Felosan (BioDeep_00000868642)

Main id: BioDeep_00000409335

 

PANOMIX_OTCML-2023


代谢物信息卡片


3-Pyridinecarboxamide, N-methyl- (9CI)

化学式: C7H8N2O (136.0637)
中文名称: N-甲基烟酰胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CNC(=O)C1=CN=CC=C1
InChI: InChI=1S/C7H8N2O/c1-8-7(10)6-3-2-4-9-5-6/h2-5H,1H3,(H,8,10)

描述信息

A - Alimentary tract and metabolism > A05 - Bile and liver therapy > A05A - Bile therapy > A05AB - Preparations for biliary tract therapy
N-Methylnicotinamide is an endogenous metabolite.
N-Methylnicotinamide is an endogenous metabolite.

同义名列表

19 个代谢物同义名

3-Pyridinecarboxamide, N-methyl- (9CI); 3-Pyridinecarboxamide, N-methyl-; N-Methyl-3-pyridinecarboxamide; N-Methylpyridine-3-carboxamide; Nicotinamide, N-methyl- (8CI); 3-(N-Methylcarbamoyl)pyridine; 3-(Methylcarbamoyl)pyridine; Nicotinic acid methylamide; Nicotinamide, N-methyl-; N -Methyl nicotineamide; N-Methylnicotinamide; EINECS 204-046-4; ZINC00404444; NSC 66521; 114-33-0; NSC66521; SR 4415; Felosan; N-Methylnicotinamide



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Jihong Chu, Ming Liu, Guoliang Dai, Changyin Li, Ting Wu, Jiandong Zou, Wenzheng Ju, Meijuan Xu. Simultaneous determination of nicotinamide and N1 -methylnicotinamide in human serum by LC-MS/MS to associate their serum concentrations with obesity. Biomedical chromatography : BMC. 2022 Feb; 36(2):e5261. doi: 10.1002/bmc.5261. [PMID: 34716608]
  • Letizia Bresciani, Michele Tassotti, Alice Rosi, Daniela Martini, Monica Antonini, Alessandra Dei Cas, Riccardo Bonadonna, Furio Brighenti, Daniele Del Rio, Pedro Mena. Absorption, Pharmacokinetics, and Urinary Excretion of Pyridines After Consumption of Coffee and Cocoa-Based Products Containing Coffee in a Repeated Dose, Crossover Human Intervention Study. Molecular nutrition & food research. 2020 09; 64(18):e2000489. doi: 10.1002/mnfr.202000489. [PMID: 32776430]
  • Junichiro Irie, Emi Inagaki, Masataka Fujita, Hideaki Nakaya, Masanori Mitsuishi, Shintaro Yamaguchi, Kazuya Yamashita, Shuhei Shigaki, Takashi Ono, Hideo Yukioka, Hideyuki Okano, Yo-Ichi Nabeshima, Shin-Ichiro Imai, Masato Yasui, Kazuo Tsubota, Hiroshi Itoh. Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men. Endocrine journal. 2020 Feb; 67(2):153-160. doi: 10.1507/endocrj.ej19-0313. [PMID: 31685720]
  • Venkatesh V Nemmara, Ronak Tilvawala, Ari J Salinger, Lacey Miller, Son Hong Nguyen, Eranthie Weerapana, Paul R Thompson. Citrullination Inactivates Nicotinamide- N-methyltransferase. ACS chemical biology. 2018 09; 13(9):2663-2672. doi: 10.1021/acschembio.8b00578. [PMID: 30044909]
  • Jian-Jun Chen, Shun-Jie Bai, Wen-Wen Li, Chan-Juan Zhou, Peng Zheng, Liang Fang, Hai-Yang Wang, Yi-Yun Liu, Peng Xie. Urinary biomarker panel for diagnosing patients with depression and anxiety disorders. Translational psychiatry. 2018 09; 8(1):192. doi: 10.1038/s41398-018-0245-0. [PMID: 30232320]
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  • Byong Chul Yoo, Sun-Young Kong, Sang-Geun Jang, Kyung-Hee Kim, Sun-A Ahn, Weon-Seo Park, Sohee Park, Tak Yun, Hyeon-Seok Eom. Identification of hypoxanthine as a urine marker for non-Hodgkin lymphoma by low-mass-ion profiling. BMC cancer. 2010 Feb; 10(?):55. doi: 10.1186/1471-2407-10-55. [PMID: 20175931]
  • Roman Lang, Anika Wahl, Thomas Skurk, Erkan Firat Yagar, Ludger Schmiech, Rudolf Eggers, Hans Hauner, Thomas Hofmann. Development of a hydrophilic liquid interaction chromatography-high-performance liquid chromatography-tandem mass spectrometry based stable isotope dilution analysis and pharmacokinetic studies on bioactive pyridines in human plasma and urine after coffee consumption. Analytical chemistry. 2010 Feb; 82(4):1486-97. doi: 10.1021/ac902616k. [PMID: 20073472]
  • Liang-Cai Zhao, Xiao-Dong Zhang, Shi-Xian Liao, Hong-Chang Gao, He-Yao Wang, Dong-Hai Lin. A metabonomic comparison of urinary changes in Zucker and GK rats. Journal of biomedicine & biotechnology. 2010; 2010(?):431894. doi: 10.1155/2010/431894. [PMID: 20981252]
  • Miroslav Dostalek, Klarissa D Hardy, Ginger L Milne, Jason D Morrow, Chi Chen, Frank J Gonzalez, Jun Gu, Xinxin Ding, Delinda A Johnson, Jeffrey A Johnson, Martha V Martin, F Peter Guengerich. Development of oxidative stress by cytochrome P450 induction in rodents is selective for barbiturates and related to loss of pyridine nucleotide-dependent protective systems. The Journal of biological chemistry. 2008 Jun; 283(25):17147-57. doi: 10.1074/jbc.m802447200. [PMID: 18442974]
  • Yvonne Tschuppert, Thierry Buclin, Laura E Rothuizen, Laurent A Decosterd, Jacques Galleyrand, Christine Gaud, Jérôme Biollaz. Effect of dronedarone on renal function in healthy subjects. British journal of clinical pharmacology. 2007 Dec; 64(6):785-91. doi: 10.1111/j.1365-2125.2007.02998.x. [PMID: 17662087]
  • Miki Hiasa, Takuya Matsumoto, Toshinori Komatsu, Hiroshi Omote, Yoshinori Moriyama. Functional characterization of testis-specific rodent multidrug and toxic compound extrusion 2, a class III MATE-type polyspecific H+/organic cation exporter. American journal of physiology. Cell physiology. 2007 Nov; 293(5):C1437-44. doi: 10.1152/ajpcell.00280.2007. [PMID: 17715386]
  • Laura K Schnackenberg, Jinchun Sun, Parvaneh Espandiari, Ricky D Holland, Joseph Hanig, Richard D Beger. Metabonomics evaluations of age-related changes in the urinary compositions of male Sprague Dawley rats and effects of data normalization methods on statistical and quantitative analysis. BMC bioinformatics. 2007 Nov; 8 Suppl 7(?):S3. doi: 10.1186/1471-2105-8-s7-s3. [PMID: 18047726]
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  • Praveen Vats, Som N Singh, Vijay K Singh, Radhey Shyam, Tribhuvan N Upadhyay, Shashi B Singh, Pratul K Banerjee. Changes in vitamin status of Indian Antarctic expeditioners during a one-month stay in Austral Summer. Wilderness & environmental medicine. 2007; 18(4):258-63. doi: 10.1580/06-weme-or-004r3.1. [PMID: 18076290]
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