1-O-palmitoyl-2-O-glutaroyl-sn-glycero-3-phosphocholine (BioDeep_00000895614)
代谢物信息卡片
1-O-palmitoyl-2-O-glutaroyl-sn-glycero-3-phosphocholine
化学式: C29H56NO10P (609.3642)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCC(=O)O
InChI: InChI=1S/C29H56NO10P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-20-28(33)37-24-26(40-29(34)21-18-19-27(31)32)25-39-41(35,36)38-23-22-30(2,3)4/h26H,5-25H2,1-4H3,(H-,31,32,35,36)/t26-/m1/s1
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Ahilanandan Dushianthan, Anthony Postle. Methodology to detect oxidised phospholipids and their relevance in disease.
Biochemical Society transactions.
2021 06; 49(3):1241-1250. doi:
10.1042/bst20200852. [PMID: 33960373] - Manuela A A Ayee, Elizabeth LeMaster, Tzu Pin Shentu, Dev K Singh, Nicolas Barbera, Dheeraj Soni, Chinnaswamy Tiruppathi, Papasani V Subbaiah, Evgeny Berdyshev, Irina Bronova, Michael Cho, Belinda S Akpa, Irena Levitan. Molecular-Scale Biophysical Modulation of an Endothelial Membrane by Oxidized Phospholipids.
Biophysical journal.
2017 Jan; 112(2):325-338. doi:
10.1016/j.bpj.2016.12.002. [PMID: 28122218] - F Vogl, J Humpolícková, M Amaro, D Koller, H Köfeler, E Zenzmaier, M Hof, A Hermetter. Role of protein kinase C δ in apoptotic signaling of oxidized phospholipids in RAW 264.7 macrophages.
Biochimica et biophysica acta.
2016 Apr; 1861(4):320-30. doi:
10.1016/j.bbalip.2015.12.009. [PMID: 26707247] - Mario Brameshuber, Eva Sevcsik, Benedikt K Rossboth, Christina Manner, Hans-Peter Deigner, Begüm Peksel, Mária Péter, Zsolt Török, Albin Hermetter, Gerhard J Schütz. Oxidized Phospholipids Inhibit the Formation of Cholesterol-Dependent Plasma Membrane Nanoplatforms.
Biophysical journal.
2016 Jan; 110(1):205-13. doi:
10.1016/j.bpj.2015.11.018. [PMID: 26745423] - Claudia Ramprecht, Hannah Jaritz, Ingo Streith, Elfriede Zenzmaier, Harald Köfeler, Rainer Hofmann-Wellenhof, Helmut Schaider, Albin Hermetter. Toxicity of oxidized phosphatidylcholines in cultured human melanoma cells.
Chemistry and physics of lipids.
2015 Jul; 189(?):39-47. doi:
10.1016/j.chemphyslip.2015.05.007. [PMID: 26028612] - Jasmeet Singh, Radha Ranganathan. Mixing of oxidized and bilayer phospholipids.
Biochimica et biophysica acta.
2015 Jul; 1848(7):1472-80. doi:
10.1016/j.bbamem.2015.03.027. [PMID: 25839354] - Giovanni Vinetti, Chiara Mozzini, Paolo Desenzani, Enrico Boni, Laura Bulla, Isabella Lorenzetti, Claudia Romano, Andrea Pasini, Luciano Cominacini, Deodato Assanelli. Supervised exercise training reduces oxidative stress and cardiometabolic risk in adults with type 2 diabetes: a randomized controlled trial.
Scientific reports.
2015 Mar; 5(?):9238. doi:
10.1038/srep09238. [PMID: 25783765] - Qun Li, Yuantong Tian, Dandi Li, Jianfeng Sun, Donglei Shi, Lin Fang, Yong Gao, Haiyan Liu. The effect of lipocisplatin on cisplatin efficacy and nephrotoxicity in malignant breast cancer treatment.
Biomaterials.
2014 Aug; 35(24):6462-72. doi:
10.1016/j.biomaterials.2014.04.023. [PMID: 24797881] - Lingaraju M Halasiddappa, Harald Koefeler, Anthony H Futerman, Albin Hermetter. Oxidized phospholipids induce ceramide accumulation in RAW 264.7 macrophages: role of ceramide synthases.
PloS one.
2013; 8(7):e70002. doi:
10.1371/journal.pone.0070002. [PMID: 23936132] - U Stemmer, C Ramprecht, E Zenzmaier, B Stojčić, G Rechberger, M Kollroser, A Hermetter. Uptake and protein targeting of fluorescent oxidized phospholipids in cultured RAW 264.7 macrophages.
Biochimica et biophysica acta.
2012 Apr; 1821(4):706-18. doi:
10.1016/j.bbalip.2012.01.014. [PMID: 22333180] - Eman Al-Shawaf, Jacqueline Naylor, Hilary Taylor, Kirsten Riches, Carol J Milligan, David O'Regan, Karen E Porter, Jing Li, David J Beech. Short-term stimulation of calcium-permeable transient receptor potential canonical 5-containing channels by oxidized phospholipids.
Arteriosclerosis, thrombosis, and vascular biology.
2010 Jul; 30(7):1453-9. doi:
10.1161/atvbaha.110.205666. [PMID: 20378846] - Raquel F Epand, Vinod K Mishra, Mayakonda N Palgunachari, G M Anantharamaiah, Richard M Epand. Anti-inflammatory peptides grab on to the whiskers of atherogenic oxidized lipids.
Biochimica et biophysica acta.
2009 Sep; 1788(9):1967-75. doi:
10.1016/j.bbamem.2009.06.015. [PMID: 19559666] - Alexandra Moumtzi, Michael Trenker, Karlheinz Flicker, Elfriede Zenzmaier, Robert Saf, Albin Hermetter. Import and fate of fluorescent analogs of oxidized phospholipids in vascular smooth muscle cells.
Journal of lipid research.
2007 Mar; 48(3):565-82. doi:
10.1194/jlr.m600394-jlr200. [PMID: 17135656] - Gilbert O Fruhwirth, Alexandra Moumtzi, Alexandra Loidl, Elisabeth Ingolic, Albin Hermetter. The oxidized phospholipids POVPC and PGPC inhibit growth and induce apoptosis in vascular smooth muscle cells.
Biochimica et biophysica acta.
2006 Sep; 1761(9):1060-9. doi:
10.1016/j.bbalip.2006.06.001. [PMID: 16904371] - Jennifer L Kanter, Sirisha Narayana, Peggy P Ho, Ingrid Catz, Kenneth G Warren, Raymond A Sobel, Lawrence Steinman, William H Robinson. Lipid microarrays identify key mediators of autoimmune brain inflammation.
Nature medicine.
2006 Jan; 12(1):138-43. doi:
10.1038/nm1344. [PMID: 16341241]
