Phosphatidyl-L-serine (BioDeep_00000869380)
代谢物信息卡片
(2S)-2-amino-3-[hydroxy-[(2R)-2-(1-oxobutoxy)-3-(1-oxopropoxy)propoxy]phosphoryl]oxypropanoic acid
化学式: C13H24NO10P (385.1137774)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCC(=O)OC(COC(=O)CC)COP(=O)(O)OCC(C(=O)O)N
InChI: InChI=1S/C13H24NO10P/c1-3-5-12(16)24-9(6-21-11(15)4-2)7-22-25(19,20)23-8-10(14)13(17)18/h9-10H,3-8,14H2,1-2H3,(H,17,18)(H,19,20)/t9-,10+/m1/s1
描述信息
同义名列表
8 个代谢物同义名
(2S)-2-amino-3-[hydroxy-[(2R)-2-(1-oxobutoxy)-3-(1-oxopropoxy)propoxy]phosphoryl]oxypropanoic acid; (2S)-2-amino-3-[[(2R)-2-butanoyloxy-3-propanoyloxy-propoxy]-hydroxy-phosphoryl]oxy-propanoic acid; (2S)-2-amino-3-[[(2R)-2-butyryloxy-3-propionyloxy-propoxy]-hydroxy-phosphoryl]oxy-propionic acid; (2S)-2-amino-3-[[(2R)-2-butanoyloxy-3-propanoyloxypropoxy]-hydroxyphosphoryl]oxypropanoic acid; 1,2-Diacyl-sn-glycerol 3-phospho-L-serine; 3-O-sn-Phosphatidyl-L-serine; O3-Phosphatidyl-L-serine; Phosphatidyl-L-serine
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 33090 - 西洋参: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Sonja Grunewald, Uwe Paasch. Sperm selection for ICSI using annexin V.
Methods in molecular biology (Clifton, N.J.).
2013; 927(?):257-62. doi:
10.1007/978-1-62703-038-0_23. [PMID: 22992920] - Anna K Larsen, Arnaldur Hall, Henrik Lundsgart, S Moein Moghimi. Combined fluorimetric caspase 3/7 assay and bradford protein determination for assessment of polycation-mediated cytotoxicity.
Methods in molecular biology (Clifton, N.J.).
2013; 948(?):23-33. doi:
10.1007/978-1-62703-140-0_3. [PMID: 23070761] - Rob van Zwieten, Andrea E Bochem, Petra M Hilarius, Robin van Bruggen, Ferry Bergkamp, G Kees Hovingh, Arthur J Verhoeven. The cholesterol content of the erythrocyte membrane is an important determinant of phosphatidylserine exposure.
Biochimica et biophysica acta.
2012 Dec; 1821(12):1493-500. doi:
10.1016/j.bbalip.2012.08.008. [PMID: 22960544] - Olga A Koval, Alexandr S Fomin, Vasily I Kaledin, Dmitry V Semenov, Miraslava O Potapenko, Elena V Kuligina, Valery P Nikolin, Eugeny V Nikitenko, Vladimir A Richter. A novel pro-apoptotic effector lactaptin inhibits tumor growth in mice models.
Biochimie.
2012 Dec; 94(12):2467-74. doi:
10.1016/j.biochi.2012.08.017. [PMID: 22968174] - Hongxia Li, Pan Wang, Quanhong Liu, Xiaoxia Cheng, Yuetao Zhou, Yaping Xiao. Cell cycle arrest and cell apoptosis induced by Equisetum hyemale extract in murine leukemia L1210 cells.
Journal of ethnopharmacology.
2012 Nov; 144(2):322-7. doi:
10.1016/j.jep.2012.09.015. [PMID: 23000169] - Elisabetta Straface, Alessandra Marchesi, Lucrezia Gambardella, Alessio Metere, Isabella Tarissi de Jacobis, Marina Viora, Luciana Giordani, Alberto Villani, Domenico Del Principe, Walter Malorni, Donatella Pietraforte. Does oxidative stress play a critical role in cardiovascular complications of Kawasaki disease?.
Antioxidants & redox signaling.
2012 Nov; 17(10):1441-6. doi:
10.1089/ars.2012.4660. [PMID: 22578402] - Brent Rogaski, Jeffery B Klauda. Membrane-binding mechanism of a peripheral membrane protein through microsecond molecular dynamics simulations.
Journal of molecular biology.
2012 Nov; 423(5):847-61. doi:
10.1016/j.jmb.2012.08.015. [PMID: 22925581] - Matthew F Whelihan, Vicentios Zachary, Thomas Orfeo, Kenneth G Mann. Prothrombin activation in blood coagulation: the erythrocyte contribution to thrombin generation.
Blood.
2012 Nov; 120(18):3837-45. doi:
10.1182/blood-2012-05-427856. [PMID: 22968460] - Françoise Illien, Hong-Rong Piao, Marine Coué, Chiara di Marco, Jesus Ayala-Sanmartin. Lipid organization regulates annexin A2 Ca(2+)-sensitivity for membrane bridging and its modulator effects on membrane fluidity.
Biochimica et biophysica acta.
