3-Pyridol (BioDeep_00000868280)

Main id: BioDeep_00000269141

 

PANOMIX_OTCML-2023


代谢物信息卡片


InChI=1\C5H5NO\c7-5-2-1-3-6-4-5\h1-4,7

化学式: C5H5NO (95.03711200000001)
中文名称: 3-羟基吡啶
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CN=C1)O
InChI: InChI=1S/C5H5NO/c7-5-2-1-3-6-4-5/h1-4,7H

描述信息

D020011 - Protective Agents > D000975 - Antioxidants
3-Hydroxypyridine is isolated from Bamboo grass. 3-Hydroxypyridine derivatives are structural analogues of vitamin B6 and have a wide range of pharmacological properties, such as antioxidant properties[1][2].
3-Hydroxypyridine is isolated from Bamboo grass. 3-Hydroxypyridine derivatives are structural analogues of vitamin B6 and have a wide range of pharmacological properties, such as antioxidant properties[1][2].

同义名列表

22 个代谢物同义名

InChI=1\C5H5NO\c7-5-2-1-3-6-4-5\h1-4,7; .beta.-Hydroxypyridine; beta-Hydroxypyridine; m-Hydroxypyridine; 3-HYDROXYPYRIDINE; 3-Pyridyl alcohol; EINECS 203-637-4; AC-907\25014060; H57009_ALDRICH; 3-Oxopyridine; ZINC00967325; Pyridin-3-ol; 3-Pyridinol; AIDS-020387; AIDS020387; 3-Pyridone; 3-Pyridol; SBB004391; AI3-19237; NSC 18470; NSC18470; 109-00-2



