(1R,2R)-cyclohexane-1,2-diamine;oxalic acid;platinum(2+) (BioDeep_00000896591)

   


代谢物信息卡片


(1R,2R)-cyclohexane-1,2-diamine;oxalic acid;platinum(2+)

化学式: C8H16N2O4Pt+2 (399.0758)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CCC(C(C1)N)N.C(=O)(C(=O)O)O.[Pt+2]
InChI: /q

描述信息

D000970 - Antineoplastic Agents

同义名列表

1 个代谢物同义名

(1R,2R)-cyclohexane-1,2-diamine;oxalic acid;platinum(2+)



数据库引用编号

1 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Matthew Ng, Sylvia Chen, Whee Sze Ong, Akhila Balachander, Amanda Seet, Joe Yeong, Natalia Sutiman, Tony Kiat Hon Lim, Bernett Lee, Yu Amanda Guo, Wai Fook Leong, Sze Sing Lee, Justina Lam, Su Pin Choo, Anders Jacobsen Skanderup, Subhra Kumar Biswas, David Tai, Balram Chowbay. A phase 1b study of OXIRI in pancreatic adenocarcinoma patients and its immunomodulatory effects. International journal of cancer. 2022 08; 151(3):435-449. doi: 10.1002/ijc.34021. [PMID: 35415893]
  • Eisuke Booka, Chiyo K Imamura, Masashi Takeuchi, Hirofumi Kawakubo, Hiroya Takeuchi, Yusuke Tanigawara, Yuko Kitagawa, Narikazu Boku. Evaluation of clinical validity of an S-1 dosage formula based on renal function using data of the SPIRITS and the G-SOX trials. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. 2022 07; 25(4):770-782. doi: 10.1007/s10120-022-01291-z. [PMID: 35357635]
  • Ankita Tiwari, Devasish Bose, Pooja Mishra, Ankit Jain, Sanjay K Jain. Determination of Oxaliplatin and Curcumin in Combination via Micellar HPLC and Its Method Validation. Journal of AOAC International. 2022 Jun; 105(4):999-1007. doi: 10.1093/jaoacint/qsac042. [PMID: 35353135]
  • Mingzhu Li, Zheng Li, Xiande Ma, Shengbo Jin, Yang Cao, Xuebing Wang, Jian Zhao, Jianbo Wang, Xin Wang, Jian Xu. Huangqi Guizhi Wuwu Decoction can prevent and treat oxaliplatin-induced neuropathic pain by TNFα/IL-1β/IL-6/MAPK/NF-kB pathway. Aging. 2022 Jun; 14(12):5013-5022. doi: 10.18632/aging.203794. [PMID: 35759577]
  • Gunnar Folprecht, Anke Reinacher-Schick, Jürgen Weitz, Celine Lugnier, Anna-Lena Kraeft, Sarah Wisser, Daniela E Aust, Lukas Weiss, Nikolas von Bubnoff, Michael Kramer, Christian Thiede, Andrea Tannapfel. The CIRCULATE Trial: Circulating Tumor DNA Based Decision for Adjuvant Treatment in Colon Cancer Stage II Evaluation (AIO-KRK-0217). Clinical colorectal cancer. 2022 06; 21(2):170-174. doi: 10.1016/j.clcc.2021.09.005. [PMID: 34772609]
  • Rhea Saad, Audra Hannun, Sally Temraz, Antoine Finianos, Rony M Zeenny. Oxaliplatin-induced thrombotic microangiopathy: a case report. Journal of medical case reports. 2022 Mar; 16(1):110. doi: 10.1186/s13256-022-03309-7. [PMID: 35303936]
  • Dou Yang, Feng Chen, Dan Gong, Lei Zeng, Deng Xiang, Yuanqiao He, Leifeng Chen, Jinlong Yan, Shouhua Zhang. Establishment of childhood hepatoblastoma xenografts and evaluation of the anti-tumour effects of anlotinib, oxaliplatin and sorafenib. Pediatric surgery international. 2022 Mar; 38(3):465-472. doi: 10.1007/s00383-021-05043-5. [PMID: 35032209]
  • Marjan Gholami, Azadeh Hekmat, Majid Khazaei, Majid Darroudi. OXA-CuS@UiO-66-NH2 as a drug delivery system for Oxaliplatin to colorectal cancer cells. Journal of materials science. Materials in medicine. 2022 Feb; 33(3):26. doi: 10.1007/s10856-021-06574-y. [PMID: 35226206]
