(+)-Catechin gallate (BioDeep_00000895948)
Main id: BioDeep_00000400547
PANOMIX_OTCML-2023
代谢物信息卡片
(+)-Catechin gallate
化学式: C22H18O10 (442.09)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
InChI: InChI=1S/C22H18O10/c23-11-6-14(25)12-8-19(32-22(30)10-4-16(27)20(29)17(28)5-10)21(31-18(12)7-11)9-1-2-13(24)15(26)3-9/h1-7,19,21,23-29H,8H2/t19-,21+/m0/s1
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:76132
- PubChem: 5276454
- ChEMBL: CHEMBL483083
- CAS: 20819-16-3
- CAS: 25615-05-8
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Ziqiong Zhou, Yan Li, Fangyuan Wang, Guanghao Zhu, Shenglan Qi, Haonan Wang, Yuhe Ma, Rong Zhu, Yuejuan Zheng, Guangbo Ge, Ping Wang. Bioactive components and mechanisms of Pu-erh tea in improving levodopa metabolism in rats through COMT inhibition.
Food & function.
2024 May; 15(10):5287-5299. doi:
10.1039/d4fo00538d. [PMID: 38639730] - Kanane Sato, Shunya Saito, Kohsuke Endo, Masaru Kono, Taishin Kakei, Haruka Taketa, Megumi Kato, Shin Hamamoto, Matteo Grenzi, Alex Costa, Shintaro Munemasa, Yoshiyuki Murata, Yasuhiro Ishimaru, Nobuyuki Uozumi. Green Tea Catechins, (-)-Catechin Gallate, and (-)-Gallocatechin Gallate are Potent Inhibitors of ABA-Induced Stomatal Closure.
Advanced science (Weinheim, Baden-Wurttemberg, Germany).
2022 May; ?(?):e2201403. doi:
10.1002/advs.202201403. [PMID: 35524639] - Xinyue Pang, Shoujing Zhao, Min Zhang, Luning Cai, Yinyin Zhang, Xin Li. Catechin gallate acts as a key metabolite induced by trypsin in Hylocereus undatus during storage indicated by omics.
Plant physiology and biochemistry : PPB.
2021 Jan; 158(?):497-507. doi:
10.1016/j.plaphy.2020.11.036. [PMID: 33257230] - Peter W Taylor. Interactions of Tea-Derived Catechin Gallates with Bacterial Pathogens.
Molecules (Basel, Switzerland).
2020 Apr; 25(8):. doi:
10.3390/molecules25081986. [PMID: 32340372] - Jing Xia, Dan Wang, Pei Liang, De Zhang, Xiaoqing Du, Dejiang Ni, Zhi Yu. Vibrational (FT-IR, Raman) analysis of tea catechins based on both theoretical calculations and experiments.
Biophysical chemistry.
2020 01; 256(?):106282. doi:
10.1016/j.bpc.2019.106282. [PMID: 31756664] - Yinyin Liao, Xiumin Fu, Haiyun Zhou, Wei Rao, Lanting Zeng, Ziyin Yang. Visualized analysis of within-tissue spatial distribution of specialized metabolites in tea (Camellia sinensis) using desorption electrospray ionization imaging mass spectrometry.
Food chemistry.
2019 Sep; 292(?):204-210. doi:
10.1016/j.foodchem.2019.04.055. [PMID: 31054666] - Qing Liu, Guo-Yi Tang, Cai-Ning Zhao, Xiao-Ling Feng, Xiao-Yu Xu, Shi-Yu Cao, Xiao Meng, Sha Li, Ren-You Gan, Hua-Bin Li. Comparison of Antioxidant Activities of Different Grape Varieties.
Molecules (Basel, Switzerland).
2018 Sep; 23(10):. doi:
10.3390/molecules23102432. [PMID: 30249027] - Qunfeng Zhang, Meiya Liu, Jianyun Ruan. Metabolomics analysis reveals the metabolic and functional roles of flavonoids in light-sensitive tea leaves.
BMC plant biology.
2017 03; 17(1):64. doi:
10.1186/s12870-017-1012-8. [PMID: 28320327] - Dong-Mei Fan, Kai Fan, Cui-Ping Yu, Ya-Ting Lu, Xiao-Chang Wang. Tea polyphenols dominate the short-term tea (Camellia sinensis) leaf litter decomposition.
Journal of Zhejiang University. Science. B.
2017 Feb; 18(2):99-108. doi:
10.1631/jzus.b1600044. [PMID: 28124839] - Patrick Müller, Kevin M Downard. Catechin inhibition of influenza neuraminidase and its molecular basis with mass spectrometry.
Journal of pharmaceutical and biomedical analysis.
2015; 111(?):222-30. doi:
10.1016/j.jpba.2015.03.014. [PMID: 25910046] - Marina Naldi, Jessica Fiori, Roberto Gotti, Aurélie Périat, Jean-Luc Veuthey, Davy Guillarme, Vincenza Andrisano. UHPLC determination of catechins for the quality control of green tea.
Journal of pharmaceutical and biomedical analysis.
2014 Jan; 88(?):307-14. doi:
10.1016/j.jpba.2013.08.054. [PMID: 24103292] - Soon Young Shin, Hyuk Yoon, Seunghyun Ahn, Dong-Wook Kim, Sang Ho Kim, Dongsoo Koh, Young Han Lee, Yoongho Lim. Chromenylchalcones showing cytotoxicity on human colon cancer cell lines and in silico docking with aurora kinases.
Bioorganic & medicinal chemistry.
