4-hydroxy-1-(pyrrolidine-2-carbonyl)pyrrolidine-2-carboxylic acid (BioDeep_00000893806)
代谢物信息卡片
化学式: C10H16N2O4 (228.111)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CC(NC1)C(=O)N2CC(CC2C(=O)O)O
InChI: InChI=1S/C10H16N2O4/c13-6-4-8(10(15)16)12(5-6)9(14)7-2-1-3-11-7/h6-8,11,13H,1-5H2,(H,15,16)
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Tomoko T Asai, Fumi Oikawa, Kazunobu Yoshikawa, Naoki Inoue, Kenji Sato. Food-Derived Collagen Peptides, Prolyl-Hydroxyproline (Pro-Hyp), and Hydroxyprolyl-Glycine (Hyp-Gly) Enhance Growth of Primary Cultured Mouse Skin Fibroblast Using Fetal Bovine Serum Free from Hydroxyprolyl Peptide.
International journal of molecular sciences.
2019 Dec; 21(1):. doi:
10.3390/ijms21010229. [PMID: 31905705] - Yasutaka Shigemura, Yu Iwasaki, Mana Tateno, Asahi Suzuki, Mihoko Kurokawa, Yoshio Sato, Kenji Sato. A Pilot Study for the Detection of Cyclic Prolyl-Hydroxyproline (Pro-Hyp) in Human Blood after Ingestion of Collagen Hydrolysate.
Nutrients.
2018 Sep; 10(10):. doi:
10.3390/nu10101356. [PMID: 30248982] - Jun A Minaguchi, Sakino Ogata, Naoki Takahashi, Takuya Hirose, Hiromi Ueda, Kazushige Takehana. Remodeling of rat stromal-vascular cells to brite/beige adipocytes by prolyl-hydroxyproline.
The Journal of veterinary medical science.
2017 Mar; 79(3):547-553. doi:
10.1292/jvms.16-0163. [PMID: 28123139] - Misato Yazaki, Yukihiko Ito, Masayoshi Yamada, Spyros Goulas, Sachiyuki Teramoto, Masa-Aki Nakaya, Shigeo Ohno, Kohji Yamaguchi. Oral Ingestion of Collagen Hydrolysate Leads to the Transportation of Highly Concentrated Gly-Pro-Hyp and Its Hydrolyzed Form of Pro-Hyp into the Bloodstream and Skin.
Journal of agricultural and food chemistry.
2017 Mar; 65(11):2315-2322. doi:
10.1021/acs.jafc.6b05679. [PMID: 28244315] - Hee-Jung Sim, Eunjung Moon, Sun Yeou Kim, Seon-Pyo Hong. Determination of proline-hydroxyproline dipeptide in rat urine by high-performance anion-exchange chromatography coupled with pulsed amperometric detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2013 Jul; 930(?):70-4. doi:
10.1016/j.jchromb.2013.04.033. [PMID: 23727869] - Jana Cimlová, Pavla Kružberská, Zdeněk Švagera, Petr Hušek, Petr Šimek. In situ derivatization-liquid liquid extraction as a sample preparation strategy for the determination of urinary biomarker prolyl-4-hydroxyproline by liquid chromatography-tandem mass spectrometry.
Journal of mass spectrometry : JMS.
2012 Mar; 47(3):294-302. doi:
10.1002/jms.2952. [PMID: 22431455] - Fumihito Sugihara, Naoki Inoue, Masanori Kuwamori, Makoto Taniguchi. Quantification of hydroxyprolyl-glycine (Hyp-Gly) in human blood after ingestion of collagen hydrolysate.
Journal of bioscience and bioengineering.
2012 Feb; 113(2):202-3. doi:
10.1016/j.jbiosc.2011.09.024. [PMID: 22040651] - Tomoaki Kawaguchi, Patricia Naomi Nanbu, Mihoko Kurokawa. Distribution of prolylhydroxyproline and its metabolites after oral administration in rats.
Biological & pharmaceutical bulletin.
2012; 35(3):422-7. doi:
10.1248/bpb.35.422. [PMID: 22382331] - Petr Husek, Zdenek Svagera, Frantisek Vsianský, Janka Franeková, Petr Simek. Prolyl-hydroxyproline dipeptide in non-hydrolyzed morning urine and its value in postmenopausal osteoporosis.
Clinical chemistry and laboratory medicine.
2008; 46(10):1391-7. doi:
10.1515/cclm.2008.259. [PMID: 18844493]