2012 Nov; 1818(11):2892-900. doi:
10.1016/j.bbamem.2012.07.012. [PMID: 22842545] - Gavin W Sewell, Yusuf A Hannun, Xianlin Han, Grielof Koster, Jacek Bielawski, Victoria Goss, Philip J Smith, Farooq Z Rahman, Roser Vega, Stuart L Bloom, Ann P Walker, Anthony D Postle, Anthony W Segal. Lipidomic profiling in Crohn's disease: abnormalities in phosphatidylinositols, with preservation of ceramide, phosphatidylcholine and phosphatidylserine composition.
The international journal of biochemistry & cell biology.
2012 Nov; 44(11):1839-46. doi:
10.1016/j.biocel.2012.06.016. [PMID: 22728312] - Jaeyong Cho, In-sok Hwang, Hyemin Choi, Ji Hong Hwang, Jae-Sam Hwang, Dong Gun Lee. The novel biological action of antimicrobial peptides via apoptosis induction.
Journal of microbiology and biotechnology.
2012 Nov; 22(11):1457-66. doi:
10.4014/jmb.1205.05041. [PMID: 23124334] - Marie-Claire Kleinegris, Ger H Koek, Kelly Mast, Eveline H C Mestrom, Jef L N Wolfs, Edouard M Bevers. Ribavirin-induced externalization of phosphatidylserine in erythrocytes is predominantly caused by inhibition of aminophospholipid translocase activity.
European journal of pharmacology.
2012 Oct; 693(1-3):1-6. doi:
10.1016/j.ejphar.2012.07.041. [PMID: 22959357] - James J Asciolla, Thibaud T Renault, Jerry E Chipuk. Examining BCL-2 family function with large unilamellar vesicles.
Journal of visualized experiments : JoVE.
2012 Oct; ?(68):. doi:
10.3791/4291. [PMID: 23070252] - N J Mutch, E K Waters, J H Morrissey. Immobilized transition metal ions stimulate contact activation and drive factor XII-mediated coagulation.
Journal of thrombosis and haemostasis : JTH.
2012 Oct; 10(10):2108-15. doi:
10.1111/j.1538-7836.2012.04890.x. [PMID: 22905925] - Sussan K Ardestani, Fatemeh Poorrajab, Sepideh Razmi, Alireza Foroumadi, Soheila Ajdary, Behnaz Gharegozlou, Mina Behrouzi-Fardmoghadam, Abbas Shafiee. Cell death features induced in Leishmania major by 1,3,4-thiadiazole derivatives.
Experimental parasitology.
2012 Oct; 132(2):116-22. doi:
10.1016/j.exppara.2012.06.002. [PMID: 22959410] - Ryohei Hamaguchi, Yukihiro Kuroda, Toshiko Tanimoto, Jun Haginaka. Role of bis(monoacylglycero)phosphate in propranolol binding to phospholipid membranes under acidic conditions as measured by high-performance frontal analysis/capillary electrophoresis.
Electrophoresis.
2012 Oct; 33(19-20):3101-6. doi:
10.1002/elps.201200324. [PMID: 22996699] - Pamela Ovadje, Madona Chochkeh, Pardis Akbari-Asl, Caroline Hamm, Siyaram Pandey. Selective induction of apoptosis and autophagy through treatment with dandelion root extract in human pancreatic cancer cells.
Pancreas.
2012 Oct; 41(7):1039-47. doi:
10.1097/mpa.0b013e31824b22a2. [PMID: 22647733] - Zachary A Levine, P Thomas Vernier. Calcium and phosphatidylserine inhibit lipid electropore formation and reduce pore lifetime.
The Journal of membrane biology.
2012 Oct; 245(10):599-610. doi:
10.1007/s00232-012-9471-1. [PMID: 22815071] - Rima Chattopadhyay, Tanusree Sengupta, Rinku Majumder. Inhibition of intrinsic Xase by protein S: a novel regulatory role of protein S independent of activated protein C.
Arteriosclerosis, thrombosis, and vascular biology.
2012 Oct; 32(10):2387-93. doi:
10.1161/atvbaha.112.250928. [PMID: 22904276] - Paola E J van der Meijden, Marion A H Feijge, Frauke Swieringa, Karen Gilio, Reyhan Nergiz-Unal, Karly Hamulyák, Johan W M Heemskerk. Key role of integrin α(IIb)β (3) signaling to Syk kinase in tissue factor-induced thrombin generation.
Cellular and molecular life sciences : CMLS.
2012 Oct; 69(20):3481-92. doi:
10.1007/s00018-012-1033-2. [PMID: 22669259] - A P Demchenko. The change of cellular membranes on apoptosis: fluorescence detection.
Experimental oncology.
2012 Oct; 34(3):263-8. doi:
NULL. [PMID: 23070011] - Samantha Reid, Lacey Johnson, Narelle Woodland, Denese C Marks. Pathogen reduction treatment of buffy coat platelet concentrates in additive solution induces proapoptotic signaling.
Transfusion.
2012 Oct; 52(10):2094-103. doi:
10.1111/j.1537-2995.2011.03558.x. [PMID: 22320126] - Qing Shen, Youyi Wang, Like Gong, Rui Guo, Wei Dong, Hon-Yeung Cheung. Shotgun lipidomics strategy for fast analysis of phospholipids in fisheries waste and its potential in species differentiation.
Journal of agricultural and food chemistry.