  • Zheng Wang, Yi Li, Rui Mao, Yu Zhang, Jun Wen, Qian Liu, Yanjun Liu, Tongtong Zhang. DNAJB8 in small extracellular vesicles promotes Oxaliplatin resistance through TP53/MDR1 pathway in colon cancer. Cell death & disease. 2022 02; 13(2):151. doi: 10.1038/s41419-022-04599-x. [PMID: 35165262]
  • Wenzhen Yuan, Xingpeng Xiao, Xuan Yu, Fuquan Xie, Pengya Feng, Kamran Malik, Jingyuan Wu, Ze Ye, Peng Zhang, Xiangkai Li. Probiotic Therapy (BIO-THREE) Mitigates Intestinal Microbial Imbalance and Intestinal Damage Caused by Oxaliplatin. Probiotics and antimicrobial proteins. 2022 02; 14(1):60-71. doi: 10.1007/s12602-021-09795-3. [PMID: 33956306]
  • Taro Shibuki, Toshihiko Mizuta, Mototsugu Shimokawa, Futa Koga, Yujiro Ueda, Junichi Nakazawa, Azusa Komori, Satoshi Otsu, Shiho Arima, Masaru Fukahori, Akitaka Makiyama, Hiroki Taguchi, Takuya Honda, Kenji Mitsugi, Kenta Nio, Yasushi Ide, Norio Ureshino, Tsuyoshi Shirakawa, Taiga Otsuka. Prognostic nomogram for patients with unresectable pancreatic cancer treated with gemcitabine plus nab-paclitaxel or FOLFIRINOX: A post-hoc analysis of a multicenter retrospective study in Japan (NAPOLEON study). BMC cancer. 2022 Jan; 22(1):19. doi: 10.1186/s12885-021-09139-y. [PMID: 34980029]
  • Wenen Zhou, Xueying Su, Lusheng Sun, Yanjun Liu, Zhenzhen Wang, Xiaoyu Wang, Yanhong Yang. Efficacy and safety of bevacizumab combined with chemotherapy in the treatment of advanced colorectal cancer and the effect on its adverse reactions. Pakistan journal of pharmaceutical sciences. 2022 Jan; 35(1(Special)):381-386. doi: . [PMID: 35236652]
  • Aerziguli Aierken, Ya-Kai Xie, Wenqi Dong, Abuliken Apaer, Jia-Jia Lin, Zihan Zhao, Shilong Yang, Zhen-Zhong Xu, Fan Yang. Rational Design of a Modality-Specific Inhibitor of TRPM8 Channel against Oxaliplatin-Induced Cold Allodynia. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2021 11; 8(22):e2101717. doi: 10.1002/advs.202101717. [PMID: 34658162]
  • Marion Larroque, Carine Arnaudguilhem, Brice Bouyssiere, François Quenet, Nabila Bouazza, Marta Jarlier, Sonia Boulabas, Sandra Mounicou, Olivia Sgarbura. Evaluation of the environmental contamination and exposure risk in medical/non-medical staff after oxaliplatin-based pressurized intraperitoneal aerosol chemotherapy. Toxicology and applied pharmacology. 2021 10; 429(?):115694. doi: 10.1016/j.taap.2021.115694. [PMID: 34428445]
  • Fleur van der Sijde, Marjolein Y V Homs, Marlies L van Bekkum, Thierry P P van den Bosch, Koop Bosscha, Marc G Besselink, Bert A Bonsing, Jan Willem B de Groot, Thomas M Karsten, Bas Groot Koerkamp, Brigitte C M Haberkorn, Saskia A C Luelmo, Leonie J M Mekenkamp, Dana A M Mustafa, Johanna W Wilmink, Casper H J van Eijck, Eveline E Vietsch, On Behalf Of The Dutch Pancreatic Cancer Group. Serum miR-373-3p and miR-194-5p Are Associated with Early Tumor Progression during FOLFIRINOX Treatment in Pancreatic Cancer Patients: A Prospective Multicenter Study. International journal of molecular sciences. 2021 Oct; 22(20):. doi: 10.3390/ijms222010902. [PMID: 34681562]
  • Atul Batra, Patricia A Tang, Winson Y Cheung. Prognostic Significance of Disease Control at 12 Weeks in Patients With Advanced Pancreatic Cancer Receiving FOLFIRINOX as First-line Chemotherapy. American journal of clinical oncology. 2021 10; 44(10):519-525. doi: 10.1097/coc.0000000000000856. [PMID: 34366400]
