2150-43-8 (BioDeep_00000862349)

Main id: BioDeep_00000397454

 

PANOMIX_OTCML-2023


代谢物信息卡片


Benzoic acid, 3,4-dihydroxy-, methyl ester

化学式: C8H8O4 (168.0422568)
中文名称: 3,4-二羟基苯甲酸甲酯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC(=O)C1=CC(=C(C=C1)O)O
InChI: InChI=1S/C8H8O4/c1-12-8(11)5-2-3-6(9)7(10)4-5/h2-4,9-10H,1H3

描述信息

Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect[1].
Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect[1].

同义名列表

11 个代谢物同义名

Benzoic acid, 3,4-dihydroxy-, methyl ester; 3,4-Dihydroxybenzoic acid methyl ester; Protocatechuic acid, methyl ester; Methyl 3,4-dihydroxybenzoate; Methyl protocatechuate; ZINC00405329; ST5411547; NSC146458; 2150-43-8; Protocatechuic acid methyl ester; Methyl 3,4-dihydroxybenzoate



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Jia Hui Wang, Ke Qi Chen, Jun Xing Jiang, Huan Yong Li, Jun Ping Pan, Ji Yan Su, Lin Wang, Yang Hu, Xiang Nan Mi, Yi Rong Xin, Qin Gao, Xiang Long Zhao, Fei Xiao, Huan Min Luo. Excretion, Metabolism and Cytochrome P450 Inhibition of Methyl 3,4-Dihydroxybenzoate (MDHB): A Potential Candidate to Treat Neurodegenerative Diseases. European journal of drug metabolism and pharmacokinetics. 2020 Feb; 45(1):51-69. doi: 10.1007/s13318-019-00576-6. [PMID: 31602595]
  • Xiang Yuan, Huaixiu Wen, Yulei Cui, Minxia Fan, Zenggen Liu, Lijuan Mei, Yun Shao, Yiping Wang, Yanduo Tao. Phenolics from Lagotis brevituba Maxim. Natural product research. 2017 Feb; 31(3):362-366. doi: 10.1080/14786419.2016.1239090. [PMID: 27700190]
  • Bina S Siddiqui, Huma A Bhatti, Sabira Begum, Sobiya Perwaiz. Evaluation of the antimycobacterium activity of the constituents from Ocimum basilicum against Mycobacterium tuberculosis. Journal of ethnopharmacology. 2012 Oct; 144(1):220-2. doi: 10.1016/j.jep.2012.08.003. [PMID: 22982011]
  • Shaheen Faizi, Shahina Fayyaz, Samina Bano, Erum Yawar Iqbal, Lubna, Humaira Siddiqi, Aneela Naz. Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae. Journal of agricultural and food chemistry. 2011 Sep; 59(17):9080-93. doi: 10.1021/jf201611b. [PMID: 21780738]
  • Shaheen Faizi, Ahsana Dar, Humaira Siddiqi, Sabira Naqvi, Aneela Naz, Samina Bano, Lubna. Bioassay-guided isolation of antioxidant agents with analgesic properties from flowers of Tagetes patula. Pharmaceutical biology. 2011 May; 49(5):516-25. doi: 10.3109/13880209.2010.523006. [PMID: 21284510]
  • Wenqing Xu, Xiaojian Gong, Xin Zhou, Chao Zhao, Huaguo Chen. [Chemical constituents and bioactivity of Kalimeris indica]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2010 Dec; 35(23):3172-4. doi: 10.4268/cjcmm20102318. [PMID: 21355242]
  • Akiko Fujita, Hironori Fujitake, Koji Kawakami, Masato Nomura. Antioxidant activity of colored rice bran obtained at different milling yields. Journal of oleo science. 2010; 59(10):563-8. doi: 10.5650/jos.59.563. [PMID: 20877150]
  • Choong Je Ma, Young Choong Kim, Sang Hyun Sung. Compounds with neuroprotective activity from the medicinal plant Machilus thunbergii. Journal of enzyme inhibition and medicinal chemistry. 2009 Oct; 24(5):1117-21. doi: 10.1080/14756360802632971. [PMID: 19555186]
  • M Iqbal Choudhary, Saima Jalil, Sarfraz Ahmad Nawaz, Khalid Mohammed Khan, Rasool Bakhsh Tareen. Antiinflammatory and lipoxygenase inhibitory compounds from Vitex agnus-castus. Phytotherapy research : PTR. 2009 Sep; 23(9):1336-9. doi: 10.1002/ptr.2639. [PMID: 19173281]
  • Young-Won Chin, Hee-Byung Chai, William J Keller, A Douglas Kinghorn. Lignans and other constituents of the fruits of Euterpe oleracea (Acai) with antioxidant and cytoprotective activities. Journal of agricultural and food chemistry. 2008 Sep; 56(17):7759-64. doi: 10.1021/jf801792n. [PMID: 18656934]
  • Rudiyansyah, Mary J Garson. Secondary metabolites from the wood bark of Durio zibethinus and Durio kutejensis. Journal of natural products. 2006 Aug; 69(8):1218-21. doi: 10.1021/np050553t. [PMID: 16933881]
  • Luis B Rojas, Stéphane Quideau, Patrick Pardon, Zoubida Charrouf. Colorimetric evaluation of phenolic content and GC-MS characterization of phenolic composition of alimentary and cosmetic argan oil and press cake. Journal of agricultural and food chemistry. 2005 Nov; 53(23):9122-7. doi: 10.1021/jf051082j. [PMID: 16277411]
  • Uppuluri V Mallavadhani, Anita Mahapatra. A new aurone and two rare metabolites from the leaves of Diospyros melanoxylon. Natural product research. 2005 Jan; 19(1):91-7. doi: 10.1080/14786410410001704705. [PMID: 15700652]
  • Shizuka Saito, Jun Kawabata. Synergistic effects of thiols and amines on antiradical efficiency of protocatechuic acid. Journal of agricultural and food chemistry. 2004 Dec; 52(26):8163-8. doi: 10.1021/jf048970j. [PMID: 15612812]
  • Mitsuo Miyazawa, Teruo Oshima, Katsuya Koshio, Yumi Itsuzaki, Jun Anzai. Tyrosinase inhibitor from black rice bran. Journal of agricultural and food chemistry. 2003 Nov; 51(24):6953-6. doi: 10.1021/jf030388s. [PMID: 14611153]
  • Giuseppina Cioffi, Marta D'Auria, Alessandra Braca, Jeannette Mendez, Anibal Castillo, Ivano Morelli, Francesco De Simone, Nunziatina De Tommasi. Antioxidant and free-radical scavenging activity of constituents of the leaves of Tachigalia paniculata. Journal of natural products. 2002 Nov; 65(11):1526-9. doi: 10.1021/np0200764. [PMID: 12444671]
  • H S Yun-Choi, J H Kim, J R Lee. Potential inhibitors of platelet aggregation from plant sources, III. Journal of natural products. 1987 Nov; 50(6):1059-64. doi: 10.1021/np50054a008. [PMID: 3127544]