2012 Sep; 60(37):9384-93. doi:
10.1021/jf303181s. [PMID: 22946708] - Rama Pichika, Ameer Y Taha, Fei Gao, Kishore Kotta, Yewon Cheon, Lisa Chang, Dale Kiesewetter, Stanley I Rapoport, William C Eckelman. The synthesis and in vivo pharmacokinetics of fluorinated arachidonic acid: implications for imaging neuroinflammation.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2012 Sep; 53(9):1383-91. doi:
10.2967/jnumed.112.105734. [PMID: 22851635] - Georg Künze, Patrick Barré, Holger A Scheidt, Lars Thomas, David Eliezer, Daniel Huster. Binding of the three-repeat domain of tau to phospholipid membranes induces an aggregated-like state of the protein.
Biochimica et biophysica acta.
2012 Sep; 1818(9):2302-13. doi:
10.1016/j.bbamem.2012.03.019. [PMID: 22521809] - Katarzyna Hąc-Wydro, Patrycja Dynarowicz-Łątka. Externalization of phosphatidylserine from inner to outer layer may alter the effect of plant sterols on human erythrocyte membrane - the Langmuir monolayer studies.
Biochimica et biophysica acta.
2012 Sep; 1818(9):2184-91. doi:
10.1016/j.bbamem.2012.05.010. [PMID: 22613189] - Julie Gabillet, Arnaud Millet, Magali Pederzoli-Ribeil, Pascale Tacnet-Delorme, Loïc Guillevin, Luc Mouthon, Philippe Frachet, Véronique Witko-Sarsat. Proteinase 3, the autoantigen in granulomatosis with polyangiitis, associates with calreticulin on apoptotic neutrophils, impairs macrophage phagocytosis, and promotes inflammation.
Journal of immunology (Baltimore, Md. : 1950).
2012 Sep; 189(5):2574-83. doi:
10.4049/jimmunol.1200600. [PMID: 22844112] - Marit Hellum, Reidun Øvstebø, Anne-Marie S Trøseid, Jens P Berg, Petter Brandtzaeg, Carola E Henriksson. Microparticle-associated tissue factor activity measured with the Zymuphen MP-TF kit and the calibrated automated thrombogram assay.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.
2012 Sep; 23(6):520-6. doi:
10.1097/mbc.0b013e328354a256. [PMID: 22732249] - Nivaldo R de Moura, Maria F Cury-Boaventura, Vinicius C Santos, Adriana C Levada-Pires, Joséricardo Bortolon, Jarlei Fiamoncini, Tania C Pithon-Curi, Rui Curi, Elaine Hatanaka. Inflammatory response and neutrophil functions in players after a futsal match.
Journal of strength and conditioning research.
2012 Sep; 26(9):2507-14. doi:
10.1519/jsc.0b013e31823f29b5. [PMID: 22067240] - Jiuxin Zhu, Rui Xie, Xianmei Piao, Yunlong Hou, Chongbao Zhao, Guofen Qiao, Baofeng Yang, Jialan Shi, Yanjie Lu. Homocysteine enhances clot-promoting activity of endothelial cells via phosphatidylserine externalization and microparticles formation.
Amino acids.
2012 Sep; 43(3):1243-50. doi:
10.1007/s00726-011-1196-4. [PMID: 22160264] - Karol Kramkowski, Agnieszka Leszczynska, Andrzej Mogielnicki, Stefan Chlopicki, Andrzej Fedorowicz, Elzbieta Grochal, Brian Mann, Tomasz Brzoska, Tetsumei Urano, Roberto Motterlini, Wlodzimierz Buczko. Antithrombotic properties of water-soluble carbon monoxide-releasing molecules.
Arteriosclerosis, thrombosis, and vascular biology.
2012 Sep; 32(9):2149-57. doi:
10.1161/atvbaha.112.253989. [PMID: 22772756] - Zachary T Graber, Zhiping Jiang, Arne Gericke, Edgar E Kooijman. Phosphatidylinositol-4,5-bisphosphate ionization and domain formation in the presence of lipids with hydrogen bond donor capabilities.
Chemistry and physics of lipids.
2012 Sep; 165(6):696-704. doi:
10.1016/j.chemphyslip.2012.07.003. [PMID: 22820347] - Xiaoxia Cheng, Yaping Xiao, Xiaobing Wang, Pan Wang, Hongxia Li, Han Yan, Quanhong Liu. Anti-tumor and pro-apoptotic activity of ethanolic extract and its various fractions from Polytrichum commune L.ex Hedw in L1210 cells.
Journal of ethnopharmacology.
2012 Aug; 143(1):49-56. doi:
10.1016/j.jep.2012.05.054. [PMID: 22687253] - Catherine B Dieck, Austin Wood, Irena Brglez, Marcela Rojas-Pierce, Wendy F Boss. Increasing phosphatidylinositol (4,5) bisphosphate biosynthesis affects plant nuclear lipids and nuclear functions.
Plant physiology and biochemistry : PPB.
2012 Aug; 57(?):32-44. doi:
10.1016/j.plaphy.2012.05.011. [PMID: 22677448] - Silvia Montoro-García, Eduard Shantsila, Esteban Orenes-Piñero, María Luisa Lozano, Gregory Y H Lip. An innovative flow cytometric approach for small-size platelet microparticles: influence of calcium.
Thrombosis and haemostasis.
2012 Aug; 108(2):373-83. doi:
10.1160/th12-02-0120. [PMID: 22740162] - Shoken Lee, Yasunori Uchida, Kazuo Emoto, Masato Umeda, Osamu Kuge, Tomohiko Taguchi, Hiroyuki Arai. Impaired retrograde membrane traffic through endosomes in a mutant CHO cell defective in phosphatidylserine synthesis.