  • Ketlyn P da Motta, Briana B Lemos, Jaini J Paltian, Angélica S Dos Reis, Gustavo B Blödorn, Diego Alves, Cristiane Luchese, Ethel A Wilhelm. 7-Chloro-4-(phenylselanyl) quinoline reduces renal oxidative stress induced by oxaliplatin in mice. Canadian journal of physiology and pharmacology. 2021 Oct; 99(10):1102-1111. doi: 10.1139/cjpp-2021-0090. [PMID: 34015230]
  • Hitomi Fujishiro, Hiroki Taguchi, Satoko Hamao, Daigo Sumi, Seiichiro Himeno. Comparisons of segment-specific toxicity of platinum-based agents and cadmium using S1, S2, and S3 cells derived from mouse kidney proximal tubules. Toxicology in vitro : an international journal published in association with BIBRA. 2021 Sep; 75(?):105179. doi: 10.1016/j.tiv.2021.105179. [PMID: 33905841]
  • Stephen N Housley, Travis M Rotterman, Paul Nardelli, Dario I Carrasco, Richard K Noel, Laura O'Farrell, Timothy C Cope. Effects of route of administration on neural exposure to platinum-based chemotherapy treatment: a pharmacokinetic study in rat. Neurotoxicology. 2021 09; 86(?):162-165. doi: 10.1016/j.neuro.2021.08.002. [PMID: 34363843]
  • Tao Ning, Jialu Li, Yi He, Haiyang Zhang, Xinyi Wang, Ting Deng, Rui Liu, Hongli Li, Ming Bai, Qian Fan, Kegan Zhu, Guoguang Ying, Yi Ba. Exosomal miR-208b related with oxaliplatin resistance promotes Treg expansion in colorectal cancer. Molecular therapy : the journal of the American Society of Gene Therapy. 2021 09; 29(9):2723-2736. doi: 10.1016/j.ymthe.2021.04.028. [PMID: 33905821]
  • Nan Zhang, Yafei Hao, Hansheng Liu, Qianqian Yu, Bi Bo, Jianwei Liang. Combined anti-cancer effects of curcumin and oxaliplatin on colon carcinoma colo205 cells using transplanted nude mice. Pakistan journal of pharmaceutical sciences. 2021 Sep; 34(5(Special)):2021-2025. doi: NULL. [PMID: 34862868]
  • R De Luca, C Volpe, O Mistretta, R Paci, G Ferrera, V Caputo, G Rosati, G Cicero. NEPA (netupitant/palonosetron) for the antiemetic prophylaxis of nausea and vomiting induced by chemotherapy (CINV) with Folfirinox and Folfoxiri even during the COVID-19 pandemic: a real-life study. European review for medical and pharmacological sciences. 2021 08; 25(16):5310-5317. doi: 10.26355/eurrev_202108_26552. [PMID: 34486707]
  • Nikhil Biswas, Aiman Abu Ammar, Marina Frušić-Zlotkin, Naama Adi-Hen, Yonat Lehman-Katabi, Yael Levi-Kalisman, Taher Nassar, Simon Benita. Biodistribution and efficacy of the anticancer drug, oxaliplatin palmitate acetate, in mice. International journal of pharmaceutics. 2021 Jul; 604(?):120740. doi: 10.1016/j.ijpharm.2021.120740. [PMID: 34062232]
  • Yaodong Yi, Liping Li, Feifeng Song, Ping Li, Mingyang Chen, Shixin Ni, Hengbin Zhang, Hui Zhou, Su Zeng, Huidi Jiang. L-tetrahydropalmatine reduces oxaliplatin accumulation in the dorsal root ganglion and mitochondria through selectively inhibiting the transporter-mediated uptake thereby attenuates peripheral neurotoxicity. Toxicology. 2021 07; 459(?):152853. doi: 10.1016/j.tox.2021.152853. [PMID: 34252480]
  • Huiya Wang, Xia Wang, Haiyang Zhang, Ting Deng, Rui Liu, Ying Liu, Hongli Li, Ming Bai, Tao Ning, Junyi Wang, Shaohua Ge, Yi Ba. The HSF1/miR-135b-5p axis induces protective autophagy to promote oxaliplatin resistance through the MUL1/ULK1 pathway in colorectal cancer. Oncogene. 2021 07; 40(28):4695-4708. doi: 10.1038/s41388-021-01898-z. [PMID: 34140641]
  • A Taibi, M-L Perrin, J Albouys, J Jacques, C Yardin, S Durand-Fontanier, S M Bardet. 10 ns PEFs induce a histological response linked to cell death and cytotoxic T-lymphocytes in an immunocompetent mouse model of peritoneal metastasis. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. 2021 Jun; 23(6):1220-1237. doi: 10.1007/s12094-020-02525-1. [PMID: 33677709]
