AI3-60303 (BioDeep_00000866175)

Main id: BioDeep_00000018334

 

PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


InChI=1\C6H8N2\c1-5-3-8-6(2)4-7-5\h3-4H,1-2H

化学式: C6H8N2 (108.0687)
中文名称: 2,5-二甲基吡嗪
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=CN=C(C)C=N1
InChI: InChI=1S/C6H8N2/c1-5-3-8-6(2)4-7-5/h3-4H,1-2H3

描述信息

2,5-Dimethylpyrazine is an endogenous metabolite.
2,5-Dimethylpyrazine is an endogenous metabolite.

同义名列表

22 个代谢物同义名

InChI=1\C6H8N2\c1-5-3-8-6(2)4-7-5\h3-4H,1-2H; 2,5-Dimethylpyrazine (natural); 2,5-Dimethyl-1,4-diazine; 2,5-Dimethylparadiazine; Pyrazine, 2,5-dimethyl-; PYRAZINE,2,5-dimethyl; 2,5-DIMETHYLPYRAZINE; 2,5-Dimethylpiazine; WLN: T6N DNJ B1 E1; EINECS 204-618-3; W327204_ALDRICH; 175420_ALDRICH; FEMA No. 3272; ZINC00003182; 41535_FLUKA; CCRIS 2929; NSC 49139; ST5437415; AI3-60303; 123-32-0; NSC49139; 2,5-Dimethylpyrazine