Genes to cells : devoted to molecular & cellular mechanisms.
2012 Aug; 17(8):728-36. doi:
10.1111/j.1365-2443.2012.01622.x. [PMID: 22747682] - Tessy T Sebastian, Ryan D Baldridge, Peng Xu, Todd R Graham. Phospholipid flippases: building asymmetric membranes and transport vesicles.
Biochimica et biophysica acta.
2012 Aug; 1821(8):1068-77. doi:
10.1016/j.bbalip.2011.12.007. [PMID: 22234261] - X Delabranche, A Berger, J Boisramé-Helms, F Meziani. Microparticles and infectious diseases.
Medecine et maladies infectieuses.
2012 Aug; 42(8):335-43. doi:
10.1016/j.medmal.2012.05.011. [PMID: 22766273] - Adam Orłowski, Michał Grzybek, Alex Bunker, Marta Pasenkiewicz-Gierula, Ilpo Vattulainen, Pekka T Männistö, Tomasz Róg. Strong preferences of dopamine and l-dopa towards lipid head group: importance of lipid composition and implication for neurotransmitter metabolism.
Journal of neurochemistry.
2012 Aug; 122(4):681-90. doi:
10.1111/j.1471-4159.2012.07813.x. [PMID: 22650805] - Ji Hong Hwang, In-Sok Hwang, Qing-He Liu, Eun-Rhan Woo, Dong Gun Lee. (+)-Medioresinol leads to intracellular ROS accumulation and mitochondria-mediated apoptotic cell death in Candida albicans.
Biochimie.
2012 Aug; 94(8):1784-93. doi:
10.1016/j.biochi.2012.04.010. [PMID: 22534194] - Gabriel G Llanos, Liliana M Araujo, Ignacio A Jiménez, Laila M Moujir, Isabel L Bazzocchi. Withaferin A-related steroids from Withania aristata exhibit potent antiproliferative activity by inducing apoptosis in human tumor cells.
European journal of medicinal chemistry.
2012 Aug; 54(?):499-511. doi:
10.1016/j.ejmech.2012.05.032. [PMID: 22705001] - James Mapes, Yu-Zen Chen, Anna Kim, Shohei Mitani, Byung-Ho Kang, Ding Xue. CED-1, CED-7, and TTR-52 regulate surface phosphatidylserine expression on apoptotic and phagocytic cells.
Current biology : CB.
2012 Jul; 22(14):1267-75. doi:
10.1016/j.cub.2012.05.052. [PMID: 22727702] - Yan Zhang, Haibin Wang, Eriko Kage-Nakadai, Shohei Mitani, Xiaochen Wang. C. elegans secreted lipid-binding protein NRF-5 mediates PS appearance on phagocytes for cell corpse engulfment.
Current biology : CB.
2012 Jul; 22(14):1276-84. doi:
10.1016/j.cub.2012.06.004. [PMID: 22727700] - Takeru Hayashi, Miki Senda, Hiroko Morohashi, Hideaki Higashi, Masafumi Horio, Yui Kashiba, Lisa Nagase, Daisuke Sasaya, Tomohiro Shimizu, Nagarajan Venugopalan, Hiroyuki Kumeta, Nobuo N Noda, Fuyuhiko Inagaki, Toshiya Senda, Masanori Hatakeyama. Tertiary structure-function analysis reveals the pathogenic signaling potentiation mechanism of Helicobacter pylori oncogenic effector CagA.
Cell host & microbe.
2012 Jul; 12(1):20-33. doi:
10.1016/j.chom.2012.05.010. [PMID: 22817985] - Jaeda Coutinho-Budd, Vladimir Ghukasyan, Mark J Zylka, Franck Polleux. The F-BAR domains from srGAP1, srGAP2 and srGAP3 regulate membrane deformation differently.
Journal of cell science.
2012 Jul; 125(Pt 14):3390-401. doi:
10.1242/jcs.098962. [PMID: 22467852] - Sudipta Hazra, Subhalakshmi Ghosh, Sukalyani Debnath, Scott Seville, Vijay Kumar Prajapati, Colin W Wright, Shyam Sundar, Banasri Hazra. Antileishmanial activity of cryptolepine analogues and apoptotic effects of 2,7-dibromocryptolepine against Leishmania donovani promastigotes.
Parasitology research.
2012 Jul; 111(1):195-203. doi:
10.1007/s00436-012-2818-9. [PMID: 22297912] - P E J Van Der Meijden, M Van Schilfgaarde, R Van Oerle, T Renné, H ten Cate, H M H Spronk. Platelet- and erythrocyte-derived microparticles trigger thrombin generation via factor XIIa.
Journal of thrombosis and haemostasis : JTH.
2012 Jul; 10(7):1355-62. doi:
10.1111/j.1538-7836.2012.04758.x. [PMID: 22537188] - Daniel Zin Hua Wong, Habsah Abdul Kadir, Choy Long Lee, Bey Hing Goh. Neuroprotective properties of Loranthus parasiticus aqueous fraction against oxidative stress-induced damage in NG108-15 cells.
Journal of natural medicines.