  • Yao He, Liuhui Fu, Yiping Li, Wenyan Wang, Mingli Gong, Jing Zhang, Xin Dong, Jiaoyan Huang, Quanbo Wang, Charles R Mackay, Yang-Xin Fu, Yun Chen, Xiaohuan Guo. Gut microbial metabolites facilitate anticancer therapy efficacy by modulating cytotoxic CD8+ T cell immunity. Cell metabolism. 2021 05; 33(5):988-1000.e7. doi: 10.1016/j.cmet.2021.03.002. [PMID: 33761313]
  • Dazhou Xu, Zhimei Zhang, Shuxian Zhang, Xinjian Fang, Lei Wang, Qiuling Li. Efficacy of trastuzumab combined with SOX or IP chemotherapy regimen in the treatment of advanced gastric cancer. Journal of B.U.ON. : official journal of the Balkan Union of Oncology. 2021 May; 26(3):932-939. doi: . [PMID: 34268956]
  • Olivia Jones, Xiaoqian Cheng, Saravana R K Murthy, Lawan Ly, Taisen Zhuang, Giacomo Basadonna, Michael Keidar, Jerome Canady. The synergistic effect of Canady Helios cold atmospheric plasma and a FOLFIRINOX regimen for the treatment of cholangiocarcinoma in vitro. Scientific reports. 2021 04; 11(1):8967. doi: 10.1038/s41598-021-88451-w. [PMID: 33903679]
  • Seth Eisenberg, Kimberly Ito, Angela Rodriguez. Hazardous Drug Contamination: Presence of Bathroom Contamination in an Ambulatory Cancer Center. Clinical journal of oncology nursing. 2021 Apr; 25(2):151-156. doi: 10.1188/21.cjon.151-156. [PMID: 33739338]
  • Briana B Lemos, Ketlyn P da Motta, Jaini J Paltian, Angélica S Reis, Gustavo B Blödorn, Mauro P Soares, Diego Alves, Cristiane Luchese, Ethel A Wilhelm. Role of 7-chloro-4-(phenylselanyl) quinoline in the treatment of oxaliplatin-induced hepatic toxicity in mice. Canadian journal of physiology and pharmacology. 2021 Apr; 99(4):378-388. doi: 10.1139/cjpp-2020-0134. [PMID: 32810410]
  • Young Hoon Choi, Sang Hyub Lee, Min Su You, Bang Sup Shin, Woo Hyun Paik, Ji Kon Ryu, Yong-Tae Kim, Wooil Kwon, Jin-Young Jang, Sun-Whe Kim. Prognostic Factors for Patients with Borderline Resectable or Locally Advanced Pancreatic Cancer Receiving Neoadjuvant FOLFIRINOX. Gut and liver. 2021 Mar; 15(2):315-323. doi: 10.5009/gnl19182. [PMID: 32235008]
  • Mater H Mahnashi, Ashraf M Mahmoud, Khalid Alhazzani, A Z Alanazi, Ali Mohammed Alaseem, Mohammad M Algahtani, Mohamed M El-Wekil. Ultrasensitive and selective molecularly imprinted electrochemical oxaliplatin sensor based on a novel nitrogen-doped carbon nanotubes/Ag@cu MOF as a signal enhancer and reporter nanohybrid. Mikrochimica acta. 2021 03; 188(4):124. doi: 10.1007/s00604-021-04781-6. [PMID: 33712895]
  • Jasmine Giani, Michael B Sawyer, Carole Chambers. Tolerability of pemetrexed and oxaliplatin in the treatment of stage III colon cancer during raltitrexed shortage. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners. 2021 Mar; 27(2):477-479. doi: 10.1177/1078155220934163. [PMID: 32588749]
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  • Ziyuan Wang, Xiaoting Sun, Yuanyuan Feng, Yang Wang, Lu Zhang, Yan Wang, Zhen Fang, Nisma Lena Bahaji Azami, Mingyu Sun, Qi Li. Dihydromyricetin reverses MRP2-induced multidrug resistance by preventing NF-κB-Nrf2 signaling in colorectal cancer cell. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2021 Feb; 82(?):153414. doi: 10.1016/j.phymed.2020.153414. [PMID: 33461143]
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