8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol (BioDeep_00000893824)
代谢物信息卡片
化学式: C17H18BrNO (331.0571678)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)Br
InChI: InChI=1S/C17H18BrNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3
描述信息
D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists
D004791 - Enzyme Inhibitors > D000067956 - Adenylyl Cyclase Inhibitors
同义名列表
相关代谢途径
Reactome(0)
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PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Katsura Takano, Nobuyuki Tanaka, Kenji Kawabe, Mitsuaki Moriyama, Yoichi Nakamura. Extracellular superoxide dismutase induced by dopamine in cultured astrocytes.
Neurochemical research.
2013 Jan; 38(1):32-41. doi:
10.1007/s11064-012-0882-2. [PMID: 22983620] - Melissa A Stouffer, Solav Ali, Maarten E A Reith, Jyoti C Patel, Federica Sarti, Kenneth D Carr, Margaret E Rice. SKF-83566, a D1-dopamine receptor antagonist, inhibits the dopamine transporter.
Journal of neurochemistry.
2011 Sep; 118(5):714-20. doi:
10.1111/j.1471-4159.2011.07357.x. [PMID: 21689106] - Rui Pedrosa, Pedro Gomes, Chunyu Zeng, Ulrich Hopfer, Pedro A Jose, Patrício Soares-da-Silva. Dopamine D3 receptor-mediated inhibition of Na+/H+ exchanger activity in normotensive and spontaneously hypertensive rat proximal tubular epithelial cells.
British journal of pharmacology.
2004 Aug; 142(8):1343-53. doi:
10.1038/sj.bjp.0705893. [PMID: 15265811] - Pedro Gomes, P Soares-Da-Silva. D2-like receptor-mediated inhibition of Na+-K+-ATPase activity is dependent on the opening of K+ channels.
American journal of physiology. Renal physiology.
2002 Jul; 283(1):F114-23. doi:
10.1152/ajprenal.00244.2001. [PMID: 12060593] - P Gomes, M A Vieira-Coelho, P Soares-Da-Silva. Ouabain-insensitive acidification by dopamine in renal OK cells: primary control of the Na(+)/H(+) exchanger.
American journal of physiology. Regulatory, integrative and comparative physiology.
2001 Jul; 281(1):R10-8. doi:
10.1152/ajpregu.2001.281.1.r10. [PMID: 11404273] - V A Lucas-Teixeira, M A Vieira-Coelho, P Serrão, M Pestana, P Soares-da-Silva. Salt intake and sensitivity of intestinal and renal Na+-K+ atpase to inhibition by dopamine in spontaneous hypertensive and Wistar-Kyoto rats.
Clinical and experimental hypertension (New York, N.Y. : 1993).
2000 Jul; 22(5):455-69. doi:
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The Journal of laboratory and clinical medicine.
1998 Oct; 132(4):308-12. doi:
10.1016/s0022-2143(98)90044-0. [PMID: 9794702] - J S Noh, B J Gwag. Attenuation of oxidative neuronal necrosis by a dopamine D1 agonist in mouse cortical cell cultures.
Experimental neurology.
1997 Aug; 146(2):604-8. doi:
10.1006/exnr.1997.6569. [PMID: 9270075] - N Sunn, O L Woodman, C Bell. Involvement of dopamine in control of renal blood flow.
Journal of the autonomic nervous system.
1992 Nov; 41(1-2):113-20. doi:
10.1016/0165-1838(92)90133-2. [PMID: 1491107] - A O Wong, J P Chang, R E Peter. Dopamine stimulates growth hormone release from the pituitary of goldfish, Carassius auratus, through the dopamine D1 receptors.
Endocrinology.
1992 Mar; 130(3):1201-10. doi:
10.1210/endo.130.3.1347006. [PMID: 1347006] - B D Sloley, V L Trudeau, J G Dulka, R E Peter. Selective depletion of dopamine in the goldfish pituitary caused by domperidone.
Canadian journal of physiology and pharmacology.
1991 Jun; 69(6):776-81. doi:
10.1139/y91-116. [PMID: 1680540] - R K Sunahara, H C Guan, B F O'Dowd, P Seeman, L G Laurier, G Ng, S R George, J Torchia, H H Van Tol, H B Niznik. Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1.
Nature.
1991 Apr; 350(6319):614-9. doi:
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