2012 Jul; 66(3):544-51. doi:
10.1007/s11418-011-0622-y. [PMID: 22318341] - S Courtney Frasch, Donna L Bratton. Emerging roles for lysophosphatidylserine in resolution of inflammation.
Progress in lipid research.
2012 Jul; 51(3):199-207. doi:
10.1016/j.plipres.2012.03.001. [PMID: 22465125] - Erfan Nur, Dees P Brandjes, Tom Teerlink, Hans-Martin Otten, Ronald P J Oude Elferink, Frits Muskiet, Ludo M Evers, Hugo ten Cate, Bart J Biemond, Ashley J Duits, John-John B Schnog. N-acetylcysteine reduces oxidative stress in sickle cell patients.
Annals of hematology.
2012 Jul; 91(7):1097-105. doi:
10.1007/s00277-011-1404-z. [PMID: 22318468] - Ming-Hui Chen, Shih-Yi Sheu, Chaolun Allen Chen, Jih-Terng Wang, Wen-Ming Chen. Idiomarina aquimaris sp. nov., isolated from the reef-building coral Isopora palifera.
International journal of systematic and evolutionary microbiology.
2012 Jul; 62(Pt 7):1536-1542. doi:
10.1099/ijs.0.035592-0. [PMID: 21856977] - Pierre-Emmanuel Rautou, Julie Bresson, Yannis Sainte-Marie, Anne-Clemence Vion, Valerie Paradis, Jean-Marie Renard, Cecile Devue, Christophe Heymes, Philippe Letteron, Laure Elkrief, Didier Lebrec, Dominique Valla, Alain Tedgui, Richard Moreau, Chantal M Boulanger. Abnormal plasma microparticles impair vasoconstrictor responses in patients with cirrhosis.
Gastroenterology.
2012 Jul; 143(1):166-76.e6. doi:
10.1053/j.gastro.2012.03.040. [PMID: 22465620] - Jie Yang, Ming-Zhu Ding, Bing-Zhi Li, Z Lewis Liu, Xin Wang, Ying-Jin Yuan. Integrated phospholipidomics and transcriptomics analysis of Saccharomyces cerevisiae with enhanced tolerance to a mixture of acetic acid, furfural, and phenol.
Omics : a journal of integrative biology.
2012 Jul; 16(7-8):374-86. doi:
10.1089/omi.2011.0127. [PMID: 22734833] - Ewa Stępień, Anna Kabłak-Ziembicka, Jarosław Czyż, Tadeusz Przewłocki, Maciej Małecki. Microparticles, not only markers but also a therapeutic target in the early stage of diabetic retinopathy and vascular aging.
Expert opinion on therapeutic targets.
2012 Jul; 16(7):677-88. doi:
10.1517/14728222.2012.691471. [PMID: 22616736] - Maarten E Tushuizen, Michaela Diamant, Erik G Peypers, Frans J Hoek, Robert J Heine, Augueste Sturk, Rienk Nieuwland. Postprandial changes in the phospholipid composition of circulating microparticles are not associated with coagulation activation.
Thrombosis research.
2012 Jul; 130(1):115-21. doi:
10.1016/j.thromres.2011.09.003. [PMID: 21962986] - I N Todor, N Yu Lukyanova, V F Chekhun. The lipid content of cisplatin- and doxorubicin-resistant MCF-7 human breast cancer cells.
Experimental oncology.
2012 Jul; 34(2):97-100. doi:
". [PMID: 23013760] - Nishith Gupta, Anne Hartmann, Richard Lucius, Dennis R Voelker. The obligate intracellular parasite Toxoplasma gondii secretes a soluble phosphatidylserine decarboxylase.
The Journal of biological chemistry.
2012 Jun; 287(27):22938-47. doi:
10.1074/jbc.m112.373639. [PMID: 22563079] - Endong Li, Mariko Noda, Yukiko Doi, Bijay Parajuli, Jun Kawanokuchi, Yoshifumi Sonobe, Hideyuki Takeuchi, Tetsuya Mizuno, Akio Suzumura. The neuroprotective effects of milk fat globule-EGF factor 8 against oligomeric amyloid β toxicity.
Journal of neuroinflammation.
2012 Jun; 9(?):148. doi:
10.1186/1742-2094-9-148. [PMID: 22742657] - Marcia Perez dos Santos Cabrera, Manoel Arcisio-Miranda, Renata Gorjão, Natália Bueno Leite, Bibiana Monson de Souza, Rui Curi, Joaquim Procopio, João Ruggiero Neto, Mario Sérgio Palma. Influence of the bilayer composition on the binding and membrane disrupting effect of Polybia-MP1, an antimicrobial mastoparan peptide with leukemic T-lymphocyte cell selectivity.
Biochemistry.
2012 Jun; 51(24):4898-908. doi:
10.1021/bi201608d. [PMID: 22630563] - Peggy P Ho, Jennifer L Kanter, Amanda M Johnson, Hrishikesh K Srinagesh, Eun-Ju Chang, Timothy M Purdy, Keith van Haren, William R Wikoff, Tobias Kind, Mohsen Khademi, Laura Y Matloff, Sirisha Narayana, Eun Mi Hur, Tamsin M Lindstrom, Zhigang He, Oliver Fiehn, Tomas Olsson, Xianlin Han, May H Han, Lawrence Steinman, William H Robinson. Identification of naturally occurring fatty acids of the myelin sheath that resolve neuroinflammation.