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

6 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Jonathan I Kremer, Stephanie Pickard, Lara F Stadlmair, Anika Glaß-Theis, Leon Buckel, Tamara Bakuradze, Gerhard Eisenbrand, Elke Richling. Alkylpyrazines from Coffee are Extensively Metabolized to Pyrazine Carboxylic Acids in the Human Body. Molecular nutrition & food research. 2019 07; 63(14):e1801341. doi: 10.1002/mnfr.201801341. [PMID: 31125183]
  • Xiangyang Guo, Chuankui Song, Chi-Tang Ho, Xiaochun Wan. Contribution of l-theanine to the formation of 2,5-dimethylpyrazine, a key roasted peanutty flavor in Oolong tea during manufacturing processes. Food chemistry. 2018 Oct; 263(?):18-28. doi: 10.1016/j.foodchem.2018.04.117. [PMID: 29784304]
  • Simone B Soso, Jacek A Koziel. Characterizing the scent and chemical composition of Panthera leo marking fluid using solid-phase microextraction and multidimensional gas chromatography-mass spectrometry-olfactometry. Scientific reports. 2017 07; 7(1):5137. doi: 10.1038/s41598-017-04973-2. [PMID: 28698649]
  • Khaled Hamden, Henda Keskes, Sahla Belhaj, Kais Mnafgui, Abdelfattah Feki, Noureddine Allouche. Inhibitory potential of omega-3 fatty and fenugreek essential oil on key enzymes of carbohydrate-digestion and hypertension in diabetes rats. Lipids in health and disease. 2011 Dec; 10(?):226. doi: 10.1186/1476-511x-10-226. [PMID: 22142357]
  • Min Hee Park, Nam Gyu Seol, Pahn-Shick Chang, Suk Hoo Yoon, Jae Hwan Lee. Effects of roasting conditions on the physicochemical properties and volatile distribution in perilla oils (Perilla frutescens var. japonica). Journal of food science. 2011 Aug; 76(6):C808-16. doi: 10.1111/j.1750-3841.2011.02214.x. [PMID: 21623788]
  • Peiyou Qin, Tingjun Ma, Li Wu, Fang Shan, Guixing Ren. Identification of tartary buckwheat tea aroma compounds with gas chromatography-mass spectrometry. Journal of food science. 2011 Aug; 76(6):S401-7. doi: 10.1111/j.1750-3841.2011.02223.x. [PMID: 22417522]
  • Jian-Xu Zhang, Lixing Sun, Jin-Hua Zhang, Zhi-Yong Feng. Sex- and gonad-affecting scent compounds and 3 male pheromones in the rat. Chemical senses. 2008 Sep; 33(7):611-21. doi: 10.1093/chemse/bjn028. [PMID: 18515819]
  • Sugima Rappert, Renjie Li, Mariya Kokova, Mathias Antholz, Stephanie Nagorny, Wittko Francke, Rudolf Müller. Degradation of 2,5-dimethylpyrazine by Rhodococcus erythropolis strain DP-45 isolated from a waste gas treatment plant of a fishmeal processing company. Biodegradation. 2007 Oct; 18(5):585-96. doi: 10.1007/s10532-006-9091-5. [PMID: 17120096]
  • E V Daev, B P Surinov, A V Dukel'skaia, T M Marysheva. [Chromosomal abnormalities and spleenocyte production in laboratory mouse males after exposure to stress chemosignals]. Tsitologiia. 2007; 49(8):696-701. doi: NULL. [PMID: 17926567]
  • Roger N Thompson, Audrey Napier, Kennedy S Wekesa. Attenuation of the production of inositol 1,4,5-trisphosphate in the mouse vomeronasal organ by antibodies against the alphaq/11 subfamily of G-proteins. Chemical senses. 2006 Sep; 31(7):613-9. doi: 10.1093/chemse/bjj066. [PMID: 16757571]
  • J X Zhang, H A Soini, K E Bruce, D Wiesler, S K Woodley, M J Baum, M V Novotny. Putative chemosignals of the ferret (Mustela furo) associated with individual and gender recognition. Chemical senses. 2005 Nov; 30(9):727-37. doi: 10.1093/chemse/bji065. [PMID: 16221798]
  • Alan Willse, Anne M Belcher, George Preti, Jon H Wahl, Miranda Thresher, Peter Yang, Kunio Yamazaki, Gary K Beauchamp. Identification of major histocompatibility complex-regulated body odorants by statistical analysis of a comparative gas chromatography/mass spectrometry experiment. Analytical chemistry. 2005 Apr; 77(8):2348-61. doi: 10.1021/ac048711t. [PMID: 15828767]
  • Roger N Thompson, B K Robertson, Audrey Napier, Kennedy S Wekesa. Sex-specific responses to urinary chemicals by the mouse vomeronasal organ. Chemical senses. 2004 Nov; 29(9):749-54. doi: 10.1093/chemse/bjh076. [PMID: 15574810]
  • David C Robacker, Carol R Lauzon. Purine metabolizing capability of Enterobacter agglomerans affects volatiles production and attractiveness to Mexican fruit fly. Journal of chemical ecology. 2002 Aug; 28(8):1549-63. doi: 10.1023/a:1019920328062. [PMID: 12371809]
  • C McMahon, P M Guerin, Z Syed. 1-octen-3-ol isolated from bont ticks attracts Amblyomma variegatum. Journal of chemical ecology. 2001 Mar; 27(3):471-86. doi: 10.1023/a:1010328720035. [PMID: 11441439]
  • W Ma, Z Miao, M V Novotny. Role of the adrenal gland and adrenal-mediated chemosignals in suppression of estrus in the house mouse: the lee-boot effect revisited. Biology of reproduction. 1998 Dec; 59(6):1317-20. doi: 10.1095/biolreprod59.6.1317. [PMID: 9828173]
  • A Ohta, K Yamada. [Physiological and pharmacological activities of simple alkyl- and arylpyrazines]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 1997 Jul; 117(7):435-47. doi: 10.1248/yakushi1947.117.7_435. [PMID: 9261214]
  • K Yamada, A Shimizu, H Komatsu, R Sakata, A Ohta. Effects of 2,5-dimethylpyrazine on plasma testosterone and polyamines- and acid phosphatase-levels in the rat prostate. Biological & pharmaceutical bulletin. 1994 May; 17(5):730-1. doi: 10.1248/bpb.17.730. [PMID: 7920444]
  • B Jemiolo, M Novotny. Inhibition of sexual maturation in juvenile female and male mice by a chemosignal of female origin. Physiology & behavior. 1994 Mar; 55(3):519-22. doi: 10.1016/0031-9384(94)90110-4. [PMID: 8190771]
  • B Jemiolo, M Novotny. Long-term effect of a urinary chemosignal on reproductive fitness in female mice. Biology of reproduction. 1993 Apr; 48(4):926-9. doi: 10.1095/biolreprod48.4.926. [PMID: 8485258]
  • K Yamada, A Shimizu, A Ohta. Effects of dimethylpyrazine isomers on reproductive and accessory reproductive organs in male rats. Biological & pharmaceutical bulletin. 1993 Feb; 16(2):203-6. doi: 10.1248/bpb.16.203. [PMID: 8364457]
  • K Yamada, H Takahashi, A Ohta. Effects of 2,5-dimethylpyrazine on reproductive and accessory reproductive organs in female rats. Research communications in chemical pathology and pharmacology. 1992 Jan; 75(1):99-107. doi: NULL. [PMID: 1626128]