2013 Jul; 21(14):4250-8. doi:
10.1016/j.bmc.2013.04.086. [PMID: 23719279] - Meltem Yilmazer-Musa, Anneke M Griffith, Alexander J Michels, Erik Schneider, Balz Frei. Grape seed and tea extracts and catechin 3-gallates are potent inhibitors of α-amylase and α-glucosidase activity.
Journal of agricultural and food chemistry.
2012 Sep; 60(36):8924-9. doi:
10.1021/jf301147n. [PMID: 22697360] - Yulong Chen, Yueming Jiang, John Shi, Xinlan Xu, Shaoyu Yang, Jun Duan. Effect of girdling at various positions of 'Huang Zhi Xiang' tea tree (Camellia sinensis) on the contents of catechins and starch in fresh leaf.
Plant foods for human nutrition (Dordrecht, Netherlands).
2011 Jun; 66(2):169-74. doi:
10.1007/s11130-011-0222-8. [PMID: 21523413] - Fadi Annaba, Pradeep Kumar, Amish K Dudeja, Seema Saksena, Ravinder K Gill, Waddah A Alrefai. Green tea catechin EGCG inhibits ileal apical sodium bile acid transporter ASBT.
American journal of physiology. Gastrointestinal and liver physiology.
2010 Mar; 298(3):G467-73. doi:
10.1152/ajpgi.00360.2009. [PMID: 20056894] - Kirandeep Kaur, Meenakshi Jain, Tarandeep Kaur, Rahul Jain. Antimalarials from nature.
Bioorganic & medicinal chemistry.
2009 May; 17(9):3229-56. doi:
10.1016/j.bmc.2009.02.050. [PMID: 19299148] - Jin-Kyu Kim, Yeon-Ho Ham, Joseph J Karchesy, Young-Soo Bae. A new phenylpropanoid derivative of catechin from the needles of Taxus cuspidata.
Natural product research.
2008; 22(15):1365-9. doi:
10.1080/14786410701780134. [PMID: 19023796] - Eduardo M Jovel, Xi Ling Zhou, Dong Sheng Ming, Tanya R Wahbe, G H Neil Towers. Bioactivity-guided isolation of the active compounds from Rosa nutkana and quantitative analysis of ascorbic acid by HPLC.
Canadian journal of physiology and pharmacology.
2007 Sep; 85(9):865-71. doi:
10.1139/y07-053. [PMID: 18066132] - H Babich, H L Zuckerbraun, S M Weinerman. In vitro cytotoxicity of (-)-catechin gallate, a minor polyphenol in green tea.
Toxicology letters.
2007 Jul; 171(3):171-80. doi:
10.1016/j.toxlet.2007.05.125. [PMID: 17606338] - Akira Kotani, Kouji Takahashi, Hideki Hakamata, Satoshi Kojima, Fumiyo Kusu. Attomole catechins determination by capillary liquid chromatography with electrochemical detection.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.
2007 Feb; 23(2):157-63. doi:
10.2116/analsci.23.157. [PMID: 17297226] - Rui Zhang, Wenping Xiao, Xuan Wang, Xiaodong Wu, Weixi Tian. Novel inhibitors of fatty-acid synthase from green tea (Camellia sinensis Xihu Longjing) with high activity and a new reacting site.
Biotechnology and applied biochemistry.
2006 Jan; 43(Pt 1):1-7. doi:
10.1042/ba20050064. [PMID: 15943584] - Stéphane Bastianetto, Zhi-Xing Yao, Vassilios Papadopoulos, Rémi Quirion. Neuroprotective effects of green and black teas and their catechin gallate esters against beta-amyloid-induced toxicity.
The European journal of neuroscience.
2006 Jan; 23(1):55-64. doi:
10.1111/j.1460-9568.2005.04532.x. [PMID: 16420415] - Abdelkhaleq Legssyer, Abderrahim Ziyyat, Hassane Mekh, Mohamed Bnouham, Christine Herrenknecht, Vincent Roumy, Christophe Fourneau, Alain Laurens, Jacqueline Hoerter, Rodolphe Fischmeister. Tannins and catechin gallate mediate the vasorelaxant effect of Arbutus unedo on the rat isolated aorta.
Phytotherapy research : PTR.
2004 Nov; 18(11):889-94. doi:
10.1002/ptr.1513. [PMID: 15597331] - Kai On Chu, Chi Chiu Wang, Ching Yan Chu, Michael Scott Rogers, Kwong Wai Choy, Chi Pui Pang. Determination of catechins and catechin gallates in tissues by liquid chromatography with coulometric array detection and selective solid phase extraction.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2004 Oct; 810(2):187-95. doi:
10.1016/j.jchromb.2004.07.031. [PMID: 15380714] - M Okamoto, A Sugimoto, K-P Leung, K Nakayama, A Kamaguchi, N Maeda. Inhibitory effect of green tea catechins on cysteine proteinases in Porphyromonas gingivalis.
Oral microbiology and immunology.
2004 Apr; 19(2):118-20. doi:
10.1046/j.0902-0055.2003.00112.x. [PMID: 14871352] - M R Sartippour, D Heber, J Ma, Q Lu, V L Go, M Nguyen. Green tea and its catechins inhibit breast cancer xenografts.
Nutrition and cancer.
2001; 40(2):149-56. doi:
10.1207/s15327914nc402_11. [PMID: 11962250] - B Yang, K Arai, F Kusu. Determination of catechins in human urine subsequent to tea ingestion by high-performance liquid chromatography with electrochemical detection.
Analytical biochemistry.
2000 Jul; 283(1):77-82. doi:
10.1006/abio.2000.4624. [PMID: 10929811]