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Francisco J Hidalgo, Cristina M Lavado-Tena, Rosario Zamora. Formation of 3-hydroxypyridines by lipid oxidation products in the presence of ammonia and ammonia-producing compounds. Food chemistry. 2020 Oct; 328(?):127100. doi: 10.1016/j.foodchem.2020.127100. [PMID: 32464558]
  • Liang Xu, Zheming Ying, Wenjuan Wei, Dong Hao, Haibo Wang, Wenjie Zhang, Cuiyu Li, Mingyue Jiang, Xixiang Ying, Jing Liu. A novel alkaloid from Portulaca oleracea L. Natural product research. 2017 Apr; 31(8):902-908. doi: 10.1080/14786419.2016.1253081. [PMID: 27806650]
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  • Elena Synesiou, Lynnette D Fairbanks, H Anne Simmonds, Ewa M Slominska, Ryszard T Smolenski, Elizabeth A Carrey. 4-Pyridone-3-carboxamide-1-β-D-ribonucleoside triphosphate (4PyTP), a novel NAD metabolite accumulating in erythrocytes of uremic children: a biomarker for a toxic NAD analogue in other tissues?. Toxins. 2011 06; 3(6):520-37. doi: 10.3390/toxins3060520. [PMID: 22069723]
  • Terence G Hamill, Waisi Eng, Andrew Jennings, Richard Lewis, Steven Thomas, Suzanne Wood, Leslie Street, David Wisnoski, Scott Wolkenberg, Craig Lindsley, Sandra M Sanabria-Bohórquez, Shil Patel, Kerry Riffel, Christine Ryan, Jacquelynn Cook, Cyrille Sur, H Donald Burns, Richard Hargreaves. The synthesis and preclinical evaluation in rhesus monkey of [¹⁸F]MK-6577 and [¹¹C]CMPyPB glycine transporter 1 positron emission tomography radiotracers. Synapse (New York, N.Y.). 2011 Apr; 65(4):261-70. doi: 10.1002/syn.20842. [PMID: 20687108]
  • Ping-Chung Kuo, Yan-Yu Lai, Ying-Jie Chen, Wei-Hung Yang, Jason T C Tzen. Changes in volatile compounds upon aging and drying in oolong tea production. Journal of the science of food and agriculture. 2011 Jan; 91(2):293-301. doi: 10.1002/jsfa.4184. [PMID: 20945506]
  • I A Volchegorskiĭ, L M Rassokhina, I Iu Miroshnichenko. [Cerebroprotective effect of 3-oxypyridine and succinic acid derivatives in acute phase of alloxan-induced diabetes mellitus in rats]. Eksperimental'naia i klinicheskaia farmakologiia. 2011; 74(5):17-25. doi: . [PMID: 21809693]
  • A I Dolgushina. [Efficacy of emoxipine and mexidol in patients with chronic disorders of the digestive system and atherosclerosis of the abdominal aorta]. Eksperimental'naia i klinicheskaia farmakologiia. 2011; 74(12):11-4. doi: ". [PMID: 22379875]
  • I A Volchegorskii, L M Rassokhina, I Yu Miroshnichenko, K M Mester, P N Novoselov, T V Astakhova. Effect of pro- and antioxidants on insulin sensitivity and glucose tolerance. Bulletin of experimental biology and medicine. 2011 Jan; 150(3):327-32. doi: 10.1007/s10517-011-1134-1. [PMID: 21240346]
  • A P Vlasov, E A Nachkina, T I Grigor'eva, N Iu Leshchankina, V P Vlasova. [Cardioprotective and lipid-regulating effects of etoxidol with respect to surgical endotoxinemia]. Eksperimental'naia i klinicheskaia farmakologiia. 2009 Sep; 72(5):46-9. doi: ". [PMID: 19928577]
  • Makoto Ando, Nagaaki Sato, Tsuyoshi Nagase, Keita Nagai, Shiho Ishikawa, Hirobumi Takahashi, Norikazu Ohtake, Junko Ito, Mioko Hirayama, Yuko Mitobe, Hisashi Iwaasa, Akira Gomori, Hiroko Matsushita, Kiyoshi Tadano, Naoko Fujino, Sachiko Tanaka, Tomoyuki Ohe, Akane Ishihara, Akio Kanatani, Takehiro Fukami. Discovery of pyridone-containing imidazolines as potent and selective inhibitors of neuropeptide Y Y5 receptor. Bioorganic & medicinal chemistry. 2009 Aug; 17(16):6106-22. doi: 10.1016/j.bmc.2009.05.069. [PMID: 19616955]
  • Carsten Henneges, Dino Bullinger, Richard Fux, Natascha Friese, Harald Seeger, Hans Neubauer, Stefan Laufer, Christoph H Gleiter, Matthias Schwab, Andreas Zell, Bernd Kammerer. Prediction of breast cancer by profiling of urinary RNA metabolites using Support Vector Machine-based feature selection. BMC cancer. 2009 Apr; 9(?):104. doi: 10.1186/1471-2407-9-104. [PMID: 19344524]
  • N L Sakina, A M Golubkov, L D Smirnov, M A Ostrovsky, A E Dontsov. Studying the photoprotective activity of a new class of heteroaromatic antioxidants. Bulletin of experimental biology and medicine. 2009 Feb; 147(2):193-5. doi: 10.1007/s10517-009-0472-8. [PMID: 19513419]
  • E V Semenova. [Possibilities of pharmacological hepatopathy and correction of fat metabolism violations in diabetes mellitus type 1]. Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology. 2009; ?(6):138-42. doi: ". [PMID: 20201297]
  • Osama K Abou-Zied, Othman I K Al-Shihi. Characterization of subdomain IIA binding site of human serum albumin in its native, unfolded, and refolded states using small molecular probes. Journal of the American Chemical Society. 2008 Aug; 130(32):10793-801. doi: 10.1021/ja8031289. [PMID: 18642807]