Science translational medicine.
2012 Jun; 4(137):137ra73. doi:
10.1126/scitranslmed.3003831. [PMID: 22674551] - S Prylutska, R Bilyy, M Overchuk, A Bychko, K Andreichenko, R Stoika, V Rybalchenko, Y Prylutskyy, N G Tsierkezos, U Ritter. Water-soluble pristine fullerenes C60 increase the specific conductivity and capacity of lipid model membrane and form the channels in cellular plasma membrane.
Journal of biomedical nanotechnology.
2012 Jun; 8(3):522-7. doi:
10.1166/jbn.2012.1404. [PMID: 22764423] - Rui Yang, Jie Pu, Juan Guo, Feng Xu, Zheng Zhang, Youshan Zhao, Xi Zhang, Shucheng Gu, Chunkang Chang, Xiao Li. The biological behavior of SDF-1/CXCR4 in patients with myelodysplastic syndrome.
Medical oncology (Northwood, London, England).
2012 Jun; 29(2):1202-8. doi:
10.1007/s12032-011-9943-7. [PMID: 21556934] - M L Rand, H Wang, F G Pluthero, A R Stafford, R Ni, N Vaezzadeh, A C Allison, W H A Kahr, J I Weitz, P L Gross. Diannexin, an annexin A5 homodimer, binds phosphatidylserine with high affinity and is a potent inhibitor of platelet-mediated events during thrombus formation.
Journal of thrombosis and haemostasis : JTH.
2012 Jun; 10(6):1109-19. doi:
10.1111/j.1538-7836.2012.04716.x. [PMID: 22463102] - Xia Xue, De-Fu Sun, Cui-Cui Sun, Hui-Ping Liu, Bin Yue, Cui-Rong Zhao, Hong-Xiang Lou, Xian-Jun Qu. Inhibitory effect of riccardin D on growth of human non-small cell lung cancer: in vitro and in vivo studies.
Lung cancer (Amsterdam, Netherlands).
2012 Jun; 76(3):300-8. doi:
10.1016/j.lungcan.2011.12.013. [PMID: 22261315] - Jie Yang, Song Yang, Ying-Jin Yuan. Integrated investigation of lipidome and related signaling pathways uncovers molecular mechanisms of tetramethylpyrazine and butylidenephthalide protecting endothelial cells under oxidative stress.
Molecular bioSystems.
2012 Jun; 8(6):1789-97. doi:
10.1039/c2mb05510d. [PMID: 22506278] - Grigoris T Gerotziafas, Patrick Van Dreden, Mourad Chaari, Vassiliki Galea, Amir Khaterchi, Francois Lionnet, Katice Stankovic-Stojanovic, Olivier Blanc-Brude, Barry Woodhams, Micheline Maier-Redelsperger, Robert Girot, Mohamed Hatmi, Ismail Elalamy. The acceleration of the propagation phase of thrombin generation in patients with steady-state sickle cell disease is associated with circulating erythrocyte-derived microparticles.
Thrombosis and haemostasis.
2012 Jun; 107(6):1044-52. doi:
10.1160/th11-10-0689. [PMID: 22535498] - Peng Liao, Wensen Liu, Hongyang Li, Hongwei Gao, Haiying Wang, Nan Li, Na Xu, Jiping Li, Jiayu Wan, Linna Liu, Yucheng Sun. Morphological changes of ricin toxin-induced apoptosis in human cervical cancer cells.
Toxicology and industrial health.
2012 Jun; 28(5):439-48. doi:
10.1177/0748233711414608. [PMID: 21937530] - P Kämpfer, N Lodders, K Martin, R Avendaño-Herrera. Flavobacterium chilense sp. nov. and Flavobacterium araucananum sp. nov., isolated from farmed salmonid fish.
International journal of systematic and evolutionary microbiology.
2012 Jun; 62(Pt 6):1402-1408. doi:
10.1099/ijs.0.033431-0. [PMID: 21828008] - Tommaso Neri, Cinzia Cordazzo, Yuri Carmazzi, Silvia Petrini, Cristina Balìa, Fabio Stefanelli, Angela Amoruso, Sandra Brunelleschi, Maria Cristina Breschi, Roberto Pedrinelli, Pierluigi Paggiaro, Alessandro Celi. Effects of peroxisome proliferator-activated receptor-γ agonists on the generation of microparticles by monocytes/macrophages.
Cardiovascular research.
2012 Jun; 94(3):537-44. doi:
10.1093/cvr/cvs125. [PMID: 22425902] - Mika Skeppholm, Fariborz Mobarrez, Karin Malmqvist, Håkan Wallén. Platelet-derived microparticles during and after acute coronary syndrome.
Thrombosis and haemostasis.
2012 Jun; 107(6):1122-9. doi:
10.1160/th11-11-0779. [PMID: 22371053] - Chim Kei Chan, Bey Hing Goh, Muhamad Noor Alfarizal Kamarudin, Habsah Abdul Kadir. Aqueous fraction of Nephelium ramboutan-ake rind induces mitochondrial-mediated apoptosis in HT-29 human colorectal adenocarcinoma cells.
Molecules (Basel, Switzerland).
2012 May; 17(6):6633-57. doi:
10.3390/molecules17066633. [PMID: 22728359] - Y C Zhou. Electrodiffusion of lipids on membrane surfaces.
The Journal of chemical physics.
