Metacyl (BioDeep_00000868351)

Main id: BioDeep_00000658887

 

PANOMIX_OTCML-2023


代谢物信息卡片


InChI=1\C5H6N2O2\c1-3-2-4(8)7-5(9)6-3\h2H,1H3,(H2,6,7,8,9

化学式: C5H6N2O2 (126.04292559999999)
中文名称: 6-甲基尿嘧啶
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=CC(=O)NC(=O)N1
InChI: InChI=1S/C5H6N2O2/c1-3-2-4(8)7-5(9)6-3/h2H,1H3,(H2,6,7,8,9)

描述信息

D020011 - Protective Agents > D011837 - Radiation-Protective Agents
D005765 - Gastrointestinal Agents > D000897 - Anti-Ulcer Agents
D007155 - Immunologic Factors
6-Methyluracil (Pseudothymine), a metabolite of Uracil, can be used as an indicator of acetoacetyl-CoA (AACoA) accumulation. 6-Methyluracil exhibits antiradiation effect in vivo[1][2].
6-Methyluracil (Pseudothymine), a metabolite of Uracil, can be used as an indicator of acetoacetyl-CoA (AACoA) accumulation. 6-Methyluracil exhibits antiradiation effect in vivo[1][2].
6-Methyluracil (Pseudothymine), a metabolite of Uracil, can be used as an indicator of acetoacetyl-CoA (AACoA) accumulation. 6-Methyluracil exhibits antiradiation effect in vivo[1][2].

同义名列表

32 个代谢物同义名

InChI=1\C5H6N2O2\c1-3-2-4(8)7-5(9)6-3\h2H,1H3,(H2,6,7,8,9; 2(1H)-Pyrimidinone, 4-hydroxy-6-methyl- (8CI); 2(1H)-Pyrimidinone, 4-hydroxy-6-methyl-; 2,4(1H,3H)-Pyrimidinedione, 6-methyl-; 6-methylpyrimidine-2,4(1H,3H)-dione; 6-Methyl-2,4(1H,3H)-pyrimidinedione; 2,4-Dihydroxy-6-methylpyrimidine; 6-methyl-1H-pyrimidine-2,4-dione; 2,4-Pyrimidinediol, 6-methyl-; Pseudothymine (VAN); Uracil, 6-methyl-; EINECS 210-949-4; WLN: T6MVMVJ F1; AB-323\25048156; D115207_ALDRICH; 6-Methyluracil; Pseudothymine; ZINC00162484; AIDS-020783; AIDS020783; 78334-35-7; 15985-99-6; AI3-25472; HSDB 5508; SBB004256; SBB004254; AWD 23-15; 626-48-2; Methacyl; NSC 9456; Metacyl; NSC9456



