaldo, D Kossak, B U Li, Z H Huang, D A Gage. Urinary medium-chain acylcarnitines in medium-chain acyl-CoA dehydrogenase deficiency, medium-chain triglyceride feeding and valproic acid therapy: sensitivity and specificity of the radioisotopic exchange/high performance liquid chromatography method. Pediatric research. 1992 Jun; 31(6):545-51. doi: 10.1203/00006450-199206000-00002. [PMID: 1635814]
  • J Farquharson, E C Jamieson, J Muir, F Cockburn, R W Logan. Direct gas chromatographic assay of urinary medium-chain fatty acylcarnitines by their thermal decomposition. Clinica chimica acta; international journal of clinical chemistry. 1992 Feb; 205(3):233-40. doi: 10.1016/0009-8981(92)90064-w. [PMID: 1576748]
  • A Marzo, E Arrigoni Martelli, A Mancinelli, G Cardace, C Corbelletta, E Bassani, M Solbiati. Protein binding of L-carnitine family components. European journal of drug metabolism and pharmacokinetics. 1991; Spec No 3(?):364-8. doi: . [PMID: 1820909]
  • E Schmidt-Sommerfeld, D Penn, J Kerner, L L Bieber, T M Rossi, E Lebenthal. Quantitation of urinary carnitine esters in a patient with medium-chain acyl-coenzyme A dehydrogenase deficiency: effect of metabolic state and L-carnitine therapy. The Journal of pediatrics. 1989 Oct; 115(4):577-82. doi: 10.1016/s0022-3476(89)80284-7. [PMID: 2795349]
  • D S Millington, C R Roe. Medium-chain acyl-CoA dehydrogenase deficiency. The New England journal of medicine. 1989 May; 320(18):1219. doi: 10.1056/nejm198905043201817. [PMID: 2710197]
  • C R Roe, D S Millington, D A Maltby, R B Wellman. Post-mortem recognition of inherited metabolic disorders from specific acylcarnitines in tissue in cases of sudden infant death. Lancet (London, England). 1987 Feb; 1(8531):512. doi: 10.1016/s0140-6736(87)92126-x. [PMID: 2881073]
  • C R Roe, D S Millington, D A Maltby, P Kinnebrew. Recognition of medium-chain acyl-CoA dehydrogenase deficiency in asymptomatic siblings of children dying of sudden infant death or Reye-like syndromes. The Journal of pediatrics. 1986 Jan; 108(1):13-8. doi: 10.1016/s0022-3476(86)80762-4. [PMID: 3944676]
  • M Duran, D Ketting, R van Vossen, T E Beckeringh, L Dorland, L Bruinvis, S K Wadman. Octanoylglucuronide excretion in patients with a defective oxidation of medium-chain fatty acids. Clinica chimica acta; international journal of clinical chemistry. 1985 Nov; 152(3):253-60. doi: 10.1016/0009-8981(85)90100-7. [PMID: 4064333]
  • M Duran, G Mitchell, J B de Klerk, J P de Jager, M Hofkamp, L Bruinvis, D Ketting, J M Saudubray, S K Wadman. Octanoic acidemia and octanoylcarnitine excretion with dicarboxylic aciduria due to defective oxidation of medium-chain fatty acids. The Journal of pediatrics. 1985 Sep; 107(3):397-404. doi: 10.1016/s0022-3476(85)80514-x. [PMID: 4032135]
  • C R Roe, D S Millington, D A Maltby, T P Bohan, S G Kahler, R A Chalmers. Diagnostic and therapeutic implications of medium-chain acylcarnitines in the medium-chain acyl-coA dehydrogenase deficiency. Pediatric research. 1985 May; 19(5):459-66. doi: 10.1203/00006450-198505000-00011. [PMID: 4000772]
  • D S Millington, T P Bohan, C R Roe, A L Yergey, D J Liberato. Valproylcarnitine: a novel drug metabolite identified by fast atom bombardment and thermospray liquid chromatography-mass spectrometry. Clinica chimica acta; international journal of clinical chemistry. 1985 Jan; 145(1):69-76. doi: 10.1016/0009-8981(85)90020-8. [PMID: 3919970]
  • R A Chalmers, C R Roe, T E Stacey, C L Hoppel. Urinary excretion of l-carnitine and acylcarnitines by patients with disorders of organic acid metabolism: evidence for secondary insufficiency of l-carnitine. Pediatric research. 1984 Dec; 18(12):1325-8. doi: 10.1203/00006450-198412000-00021. [PMID: 6441143]
  • C S Kim, D R Dorgan, C R Roe. L-carnitine: therapeutic strategy for metabolic encephalopathy. Brain research. 1984 Sep; 310(1):149-53. doi: 10.1016/0006-8993(84)90019-2. [PMID: 6478235]