2012 May; 136(20):205103. doi:
10.1063/1.4722196. [PMID: 22667591] - Joana Tulha, Fábio Faria-Oliveira, Cândida Lucas, Célia Ferreira. Programmed cell death in Saccharomyces cerevisiae is hampered by the deletion of GUP1 gene.
BMC microbiology.
2012 May; 12(?):80. doi:
10.1186/1471-2180-12-80. [PMID: 22617017] - Miriam Stoeber, Ina Karen Stoeck, Christine Hänni, Christopher Karl Ernst Bleck, Giuseppe Balistreri, Ari Helenius. Oligomers of the ATPase EHD2 confine caveolae to the plasma membrane through association with actin.
The EMBO journal.
2012 May; 31(10):2350-64. doi:
10.1038/emboj.2012.98. [PMID: 22505029] - Christopher F Monson, Xiao Cong, Aaron D Robison, Hudson P Pace, Chunming Liu, Matthew F Poyton, Paul S Cremer. Phosphatidylserine reversibly binds Cu2+ with extremely high affinity.
Journal of the American Chemical Society.
2012 May; 134(18):7773-9. doi:
10.1021/ja212138e. [PMID: 22548290] - Alberto Martín-Molina, César Rodríguez-Beas, Jordi Faraudo. Effect of calcium and magnesium on phosphatidylserine membranes: experiments and all-atomic simulations.
Biophysical journal.
2012 May; 102(9):2095-103. doi:
10.1016/j.bpj.2012.03.009. [PMID: 22824273] - Armen V Gyulkhandanyan, Asuman Mutlu, John Freedman, Valery Leytin. Markers of platelet apoptosis: methodology and applications.
Journal of thrombosis and thrombolysis.
2012 May; 33(4):397-411. doi:
10.1007/s11239-012-0688-8. [PMID: 22383127] - Vincent Pang, Laurent Counillon, Dominique Lagadic-Gossmann, Mallorie Poet, Jérôme Lacroix, Odile Sergent, Raheela Khan, Cyril Rauch. On the role of the difference in surface tensions involved in the allosteric regulation of NHE-1 induced by low to mild osmotic pressure, membrane tension and lipid asymmetry.
Cell biochemistry and biophysics.
2012 May; 63(1):47-57. doi:
10.1007/s12013-012-9340-7. [PMID: 22331497] - T A Kamalden, D Ji, N N Osborne. Rotenone-induced death of RGC-5 cells is caspase independent, involves the JNK and p38 pathways and is attenuated by specific green tea flavonoids.
Neurochemical research.
2012 May; 37(5):1091-101. doi:
10.1007/s11064-012-0713-5. [PMID: 22350517] - Jennifer Nelson, Lyndee L Francom, Lynn Anderson, Kelly Damm, Ryan Baker, Joseph Chen, Sarah Franklin, Amy Hamaker, Izadora Izidoro, Eric Moss, Mikayla Orton, Evan Stevens, Celestine Yeung, Allan M Judd, John D Bell. Investigation into the role of phosphatidylserine in modifying the susceptibility of human lymphocytes to secretory phospholipase A(2) using cells deficient in the expression of scramblase.
Biochimica et biophysica acta.
2012 May; 1818(5):1196-204. doi:
10.1016/j.bbamem.2012.01.005. [PMID: 22266334] - Oliver Holmes, Swetha Paturi, Wenjuan Ye, Michael S Wolfe, Dennis J Selkoe. Effects of membrane lipids on the activity and processivity of purified γ-secretase.
Biochemistry.
2012 May; 51(17):3565-75. doi:
10.1021/bi300303g. [PMID: 22489600] - Kazuhiro Tsuruma, Hiroki Shimazaki, Ken-Ichi Nakashima, Mika Yamauchi, Sou Sugitani, Masamitsu Shimazawa, Munekazu Iinuma, Hideaki Hara. Annatto prevents retinal degeneration induced by endoplasmic reticulum stress in vitro and in vivo.
Molecular nutrition & food research.
2012 May; 56(5):713-24. doi:
10.1002/mnfr.201100607. [PMID: 22648618] - J-S Song, K-M Lim, S Kang, J-Y Noh, K Kim, O-N Bae, J-H Chung. Procoagulant and prothrombotic effects of the herbal medicine, Dipsacus asper and its active ingredient, dipsacus saponin C, on human platelets.
Journal of thrombosis and haemostasis : JTH.
2012 May; 10(5):895-906. doi:
10.1111/j.1538-7836.2012.04685.x. [PMID: 22405282] - Bianca Stocco, Karina Toledo, Mirian Salvador, Michele Paulo, Natália Koyama, Maria Regina Torqueti Toloi. Dose-dependent effect of resveratrol on bladder cancer cells: chemoprevention and oxidative stress.
Maturitas.
2012 May; 72(1):72-8. doi:
10.1016/j.maturitas.2012.02.004. [PMID: 22386766] - Wen-Ming Chen, Fu-Sian Sheu, Chiu-Chung Young, Shih-Yi Sheu. Inhella fonticola sp. nov., isolated from spring water, and emended description of the genus Inhella.
International journal of systematic and evolutionary microbiology.
2012 May; 62(Pt 5):1048-1055. doi:
10.1099/ijs.0.034884-0. [PMID: 21685252] - Azza Al-Tawashi, Sung Yun Jung, Dou Liu, Bing Su, Jun Qin. Protein implicated in nonsyndromic mental retardation regulates protein kinase A (PKA) activity.