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Igor Khalin, Ganna Kocherga. Arginine glutamate improves healing of radiation-induced skin ulcers in guinea pigs. International journal of radiation biology. 2013 Dec; 89(12):1108-15. doi: 10.3109/09553002.2013.817698. [PMID: 23786463]
  • Alexey V Solomonov, Evgeniy V Rumyantsev, Sergey P Ivanov, Boris A Kochergin, Elena V Antina. Spectroscopic studies of the supramolecular interactions between uracil and 5-hydroxy-6-methyluracil with bovine serum albumin and its bilirubin complex. The protein journal. 2013 Jun; 32(5):343-55. doi: 10.1007/s10930-013-9493-2. [PMID: 23657525]
  • K V Malyshev. [Antioxidant therapy with xymedon of patients with chronic osteomyelitis]. Vestnik khirurgii imeni I. I. Grekova. 2000; 159(4):59-63. doi: NULL. [PMID: 11011407]
  • S V Tarasenko, I P Aleksashina, V S Agapov, G M Trukhina, N A Liapunov. [The use of nitatsid and gipozol'-N in the combined treatment of acute inflammatory diseases of the maxillofacial area]. Stomatologiia. 2000; 79(2):17-9. doi: ". [PMID: 10812984]
  • V A Myshkin, Z G Khaĭbullina, S A Bashkatov, V P Krivonogov, D A Enikeev. [Effect of methyluracil and oxymethacil on free radical oxidation in model systems]. Biulleten' eksperimental'noi biologii i meditsiny. 1995 Aug; 120(8):142-4. doi: ". [PMID: 7579268]
  • N B Leonidov, E B Romanenko, A V Lebedev. [The effect of methyluracil polymorphism on lipid and antioxidant composition of rat tissues]. Voprosy meditsinskoi khimii. 1995 Mar; 41(2):32-5. doi: ". [PMID: 7793093]
  • Iu P Taran, L N Shishkina, L S Evseenko, G V Kukushkina. [Effect of 6-methyluracil on regulatory parameters of lipid peroxidation in thermal burn]. Patologicheskaia fiziologiia i eksperimental'naia terapiia. 1995 Jan; ?(1):40-3. doi: ". [PMID: 7610007]
  • C H Cromby, N J Manning, R J Pollitt, S Powell, M J Bennett. 6-Methyluracil excretion in 2-methylacetoacetyl-CoA thiolase deficiency and in two children with an unexplained recurrent ketoacidaemia. Journal of inherited metabolic disease. 1994; 17(1):81-4. doi: 10.1007/bf00735400. [PMID: 7914250]
  • Iu P Taran, L N Shishkina. [The antiradiation action of 6-methyluracil]. Radiobiologiia. 1993 Mar; 33(2):285-90. doi: . [PMID: 8502749]
  • Iu P Taran, L N Shishkina. [Effect of 6-methyluracil on various indicators of the lipid peroxidation regulation system in the body]. Voprosy meditsinskoi khimii. 1993 Jan; 39(1):37-41. doi: NULL. [PMID: 8498068]
  • S A Silaeva, V A Golenchenko, A V Gavril'chak, M V Onufriev, B I Khatsernova, N V Guliaeva, A B Shekhter. [Effect of carnosine and 4-methyluracil on the development of experimental hepatitis in rats]. Biokhimiia (Moscow, Russia). 1992 Sep; 57(9):1366-72. doi: . [PMID: 1467355]
  • L N Shishkina, Iu P Taran, S V Eliseeva, V G Bulgakov. [The effect of 6-methyluracil on oxidative reactions in model systems of varying degrees of complexity]. Izvestiia Akademii nauk. Seriia biologicheskaia. 1992 May; ?(3):350-7. doi: ". [PMID: 1304850]
  • M M Rasulov, I G Kuznetsov, S K Suslova, M V Velikaia, M G Voronkov. [Possible mechanisms of anti-ulcer action of silatranes]. Biulleten' eksperimental'noi biologii i meditsiny. 1990 Sep; 110(9):249-52. doi: ". [PMID: 2268706]
  • S A Silaeva, N V Guliaeva, B Ia Khatsernova, M V Onufriev, A Ia Nikolaev. [Effects of 4-methyluracil and carnosine on healing of skin wounds in rats]. Biulleten' eksperimental'noi biologii i meditsiny. 1990 Feb; 109(2):180-2. doi: NULL. [PMID: 2337657]
  • S N Udintsev, V P Shakhov. [Changes in clonogenic properties of bone marrow and transplantable mice tumor cells during combined use of cyclophosphane and biological response modifiers of adaptogenic origin]. Eksperimental'naia onkologiia. 1990; 12(6):55-6. doi: ". [PMID: 2261879]
  • O N Domashenko, Iu P Sotnik. [Evaluation of the cationic-lysosomal test in patients with pneumonia against a background of therapy]. Laboratornoe delo. 1989; ?(5):15-7. doi: ". [PMID: 2473250]
  • I G Kuznetsov, S K Suslova, M M Rasulov, V M Gukasov, E Ia Kaplan. [Effect of methyluracil on lipid peroxidation in the plasma and tissue homogenates from ulcer lesions of the gastric wall in rats]. Voprosy meditsinskoi khimii. 1987 May; 33(3):77-81. doi: NULL. [PMID: 3630022]
  • L A Leshchinskiĭ, V V Trusov, L V Anisimova, A A Barbakova. [Correction of protein metabolism in myocardial infarction according to the results of radionuclide studies with 131-albumin during during treatment with a number of drugs (retabolyl, methyluracil, panangin, strophanthin) and combinations of them]. Kardiologiia. 1984 Mar; 24(3):35-9. doi: . [PMID: 6727091]
  • G L Bilich, M M Myngerbaev. [Effect of 6-methyluracil on lipid metabolic indices and enzyme activity during ether and fluorothan anesthesia in children]. Anesteziologiia i reanimatologiia. 1984 Mar; ?(2):27-30. doi: ". [PMID: 6742495]
  • P G Krasnikov. [Use of an ointment containing levomycetin, methyluracil and aloe extract in plastic operations with transplantation of free flaps of the mucosa or skin]. Oftalmologicheskii zhurnal. 1984; ?(1):14-6. doi: ". [PMID: 6377157]
  • S V Sibiriak. [The effect of prodigiozan and methyluracil on adjuvant arthritis in rats]. Antibiotiki. 1983 Jun; 28(6):449-52. doi: NULL. [PMID: 6881955]
  • V P Gladchun. [Effect of adaptogenes on the immunological reactivity of patients with a history of acute pneumonia]. Vrachebnoe delo. 1983 Feb; ?(2):32-5. doi: ". [PMID: 6845694]