  • Asumi Sakai, Kunitomo Watanabe, Mamoru Koketsu, Kazuhiko Akuzawa, Rie Yamada, Zhuan Li, Hidetaka Sadanari, Keiko Matsubara, Tsugiya Muroyama. Anti-human cytomegalovirus activity of constituents from Sasa albo-marginata (Kumazasa in Japan). Antiviral chemistry & chemotherapy. 2008; 19(3):125-32. doi: 10.1177/095632020801900303. [PMID: 19024629]
  • In-Kyung Kim, A M Abd El-Aty, Ho-Chul Shin, Hyang Burm Lee, In-Seon Kim, Jae-Han Shim. Analysis of volatile compounds in fresh healthy and diseased peppers (Capsicum annuum L.) using solvent free solid injection coupled with gas chromatography-flame ionization detector and confirmation with mass spectrometry. Journal of pharmaceutical and biomedical analysis. 2007 Nov; 45(3):487-94. doi: 10.1016/j.jpba.2007.07.025. [PMID: 17766077]
  • Luis B Rojas, Stéphane Quideau, Patrick Pardon, Zoubida Charrouf. Colorimetric evaluation of phenolic content and GC-MS characterization of phenolic composition of alimentary and cosmetic argan oil and press cake. Journal of agricultural and food chemistry. 2005 Nov; 53(23):9122-7. doi: 10.1021/jf051082j. [PMID: 16277411]
  • Hye-Young Kim, Derek A Pratt, Jennifer R Seal, Maikel Wijtmans, Ned A Porter. Lipid-soluble 3-pyridinol antioxidants spare alpha-tocopherol and do not efficiently mediate peroxidation of cholesterol esters in human low-density lipoprotein. Journal of medicinal chemistry. 2005 Nov; 48(22):6787-9. doi: 10.1021/jm0507173. [PMID: 16250637]
  • Rao-rao Li, Si-tong Yuan, Zhi-hong Li, Hai-lin Qin. [Studies on chemical constituents in Flos Sophorae Carbonisatus]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2005 Aug; 30(16):1255-7. doi: ". [PMID: 16245902]
  • I A Volchegorskiĭ, M G Moskvicheva, E N Chashchina. [Efficacy of derivatives of 3-hydroxypyridine and succinic acid in diabetic patients with the diabetic foot]. Klinicheskaia meditsina. 2004; 82(11):31-5. doi: . [PMID: 15656396]
  • Mark Woods, Shanrong Zhang, Von Howard Ebron, A Dean Sherry. pH-sensitive modulation of the second hydration sphere in lanthanide(III) tetraamide-DOTA complexes: a novel approach to smart MR contrast media. Chemistry (Weinheim an der Bergstrasse, Germany). 2003 Oct; 9(19):4634-40. doi: 10.1002/chem.200305159. [PMID: 14566868]
  • Zhongfa Liu, Lawrence M Sayre. Model studies on the modification of proteins by lipoxidation-derived 2-hydroxyaldehydes. Chemical research in toxicology. 2003 Feb; 16(2):232-41. doi: 10.1021/tx020095d. [PMID: 12588195]
  • G I Klebanov, O B Liubitskiĭ, O V Vasil'eva, Iu V Klimov, O B Penzulaeva, A S Tepliashin, M P Tolstykh, V K Promorenko, Iu A Vladimirov. [Antioxidant properties of 3-oxypyridine analogues: mexidol, emoxipin, proxipin]. Voprosy meditsinskoi khimii. 2001 May; 47(3):288-300. doi: ". [PMID: 11558311]
  • E Kindt, D T Rossi, K Gueneva-Boucheva, H Hallak. Quantitative method for biomarkers of collagen degradation using liquid chromatography tandem mass spectrometry. Analytical biochemistry. 2000 Jul; 283(1):71-6. doi: 10.1006/abio.2000.4625. [PMID: 10929810]
  • M M Iba, J Fung, J V Giannone, A B Okey. Comparative induction of CYP1A1 expression by pyridine and its metabolites. Archives of biochemistry and biophysics. 2000 Jun; 378(2):299-310. doi: 10.1006/abbi.2000.1826. [PMID: 10860547]
  • M P Graverand, A M Tron, M Ichou, M C Dallard, M Richard, D Uebelhart, E Vignon. Assessment of urinary hydroxypyridinium cross-links measurement in osteoarthritis. British journal of rheumatology. 1996 Nov; 35(11):1091-5. doi: 10.1093/rheumatology/35.11.1091. [PMID: 8948294]
  • G P Carlson. Comparison of the effects of pyridine and its metabolites on rat liver and kidney. Toxicology letters. 1996 Jun; 85(3):173-8. doi: 10.1016/0378-4274(96)03660-0. [PMID: 8644130]
  • G Kollerup, M Hansen, K Hørslev-Petersen. Urinary hydroxypyridinium cross-links of collagen in rheumatoid arthritis. Relation to disease activity and effects of methylprednisolone. British journal of rheumatology. 1994 Sep; 33(9):816-20. doi: 10.1093/rheumatology/33.9.816. [PMID: 8081665]
  • S Kamel, M Brazier, G Desmet, C Picard, I Mennecier, J Sebert. High-performance liquid chromatographic determination of 3-hydroxypyridinium derivatives as new markers of bone resorption. Journal of chromatography. 1992 Feb; 574(2):255-60. doi: 10.1016/0378-4347(92)80037-q. [PMID: 1618957]
  • E D Klimenko, L P Kobozeva, A B Michunskaia, N N Zolotov, I Iu Khabarina, O M Pozdniakov. [The effect of a 3-hydroxypyridine-class antioxidant on disorders of the microcirculatory system in experimental dyslipoproteinemia and its alimentary correction]. Biulleten' eksperimental'noi biologii i meditsiny. 1990 Mar; 109(3):234-7. doi: ". [PMID: 2364144]
  • L N Nerobkova, T A Voronina, A N Aliev, L D Smirnov, G N Kryzhanovskiĭ. [Electrophysiological and biochemical mechanisms of the anticonvulsant action of an antioxidant of the 3-hydroxypyridine class]. Biulleten' eksperimental'noi biologii i meditsiny. 1986 Dec; 102(12):663-5. doi: ". [PMID: 3801614]
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