The Journal of biological chemistry.
2012 Apr; 287(18):14644-58. doi:
10.1074/jbc.m111.261875. [PMID: 22375002] - Shurong Zhong, FoSheng Hsu, Christopher J Stefan, Xiaochun Wu, Anamika Patel, Michael S Cosgrove, Yuxin Mao. Allosteric activation of the phosphoinositide phosphatase Sac1 by anionic phospholipids.
Biochemistry.
2012 Apr; 51(15):3170-7. doi:
10.1021/bi300086c. [PMID: 22452743] - Reet Järving, Aivar Lõokene, Reet Kurg, Liina Siimon, Ivar Järving, Nigulas Samel. Activation of 11R-lipoxygenase is fully Ca(2+)-dependent and controlled by the phospholipid composition of the target membrane.
Biochemistry.
2012 Apr; 51(15):3310-20. doi:
10.1021/bi201690z. [PMID: 22448896] - Nicole Y Davis, Linda C McPhail, David A Horita. The NOXO1β PX domain preferentially targets PtdIns(4,5)P2 and PtdIns(3,4,5)P3.
Journal of molecular biology.
2012 Apr; 417(5):440-53. doi:
10.1016/j.jmb.2012.01.058. [PMID: 22342885] - Aurore Jacquot, Cédric Montigny, Hanka Hennrich, Raphaëlle Barry, Marc le Maire, Christine Jaxel, Joost Holthuis, Philippe Champeil, Guillaume Lenoir. Phosphatidylserine stimulation of Drs2p·Cdc50p lipid translocase dephosphorylation is controlled by phosphatidylinositol-4-phosphate.
The Journal of biological chemistry.
2012 Apr; 287(16):13249-61. doi:
10.1074/jbc.m111.313916. [PMID: 22351780] - In-Sok Hwang, Juneyoung Lee, Hong-Guang Jin, Eun-Rhan Woo, Dong Gun Lee. Amentoflavone stimulates mitochondrial dysfunction and induces apoptotic cell death in Candida albicans.
Mycopathologia.
2012 Apr; 173(4):207-18. doi:
10.1007/s11046-011-9503-x. [PMID: 22210020] - Luciana Rabelo, Norberto Monteiro, Raphael Serquiz, Paula Santos, Ruth Oliveira, Adeliana Oliveira, Hugo Rocha, Ana Heloneida Morais, Adriana Uchoa, Elizeu Santos. A lactose-binding lectin from the marine sponge Cinachyrella apion (Cal) induces cell death in human cervical adenocarcinoma cells.
Marine drugs.
2012 Apr; 10(4):727-743. doi:
10.3390/md10040727. [PMID: 22690140] - Cheul Ho Park, Jae Woo Kim. Effect of advanced glycation end products on oxidative stress and senescence of trabecular meshwork cells.
Korean journal of ophthalmology : KJO.
2012 Apr; 26(2):123-31. doi:
10.3341/kjo.2012.26.2.123. [PMID: 22511839] - Kimihiko Sato, Chiaki Tanabe, Yoji Yonemura, Haruhiko Watahiki, Yimeng Zhao, Sosuke Yagishita, Maiko Ebina, Satoshi Suo, Eugene Futai, Masayuki Murata, Shoichi Ishiura. Localization of mature neprilysin in lipid rafts.
Journal of neuroscience research.
2012 Apr; 90(4):870-7. doi:
10.1002/jnr.22796. [PMID: 22183801] - Kornél Nagy, Viral Vishnuprasad Brahmbhatt, Olivier Berdeaux, Lionel Bretillon, Frédéric Destaillats, Niyazi Acar. Comparative study of serine-plasmalogens in human retina and optic nerve: identification of atypical species with odd carbon chains.
Journal of lipid research.
2012 Apr; 53(4):776-83. doi:
10.1194/jlr.d022962. [PMID: 22266369] - Leah R Hanson, Jared M Fine, John D Hoekman, Thuhien M Nguyen, Rachel B Burns, Paula M Martinez, Jens Pohl, William H Frey. Intranasal delivery of growth differentiation factor 5 to the central nervous system.
Drug delivery.
2012 Apr; 19(3):149-54. doi:
10.3109/10717544.2012.657720. [PMID: 22353012] - Anna Falanga, Carmen Julia Tartari, Marina Marchetti. Microparticles in tumor progression.
Thrombosis research.
2012 Apr; 129 Suppl 1(?):S132-6. doi:
10.1016/s0049-3848(12)70033-6. [PMID: 22682124] - Daniel E Otzen, Kristine Blans, Huabing Wang, Gary E Gilbert, Jan T Rasmussen. Lactadherin binds to phosphatidylserine-containing vesicles in a two-step mechanism sensitive to vesicle size and composition.
Biochimica et biophysica acta.
2012 Apr; 1818(4):1019-27. doi:
10.1016/j.bbamem.2011.08.032. [PMID: 21920348] - Anandita Roy, Parames C Sil. Tertiary butyl hydroperoxide induced oxidative damage in mice erythrocytes: Protection by taurine.
Pathophysiology : the official journal of the International Society for Pathophysiology.
2012 Apr; 19(2):137-48. doi:
10.1016/j.pathophys.2012.05.001. [PMID: 22626456]