2-Amino-5-hydroxy-1-methylimidazol-4(5H)-one (BioDeep_00000894738)
代谢物信息卡片
2-Amino-5-hydroxy-1-methylimidazol-4(5H)-one
化学式: C4H7N3O2 (129.0538242)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN1C(C(=O)NC1=N)O
InChI: InChI=1S/C4H7N3O2/c1-7-3(9)2(8)6-4(7)5/h3,9H,1H3,(H2,5,6,8)
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Kazuharu Ienaga, Chan Hum Park, Takako Yokozawa. Daily hydroxyl radical scavenging capacity of mammals.
Drug discoveries & therapeutics.
2014 Apr; 8(2):71-5. doi:
10.5582/ddt.8.71. [PMID: 24815581] - Kazuharu Ienaga, Ko Nakamura, Tomoe Fujisawa, Yasutsugu Fukunaga, Hiroshi Nihei, Mitsuharu Narita, Yasuhiko Tomino, Tsutomu Sanaka, Kazumasa Aoyagi, Koji Nakano, Hikaru Koide. Urinary excretion of creatol, an in vivo biomarker of hydroxyl radical, in patients with chronic renal failure.
Renal failure.
2007; 29(3):279-83. doi:
10.1080/08860220701219863. [PMID: 17497440] - S Matsumoto, T Hanai, T Matsuura, H Uemura, T Nishioka, T Akiyama. Creatol, an oxidative product of creatinine in kidney transplant patients, as a useful determinant of renal function: a preliminary study.
Transplantation proceedings.
2006 Sep; 38(7):2009-11. doi:
10.1016/j.transproceed.2006.06.104. [PMID: 16979981] - Motoo Osaka, Kazumasa Aoyagi, Akiko Hirakawa, Motoo Nakajima, Tomoaki Jikuya, Osamu Shigeta, Yuzuru Sakakibara. Comparison of hydroxyl radical generation in patients undergoing coronary artery bypass grafting with and without cardiopulmonary bypass.
Free radical research.
2006 Feb; 40(2):127-33. doi:
10.1080/10715760500428705. [PMID: 16390821] - Krista B Halling, Gary W Ellison, Don Armstrong, Kasumi Aoyagi, Carol J Detrisac, John P Graham, Susan P Newell, Frank G Martin, James M Van Gilder. Evaluation of oxidative stress markers for the early diagnosis of allograft rejection in feline renal allotransplant recipients with normal renal function.
The Canadian veterinary journal = La revue veterinaire canadienne.
2004 Oct; 45(10):831-7. doi:
NULL. [PMID: 15532882] - C Tomida, K Aoyagi, S Nagase, M Gotoh, K Yamagata, K Takemura, A Koyama. Creatol, an oxidative product of creatinine in hemodialysis patients.
Free radical research.
2000 Jan; 32(1):85-92. doi:
10.1080/10715760000300091. [PMID: 10625220] - H Ozasa, T Watanabe, K Nakamura, Y Fukunaga, K Ienaga, K Hagiwara. Changes in serum levels of creatol and methylguanidine in renal injury induced by lipid peroxide produced by vitamin E deficiency and GSH depletion in rats.
Nephron.
1997; 75(2):224-9. doi:
10.1159/000189536. [PMID: 9041546] - T Yokozawa, N Fujitsuka, H Oura, K Ienaga, K Nakamura. In vivo effect of hydroxyl radical scavenger on methylguanidine production from creatinine.
Nephron.
1997; 75(1):103-5. doi:
10.1159/000189510. [PMID: 9031281] - K Nakamura, K Ienaga, K Nakano, M Nakai, Y Nakamura, G Hasegawa, M Sawada, M Kondo, H Mori, T Kanatsuna. Diabetic renal failure and serum accumulation of the creatinine oxidative metabolites creatol and methylguanidine.
Nephron.
1996; 73(4):520-5. doi:
10.1159/000189134. [PMID: 8856245] - K Ienaga, K Nakamura, Y Fukunaga, K Nakano, T Kanatsuna. Creatol and chronic renal failure.
Kidney international. Supplement.
1994 Nov; 47(?):S22-4. doi:
NULL. [PMID: 7869666] - K Nakamura, K Ienaga, K Nakano, M Nakai, Y Nakamura, G Hasegawa, M Sawada, M Kondo, H Mori, T Kanatsuna. Creatol, a creatinine metabolite, as a useful determinant of renal function.
Nephron.
1994; 66(2):140-6. doi:
10.1159/000187791. [PMID: 8139732] - T Yokozawa, H Oura, K Ienaga, K Nakamura. Comparison of renal effects of creatinine, creatol and methylguanidine in rats with adenine-induced chronic renal failure.
Nephron.
1993; 64(3):424-8. doi:
10.1159/000187365. [PMID: 8341388] - T Yokozawa, N Fujitsuka, H Oura, T Akao, K Kobashi, K Ienaga, K Nakamura, M Hattori. Purification of methylguanidine synthase from the rat kidney.
Nephron.
1993; 63(4):452-7. doi:
10.1159/000187251. [PMID: 8459882] - T Yokozawa, H Oura, K Ienaga, K Nakamura. Effects of creatinine, creatol and methylguanidine on renal function.
Nihon Jinzo Gakkai shi.
1992 Sep; 34(9):973-7. doi:
NULL. [PMID: 1479734] - K Nakamura, K Ienaga, T Yokozawa, N Fujitsuka, H Oura. Production of methylguanidine from creatinine via creatol by active oxygen species: analyses of the catabolism in vitro.
Nephron.
1991; 58(1):42-6. doi:
10.1159/000186376. [PMID: 1649975] - K Nakamura, K Ienaga. Creatol (5-hydroxycreatinine), a new toxin candidate in uremic patients.
Experientia.
1990 May; 46(5):470-2. doi:
10.1007/bf01954234. [PMID: 2347396]